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Talanta. 2018;176:262\u201376.","journal-title":"Talanta"}],"container-title":["Clinical Pharmacokinetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40262-025-01502-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40262-025-01502-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40262-025-01502-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T10:45:50Z","timestamp":1746787550000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40262-025-01502-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,26]]},"references-count":41,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["1502"],"URL":"https:\/\/doi.org\/10.1007\/s40262-025-01502-7","relation":{},"ISSN":["0312-5963","1179-1926"],"issn-type":[{"value":"0312-5963","type":"print"},{"value":"1179-1926","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,26]]},"assertion":[{"value":"19 March 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 April 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Frank Klont gratefully acknowledges the funding provided by the Netherlands Organisation for Scientific Research NWO (domain Applied and Engineering Sciences) under Veni grant agreement no. 19060. The funder had no role in the study design, data collection, analysis, reporting, or the decision to submit for publication. Furthermore, the generation of the TransplantLines Food and Nutrition Biobank and Cohort Study (TxL-FN), trial registration number NCT02811835, was funded by the Top Institute Food and Nutrition, grant number A-1003. Continuation of the TransplantLines Food and Nutrition Biobank and Cohort Study was supported by grants from Astellas BV and Chiesi Pharmaceuticals BV and co-financed by the Dutch Ministry of Economic Affairs and Climate Policy by means of the public\u2013private partnership allowance made available by Top Sector Life Sciences & Health to stimulate public\u2013private partnerships. The funders had no role in the study design, data collection, analysis, reporting, or decision to submit for publication.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"The authors have no financial or proprietary interests in any material discussed in this article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study used existing data of KTRs and PLKD included in the TransplantLines Food and Nutrition Biobank and Cohort Study (NCT identifier NCT02811835), which was approved by the institutional review board of the University Medical Center Groningen (decision METc 2008\/186) and adhered to the Declaration of Helsinki.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"All participants provided written informed consent before study participation.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The pharmacometabolomic data used have been deposited in an open-access data repository, as can be found at:  []. Patient-level data for data on file in this manuscript are not available for sharing as there is a reasonable likelihood that individual patients could be re-identified. Further information can be requested from the authors.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Availability of data"}},{"value":"W.A.H., M.A.J.H., P.S., S.J.L.B., G.H., and F.K. wrote the manuscript. F.K. designed the research. W.A.H., M.A.J.H., and F.K. performed the research. W.A.H. and F.K. analyzed the data. S.J.L.B. and G.H. contributed new reagents\/analytical tools.","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Author contributions"}}]}}