{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T01:14:46Z","timestamp":1769130886106,"version":"3.49.0"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T00:00:00Z","timestamp":1660694400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T00:00:00Z","timestamp":1660694400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100000024","name":"CIHR","doi-asserted-by":"crossref","award":["MOP-136854"],"award-info":[{"award-number":["MOP-136854"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000024","name":"CIHR","doi-asserted-by":"crossref","award":["PJT 168914"],"award-info":[{"award-number":["PJT 168914"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Drugs Aging"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1007\/s40266-022-00972-9","type":"journal-article","created":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T04:02:45Z","timestamp":1660708965000},"page":"811-827","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Correlates of Opioid Use Among Ontario Long-Term Care Residents and Variation by Pain Frequency and Intensity: A Cross-sectional Analysis"],"prefix":"10.1007","volume":"39","author":[{"given":"Anita","family":"Iacono","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael A.","family":"Campitelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan E.","family":"Bronskill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David B.","family":"Hogan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Iaboni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura C.","family":"Maclagan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tara","family":"Gomes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mina","family":"Tadrous","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charity","family":"Evans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Gruneir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Guan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Hadjistavropoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilia","family":"Cotton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudeep S.","family":"Gill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dallas P.","family":"Seitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne","family":"Ho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7988-2899","authenticated-orcid":false,"given":"Colleen J.","family":"Maxwell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,8,17]]},"reference":[{"issue":"7","key":"972_CR1","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1007\/s00228-020-02878-0","volume":"76","author":"KL Lapane","year":"2020","unstructured":"Lapane KL, Hume AL, Morrison RA, Jesdale BM. Prescription analgesia and adjuvant use by pain severity at admission among nursing home residents with non-malignant pain. Eur J Clin Pharmacol. 2020;76(7):1021\u20138.","journal-title":"Eur J Clin Pharmacol"},{"issue":"3","key":"972_CR2","doi-asserted-by":"publisher","first-page":"E582","DOI":"10.9778\/cmajo.20190052","volume":"7","author":"A Iaboni","year":"2019","unstructured":"Iaboni A, Campitelli MA, Bronskill SE, Diong C, Kumar M, Maclagan LC, Gomes T, Tadrous M, Maxwell CJ. Time trends in opioid prescribing among Ontario long-term care residents: a repeated cross-sectional study. CMAJ Open. 2019;7(3):E582\u201398.","journal-title":"CMAJ Open"},{"issue":"1","key":"972_CR3","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1111\/jgs.15080","volume":"66","author":"JN Hunnicutt","year":"2018","unstructured":"Hunnicutt JN, Chrysanthopoulou SA, Ulbricht CM, Hume AL, Tjia J, Lapane KL. Prevalence of long-term opioid use in long-stay nursing home residents. J Am Geriatr Soc. 2018;66(1):48\u201355.","journal-title":"J Am Geriatr Soc"},{"issue":"10","key":"972_CR4","doi-asserted-by":"publisher","first-page":"2205","DOI":"10.1111\/jgs.15016","volume":"65","author":"LC Maclagan","year":"2017","unstructured":"Maclagan LC, Maxwell CJ, Gandhi S, Guan J, Bell CM, Hogan DB, Daneman N, Gill SS, Morris AM, Jeffs L, Campitelli MA, Seitz D, Bronskill SE. Frailty and potentially inappropriate medication use at nursing home transition. J Am Geriatr Soc. 2017;65(10):2205\u201312.","journal-title":"J Am Geriatr Soc"},{"issue":"2","key":"972_CR5","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1007\/s11096-020-01191-1","volume":"43","author":"AA Al-Qurain","year":"2021","unstructured":"Al-Qurain AA, Gebremichael LG, Khan MS, Williams DB, Mackenzie L, Phillips C, Russell P, Roberts MS, Wiese MD. Opioid prescribing and risk of drug-opioid interactions in older discharged patients with polypharmacy in Australia. Int J Clin Pharm. 2021;43(2):365\u201374.","journal-title":"Int J Clin Pharm"},{"issue":"1","key":"972_CR6","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1177\/8755122519867975","volume":"36","author":"M Jassal","year":"2020","unstructured":"Jassal M, Egan G, Dahri K. Opioid prescribing in the elderly: a systematic review. J Pharm Technol. 2020;36(1):28\u201340.","journal-title":"J Pharm Technol"},{"key":"972_CR7","doi-asserted-by":"crossref","unstructured":"The 2019 American Geriatrics Society Beers Criteria\u00ae Update Expert Panel. American Geriatrics Society 2019 updated AGS Beers Criteria\u00ae for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2019;67(4):674\u2013694.","DOI":"10.1111\/jgs.15767"},{"key":"972_CR8","doi-asserted-by":"publisher","first-page":"2663","DOI":"10.2147\/JPR.S270689","volume":"13","author":"CE Dube","year":"2020","unstructured":"Dube CE, Morrison RA, Mack DS, Jesdale BM, Nunes AP, Liu SH, Lapane KL. Prevalence of pain on admission by level of cognitive impairment in nursing homes. J Pain Res. 2020;13:2663\u201372.","journal-title":"J Pain Res"},{"issue":"6","key":"972_CR9","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1097\/j.pain.0000000000000887","volume":"158","author":"JN Hunnicutt","year":"2017","unstructured":"Hunnicutt JN, Ulbricht CM, Tjia J, Lapane KL. Pain and pharmacologic pain management in long-stay nursing home residents. Pain. 2017;158(6):1091\u20139.","journal-title":"Pain"},{"issue":"1","key":"972_CR10","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1002\/pds.4568","volume":"28","author":"JN Hunnicutt","year":"2019","unstructured":"Hunnicutt JN, Hume AL, Ulbricht CM, Tjia J, Lapane KL. Long-acting opioid initiation in US nursing homes. Pharmacoepidemiol Drug Saf. 2019;28(1):31\u20138.","journal-title":"Pharmacoepidemiol Drug Saf"},{"issue":"4","key":"972_CR11","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.jamda.2011.01.007","volume":"13","author":"KL Lapane","year":"2012","unstructured":"Lapane KL, Quilliam BJ, Chow W, Kim M. The association between pain and measures of well-being among nursing home residents. J Am Med Dir Assoc. 2012;13(4):344\u20139.","journal-title":"J Am Med Dir Assoc"},{"key":"972_CR12","doi-asserted-by":"crossref","unstructured":"Abdulla A, Adams N, Bone M, Elliott AM, Gaffin J, Jones D, Knaggs R, Martin D, Sampson L, Schofield P; British Geriatric Society. Guidance on the management of pain in older people. Age Ageing. 2013;42(Suppl 1):i1\u201357.","DOI":"10.1093\/ageing\/afs199"},{"issue":"9","key":"972_CR13","doi-asserted-by":"publisher","first-page":"5","DOI":"10.3928\/00989134-20190813-02","volume":"45","author":"LS Edelman","year":"2019","unstructured":"Edelman LS, Hemmert R. Opioid use in long-term care: guidelines and policy recommendations. J Gerontol Nurs. 2019;45(9):5\u201310.","journal-title":"J Gerontol Nurs"},{"issue":"6","key":"972_CR14","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1007\/s00228-017-2225-3","volume":"73","author":"TJ Oscanoa","year":"2017","unstructured":"Oscanoa TJ, Lizaraso F, Carvajal A. Hospital admissions due to adverse drug reactions in the elderly. A meta-analysis. Eur J Clin Pharmacol. 2017;73(6):759\u201370.","journal-title":"Eur J Clin Pharmacol"},{"issue":"1","key":"972_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/pds.4720","volume":"28","author":"MJM Vranken","year":"2019","unstructured":"Vranken MJM, Schutjens MDB, Mantel-Teeuwisse AK. The double opioid crisis: a call for balance. Pharmacoepidemiol Drug Saf. 2019;28(1):1\u20133.","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"972_CR16","doi-asserted-by":"publisher","unstructured":"Helvik AS, Bergh S, Benth JS, Selbaek G, Husebo BS, Tevik K. Pain in nursing home residents with dementia and its association to quality of life. Aging Ment Health. 2021;1\u201311: Online ahead of print. https:\/\/doi.org\/10.1080\/13607863.2021.1947968","DOI":"10.1080\/13607863.2021.1947968"},{"issue":"12","key":"972_CR17","doi-asserted-by":"publisher","first-page":"3","DOI":"10.3928\/00989134-20161110-01","volume":"42","author":"K Herr","year":"2016","unstructured":"Herr K, Arnstein P. The opioid epidemic and persistent pain management in older adults. J Gerontol Nurs. 2016;42(12):3\u20134.","journal-title":"J Gerontol Nurs"},{"key":"972_CR18","doi-asserted-by":"publisher","first-page":"431","DOI":"10.2147\/JPR.S239321","volume":"14","author":"WP Achterberg","year":"2021","unstructured":"Achterberg WP, Erdal A, Husebo BS, Kunz M, Lautenbacher S. Are chronic pain patients with dementia being undermedicated? J Pain Res. 2021;14:431\u20139.","journal-title":"J Pain Res"},{"issue":"9","key":"972_CR19","doi-asserted-by":"publisher","first-page":"1354","DOI":"10.1002\/gps.5526","volume":"36","author":"F La Frenais","year":"2021","unstructured":"La Frenais F, Vickerstaff V, Cooper C, Livingston G, Stone P, Sampson EL. Factors influencing prescription and administration of analgesic medication: a longitudinal study of people with dementia living in care homes. Int J Geriatr Psychiatry. 2021;36(9):1354\u201361.","journal-title":"Int J Geriatr Psychiatry"},{"issue":"1","key":"972_CR20","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.jamda.2020.04.029","volume":"22","author":"HB Mehta","year":"2021","unstructured":"Mehta HB, Kuo YF, Raji M, Li S, Westra J, Goodwin JS. Time trends in opioid use by dementia severity in long-term care nursing home residents. J Am Med Dir Assoc. 2021;22(1):124\u201331.","journal-title":"J Am Med Dir Assoc"},{"issue":"1","key":"972_CR21","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1186\/s12874-021-01327-5","volume":"21","author":"AP Nunes","year":"2021","unstructured":"Nunes AP, Zhao D, Jesdale WM, Lapane KL. Multiple imputation to quantify misclassification in observational studies of the cognitively impaired: an application for pain assessment in nursing home residents. BMC Med Res Methodol. 2021;21(1):132.","journal-title":"BMC Med Res Methodol"},{"issue":"9","key":"972_CR22","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1093\/gerona\/63.9.969","volume":"63","author":"MP Cadogan","year":"2008","unstructured":"Cadogan MP, Edelen MO, Lorenz KA, Jones M, Yosef J, Hascall T, Simon B, Harker JO, Ferrell B, Saliba D. The relationship of reported pain severity to perceived effect on function of nursing home residents. J Gerontol A Biol Sci Med Sci. 2008;63(9):969\u201373.","journal-title":"J Gerontol A Biol Sci Med Sci"},{"issue":"9","key":"972_CR23","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.1002\/jcph.731","volume":"56","author":"HK Greenblatt","year":"2016","unstructured":"Greenblatt HK, Greenblatt DJ. Use of antipsychotics for the treatment of behavioral symptoms of dementia. J Clin Pharmacol. 2016;56(9):1048\u201357.","journal-title":"J Clin Pharmacol"},{"key":"972_CR24","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d4065","volume":"343","author":"BS Husebo","year":"2011","unstructured":"Husebo BS, Ballard C, Sandvik R, Nilsen OB, Aarsland D. Efficacy of treating pain to reduce behavioural disturbances in residents of nursing homes with dementia: cluster randomised clinical trial. BMJ. 2011;343: d4065.","journal-title":"BMJ"},{"issue":"18","key":"972_CR25","doi-asserted-by":"publisher","first-page":"E659","DOI":"10.1503\/cmaj.170363","volume":"189","author":"JW Busse","year":"2017","unstructured":"Busse JW, Craigie S, Juurlink DN, Buckley DN, Wang L, Couban RJ, Agoritsas T, Aki EA, Carrasco-Labra A, Cooper L, Cull C, da Costa BR, Frank JW, Grant G, Iorio A, Persaud N, Stern S, Tugwell P, Vandvik PO, Guyatt GH. Guideline for opioid therapy and chronic noncancer pain. CMAJ. 2017;189(18):E659\u201366.","journal-title":"CMAJ"},{"key":"972_CR26","unstructured":"Canadian Institute for Health Information, Continuing Care Reporting System (CCRS) RAI-MDS 2.0\u00a9 Output Specifications Manuel, 2019-2020. Ottawa, Ont.: CIHI, 2019. https:\/\/secure.cihi.ca\/estore\/productFamily.htm?pf=PFC3942&lang=en&media=0"},{"key":"972_CR27","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/1472-6947-13-27","volume":"13","author":"JP Hirdes","year":"2013","unstructured":"Hirdes JP, Poss JW, Caldarelli H, Fries BE, Morris JN, Teare GF, Reidel K, Jutan N. An evaluation of data quality in Canada\u2019s Continuing Care Reporting System (CCRS): secondary analysis of Ontario data submitted between 1996\u20132011. BMC Med Inform Decis Mak. 2013;13:27.","journal-title":"BMC Med Inform Decis Mak"},{"issue":"8","key":"972_CR28","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.18441","volume":"4","author":"MA Campitelli","year":"2021","unstructured":"Campitelli MA, Bronskill SE, Maclagan LC, Harris DA, Cotton CA, Tadrous M, Gruneir A, Hogan DB, Maxwell CJ. Comparison of medication prescribing before and after the COVID-19 pandemic among nursing home residents in Ontario, Canada. JAMA Netw Open. 2021;4(8): e2118441.","journal-title":"JAMA Netw Open"},{"issue":"1","key":"972_CR29","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.jpainsymman.2011.12.285","volume":"45","author":"KL Lapane","year":"2013","unstructured":"Lapane KL, Quilliam BJ, Chow W, Kim MS. Pharmacologic management of non-cancer pain among nursing home residents. J Pain Symptom Manage. 2013;45(1):33\u201342.","journal-title":"J Pain Symptom Manage"},{"key":"972_CR30","doi-asserted-by":"crossref","unstructured":"Fries BE, Simon SE, Morris JN, Flodstrom C, Bookstein FL. Pain in U.S. nursing homes: validating a pain scale for the minimum data set. Gerontologist. 2001;41(2):173\u2013179.","DOI":"10.1093\/geront\/41.2.173"},{"issue":"2","key":"972_CR31","doi-asserted-by":"publisher","first-page":"M128","DOI":"10.1093\/gerona\/50A.2.M128","volume":"50A","author":"SL Hartmaier","year":"1995","unstructured":"Hartmaier SL, Sloane PD, Guess HA, Koch GG, Mitchell CM, Phillips CD. Validation of the minimum data set cognitive performance scale: agreement with the mini-mental state examination. J Gerontol A Biol Sci Med Sci. 1995;50A(2):M128\u201333.","journal-title":"J Gerontol A Biol Sci Med Sci"},{"issue":"11","key":"972_CR32","doi-asserted-by":"publisher","first-page":"M546","DOI":"10.1093\/gerona\/54.11.M546","volume":"54","author":"JN Morris","year":"1999","unstructured":"Morris JN, Fries BE, Morris SA. Scaling ADLs with the MDS. J Gerontol A Biol Sci Med Sci. 1999;54(11):M546\u201353.","journal-title":"J Gerontol A Biol Sci Med Sci"},{"issue":"2","key":"972_CR33","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1093\/ageing\/29.2.165","volume":"29","author":"AB Burrows","year":"2000","unstructured":"Burrows AB, Morris JN, Simon SE, Hirdes JP, Phillips C. Development of a Minimum Data Set-based depression rating scale for use in nursing homes. Age Ageing. 2000;29(2):165\u201372.","journal-title":"Age Ageing"},{"issue":"12","key":"972_CR34","doi-asserted-by":"publisher","first-page":"2298","DOI":"10.1111\/j.1532-5415.2008.02048.x","volume":"56","author":"CM Perlman","year":"2008","unstructured":"Perlman CM, Hirdes JP. The aggressive behavior scale: A new scale to measure aggression based on the Minimum Data Set. J Am Geriatr Soc. 2008;56(12):2298\u2013303.","journal-title":"J Am Geriatr Soc"},{"issue":"1","key":"972_CR35","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1111\/iwj.12535","volume":"14","author":"KY Woo","year":"2017","unstructured":"Woo KY, Sears K, Almost J, Wilson R, Whitehead M, VanDenKerkhof EG. Exploration of pressure ulcer and related skin problems across the spectrum of health care settings in Ontario using administrative data. Int Wound J. 2017;14(1):24\u201330.","journal-title":"Int Wound J"},{"issue":"25","key":"972_CR36","doi-asserted-by":"publisher","first-page":"3083","DOI":"10.1002\/sim.3697","volume":"28","author":"PC Austin","year":"2009","unstructured":"Austin PC. Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples. Stat Med. 2009;28(25):3083\u2013107.","journal-title":"Stat Med"},{"issue":"7","key":"972_CR37","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1093\/aje\/kwh090","volume":"159","author":"G Zou","year":"2004","unstructured":"Zou G. A modifed poisson regression approach to prospective studies with binary data. Am J Epidemiol. 2004;159(7):702\u20136.","journal-title":"Am J Epidemiol"},{"issue":"6","key":"972_CR38","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1177\/0962280211427759","volume":"22","author":"GY Zou","year":"2013","unstructured":"Zou GY, Donner A. Extension of the modifed poisson regression model to prospective studies with correlated binary data. Stat Methods Med Res. 2013;22(6):661\u201370.","journal-title":"Stat Methods Med Res"},{"issue":"3","key":"972_CR39","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/j.jamda.2018.12.022","volume":"20","author":"HM Roitto","year":"2019","unstructured":"Roitto HM, Kautiainen H, Aalto UL, \u00d6hman H, Laurila J, Pitk\u00e4l\u00e4 KH. Fouteen-year trends in the use of psychotropic medications, opioids and other sedatives among institutionalized older people in Helsinki, Finland. J Am Med Dir Assoc. 2019;20(3):305\u201311.","journal-title":"J Am Med Dir Assoc"},{"issue":"4","key":"972_CR40","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.3233\/JAD-190413","volume":"70","author":"C Jensen-Dahm","year":"2019","unstructured":"Jensen-Dahm C, Zakarias JK, Gasse C, Waldemar G. Geographical variation in opioid use in elderly patients with dementia: a nationwide study. J Alzheimers Dis. 2019;70(4):1209\u201316.","journal-title":"J Alzheimers Dis"},{"issue":"2","key":"972_CR41","doi-asserted-by":"publisher","first-page":"61","DOI":"10.3928\/19404921-20190122-01","volume":"12","author":"AL Gilmore-Bykovskyi","year":"2019","unstructured":"Gilmore-Bykovskyi AL, Block L, Hovanes M, Mirr J, Kolanowski A. Analgesic use patterns among patients with dementia during transitions from hospitals to skilled nursing facilities. Res Gerontol Nurs. 2019;12(2):61\u20139.","journal-title":"Res Gerontol Nurs"},{"issue":"4","key":"972_CR42","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1007\/s40266-021-00836-8","volume":"38","author":"KL Lapane","year":"2021","unstructured":"Lapane KL, Dub\u00e9 C, Hume AL, Tjia J, Jesdale BM, Pawasauskas J, Khodyakov D. Priority-setting to address the geriatric pharmacoparadox for pain management: a nursing home stakeholder delphi study. Drugs Aging. 2021;38(4):327\u201340.","journal-title":"Drugs Aging"},{"issue":"3","key":"972_CR43","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1017\/cjn.2020.13","volume":"47","author":"V Karnik","year":"2020","unstructured":"Karnik V, Farcy N, Zamorano C, Bruno V. Current status of pain management in Parkinson\u2019s disease. Can J Neurol Sci. 2020;47(3):336\u201343.","journal-title":"Can J Neurol Sci"},{"issue":"7","key":"972_CR44","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1007\/s40266-021-00867-1","volume":"38","author":"V Mylius","year":"2021","unstructured":"Mylius V, M\u00f6ller JC, Bohlhalter S, de Andrade DC, Lloret SP. Diagnosis and management of pain in Parkinson\u2019s disease: a new approach. Drugs Aging. 2021;38(7):559\u201377.","journal-title":"Drugs Aging"},{"issue":"3\u20134","key":"972_CR45","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1159\/000492221","volume":"51","author":"AR Qureshi","year":"2018","unstructured":"Qureshi AR, Rana AQ, Malik SH, Rizvi SFH, Akhter S, Vannabouathong C, Sarfraz Z, Rana R. Comprehensive examination of therapies for pain in Parkinson\u2019s disease: a systematic review and meta-analysis. Neuroepidemiology. 2018;51(3\u20134):190\u2013206.","journal-title":"Neuroepidemiology"},{"issue":"6","key":"972_CR46","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1093\/ageing\/afy104","volume":"47","author":"MD Saraiva","year":"2018","unstructured":"Saraiva MD, Suzuki GS, Lin SM, de Andrade DC, Jacob-Filho W, Suemoto CK. Persistent pain in a risk factor for frailty: a systematic review and meta-analysis from prospective longitudinal studies. Age Ageing. 2018;47(6):785\u201393.","journal-title":"Age Ageing"},{"key":"972_CR47","doi-asserted-by":"publisher","unstructured":"Hogan DB, Maxwell CJ. Frailty and unintended risks of medications. Curr Epidemiol Rep [Epidemiology of Aging Section] 2020; https:\/\/doi.org\/10.1007\/s40471-020-00226-5","DOI":"10.1007\/s40471-020-00226-5"},{"issue":"6","key":"972_CR48","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1093\/ageing\/afz109","volume":"48","author":"HJ Woodford","year":"2019","unstructured":"Woodford HJ, Fisher J. New horizons in deprescribing for older people. Age Ageing. 2019;48(6):768\u201375.","journal-title":"Age Ageing"},{"issue":"6","key":"972_CR49","doi-asserted-by":"publisher","first-page":"1293","DOI":"10.1111\/jgs.16394","volume":"68","author":"R Ng","year":"2020","unstructured":"Ng R, Lane N, Tanuseputro P, Mojaverian N, Talarico R, Wodchis WP, Bronskill SE, Hsu AT. Increasing complexity of new nursing home residents in Ontario, Canada: a serial cross-sectional study. J Am Geriatr Soc. 2020;68(6):1293\u2013300.","journal-title":"J Am Geriatr Soc"},{"issue":"3","key":"972_CR50","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1093\/gerona\/59.3.M281","volume":"59","author":"MP Cadogan","year":"2004","unstructured":"Cadogan MP, Schnelle JF, Yamamoto-Mitani N, Cabrera G, Simmons SF. A minimum data set prevalence of pain quality indicator: is it accurate and does it reflect differences in care processes? J Gerontol A Biol Sci Med Sci. 2004;59(3):281\u20135.","journal-title":"J Gerontol A Biol Sci Med Sci"},{"issue":"4","key":"972_CR51","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/j.jpainsymman.2004.01.001","volume":"27","author":"J Cohen-Mansfield","year":"2004","unstructured":"Cohen-Mansfield J. The adequacy of the minimum data set assessment of pain in cognitively impaired nursing home residents. J Pain Symptom Manage. 2004;27(4):343\u201351.","journal-title":"J Pain Symptom Manage"},{"issue":"1","key":"972_CR52","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1046\/j.1532-5415.2002.50021.x","volume":"50","author":"SE Fisher","year":"2002","unstructured":"Fisher SE, Burgio LD, Thorn BE, Allen-Burge R, Gerstle J, Roth DL, Allen SJ. Pain assessment and management in cognitively impaired nursing home residents: association of certified nursing assistant pain report, Minimum Data Set pain report, and analgesic medication use. J Am Geriatr Soc. 2002;50(1):152\u20136.","journal-title":"J Am Geriatr Soc"},{"issue":"4","key":"972_CR53","doi-asserted-by":"publisher","first-page":"1197","DOI":"10.1111\/j.1475-6773.2005.00400.x","volume":"40","author":"N Wu","year":"2005","unstructured":"Wu N, Miller SC, Lapane K, Roy J, Mor V. The quality of the quality indicator of pain derived from the minimum data set. Health Serv Res. 2005;40(4):1197\u2013216.","journal-title":"Health Serv Res"},{"issue":"10","key":"972_CR54","doi-asserted-by":"publisher","first-page":"1963","DOI":"10.1111\/jgs.15519","volume":"66","author":"SE Bronskill","year":"2018","unstructured":"Bronskill SE, Campitelli MA, Iaboni A, Herrmann N, Guan J, Maclagan LC, Watt J, Rochon PA, Morris AM, Jeffs L, Bell CM, Maxwell CJ. Low-dose trazodone, benzodiazepines, and fall-related injuries in nursing homes: a matched-cohort study. J Am Geriatr Soc. 2018;66(10):1963\u201371.","journal-title":"J Am Geriatr Soc"},{"issue":"10","key":"972_CR55","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002396","volume":"14","author":"T Gomes","year":"2017","unstructured":"Gomes T, Juurlink DN, Antoniou T, Mamdani MM, Paterson JM, van den Brink W. Gabapentin, opioids, and the risk of opioid-related death: a population-based nested case\u2013control study. PLoS Med. 2017;14(10): e1002396.","journal-title":"PLoS Med"},{"issue":"10","key":"972_CR56","doi-asserted-by":"publisher","first-page":"732","DOI":"10.7326\/M18-1136","volume":"169","author":"T Gomes","year":"2018","unstructured":"Gomes T, Greaves S, van den Brink W, Antoniou T, Mamdani MM, Paterson JM, Martins D. Juurlink DN Pregabalin and the risk for opioid-related death: a nested case\u2013control study. Ann Intern Med. 2018;169(10):732\u20134.","journal-title":"Ann Intern Med"},{"issue":"12","key":"972_CR57","doi-asserted-by":"publisher","first-page":"1326","DOI":"10.1016\/j.jagp.2017.08.014","volume":"25","author":"JC Macri","year":"2017","unstructured":"Macri JC, Iaboni A, Kirkham JG, Maxwell C, Gill SS, Vasudev A, Whitehead M, Seitz DP. Association between antidepressants and fall-related injuries among long-term care residents. Am J Geriatr Psychiatry. 2017;25(12):1326\u201336.","journal-title":"Am J Geriatr Psychiatry"},{"key":"972_CR58","doi-asserted-by":"publisher","unstructured":"Mbrah AK, Nunes AP, Hume AL, Zhao D, Jesdale BM, Bova C, Lapane KL. Prevalence and treatment of neuropathic pain diagnoses among U.S. nursing home residents. Pain. 2021. https:\/\/doi.org\/10.1097\/j.pain.0000000000002525 (Online ahead of print)","DOI":"10.1097\/j.pain.0000000000002525"},{"issue":"2","key":"972_CR59","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1007\/s40266-019-00732-2","volume":"37","author":"D Zhao","year":"2020","unstructured":"Zhao D, Shridharmurthy D, Alcusky MJ, Yuan Y, Nunes AP, Hume AL, Baek J, Lapane KL. The prevalence and factors associated with antiepileptic drug use in US nursing home residents. Drugs Aging. 2020;37(2):137\u201345.","journal-title":"Drugs Aging"},{"issue":"5","key":"972_CR60","doi-asserted-by":"publisher","first-page":"453.e1","DOI":"10.1016\/j.jamda.2017.01.024","volume":"18","author":"AP Rajkumar","year":"2017","unstructured":"Rajkumar AP, Ballard C, Fossey J, Orrell M, Moniz-Cook E, Woods RT, Murray J, Whitaker R, Stafford J, Knapp M, Romeo R, Woodward-Carlton B, Khan Z, Testad I, Corbett A. Epidemiology of pain in people with dementia living in care homes: longitudinal course, prevalence and treatment implications. J Am Med Dir Assoc. 2017;18(5):453.e1-453.e6.","journal-title":"J Am Med Dir Assoc"}],"container-title":["Drugs &amp; Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40266-022-00972-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40266-022-00972-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40266-022-00972-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,15]],"date-time":"2025-04-15T11:08:58Z","timestamp":1744715338000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40266-022-00972-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,17]]},"references-count":60,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["972"],"URL":"https:\/\/doi.org\/10.1007\/s40266-022-00972-9","relation":{},"ISSN":["1170-229X","1179-1969"],"issn-type":[{"value":"1170-229X","type":"print"},{"value":"1179-1969","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,17]]},"assertion":[{"value":"26 July 2022","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 August 2022","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This research was funded by the Canadian Institutes of Health Research (CIHR) through two operating grants (Exploring frailty and its role in the assessment of high-risk medications and risk of poor health outcomes in vulnerable populations\u2014MOP\u2010136854 and Understanding and optimizing opioid use in long-term care\u2014PJT-168914). This study was supported by ICES, which is funded by an annual grant from the Ontario Ministry of Health (MOH) and the Ministry of Long\u2010Term Care (MLTC). Parts of this material are based on data and\/or information compiled and provided by the Canadian Institute for Health Information (CIHI). However, the analyses, conclusions, opinions, and statements expressed herein are solely those of the authors and do not reflect those of the funding or data sources; no endorsement by ICES, the MOH, MLTC, or CIHI is intended or should be inferred.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"The study sponsors provided the operating costs and infrastructure to support the research. No funding bodies had any role in the study design, data collection, analysis, decision to publish, or preparation of the manuscript.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Sponsor\u2019s role"}},{"value":"The authors have no conflicts of interest to report.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study received ethics clearance by the University of Waterloo Human Research Ethics Committee (# 42355).","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The dataset from this study is held securely in coded form at ICES. While legal data sharing agreements prohibit ICES from making the dataset publicly available, access may be granted to those who meet pre-specified criteria for confidential access, available at  (email: das@ices.on.ca).","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Availability of data and material"}},{"value":"The full dataset creation plan and underlying analytic code are available from the authors upon request, understanding that the computer programs may rely upon coding templates or macros that are unique to ICES and are therefore either inaccessible or may require modification.","order":9,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code availability"}}]}}