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Eisai was involved in the study design, data collection, data analysis, and preparation of the manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"Dr. Gotfried has received research support and\/or speaker fees from Eisai Inc., Idorsia, Jazz Pharmaceuticals, and Merck. Dr. Auerbach declares he has no conflicts of interest. Dr. Dang-Vu has been a consultant and\/or speaker for and\/or has received research support from Eisai Inc., Jazz Pharmaceuticals, and Paladin Labs. Dr. Mishima has been a consultant and\/or speaker for and\/or has received research support from Eisai Co., Ltd., MSD, Nobelpharma, and Takeda Pharmaceutical Limited. Drs Kumar and Moline are employees of Eisai Inc. Dr. Malhotra is a former employee of Eisai Inc.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interests"}},{"value":"The datasets generated during and\/or analyzed during the current study are available from the corresponding author upon reasonable request.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Availability of data"}},{"value":"The study protocols were approved by relevant institutional review boards and independent ethics committees. The studies adhered to Good Clinical Practice guidelines, the Declaration of Helsinki and local regulations.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"All study participants provided written informed consent prior to participation.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Not applicable.","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code availability"}},{"value":"Study concept and design: Margaret Moline. Acquisition of subjects and\/or data: Mark H. Gotfried. Analysis and interpretation of data: all authors. Preparation of manuscript: all authors. All authors have read and approved the final submitted manuscript and agree to be held accountable for the work.","order":9,"name":"Ethics","group":{"name":"EthicsHeading","label":"Author contributions"}}]}}