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Wu, and Jun Qi are employees of Shanghai Ark Biopharmaceutical Co., Ltd. All other authors declare they have no competing interests.","order":1,"name":"Ethics","label":"Conflict of Interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the respective institutional and\/or national research ethics committee. The study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki, and in compliance with the Good Clinical Practice (GCP) issued by The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH), the GCP issued by the NMPA and other relevant laws and regulations.","order":2,"name":"Ethics","label":"Ethics Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent was obtained from the parents or legal guardians of participants aged 6\u20137 years, who were not able to provide consent themselves, prior to any study procedures. For participants aged 8\u201312 years, written informed consent was obtained from their parents or legal guardians, and written informed assent was obtained from the participants.","order":3,"name":"Ethics","label":"Consent to Participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":4,"name":"Ethics","label":"Consent for Publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The datasets generated during and\/or analyzed during the current study do not include individual participant data. Study-level data are available from the corresponding author on reasonable request.","order":5,"name":"Ethics","label":"Availability of Data and Material","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":6,"name":"Ethics","label":"Code Availability","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"No AI tools were used in manuscript preparation, including drafting, editing, translation, summarization, data analysis, image generation, or other forms of assistance.","order":7,"name":"Ethics","label":"AI Use","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The following authors designed the study: Jing Liu, Tan Jia, Jim Z. Wu, Jun Qi, and Yi Zheng. The following authors gathered the data: Jing Liu, Ying Yang, Yi Wang, Jinjin Chen, Rongwang Yang, Yonghua Cui, Lili Zhang, Wenjing Liu, Fan He, Li Yang, Defeng Xu, Jinhua Sun, Aidina Aisikeer, Xiaoli Fan, Jingran Liu, Lei Wang, and Yi Zheng. The following authors analyzed the data: Jing Liu, Zhengqi Sun, Tan Jia, Jim Z. Wu, Jun Qi, and Yi Zheng. The following authors led writing of the paper: Jim Z. Wu, Jun Qi, and Tan Jia. All authors read and approved the final version.","order":8,"name":"Ethics","label":"Author Contributions","group":{"name":"EthicsHeading","label":"Declarations"}}]}}