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This is a database research study that has been conducted according to the guidelines of the Declaration of Helsinki (Fortaleza, Brazil 2013), Good Research Practice principles and guidelines, and the Real Decreto 957\/2020 (3 November, 2020) which regulates observational studies of medicines for human use.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The need for consent was waived by the Research Ethics Committee of IDIAPJGol as it is deemed unnecessary according to European legislation (Regulation [EU] 2016\/679).","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"A technical Appendix is provided in the ESM.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Availability of data and material"}},{"value":"The statistical code is available at the GitHub repository:\n                      \n                      .","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code availability"}},{"value":"All authors contributed to the study design. LB and AP: data analysis. LB: creation of tables and figures. LB: wrote the draft of the manuscript. LC, MGS, AA, AG, CV, CA, AP: supervision. All authors contributed to the article and approved the submitted version.\u00a0All authors read and approved the final version. Original protocol of the study [\n                      \n                      ].","order":9,"name":"Ethics","group":{"name":"EthicsHeading","label":"Author contributions"}}]}}