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The funders had no involvement in the design of the study; the collection, analyses, and interpretation of the data; the writing of the manuscript; or the publication decision.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"The authors declare no conflict of interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Anonymized data are available upon request by contacting the corresponding author.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Availability of data and material"}},{"value":"The study protocol (batch number: 2019KJCX065) was approved by the ethics committee of the Union Hospital, Fujian Medical University (Fuzhou, China). The patients\/participants provided their written informed consent to participate in this study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Written informed consent was obtained from all participants or their guardians in this trial.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Not applicable.","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code availability"}},{"value":"Hongbin Chen and Guiying Zeng were responsible for study conception and coordination, experiment design and performance, data collection and analysis, and manuscript drafting. Shufang Wu, Xinyan Chen, Weiwei Wu, and Sengpei Xie carried out data collection and analysis. Yingchun Xiao, Ronghua Chen, and Hui Chen carried out data analysis and revised the manuscript. All authors have read and approved the final submitted manuscript and agree to be accountable for the work.","order":9,"name":"Ethics","group":{"name":"EthicsHeading","label":"Author contributions"}}]}}