{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T21:09:23Z","timestamp":1787605763770,"version":"build-2736575974"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2019,9,3]],"date-time":"2019-09-03T00:00:00Z","timestamp":1567468800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,9,3]],"date-time":"2019-09-03T00:00:00Z","timestamp":1567468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Drugs Aging"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1007\/s40266-019-00701-9","type":"journal-article","created":{"date-parts":[[2019,9,3]],"date-time":"2019-09-03T01:04:26Z","timestamp":1567472666000},"page":"999-1005","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Appropriate Use of Laxatives in the Older Person"],"prefix":"10.1007","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8545-716X","authenticated-orcid":false,"given":"Lisa G.","family":"Pont","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murray","family":"Fisher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kylie","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,9,3]]},"reference":[{"issue":"4","key":"701_CR1","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1111\/j.1572-0241.2004.04114.x","volume":"99","author":"PD Higgins","year":"2004","unstructured":"Higgins PD, Johanson JF. Epidemiology of constipation in North America: a systematic review. Am J Gastroenterol. 2004;99(4):750\u20139.","journal-title":"Am J Gastroenterol"},{"issue":"8","key":"701_CR2","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1471-230X-8-5","volume":"12","author":"G Peppas","year":"2008","unstructured":"Peppas G, Alexiou VG, Mourtzoukou E, Falagas ME. Epidemiology of constipation in Europe and Oceania: a systematic review. BMC Gastroenterol. 2008;12(8):5.","journal-title":"BMC Gastroenterol"},{"key":"701_CR3","first-page":"919","volume":"10","author":"M Vazquez Roque","year":"2015","unstructured":"Vazquez Roque M, Bouras EP. Epidemiology and management of chronic constipation in elderly patients. Clin Interv Aging. 2015;10:919\u201330.","journal-title":"Clin Interv Aging"},{"issue":"8","key":"701_CR4","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1111\/j.1572-0241.2002.05843.x","volume":"97","author":"EJ Irvine","year":"2002","unstructured":"Irvine EJ, Ferrazzi S, Pare P, Thompson WG, Rance L. Health-related quality of life in functional GI disorders: focus on constipation and resource utilization. Am J Gastroenterol. 2002;97(8):1986\u201393.","journal-title":"Am J Gastroenterol"},{"issue":"15","key":"701_CR5","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1186\/s12876-015-0366-3","volume":"14","author":"R De Giorgio","year":"2015","unstructured":"De Giorgio R, Ruggeri E, Stanghellini V, Eusebi LH, Bazzoli F, Chiarioni G. Chronic constipation in the elderly: a primer for the gastroenterologist. BMC Gastroenterol. 2015;14(15):130.","journal-title":"BMC Gastroenterol"},{"issue":"3","key":"701_CR6","first-page":"299","volume":"84","author":"N Jamshed","year":"2011","unstructured":"Jamshed N, Lee ZE, Olden KW. Diagnostic approach to chronic constipation in adults. Am Fam Physician. 2011;84(3):299\u2013306.","journal-title":"Am Fam Physician"},{"key":"701_CR7","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.12920","author":"A Emmanuel","year":"2017","unstructured":"Emmanuel A, Mattace-Raso F, Neri MC, Petersen KU, Rey E, Rogers J. Constipation in older people: a consensus statement. Int J Clin Pract. 2017. https:\/\/doi.org\/10.1111\/ijcp.12920 .","journal-title":"Int J Clin Pract"},{"issue":"20","key":"701_CR8","doi-asserted-by":"crossref","first-page":"e10631","DOI":"10.1097\/MD.0000000000010631","volume":"97","author":"M Forootan","year":"2018","unstructured":"Forootan M, Bagheri N, Darvishi M. Chronic constipation: a review of literature. Medicine (Baltimore). 2018;97(20):e10631.","journal-title":"Medicine (Baltimore)"},{"issue":"2","key":"701_CR9","doi-asserted-by":"crossref","first-page":"86","DOI":"10.5694\/mja18.00241","volume":"209","author":"CJ Black","year":"2018","unstructured":"Black CJ, Ford AC. Chronic idiopathic constipation in adults: epidemiology, pathophysiology, diagnosis and clinical management. Med J Aust. 2018;209(2):86\u201391.","journal-title":"Med J Aust"},{"issue":"6","key":"701_CR10","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1111\/nmo.12335","volume":"26","author":"BE Lacy","year":"2014","unstructured":"Lacy BE, Hussain ZH, Mearin F. Treatment for constipation: new and old pharmacological strategies. Neurogastroenterol Motil. 2014;26(6):749\u201363.","journal-title":"Neurogastroenterol Motil"},{"issue":"6","key":"701_CR11","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1111\/j.1365-2036.1995.tb00433.x","volume":"9","author":"W Ashraf","year":"1995","unstructured":"Ashraf W, Park F, Lof J, Quigley EM. Effects of psyllium therapy on stool characteristics, colon transit and anorectal function in chronic idiopathic constipation. Aliment Pharmacol Ther. 1995;9(6):639\u201347.","journal-title":"Aliment Pharmacol Ther"},{"issue":"5","key":"701_CR12","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/j.1742-1241.1986.tb07949.x","volume":"40","author":"GC Fenn","year":"1986","unstructured":"Fenn GC, Wilkinson PD, Lee CE, Akbar FA. A general practice study of the efficacy of Regulan in functional constipation. Br J Clin Pract. 1986;40(5):192\u20137.","journal-title":"Br J Clin Pract"},{"key":"701_CR13","doi-asserted-by":"crossref","first-page":"273","DOI":"10.3109\/00365528709095900","volume":"22","author":"O Sculati","year":"1987","unstructured":"Sculati O, Giampiccoli G. Fibraform (80% of dietary fibre) in chronic constipated patients. Scand J Gastroenterol. 1987;22:273\u20137.","journal-title":"Scand J Gastroenterol"},{"issue":"8","key":"701_CR14","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1111\/j.1365-2036.2011.04602.x","volume":"33","author":"NC Suares","year":"2011","unstructured":"Suares NC, Ford AC. Systematic review: the effects of fibre in the management of chronic idiopathic constipation. Aliment Pharmacol Ther. 2011;33(8):895\u2013901.","journal-title":"Aliment Pharmacol Ther"},{"issue":"6","key":"701_CR15","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/S1543-5946(10)80003-0","volume":"8","author":"V Fleming","year":"2010","unstructured":"Fleming V, Wade WE. A review of laxative therapies for treatment of chronic constipation in older adults. Am J Geriatr Pharmacother. 2010;8(6):514\u201350.","journal-title":"Am J Geriatr Pharmacother"},{"issue":"Suppl 1","key":"701_CR16","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1038\/ajg.2014.187","volume":"109","author":"AC Ford","year":"2014","unstructured":"Ford AC, Moayyedi P, Lacy BE, Lembo AJ, Saito YA, Schiller LR, et al. American College of Gastroenterology monograph on the management of irritable bowel syndrome and chronic idiopathic constipation. Am J Gastroenterol. 2014;109(Suppl 1):S2\u201326.","journal-title":"Am J Gastroenterol"},{"issue":"10","key":"701_CR17","doi-asserted-by":"crossref","first-page":"807","DOI":"10.2165\/00002512-200825100-00001","volume":"25","author":"PF Gallagher","year":"2008","unstructured":"Gallagher PF, O\u2019Mahony D, Quigley EM. Management of chronic constipation in the elderly. Drugs Aging. 2008;25(10):807\u201321.","journal-title":"Drugs Aging"},{"issue":"12","key":"701_CR18","doi-asserted-by":"crossref","first-page":"517","DOI":"10.12968\/pnur.2017.28.12.517","volume":"28","author":"L Nazarko","year":"2017","unstructured":"Nazarko L. Understanding and managing constipation in older adults. Pract Nurs. 2017;28(12):517\u201324.","journal-title":"Pract Nurs"},{"issue":"5","key":"701_CR19","first-page":"163","volume":"9","author":"SS Rao","year":"2010","unstructured":"Rao SS, Go JT. Update on the management of constipation in the elderly: new treatment options. Clin Interv Aging. 2010;9(5):163\u201371.","journal-title":"Clin Interv Aging"},{"issue":"1","key":"701_CR20","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jpainsymman.2012.02.008","volume":"45","author":"Y Tarumi","year":"2013","unstructured":"Tarumi Y, Wilson MP, Szafran O, Spooner GR. Randomized, double-blind, placebo-controlled trial of oral docusate in the management of constipation in hospice patients. J Pain Symptom Manag. 2013;45(1):2\u201313.","journal-title":"J Pain Symptom Manag"},{"issue":"22","key":"701_CR21","doi-asserted-by":"crossref","first-page":"2716","DOI":"10.1001\/archinte.163.22.2716","volume":"163","author":"DM Fick","year":"2003","unstructured":"Fick DM, Cooper JW, Wade WE, Waller JL, Maclean JR, Beers MH. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med. 2003;163(22):2716\u201324.","journal-title":"Arch Intern Med"},{"issue":"4","key":"701_CR22","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1111\/j.1532-5415.2012.03922.x","volume":"60","author":"DM Fick","year":"2012","unstructured":"Fick DM, Semla TP. 2012 American Geriatrics Society Beers Criteria: new year, new criteria, new perspective. J Am Geriatr Soc. 2012;60(4):614\u20135.","journal-title":"J Am Geriatr Soc"},{"key":"701_CR23","unstructured":"Petticrew M, Watt I, Sheldon T. Systematic review of the effectiveness of laxatives in the elderly. Health Technol Assess. 1997;1(13):i\u2013iv, 1\u201352."},{"issue":"1","key":"701_CR24","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s11606-006-0003-5","volume":"12","author":"SM Tramonte","year":"1997","unstructured":"Tramonte SM, Brand MB, Mulrow CD, Amato MG, O\u2019Keefe ME, Ramirez G. The treatment of chronic constipation in adults. A systematic review. J Gen Intern Med. 1997;12(1):15\u201324.","journal-title":"J Gen Intern Med"},{"issue":"Suppl 1","key":"701_CR25","first-page":"S5","volume":"100","author":"LJ Brandt","year":"2005","unstructured":"Brandt LJ, Prather CM, Quigley EM, Schiller LR, Schoenfeld P, Talley NJ. Systematic review on the management of chronic constipation in North America. Am J Gastroenterol. 2005;100(Suppl 1):S5\u201321.","journal-title":"Am J Gastroenterol"},{"issue":"2","key":"701_CR26","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1136\/gut.44.2.226","volume":"44","author":"A Attar","year":"1999","unstructured":"Attar A, Lemann M, Ferguson A, Halphen M, Boutron MC, Flourie B, et al. Comparison of a low dose polyethylene glycol electrolyte solution with lactulose for treatment of chronic constipation. Gut. 1999;44(2):226\u201330.","journal-title":"Gut"},{"key":"701_CR27","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-019-01581-x","author":"A Nakajima","year":"2019","unstructured":"Nakajima A, Shinbo K, Oota A, Kinoshita Y. Polyethylene glycol 3350 plus electrolytes for chronic constipation: a 2-week, randomized, double-blind, placebo-controlled study with a 52-week open-label extension. J Gastroenterol. 2019. https:\/\/doi.org\/10.1007\/s00535-019-01581-x .","journal-title":"J Gastroenterol"},{"key":"701_CR28","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s40780-019-0133-7","volume":"5","author":"E Wakai","year":"2019","unstructured":"Wakai E, Ikemura K, Sugimoto H, Iwamoto T, Okuda M. Risk factors for the development of hypermagnesemia in patients prescribed magnesium oxide: a retrospective cohort study. J Pharm Health Care Sci. 2019;5:4.","journal-title":"J Pharm Health Care Sci"},{"issue":"6","key":"701_CR29","first-page":"500","volume":"92","author":"A Mounsey","year":"2015","unstructured":"Mounsey A, Raleigh M, Wilson A. Management of constipation in older adults. Am Fam Physician. 2015;92(6):500\u20134.","journal-title":"Am Fam Physician"},{"key":"701_CR30","unstructured":"U.S Food and Drug Administration. FDA warns of possible harm from exceeding recommended dose of over-the-counter sodium phosphate products to treat constipation. FDA Drug Safety Communication 2014 8\/1\/2014 [cited 1\/5\/19]. https:\/\/www.fda.gov\/media\/87428\/download"},{"issue":"8","key":"701_CR31","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1111\/j.1365-2982.2011.01709.x","volume":"23","author":"J Tack","year":"2011","unstructured":"Tack J, Muller-Lissner S, Stanghellini V, Boeckxstaens G, Kamm MA, Simren M, et al. Diagnosis and treatment of chronic constipation\u2013a European perspective. Neurogastroenterol Motil. 2011;23(8):697\u2013710.","journal-title":"Neurogastroenterol Motil"},{"issue":"3","key":"701_CR32","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.archger.2015.02.004","volume":"60","author":"BL Werth","year":"2015","unstructured":"Werth BL, Williams KA, Pont LG. A longitudinal study of constipation and laxative use in a community-dwelling elderly population. Arch Gerontol Geriatr. 2015;60(3):418\u201324.","journal-title":"Arch Gerontol Geriatr"},{"issue":"2","key":"701_CR33","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1097\/SGA.0000000000000144","volume":"40","author":"BL Werth","year":"2017","unstructured":"Werth BL, Williams KA, Pont LG. Laxative use and self-reported constipation in a community-dwelling elderly population: a community-based survey from Australia. Gastroenterol Nurs. 2017;40(2):134\u201341.","journal-title":"Gastroenterol Nurs"},{"issue":"4","key":"701_CR34","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1136\/qhc.0100268","volume":"10","author":"M Petticrew","year":"2001","unstructured":"Petticrew M, Rodgers M, Booth A. Effectiveness of laxatives in adults. Qual Health Care. 2001;10(4):268\u201373.","journal-title":"Qual Health Care"},{"issue":"2","key":"701_CR35","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1001\/jama.2015.16994","volume":"315","author":"A Wald","year":"2016","unstructured":"Wald A. Constipation: advances in diagnosis and treatment. JAMA. 2016;315(2):185\u201391.","journal-title":"JAMA"},{"issue":"17","key":"701_CR36","doi-asserted-by":"crossref","first-page":"2228","DOI":"10.1001\/jama.283.17.2228-JFD00003-2-1","volume":"283","author":"J Henney","year":"2000","unstructured":"Henney J. Withdrawal of troglitazone and cisapride. JAMA. 2000;283(17):2228.","journal-title":"JAMA"},{"issue":"2","key":"701_CR37","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1111\/j.1572-0241.2005.40749.x","volume":"100","author":"MA Kamm","year":"2005","unstructured":"Kamm MA, Muller-Lissner S, Talley NJ, Tack J, Boeckxstaens G, Minushkin ON, et al. Tegaserod for the treatment of chronic constipation: a randomized, double-blind, placebo-controlled multinational study. Am J Gastroenterol. 2005;100(2):362\u201372.","journal-title":"Am J Gastroenterol"},{"issue":"11","key":"701_CR38","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.1111\/j.1572-0241.2006.00789.x","volume":"101","author":"S Muller-Lissner","year":"2006","unstructured":"Muller-Lissner S, Kamm MA, Musoglu A, Earnest DL, Dunger-Baldauf C, Shetzline MA. Safety, tolerability, and efficacy of tegaserod over 13 months in patients with chronic constipation. Am J Gastroenterol. 2006;101(11):2558\u201369 (quiz 671).","journal-title":"Am J Gastroenterol"},{"issue":"9","key":"701_CR39","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1111\/j.1365-2982.2010.01533.x","volume":"22","author":"S Muller-Lissner","year":"2010","unstructured":"Muller-Lissner S, Rykx A, Kerstens R, Vandeplassche L. A double-blind, placebo-controlled study of prucalopride in elderly patients with chronic constipation. Neurogastroenterol Motil. 2010;22(9):991\u2013998, e255.","journal-title":"Neurogastroenterol Motil"},{"issue":"12","key":"701_CR40","doi-asserted-by":"crossref","first-page":"1256\u2013e117","DOI":"10.1111\/j.1365-2982.2009.01398.x","volume":"21","author":"M Camilleri","year":"2009","unstructured":"Camilleri M, Beyens G, Kerstens R, Robinson P, Vandeplassche L. Safety assessment of prucalopride in elderly patients with constipation: a double-blind, placebo-controlled study. Neurogastroenterol Motil. 2009;21(12):1256\u2013e117.","journal-title":"Neurogastroenterol Motil"},{"issue":"1","key":"701_CR41","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1177\/1756283X11423706","volume":"5","author":"EM Quigley","year":"2012","unstructured":"Quigley EM. Prucalopride: safety, efficacy and potential applications. Ther Adv Gastroenterol. 2012;5(1):23\u201330.","journal-title":"Ther Adv Gastroenterol"},{"issue":"9","key":"701_CR42","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1111\/j.1365-2036.2010.04456.x","volume":"32","author":"M Goldberg","year":"2010","unstructured":"Goldberg M, Li YP, Johanson JF, Mangel AW, Kitt M, Beattie DT, et al. Clinical trial: the efficacy and tolerability of velusetrag, a selective 5-HT4 agonist with high intrinsic activity, in chronic idiopathic constipation\u2014a 4-week, randomized, double-blind, placebo-controlled, dose-response study. Aliment Pharmacol Ther. 2010;32(9):1102\u201312.","journal-title":"Aliment Pharmacol Ther"},{"issue":"1","key":"701_CR43","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/j.1365-2982.2009.01378.x","volume":"22","author":"ML Manini","year":"2010","unstructured":"Manini ML, Camilleri M, Goldberg M, Sweetser S, McKinzie S, Burton D, et al. Effects of Velusetrag (TD-5108) on gastrointestinal transit and bowel function in health and pharmacokinetics in health and constipation. Neurogastroenterol Motil. 2010;22(1):42\u201349, e7\u20138.","journal-title":"Neurogastroenterol Motil"},{"key":"701_CR44","first-page":"191","volume":"8","author":"B Gras-Miralles","year":"2013","unstructured":"Gras-Miralles B, Cremonini F. A critical appraisal of lubiprostone in the treatment of chronic constipation in the elderly. Clin Interv Aging. 2013;8:191\u2013200.","journal-title":"Clin Interv Aging"},{"issue":"1","key":"701_CR45","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1124\/jpet.112.199430","volume":"344","author":"RW Busby","year":"2013","unstructured":"Busby RW, Kessler MM, Bartolini WP, Bryant AP, Hannig G, Higgins CS, et al. Pharmacologic properties, metabolism, and disposition of linaclotide, a novel therapeutic peptide approved for the treatment of irritable bowel syndrome with constipation and chronic idiopathic constipation. J Pharmacol Exp Ther. 2013;344(1):196\u2013206.","journal-title":"J Pharmacol Exp Ther"},{"issue":"5","key":"701_CR46","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/j.1532-5415.1978.tb01967.x","volume":"26","author":"JF Sanders","year":"1978","unstructured":"Sanders JF. Lactulose syrup assessed in a double-blind study of elderly constipated patients. J Am Geriatr Soc. 1978;26(5):236\u20139.","journal-title":"J Am Geriatr Soc"},{"issue":"2","key":"701_CR47","doi-asserted-by":"crossref","first-page":"334","DOI":"10.4292\/wjgpt.v7.i2.334","volume":"7","author":"M Izzy","year":"2016","unstructured":"Izzy M, Malieckal A, Little E, Anand S. Review of efficacy and safety of laxatives used in geriatrics. World J Gastrointest Pharmacol Ther. 2016;7(2):334\u201342.","journal-title":"World J Gastrointest Pharmacol Ther"},{"issue":"6","key":"701_CR48","first-page":"332","volume":"108","author":"F Mearin","year":"2016","unstructured":"Mearin F, Ciriza C, Minguez M, Rey E, Mascort JJ, Pena E, et al. Clinical practice guideline: irritable bowel syndrome with constipation and functional constipation in the adult. Rev Esp Enferm Dig. 2016;108(6):332\u201363.","journal-title":"Rev Esp Enferm Dig"},{"issue":"2","key":"701_CR49","first-page":"152","volume":"61","author":"BG Schuster","year":"2015","unstructured":"Schuster BG, Kosar L, Kamrul R. Constipation in older adults: stepwise approach to keep things moving. Can Fam Physician. 2015;61(2):152\u20138.","journal-title":"Can Fam Physician"},{"issue":"3","key":"701_CR50","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.gtc.2009.06.001","volume":"38","author":"EP Bouras","year":"2009","unstructured":"Bouras EP, Tangalos EG. Chronic constipation in the elderly. Gastroenterol Clin N Am. 2009;38(3):463\u201380.","journal-title":"Gastroenterol Clin N Am"}],"container-title":["Drugs & Aging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s40266-019-00701-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s40266-019-00701-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s40266-019-00701-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T21:44:53Z","timestamp":1721684693000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s40266-019-00701-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,3]]},"references-count":50,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["701"],"URL":"https:\/\/doi.org\/10.1007\/s40266-019-00701-9","relation":{},"ISSN":["1170-229X","1179-1969"],"issn-type":[{"value":"1170-229X","type":"print"},{"value":"1179-1969","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,3]]},"assertion":[{"value":"3 September 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"No sources of funding were used in the preparation of this review.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"Lisa Pont, Murray Fisher and Kylie Williams declare no conflicts of interest relevant to the content of this review.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}