{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T20:39:11Z","timestamp":1793997551079,"version":"4.8.0"},"reference-count":65,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T00:00:00Z","timestamp":1749772800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T00:00:00Z","timestamp":1749772800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Drugs Aging"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1007\/s40266-025-01219-z","type":"journal-article","created":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T12:16:13Z","timestamp":1749816973000},"page":"699-707","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Scabies in older adults: What Is New in Diagnosis and Treatment?"],"prefix":"10.1007","volume":"42","author":[{"given":"Vasiliki","family":"Kourouni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Callum D.","family":"Verran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan P. E.","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3003-0772","authenticated-orcid":false,"given":"David J.","family":"Chandler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,6,13]]},"reference":[{"key":"1219_CR1","doi-asserted-by":"publisher","first-page":"78","DOI":"10.3122\/jabfm.2017.01.160190","volume":"2","author":"KL Anderson","year":"2017","unstructured":"Anderson KL, Strowd LC. Epidemiology, diagnosis, and treatment of scabies in a dermatology office. J Am Board Fam Med. 2017;2:78\u201384.","journal-title":"J Am Board Fam Med"},{"key":"1219_CR2","first-page":"237","volume":"11","author":"KL Hon","year":"2012","unstructured":"Hon KL, Leung AK. Scabies in toddler twins Consult Pediatr. 2012;11:237\u20139.","journal-title":"Scabies in toddler twins. Consult Pediatr"},{"key":"1219_CR3","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1111\/j.1529-8019.2009.01243.x","volume":"22","author":"MI Hicks","year":"2009","unstructured":"Hicks MI, Elston DM. Scabies. Dermatol Ther. 2009;22:279\u201392.","journal-title":"Dermatol Ther"},{"key":"1219_CR4","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1590\/abd1806-4841.20164811","volume":"91","author":"K Ebrahim","year":"2016","unstructured":"Ebrahim K, Alves JB, Tom\u00e9 LA, et al. Norwegian scabies - Rare case of atypical manifestation. An Bras Dermatol. 2016;91:826\u20138.","journal-title":"An Bras Dermatol"},{"key":"1219_CR5","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1007\/s11908-013-0354-0","volume":"15","author":"L Shimose","year":"2013","unstructured":"Shimose L, Munoz-Price LS. Diagnosis, prevention, and treatment of scabies. Curr Infect Dis Rep. 2013;15:426\u201331.","journal-title":"Curr Infect Dis Rep"},{"key":"1219_CR6","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1093\/pch\/20.7.395","volume":"20","author":"Banerji A; Canadian Paediatric Society FNI and MHC","year":"2015","unstructured":"Banerji A; Canadian Paediatric Society FNI and MHC. Scabies. Paediatr Child Health. 2015;20:395\u2013402.","journal-title":"Paediatr Child Health"},{"key":"1219_CR7","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1111\/jcpt.12631","volume":"42","author":"J Thomas","year":"2017","unstructured":"Thomas J, Christenson JK, Walker E, Baby KE, Peterson GM. Scabies-An ancient itch that is still rampant today. J Clin Pharm Ther. 2017;42:793\u20139.","journal-title":"J Clin Pharm Ther"},{"key":"1219_CR8","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1016\/S0140-6736(99)09458-1","volume":"355","author":"O Chosidow","year":"2000","unstructured":"Chosidow O. Scabies and pediculosis. Lancet. 2000;355:819\u201326.","journal-title":"Lancet"},{"key":"1219_CR9","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1136\/bmj.2.4211.405","volume":"2","author":"K Mellanby","year":"1941","unstructured":"Mellanby K. Transmission of scabies. Br Med J. 1941;2:405\u20136.","journal-title":"Br Med J"},{"key":"1219_CR10","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1017\/S0031182000021612","volume":"35","author":"K Mellanby","year":"1944","unstructured":"Mellanby K. The development of symptoms, parasitic infection and immunity in human scabies. Parasitology. 1944;35:197\u2013206.","journal-title":"Parasitology"},{"key":"1219_CR11","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1016\/j.ijpara.2004.04.002","volume":"34","author":"SF Walton","year":"2004","unstructured":"Walton SF, Dougall A, Pizzutto S, Holt D, Taplin D, Arlian LG, et al. Genetic epidemiology of Sarcoptes scabiei (Acari: Sarcoptidae) in northern Australia. Int J Parasitol. 2004;34:839\u201349.","journal-title":"Int J Parasitol"},{"key":"1219_CR12","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1111\/ddg.13130","volume":"14","author":"C Sunderk\u00f6tter","year":"2016","unstructured":"Sunderk\u00f6tter C, Feldmeier H, F\u00f6lster-Holst R, Geisel B, Klinke-Rehbein S, Nast A, et al. S1 guidelines on the diagnosis and treatment of scabies - Short version. J Dtsch Dermatol Ges. 2016;14:1155\u201367.","journal-title":"J Dtsch Dermatol Ges"},{"key":"1219_CR13","first-page":"221","volume":"5","author":"KK Guldbakke","year":"2006","unstructured":"Guldbakke KK, Khachemoune A. Crusted scabies: a clinical review. J Drugs Dermatol. 2006;5:221\u20137.","journal-title":"J Drugs Dermatol"},{"key":"1219_CR14","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1159\/000495290","volume":"235","author":"DJ Chandler","year":"2019","unstructured":"Chandler DJ, Fuller LC. A review of scabies: an infestation more than skin deep. Dermatology. 2019;235:79\u201390. https:\/\/doi.org\/10.1159\/000495290.","journal-title":"Dermatology"},{"key":"1219_CR15","doi-asserted-by":"publisher","first-page":"2462","DOI":"10.1017\/S0950268816000443","volume":"144","author":"KE Mounsey","year":"2016","unstructured":"Mounsey KE, Murray HC, King M, Oprescu F. Retrospective analysis of institutional scabies outbreaks from 1984 to 2013: lessons learned and moving forward. Epidemiol Infect. 2016;144:2462\u201371.","journal-title":"Epidemiol Infect"},{"key":"1219_CR16","doi-asserted-by":"publisher","first-page":"1693","DOI":"10.3201\/eid2706.203681","volume":"27","author":"F Reichert","year":"2021","unstructured":"Reichert F, Schulz M, Mertens E, Lachmann R, Aebischer A. Reemergence of scabies driven by adolescents and young adults. Emerg Infect Dis. 2021;27:1693\u20136.","journal-title":"Emerg Infect Dis"},{"key":"1219_CR17","doi-asserted-by":"publisher","unstructured":"Van Deursen B; Hooiveld M; Marks S; et al. Increasing incidence of reported scabies infestations in the Netherlands, 2011\u20132021. PLoS One. 2022;17(6):e0268865. https:\/\/doi.org\/10.1371\/journal.pone.0268865.","DOI":"10.1371\/journal.pone.0268865"},{"key":"1219_CR18","doi-asserted-by":"publisher","unstructured":"Amato E, Danise LS, Groneng GM, et al. Increase of scabies infestations, Norway, 2006 to 2018. Euro Surveill. 2019;24(23):190020. https:\/\/doi.org\/10.2807\/1560-7917.ES.2019.24.23.190020.","DOI":"10.2807\/1560-7917.ES.2019.24.23.190020"},{"key":"1219_CR19","first-page":"264","volume":"59","author":"L Lugovic-Mihic","year":"2020","unstructured":"Lugovic-Mihic L, Azdajic MD, Filipovic SK, et al. An Increasing scabies incidence in Croatia: a call for coordinated action among dermatologists, physicians and epidemiologists. Zdr Varst. 2020;59:264\u201372.","journal-title":"Zdr Varst"},{"key":"1219_CR20","doi-asserted-by":"publisher","unstructured":"Redondo-Brave L, Fernandez-Martinez B, G\u00f3mez-Barroso D, et al. Scabies in Spain? A comprehensive epidemiological picture. PLoS One 2021;16:e0258780. https:\/\/doi.org\/10.1371\/journal.pone.0258780.","DOI":"10.1371\/journal.pone.0258780"},{"key":"1219_CR21","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1080\/22221751.2020.1754136","volume":"9","author":"W Zhang","year":"2020","unstructured":"Zhang W, Zhang Y, Luo L, et al. Trends in prevalence and incidence of scabies from 1990 to 2017: findings from the global burden of disease study 2017. Emerg Microbes Infect. 2020;9:813\u20136.","journal-title":"Emerg Microbes Infect"},{"key":"1219_CR22","first-page":"31","volume":"5","author":"S Lassa","year":"2011","unstructured":"Lassa S, Campbell MJ, Bennett CE. Epidemiology of scabies prevalence in the U.K. from general practice records. Br J Dermatol. 2011;5:31\u20137.","journal-title":"Br J Dermatol"},{"key":"1219_CR23","doi-asserted-by":"publisher","first-page":"1542","DOI":"10.1017\/S0950268814002143","volume":"143","author":"KA Hewitt","year":"2015","unstructured":"Hewitt KA, Nalabanda A, Cassell JA. Scabies outbreaks in residential care homes: factors associated with late recognition, burden and impact. A mixed methods study in England. Epidemiol Infect. 2015;143:1542\u201351. https:\/\/doi.org\/10.1017\/S0950268814002143.","journal-title":"Epidemiol Infect"},{"key":"1219_CR24","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1097\/QCO.0b013e328336821b","volume":"23","author":"S Bouvresse","year":"2010","unstructured":"Bouvresse S, Chosidow O. Scabies in healthcare settings. Curr Opin Infect Dis. 2010;23:111\u20138.","journal-title":"Curr Opin Infect Dis"},{"key":"1219_CR25","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1007\/s13555-019-00325-2","volume":"9","author":"J Raffi","year":"2019","unstructured":"Raffi J, Suresh R, Butler DC. Review of scabies in older adults. Dermatol Ther (Heidelb). 2019;9:623\u201330. https:\/\/doi.org\/10.1007\/s13555-019-00325-2.","journal-title":"Dermatol Ther (Heidelb)"},{"key":"1219_CR26","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1016\/S1473-3099(18)30347-5","volume":"18","author":"JA Cassell","year":"2018","unstructured":"Cassell JA, Middleton J, Nalabanda A, et al. Scabies outbreaks in ten care homes for older people: a prospective study of clinical features, epidemiology, and treatment outcomes. Lancet Infect Dis. 2018;18:894\u2013902.","journal-title":"Lancet Infect Dis"},{"key":"1219_CR27","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1136\/pgmj.2003.014563","volume":"80","author":"JS McCarthy","year":"2004","unstructured":"McCarthy JS, Kemp DJ, Walton SF, Currie BJ. Scabies: more than just an irritation. Postgrad Med J. 2004;80:382\u20137. https:\/\/doi.org\/10.1136\/pgmj.2003.014563.","journal-title":"Postgrad Med J"},{"key":"1219_CR28","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1016\/S1473-3099(18)30347-5","volume":"18","author":"JA Cassell","year":"2018","unstructured":"Cassell JA, Middleton J, Nalabanda A, Lanza S, Head MG, Bostock J, et al. Scabies outbreaks in ten care homes for older people: a prospective study of clinical features, epidemiology, and treatment outcomes. Lancet Infect Dis. 2018;18:894\u2013902. https:\/\/doi.org\/10.1016\/S1473-3099(18)30347-5.","journal-title":"Lancet Infect Dis"},{"key":"1219_CR29","first-page":"455","volume":"231","author":"AD Deshpande","year":"1987","unstructured":"Deshpande AD. Eosinophilia associated with scabies. Practitioner. 1987;231:455.","journal-title":"Practitioner"},{"key":"1219_CR30","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1001\/archderm.143.5.670-b","volume":"143","author":"JC Sluzevich","year":"2007","unstructured":"Sluzevich JC, Sheth AP, Lucky AW. Persistent eosinophilia as a presenting sign of scabies in patients with disorders of keratinization. Arch Dermatol. 2007;143:670\u20133. https:\/\/doi.org\/10.1001\/archderm.143.5.670-b.","journal-title":"Arch Dermatol"},{"key":"1219_CR31","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1603\/0022-2585-41.1.74","volume":"41","author":"LG Arlian","year":"2004","unstructured":"Arlian LG, Morgan MS, Estes SA, Walton SF, Kemp DJ, Currie BJ. Circulating IgE in patients with ordinary and crusted scabies. J Med Entomol. 2004;41:74\u20137. https:\/\/doi.org\/10.1603\/0022-2585-41.1.74.","journal-title":"J Med Entomol"},{"key":"1219_CR32","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.jinf.2004.08.033","volume":"50","author":"LJ Roberts","year":"2005","unstructured":"Roberts LJ, Huffam SE, Walton SF, Currie BJ. Crusted scabies: clinical and immunological findings in seventy-eight patients and a review of the literature. J Infect. 2005;50:375\u201381. https:\/\/doi.org\/10.1016\/j.jinf.2004.08.033.","journal-title":"J Infect"},{"key":"1219_CR33","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.sder.2011.04.002","volume":"30","author":"TG Berger","year":"2011","unstructured":"Berger TG, Steinhoff M. Pruritus in older patients\u2013Eruptions of senescence. Semin Cutan Med Surg. 2011;30:113\u20137. https:\/\/doi.org\/10.1016\/j.sder.2011.04.002.","journal-title":"Semin Cutan Med Surg"},{"key":"1219_CR34","doi-asserted-by":"publisher","first-page":"78","DOI":"10.3122\/jabfm.2017.01.160190","volume":"30","author":"KL Anderson","year":"2017","unstructured":"Anderson KL, Strowd LC. Epidemiology, diagnosis, and treatment of scabies in a dermatology office. J Am Board Fam Med. 2017;30:78\u201384. https:\/\/doi.org\/10.3122\/jabfm.2017.01.160190.","journal-title":"J Am Board Fam Med"},{"key":"1219_CR35","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1111\/j.1365-2133.2005.06591.x","volume":"153","author":"J Heukelbach","year":"2005","unstructured":"Heukelbach J, Wilcke T, Winter B, Feldmeier H. Epidemiology and morbidity of scabies and pediculosis capitis in resource-poor communities in Brazil. Br J Dermatol. 2005;153:150\u20136. https:\/\/doi.org\/10.1111\/j.1365-2133.2005.06591.x.","journal-title":"Br J Dermatol"},{"key":"1219_CR36","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1111\/bjd.18943","volume":"183","author":"D Engelman","year":"2020","unstructured":"Engelman D, Yoshizumi J, Hay RJ, Osti M, Micali G, Norton S, et al. The 2020 International Alliance for the Control of Scabies consensus criteria for the diagnosis of scabies. Br J Dermatol. 2020;183:808\u201320. https:\/\/doi.org\/10.1111\/bjd.18943.","journal-title":"Br J Dermatol"},{"key":"1219_CR37","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1111\/ced.15118","volume":"47","author":"D Chandler","year":"2022","unstructured":"Chandler D. Direct microscopy in the dermatology clinic: enhancing the management of skin infections and infestations. Clin Exp Dermatol. 2022;47:1023\u20139.","journal-title":"Clin Exp Dermatol"},{"key":"1219_CR38","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1016\/j.ijwd.2020.08.003","volume":"6","author":"M Braun","year":"2020","unstructured":"Braun M, Yedidi RS, Raffi J, Butler DC, Murase JE. The challenge of diagnosing scabies in older adults: a case and a novel therapeutic approach. Int J Womens Dermatol. 2020;6:452\u20133. https:\/\/doi.org\/10.1016\/j.ijwd.2020.08.003.","journal-title":"Int J Womens Dermatol"},{"key":"1219_CR39","doi-asserted-by":"publisher","first-page":"1718","DOI":"10.1056\/NEJMcp052784","volume":"354","author":"O Chosidow","year":"2006","unstructured":"Chosidow O. Clinical practices. Scabies N Engl J Med. 2006;354:1718\u201327. https:\/\/doi.org\/10.1056\/NEJMcp052784.","journal-title":"Scabies. N Engl J Med"},{"key":"1219_CR40","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1155\/2011\/698494","volume":"22","author":"V Leung","year":"2011","unstructured":"Leung V, Miller M. Detection of scabies: a systematic review of diagnostic methods. Can J Infect Dis Med Microbiol. 2011;22:143\u20136.","journal-title":"Can J Infect Dis Med Microbiol"},{"key":"1219_CR41","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2020-240507","volume":"14","author":"M Lupu","year":"2021","unstructured":"Lupu M, Voiculescu V, Vajaitu C, et al. In vivo reflectance confocal microscopy for the diagnosis of scabies. BMJ Case Rep. 2021;14: e240507. https:\/\/doi.org\/10.1136\/bcr-2020-240507.","journal-title":"BMJ Case Rep"},{"key":"1219_CR42","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1159\/000352066","volume":"5","author":"CA Banzhaf","year":"2013","unstructured":"Banzhaf CA, Themstrup L, Ring HC, et al. In vivo imaging of Sarcoptes scabiei infestation using optical coherence tomography. Case Rep Dermatol. 2013;5:156\u201362.","journal-title":"Case Rep Dermatol"},{"key":"1219_CR43","doi-asserted-by":"publisher","first-page":"1758","DOI":"10.1093\/ced\/llae358","volume":"49","author":"DMW Balak","year":"2024","unstructured":"Balak DMW, Rauwerdink D. Diagnosing scabies in a patient with skin of colour using the burrow ink test. Clin Exp Dermatol. 2024;49:1758\u20139.","journal-title":"Clin Exp Dermatol"},{"key":"1219_CR44","first-page":"197","volume":"182","author":"P Delaunay","year":"2020","unstructured":"Delaunay P, H\u00e9riss\u00e9 AL, Hasseine L, Chiaverini C, Tran A, Mary C, et al. Scabies polymerase chain reaction with standardized dry swab sampling: an easy tool for cluster diagnosis of human scabies. Br J Dermatol. 2020;182:197\u2013201.","journal-title":"Br J Dermatol"},{"key":"1219_CR45","unstructured":"NICE. Scabies: What else might it be? 2024. https:\/\/cks.nice.org.uk\/topics\/scabies\/diagnosis\/differential-diagnosis\/. Accessed 22\/4\/25."},{"key":"1219_CR46","doi-asserted-by":"publisher","first-page":"3121","DOI":"10.1017\/S0950268816001746","volume":"144","author":"LCJ White","year":"2016","unstructured":"White LCJ, Lanza S, Middleton J, Hewitt K, Freire-Moran L, Edge C, et al. The management of scabies outbreaks in residential care facilities for older adults in England: a review of current health protection guidelines. Epidemiol Infect. 2016;144:3121\u201330. https:\/\/doi.org\/10.1017\/S0950268816001746.","journal-title":"Epidemiol Infect"},{"key":"1219_CR47","doi-asserted-by":"publisher","first-page":"1542","DOI":"10.1017\/S0950268814002143","volume":"143","author":"KA Hewitt","year":"2015","unstructured":"Hewitt KA, Nalabanda A, Cassell JA. Scabies outbreaks in residential care homes: factors associated with late recognition, burden and impact. A mixed methods study in England. Epidemiol Infect. 2015;143:1542\u201351. https:\/\/doi.org\/10.1017\/S0950268814002143.","journal-title":"Epidemiol Infect"},{"key":"1219_CR48","doi-asserted-by":"publisher","first-page":"2462","DOI":"10.1017\/S0950268816000443","volume":"144","author":"KE Mounsey","year":"2016","unstructured":"Mounsey KE, Murray HC, King M, Oprescu F. Retrospective analysis of institutional scabies outbreaks from 1984 to 2013: lessons learned and moving forward. Epidemiol Infect. 2016;144:2462\u201371. https:\/\/doi.org\/10.1017\/S0950268816000443.","journal-title":"Epidemiol Infect"},{"key":"1219_CR49","unstructured":"NICE CKS. Scenario: management of scabies. 2024. https:\/\/cks.nice.org.uk\/topics\/scabies\/management\/management-of-scabies\/."},{"key":"1219_CR50","unstructured":"World Health Organisation. Scabies 2023. https:\/\/www.who.int\/newsroom\/fact-sheets\/detail\/scabies. Accessed 22\/4\/25."},{"key":"1219_CR51","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1093\/bjd\/ljad501","volume":"190","author":"D Meyersburg","year":"2023","unstructured":"Meyersburg D, Hoellwerth M, Brandlmaier M, et al. Comparison of topical permethrin 5% vs. benzyl benzoate 25% treatment in scabies: a double-blinded randomized controlled trial. Br J Dermatol. 2023;190:486\u201391. https:\/\/doi.org\/10.1093\/bjd\/ljad501.","journal-title":"Br J Dermatol"},{"key":"1219_CR52","unstructured":"NICE. Difficult to treat scabies: oral. 2014. https:\/\/www.NiceOrgUk\/Advice\/Esuom29\/Resources\/Difficulttotreat-Scabies-Oral-Ivermectin-Pdf-54116459009974213."},{"key":"1219_CR53","doi-asserted-by":"publisher","unstructured":"Welch E, Romani L, Whitfield MJ. Recent advances in understanding and treating scabies. Fac Rev 2021;10:28. https:\/\/doi.org\/10.12703\/r\/10-28.","DOI":"10.12703\/r\/10-28"},{"key":"1219_CR54","unstructured":"South West London Joint Medicines Forumlary. Infections. n.d. https:\/\/www.SwljointmedicinesformularyNhsUk\/ChaptersSubDetailsAsp?FormularySectionID=5&SubSectionRef=050501&SubSectionID=A100&drugmatch=5380#TLDEFS."},{"key":"1219_CR55","doi-asserted-by":"publisher","first-page":"2068","DOI":"10.1016\/S0140-6736(19)32619-4","volume":"394","author":"J Middleton","year":"2019","unstructured":"Middleton J, Walker SL, House T, et al. Ivermectin for the control of scabies outbreaks in the UK. Lancet. 2019;394:2068\u20139.","journal-title":"Lancet"},{"key":"1219_CR56","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004389","volume":"10","author":"KE Mounsey","year":"2016","unstructured":"Mounsey KE, Bernigaud C, Chosidow O, McCarthy JS. Prospects for moxidectin as a new oral treatment for human scabies. PLoS Negl Trop Dis. 2016;10: e0004389. https:\/\/doi.org\/10.1371\/journal.pntd.0004389.","journal-title":"PLoS Negl Trop Dis"},{"key":"1219_CR57","doi-asserted-by":"publisher","unstructured":"Berniqaud C, Fang F, Fischer L; et al. Preclinical study of single-dose moxidectin, a new oral treatment for scabies: efficacy, safety, and pharmacokinetics compared to two-dose ivermectin in a porcine model. PLoS Negl Trop Dis. 2016;10(10):e0005030. https:\/\/doi.org\/10.1371\/journal.pntd.0005030.","DOI":"10.1371\/journal.pntd.0005030"},{"key":"1219_CR58","unstructured":"National Library of Medicine. Spinosad. PubChem n.d. https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Spinosad. Accessed 22\/4\/25."},{"key":"1219_CR59","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1080\/14787210.2022.2099376","volume":"9","author":"DFK Fernando","year":"2022","unstructured":"Fernando DFK. Spinosad topical suspension (0.9%): a new topical treatment for scabies. Expert Rev Anti Infect Ther. 2022;9:1149\u201354.","journal-title":"Expert Rev Anti Infect Ther"},{"key":"1219_CR60","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/j.ijid.2020.09.554","volume":"101","author":"AT Utami","year":"2020","unstructured":"Utami AT, Mafaz Z, Perdana NRG, Assegaf AAR. Novel therapy of scabies\u2019s disease. Int J Infect Dis. 2020;101:208. https:\/\/doi.org\/10.1016\/j.ijid.2020.09.554.","journal-title":"Int J Infect Dis"},{"key":"1219_CR61","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1007\/s13555-019-00325-2","volume":"9","author":"J Raffi","year":"2019","unstructured":"Raffi J, Suresh R, Butler DC. Review of scabies in older adults. Dermatol Ther (Heidelb). 2019;9:623\u201330.","journal-title":"Dermatol Ther (Heidelb)"},{"key":"1219_CR62","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.jhin.2006.08.012","volume":"65","author":"R Vorou","year":"2007","unstructured":"Vorou R, Remoudaki HD, Maltezou HC. Nosocomial scabies. J Hosp Infect. 2007;65:9\u201314.","journal-title":"J Hosp Infect"},{"key":"1219_CR63","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1111\/1523-1747.ep12532761","volume":"73","author":"W Montagna","year":"1979","unstructured":"Montagna W, Carlisle K. Structural changes in aging human skin. J Invest Dermatol. 1979;73:47\u201353.","journal-title":"J Invest Dermatol"},{"key":"1219_CR64","unstructured":"British Association of Dermatologists. Management of Scabies in the UK. 2023. Retrieved from BadOrgUk: https:\/\/CdnBadOrgUk\/Uploads\/2023\/10\/Scabies-Guidance-OCT-2023Pdf. Accessed 22 Apr 2025."},{"key":"1219_CR65","unstructured":"UK Health Security Agency. UKHSA guidance on the management of scabies cases and outbreaks in long-term care facilities and other closed settings. 2024. https:\/\/www.GovUk\/Government\/Publications\/Scabies-Management-Advice-for-Health-Professionals\/Ukhsa-Guidance-on-the-Management-of-Scabies-Cases-and-Outbreaks-in-Long-Term-Care-Facilities-and-Other-Closed-Settings. Accessed 22 Apr 2025."}],"container-title":["Drugs &amp; Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40266-025-01219-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40266-025-01219-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40266-025-01219-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T19:26:07Z","timestamp":1757186767000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40266-025-01219-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,13]]},"references-count":65,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["1219"],"URL":"https:\/\/doi.org\/10.1007\/s40266-025-01219-z","relation":{},"ISSN":["1170-229X","1179-1969"],"issn-type":[{"value":"1170-229X","type":"print"},{"value":"1179-1969","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,13]]},"assertion":[{"value":"27 May 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 June 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding Sources"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"Data sharing is not applicable to this article as no new data were created or analysed in this study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Data Availability:"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Statement"}},{"value":"Not applicable.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"Not applicable.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code Availability"}},{"value":"V.K., C.V. and J.W. contributed equally to the writing of the original draft, and D.C. was responsible for reviewing and editing the manuscript.","order":9,"name":"Ethics","group":{"name":"EthicsHeading","label":"Author Contributions"}}]}}