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Keizer is an employee and stockholder of InsightRX, a company developing clinical decision support software. Astrid Heida, Elisabeth A.M. Cornelissen, Rob E. Aarnoutse, Brenda C.M. de Winter, Ron J. Keizer, Rob ter Heine, and Nynke G.L. Jager have no conflicts of interest that are directly relevant to the content of this article.","order":1,"name":"Ethics","label":"Conflicts of interest\/competing interests","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval was obtained in the Netherlands from the Medical Research Ethics Committee of Oost-Nederland (registration number: NL.85390.091.23). The study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.","order":2,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent was obtained for collection of the data.","order":3,"name":"Ethics","label":"Consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":4,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The data that support the findings of this study are available from the corresponding author upon reasonable request.","order":5,"name":"Ethics","label":"Availability of data and material","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The NONMEM control stream used for the tacrolimus PK model is available in the supplementary materials accompanying this work. The control stream for the selected mycophenolic acid PK model is accessible in the supplementary material of the original publication describing the development of that model.","order":6,"name":"Ethics","label":"Code availability","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Concept and design: NJ, RtH, AH, MC, RA; data collection: AH, MC; analysis and interpretation of data: NJ, RtH, AH, MC, RA; drafting of the manuscript: AH. All authors reviewed,  commented on, and approved the final submitted version of the manuscript.","order":7,"name":"Ethics","label":"Authors\u2019 contributions","group":{"name":"EthicsHeading","label":"Declarations"}}]}}