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ANE was not involved in the selection of peer reviewers for the manuscript nor any of the subsequent editorial decisions. All remaining authors (SW, AH, and PM) have declared no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of Interest"}},{"value":"The data used for model development and validation may be found in Tables\n                      \n                      and\n                      \n                      .","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Data Availability Statement"}},{"value":"The original studies reporting sodium benzoate clinical PK data were Institutional Review Board-approved and no new enrolments occurred for this research.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Informed consent and assent, if applicable, were obtained from all participants of the original studies which took part in collecting the sodium benzoate data.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The open-source platforms by Open Systems Pharmacology, PK-Sim\n                      \u00ae\n                      and Mobi\n                      \u00ae\n                      were used.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code Availability"}},{"value":"SW: conceptualisation, methodology, data acquisition, scripting, data analysis and interpretation, high-quality figures, and manuscript preparation. AH: scripting, critical revisions of the manuscript. PM: supervision and critical revision of the manuscript. ANE: conceptualisation, supervision, critical revisions of the manuscript. All authors approved the final version of the manuscript.","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Authors\u2019 Contributions"}}]}}