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No funding has been received for the conduct of this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"Simona Lattanzi has received speaker's or consultancy fees from Eisai, GW Pharmaceuticals, and UCB Pharma and has served on advisory boards for Angelini, Arvelle Therapeutics, BIAL, and GW Pharmaceuticals. Valentina Chiesa has received speaker's or consultancy fees from Eisai, UCB Pharma, and Livanova. Fedele Dono has received speaker's fees from Eisai. Maria Paola Canevini has received speaker\u2019s or consultancy fees from Bial, EISAI, Italfarmaco, Sanofi, and UCB. All other authors have nothing to disclose.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was approved by the ethical committee at any participating center and conducted in accordance with the Declaration of Helsinki.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from every patient or legal representative.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Anonymized data will be shared by request from any qualified investigator.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Data availability"}},{"value":"Not applicable.","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code availability"}},{"value":"SL drafted the concept, analyzed data and wrote the manuscript. CC, NF, CR, EO, VC, FD, FD, MPC, GE, FP, EB, FR, AN, GP, DM, ER, PB, and AM collected data. All authors critically revised the work and contributed to the final manuscript. All authors approved the final manuscript for submission.","order":9,"name":"Ethics","group":{"name":"EthicsHeading","label":"Author contributions"}}]}}