{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:44:34Z","timestamp":1777391074696,"version":"3.51.4"},"reference-count":263,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T00:00:00Z","timestamp":1758672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T00:00:00Z","timestamp":1758672000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Drugs Aging"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1007\/s40266-025-01246-w","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T13:36:21Z","timestamp":1758720981000},"page":"1011-1043","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Anesthesia Considerations in Older Adults Undergoing Emergency Mechanical Thrombectomy for Acute Ischaemic Stroke"],"prefix":"10.1007","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6468-6879","authenticated-orcid":false,"given":"Byrappa","family":"Vinay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nitin","family":"Manohara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Jain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,9,24]]},"reference":[{"issue":"17","key":"1246_CR1","doi-asserted-by":"publisher","first-page":"11177","DOI":"10.15766\/mep_2374-8265.11177","volume":"23","author":"S Bentley","year":"2021","unstructured":"Bentley S, Feldman N, Boehm L, Zavala M, Dilos B, McIndoe M, et al. Stroke code from EMS to thrombectomy: an interdisciplinary in situ simulation for prompt management of acute ischemic stroke. MedEdPORTAL. 2021;23(17):11177. https:\/\/doi.org\/10.15766\/mep_2374-8265.11177.","journal-title":"MedEdPORTAL."},{"issue":"10","key":"1246_CR2","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.3389\/fneur.2019.01355","volume":"24","author":"W Zhao","year":"2020","unstructured":"Zhao W, Ma P, Zhang P, Yue X. Mechanical Thrombectomy for acute ischemic stroke in octogenarians: a systematic review and meta-analysis. Front Neurol. 2020;24(10):1355. https:\/\/doi.org\/10.3389\/fneur.2019.01355.","journal-title":"Front Neurol"},{"issue":"6","key":"1246_CR3","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1111\/j.1468-1331.2006.01138.x","volume":"13","author":"T Truelsen","year":"2006","unstructured":"Truelsen T, Piechowski-J\u00f3\u017awiak B, Bonita R, Mathers C, Bogousslavsky J, Boysen G. Stroke incidence and prevalence in Europe: a review of available data. Eur J Neurol. 2006;13(6):581\u201398. https:\/\/doi.org\/10.1111\/j.1468-1331.2006.01138.x.","journal-title":"Eur J Neurol"},{"issue":"1","key":"1246_CR4","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1093\/ageing\/afm134","volume":"37","author":"KD Palnum","year":"2008","unstructured":"Palnum KD, Petersen P, S\u00f8rensen HT, Ingeman A, Mainz J, Bartels P, et al. Older patients with acute stroke in Denmark: quality of care and short-term mortality A nationwide follow-up study. Age Ageing. 2008;37(1):90\u20135. https:\/\/doi.org\/10.1093\/ageing\/afm134.","journal-title":"Age Ageing"},{"key":"1246_CR5","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/B978-0-323-98804-9.00030-X","volume-title":"Beauty, aging, and anti aging","author":"S Debba\u011f","year":"2023","unstructured":"Debba\u011f S, \u00dcst\u00fcn GG. Anesthesia for the elderly: Effects of aging on perioperative and postoperative care. In: Vargel \u0130, \u00d6zg\u00fcr FF, editors. Beauty, aging, and anti aging. Academic Press; 2023. p. 429\u201338. https:\/\/doi.org\/10.1016\/B978-0-323-98804-9.00030-X."},{"issue":"10","key":"1246_CR6","doi-asserted-by":"publisher","first-page":"1128","DOI":"10.23736\/S0375-9393.21.15388-X","volume":"87","author":"C Olotu","year":"2021","unstructured":"Olotu C. Anesthesia for the elderly: a narrative review. Minerva Anestesiol. 2021;87(10):1128\u201338. https:\/\/doi.org\/10.23736\/S0375-9393.21.15388-X.","journal-title":"Minerva Anestesiol"},{"issue":"2","key":"1246_CR7","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1002\/clc.23313","volume":"43","author":"NSV Singam","year":"2020","unstructured":"Singam NSV, Fine C, Fleg JL. Cardiac changes associated with vascular aging. Clin Cardiol. 2020;43(2):92\u20138. https:\/\/doi.org\/10.1002\/clc.23313.","journal-title":"Clin Cardiol"},{"issue":"2018","key":"1246_CR8","doi-asserted-by":"publisher","first-page":"7156435","DOI":"10.1155\/2018\/7156435","volume":"10","author":"JO Fajemiroye","year":"2018","unstructured":"Fajemiroye JO, da Cunha LC, Saavedra-Rodr\u00edguez R, et al. Aging-induced biological changes and cardiovascular diseases. Biomed Res Int. 2018;10(2018):7156435. https:\/\/doi.org\/10.1155\/2018\/7156435.","journal-title":"Biomed Res Int"},{"issue":"1","key":"1246_CR9","first-page":"59","volume":"89","author":"S O'Callaghan","year":"2016","unstructured":"O\u2019Callaghan S, Kenny RA. Neurocardiovascular instability and cognition. Yale J Biol Med. 2016;89(1):59\u201371.","journal-title":"Yale J Biol Med"},{"issue":"4","key":"1246_CR10","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1016\/s1053-0770(03)00161-7","volume":"17","author":"GA Rooke","year":"2003","unstructured":"Rooke GA. Cardiovascular aging and anesthetic implications. J Cardiothorac Vasc Anesth. 2003;17(4):512\u201323. https:\/\/doi.org\/10.1016\/s1053-0770(03)00161-7.","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"6","key":"1246_CR11","first-page":"637","volume":"77","author":"G Bettelli","year":"2011","unstructured":"Bettelli G. Preoperative evaluation in geriatric surgery: comorbidity, functional status and pharmacological history. Minerva Anestesiol. 2011;77(6):637\u201346 (PMID: 21617627).","journal-title":"Minerva Anestesiol"},{"issue":"1","key":"1246_CR12","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1034\/j.1399-3003.1999.13a36.x","volume":"13","author":"JP Janssens","year":"1999","unstructured":"Janssens JP, Pache JC, Nicod LP. Physiological changes in respiratory function associated with ageing. Eur Respir J. 1999;13(1):197\u2013205. https:\/\/doi.org\/10.1034\/j.1399-3003.1999.13a36.x.","journal-title":"Eur Respir J"},{"issue":"4","key":"1246_CR13","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.cger.2017.06.001","volume":"33","author":"GS Skloot","year":"2017","unstructured":"Skloot GS. The effects of aging on lung structure and function. Clin Geriatr Med. 2017;33(4):447\u201357. https:\/\/doi.org\/10.1016\/j.cger.2017.06.001.","journal-title":"Clin Geriatr Med"},{"issue":"3","key":"1246_CR14","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1001\/archinte.163.3.356","volume":"163","author":"PJ Swedko","year":"2003","unstructured":"Swedko PJ, Clark HD, Paramsothy K, Akbari A. Serum creatinine is an inadequate screening test for renal failure in elderly patients. Arch Intern Med. 2003;163(3):356\u201360. https:\/\/doi.org\/10.1001\/archinte.163.3.356.","journal-title":"Arch Intern Med"},{"issue":"3","key":"1246_CR15","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.anclin.2015.05.003","volume":"33","author":"BD Alvis","year":"2015","unstructured":"Alvis BD, Hughes CG. Physiology considerations in geriatric patients. Anesthesiol Clin. 2015;33(3):447\u201356. https:\/\/doi.org\/10.1016\/j.anclin.2015.05.003.","journal-title":"Anesthesiol Clin"},{"issue":"12","key":"1246_CR16","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1007\/s40266-024-01161-6","volume":"41","author":"E Ahrens","year":"2024","unstructured":"Ahrens E, Wachtendorf LJ, Hill KP, Schaefer MS. Considerations for anesthesia in older adults with cannabis use. Drugs Aging. 2024;41(12):933\u201343. https:\/\/doi.org\/10.1007\/s40266-024-01161-6.","journal-title":"Drugs Aging"},{"issue":"1","key":"1246_CR17","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1053\/j.ackd.2015.08.004","volume":"23","author":"A Denic","year":"2016","unstructured":"Denic A, Glassock RJ, Rule AD. Structural and functional changes with the aging kidney. Adv Chronic Kidney Dis. 2016;23(1):19\u201328. https:\/\/doi.org\/10.1053\/j.ackd.2015.08.004.","journal-title":"Adv Chronic Kidney Dis"},{"issue":"4","key":"1246_CR18","doi-asserted-by":"publisher","first-page":"474","DOI":"10.4103\/sja.sja_579_23","volume":"17","author":"E Luca","year":"2023","unstructured":"Luca E, Schipa C, Cambise C, Sollazzi L, Aceto P. Implication of age-related changes on anesthesia management. Saudi J Anaesth. 2023;17(4):474\u201381. https:\/\/doi.org\/10.4103\/sja.sja_579_23.","journal-title":"Saudi J Anaesth"},{"issue":"1","key":"1246_CR19","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1046\/j.1365-2125.2003.02007.x","volume":"57","author":"AA Mangoni","year":"2004","unstructured":"Mangoni AA, Jackson SH. Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications. Br J Clin Pharmacol. 2004;57(1):6\u201314. https:\/\/doi.org\/10.1046\/j.1365-2125.2003.02007.x.","journal-title":"Br J Clin Pharmacol"},{"issue":"1","key":"1246_CR20","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1097\/ACO.0000000000000544","volume":"31","author":"S Akhtar","year":"2018","unstructured":"Akhtar S. Pharmacological considerations in the elderly. Curr Opin Anaesthesiol. 2018;31(1):11\u20138. https:\/\/doi.org\/10.1097\/ACO.0000000000000544.","journal-title":"Curr Opin Anaesthesiol"},{"issue":"2","key":"1246_CR21","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1177\/2151458510394606","volume":"2","author":"R Yang","year":"2011","unstructured":"Yang R, Wolfson M, Lewis MC. Unique aspects of the elderly surgical population: an anesthesiologist\u2019s perspective. Geriatr Orthop Surg Rehabil. 2011;2(2):56\u201364. https:\/\/doi.org\/10.1177\/2151458510394606.","journal-title":"Geriatr Orthop Surg Rehabil."},{"issue":"2","key":"1246_CR22","doi-asserted-by":"publisher","first-page":"116","DOI":"10.2174\/1874609809666151124233206","volume":"9","author":"PK Mandal","year":"2016","unstructured":"Mandal PK, Saharan S, Penna O, Fodale V. Anesthesia issues in central nervous system disorders. Curr Aging Sci. 2016;9(2):116\u201343. https:\/\/doi.org\/10.2174\/1874609809666151124233206.","journal-title":"Curr Aging Sci"},{"key":"1246_CR23","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/bs.vh.2020.12.010","volume":"115","author":"MA Kurauti","year":"2021","unstructured":"Kurauti MA, Soares GM, Marmentini C, Bronczek GA, Branco RCS, Boschero AC. Insulin and aging. Vitam Horm. 2021;115:185\u2013219. https:\/\/doi.org\/10.1016\/bs.vh.2020.12.010.","journal-title":"Vitam Horm"},{"key":"1246_CR24","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1146\/annurev.physiol.67.040403.120816","volume":"67","author":"E Charmandari","year":"2005","unstructured":"Charmandari E, Tsigos C, Chrousos G. Endocrinology of the stress response. Annu Rev Physiol. 2005;67:259\u201384. https:\/\/doi.org\/10.1146\/annurev.physiol.67.040403.120816.","journal-title":"Annu Rev Physiol"},{"issue":"4","key":"1246_CR25","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/j.pmr.2017.06.004","volume":"28","author":"WR Frontera","year":"2017","unstructured":"Frontera WR. Physiologic changes of the musculoskeletal system with aging: a brief review. Phys Med Rehabil Clin N Am. 2017;28(4):705\u201311. https:\/\/doi.org\/10.1016\/j.pmr.2017.06.004.","journal-title":"Phys Med Rehabil Clin N Am"},{"issue":"1","key":"1246_CR26","doi-asserted-by":"publisher","first-page":"152","DOI":"10.4103\/ija.ija_1029_22","volume":"67","author":"A Mahender","year":"2023","unstructured":"Mahender A, Chavan SS, Saroa R, Chauhan M. Recent advances in geriatric anaesthesia. Indian J Anaesth. 2023;67(1):152\u20138. https:\/\/doi.org\/10.4103\/ija.ija_1029_22.","journal-title":"Indian J Anaesth"},{"issue":"3","key":"1246_CR27","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1016\/j.anclin.2015.05.004","volume":"33","author":"S Akhtar","year":"2015","unstructured":"Akhtar S, Ramani R. Geriatric pharmacology. Anesthesiol Clin. 2015;33(3):457\u201369. https:\/\/doi.org\/10.1016\/j.anclin.2015.05.004.","journal-title":"Anesthesiol Clin"},{"key":"1246_CR28","doi-asserted-by":"publisher","unstructured":"Ngcobo NN. Influence of ageing on the pharmacodynamics and pharmacokinetics of chronically administered medicines in geriatric patients: a review. Clin Pharmacokinet. 2025;64(3):335\u201367. https:\/\/doi.org\/10.1007\/s40262-024-01466-0. Erratum in: Clin Pharmacokinet. 2025;64(3):463. https:\/\/doi.org\/10.1007\/s40262-025-01494-4.","DOI":"10.1007\/s40262-024-01466-0"},{"issue":"1","key":"1246_CR29","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1097\/ACO.0000000000000814","volume":"33","author":"PA Th\u00fcrmann","year":"2020","unstructured":"Th\u00fcrmann PA. Pharmacodynamics and pharmacokinetics in older adults. Curr Opin Anaesthesiol. 2020;33(1):109\u201313. https:\/\/doi.org\/10.1097\/ACO.0000000000000814.","journal-title":"Curr Opin Anaesthesiol"},{"key":"1246_CR30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2022.110846","volume":"80","author":"RB Schonberger","year":"2022","unstructured":"Schonberger RB, Dai F, Michel G, Vaughn MT, Burg MM, Mathis M, et al. Association of propofol induction dose and severe pre-incision hypotension among surgical patients over age 65. J Clin Anesth. 2022;80:110846. https:\/\/doi.org\/10.1016\/j.jclinane.2022.110846.","journal-title":"J Clin Anesth"},{"issue":"11","key":"1246_CR31","first-page":"1201","volume":"81","author":"P Aceto","year":"2015","unstructured":"Aceto P, Perilli V, Lai C, Sacco T, Modesti C, Luca E, et al. Minimum alveolar concentration threshold of sevoflurane for postoperative dream recall. Minerva Anestesiol. 2015;81(11):1201\u20139 (Epub 2014 Dec 23 PMID: 25532493).","journal-title":"Minerva Anestesiol"},{"key":"1246_CR32","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajp.2024.104132","volume":"99","author":"GB Zhang","year":"2024","unstructured":"Zhang GB, Li HY, Yu WJ, Ying YZ, Zheng D, Zhang XK, et al. Occurrence and risk factors for post-stroke delirium: a systematic review and meta-analysis. Asian J Psychiatr. 2024;99:104132. https:\/\/doi.org\/10.1016\/j.ajp.2024.104132.","journal-title":"Asian J Psychiatr"},{"issue":"17","key":"1246_CR33","doi-asserted-by":"publisher","first-page":"1486726","DOI":"10.3389\/fnagi.2025.1486726","volume":"14","author":"M Hahn","year":"2025","unstructured":"Hahn M, Brockstedt L, Gr\u00f6schel S, et al. Delirium following mechanical thrombectomy for ischemic stroke - individuals at risk, imaging biomarkers and prognosis. Front Aging Neurosci. 2025;14(17):1486726. https:\/\/doi.org\/10.3389\/fnagi.2025.1486726.","journal-title":"Front Aging Neurosci."},{"issue":"Suppl 1","key":"1246_CR34","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1111\/anae.15607","volume":"77","author":"CJ Swarbrick","year":"2022","unstructured":"Swarbrick CJ, Partridge JSL. Evidence-based strategies to reduce the incidence of postoperative delirium: a narrative review. Anaesthesia. 2022;77(Suppl 1):92\u2013101. https:\/\/doi.org\/10.1111\/anae.15607.","journal-title":"Anaesthesia"},{"key":"1246_CR35","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.jclinane.2019.06.028","volume":"59","author":"Y Cui","year":"2020","unstructured":"Cui Y, Li G, Cao R, Luan L, Kla KM. The effect of perioperative anesthetics for prevention of postoperative delirium on general anesthesia: a network meta-analysis. J Clin Anesth. 2020;59:89\u201398. https:\/\/doi.org\/10.1016\/j.jclinane.2019.06.028.","journal-title":"J Clin Anesth"},{"issue":"4","key":"1246_CR36","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1016\/j.bja.2020.06.063","volume":"125","author":"Z Jin","year":"2020","unstructured":"Jin Z, Hu J, Ma D. Postoperative delirium: perioperative assessment, risk reduction, and management. Br J Anaesth. 2020;125(4):492\u2013504. https:\/\/doi.org\/10.1016\/j.bja.2020.06.063.","journal-title":"Br J Anaesth"},{"issue":"1","key":"1246_CR37","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1093\/gerona\/58.1.m76","volume":"58","author":"RS Morrison","year":"2003","unstructured":"Morrison RS, Magaziner J, Gilbert M, Koval KJ, McLaughlin MA, Orosz G, et al. Relationship between pain and opioid analgesics on the development of delirium following hip fracture. J Gerontol A Biol Sci Med Sci. 2003;58(1):76\u201381. https:\/\/doi.org\/10.1093\/gerona\/58.1.m76.","journal-title":"J Gerontol A Biol Sci Med Sci"},{"issue":"3","key":"1246_CR38","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1097\/ALN.0b013e318164ca81","volume":"108","author":"S Dahmani","year":"2008","unstructured":"Dahmani S, Paris A, Jannier V, Hein L, Rouelle D, Scholz J, et al. Dexmedetomidine increases hippocampal phosphorylated extracellular signal-regulated protein kinase 1 and 2 content by an alpha 2-adrenoceptor-independent mechanism: evidence for the involvement of imidazoline I1 receptors. Anesthesiology. 2008;108(3):457\u201366. https:\/\/doi.org\/10.1097\/ALN.0b013e318164ca81.","journal-title":"Anesthesiology"},{"issue":"4","key":"1246_CR39","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1093\/bja\/aex257","volume":"119","author":"P Guldenmund","year":"2017","unstructured":"Guldenmund P, Vanhaudenhuyse A, Sanders RD, Sleigh J, Bruno MA, Demertzi A, et al. Brain functional connectivity differentiates dexmedetomidine from propofol and natural sleep. Br J Anaesth. 2017;119(4):674\u201384. https:\/\/doi.org\/10.1093\/bja\/aex257.","journal-title":"Br J Anaesth"},{"issue":"10","key":"1246_CR40","doi-asserted-by":"publisher","first-page":"1342","DOI":"10.1111\/anae.15469","volume":"76","author":"J van Norden","year":"2021","unstructured":"van Norden J, Spies CD, Borchers F, Mertens M, Kurth J, Heidgen J, et al. The effect of peri-operative dexmedetomidine on the incidence of postoperative delirium in cardiac and non-cardiac surgical patients: a randomised, double-blind placebo-controlled trial. Anaesthesia. 2021;76(10):1342\u201351. https:\/\/doi.org\/10.1111\/anae.15469.","journal-title":"Anaesthesia"},{"issue":"5","key":"1246_CR41","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1016\/j.bja.2021.07.021","volume":"127","author":"LA Evered","year":"2021","unstructured":"Evered LA, Chan MTV, Han R, Chu MHM, Cheng BP, Scott DA, et al. Anaesthetic depth and delirium after major surgery: a randomised clinical trial. Br J Anaesth. 2021;127(5):704\u201312. https:\/\/doi.org\/10.1016\/j.bja.2021.07.021.","journal-title":"Br J Anaesth"},{"issue":"11","key":"1246_CR42","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1007\/s40266-016-0413-y","volume":"33","author":"C Str\u00f8m","year":"2016","unstructured":"Str\u00f8m C, Rasmussen LS, Steinmetz J. Practical management of anaesthesia in the elderly. Drugs Aging. 2016;33(11):765\u201377. https:\/\/doi.org\/10.1007\/s40266-016-0413-y.","journal-title":"Drugs Aging"},{"issue":"17","key":"1246_CR43","doi-asserted-by":"publisher","first-page":"509","DOI":"10.2147\/CIA.S358633","volume":"16","author":"L Adem","year":"2022","unstructured":"Adem L, Tegegne GT. Medication appropriateness, polypharmacy, and drug-drug interactions in ambulatory elderly patients with cardiovascular diseases at Tikur Anbessa Specialized Hospital. Ethiopia Clin Interv Aging. 2022;16(17):509\u201317. https:\/\/doi.org\/10.2147\/CIA.S358633.","journal-title":"Ethiopia. Clin Interv Aging."},{"issue":"7","key":"1246_CR44","doi-asserted-by":"publisher","first-page":"509","DOI":"10.2165\/11592010-000000000-00000","volume":"28","author":"G Sergi","year":"2011","unstructured":"Sergi G, De Rui M, Sarti S, Manzato E. Polypharmacy in the elderly: can comprehensive geriatric assessment reduce inappropriate medication use? Drugs Aging. 2011;28(7):509\u201318. https:\/\/doi.org\/10.2165\/11592010-000000000-00000.","journal-title":"Drugs Aging"},{"key":"1246_CR45","doi-asserted-by":"publisher","first-page":"51","DOI":"10.2165\/00023210-199708010-00005","volume":"8","author":"M Naguib","year":"1997","unstructured":"Naguib M, Magboul MMA, Jaroudi R. Clinically significant drug interactions with general anaesthetics. CNS Drugs. 1997;8:51\u201378.","journal-title":"CNS Drugs"},{"issue":"10","key":"1246_CR46","doi-asserted-by":"publisher","first-page":"2010","DOI":"10.1111\/cts.13608","volume":"16","author":"M Ramste","year":"2023","unstructured":"Ramste M, Ritvos M, H\u00e4yrynen S, Kiiski JI, Niemi M, Sinisalo J. CYP2C19 loss-of-function alleles and use of omeprazole or esomeprazole increase the risk of cardiovascular outcomes in patients using clopidogrel. Clin Transl Sci. 2023;16(10):2010\u201320. https:\/\/doi.org\/10.1111\/cts.13608.","journal-title":"Clin Transl Sci"},{"key":"1246_CR47","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.avsg.2023.05.023","volume":"95","author":"SP Suarez Ferreira","year":"2023","unstructured":"Suarez Ferreira SP, Hall RP, Majumdar M, Goudot G, Jessula S, Bellomo T, et al. Atorvastatin effect on clopidogrel efficacy in patients with peripheral artery disease. Ann Vasc Surg. 2023;95:74\u20139. https:\/\/doi.org\/10.1016\/j.avsg.2023.05.023.","journal-title":"Ann Vasc Surg"},{"issue":"1","key":"1246_CR48","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/s13318-014-0235-4","volume":"41","author":"X Boulenc","year":"2016","unstructured":"Boulenc X, Nicolas O, Hermabessi\u00e8re S, Zobouyan I, Martin V, Donazzolo Y, et al. CYP3A4-based drug-drug interaction: CYP3A4 substrates\u2019 pharmacokinetic properties and ketoconazole dose regimen effect. Eur J Drug Metab Pharmacokinet. 2016;41(1):45\u201354. https:\/\/doi.org\/10.1007\/s13318-014-0235-4.","journal-title":"Eur J Drug Metab Pharmacokinet"},{"issue":"3","key":"1246_CR49","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1007\/s11906-021-01131-y","volume":"23","author":"MA Fravel","year":"2021","unstructured":"Fravel MA, Ernst M. Drug interactions with antihypertensives. Curr Hypertens Rep. 2021;23(3):14. https:\/\/doi.org\/10.1007\/s11906-021-01131-y.","journal-title":"Curr Hypertens Rep"},{"issue":"12","key":"1246_CR50","doi-asserted-by":"publisher","first-page":"3173","DOI":"10.1161\/STROKEAHA.123.036886","volume":"54","author":"R Al-Shahi Salman","year":"2023","unstructured":"Al-Shahi Salman R, Greenberg SM. Antiplatelet agent use after stroke due to intracerebral hemorrhage. Stroke. 2023;54(12):3173\u201381. https:\/\/doi.org\/10.1161\/STROKEAHA.123.036886.","journal-title":"Stroke"},{"key":"1246_CR51","doi-asserted-by":"publisher","first-page":"544","DOI":"10.3109\/02688697.2015.1016892","volume":"29","author":"M Ahmed","year":"2015","unstructured":"Ahmed M, Sriganesh K, Vinay B, Umamaheswara Rao GS. Acute Kidney injury in survivors of surgery for severe traumatic brain injury: Incidence, risk factors and out come from a tertiary neuroscience center in India. Br J Neurosurg. 2015;29:544\u20138. https:\/\/doi.org\/10.3109\/02688697.2015.1016892.","journal-title":"Br J Neurosurg"},{"issue":"4","key":"1246_CR52","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1097\/CRD.0b013e3181ce1521","volume":"18","author":"M Amer","year":"2010","unstructured":"Amer M, Bead VR, Bathon J, Blumenthal RS, Edwards DN. Use of nonsteroidal anti-inflammatory drugs in patients with cardiovascular disease: a cautionary tale. Cardiol Rev. 2010;18(4):204\u201312. https:\/\/doi.org\/10.1097\/CRD.0b013e3181ce1521.","journal-title":"Cardiol Rev"},{"issue":"10","key":"1246_CR53","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1586\/14779072.2014.964687","volume":"12","author":"G Gargiulo","year":"2014","unstructured":"Gargiulo G, Capodanno D, Longo G, Capranzano P, Tamburino C. Updates on NSAIDs in patients with and without coronary artery disease: pitfalls, interactions and cardiovascular outcomes. Expert Rev Cardiovasc Ther. 2014;12(10):1185\u2013203. https:\/\/doi.org\/10.1586\/14779072.2014.964687.","journal-title":"Expert Rev Cardiovasc Ther"},{"issue":"1","key":"1246_CR54","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/s12877-020-1413-7","volume":"20","author":"BY Hailu","year":"2020","unstructured":"Hailu BY, Berhe DF, Gudina EK, Gidey K, Getachew M. Drug related problems in admitted geriatric patients: the impact of clinical pharmacist interventions. BMC Geriatr. 2020;20(1):13. https:\/\/doi.org\/10.1186\/s12877-020-1413-7.","journal-title":"BMC Geriatr"},{"issue":"8","key":"1246_CR55","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1016\/j.clinthera.2006.08.006","volume":"28","author":"CI Lindblad","year":"2006","unstructured":"Lindblad CI, Hanlon JT, Gross CR, Sloane RJ, Pieper CF, Hajjar ER, et al. Clinically important drug-disease interactions and their prevalence in older adults. Clin Ther. 2006;28(8):1133\u201343. https:\/\/doi.org\/10.1016\/j.clinthera.2006.08.006.","journal-title":"Clin Ther"},{"issue":"10","key":"1246_CR56","doi-asserted-by":"publisher","first-page":"549","DOI":"10.5694\/j.1326-5377.2006.tb00690.x","volume":"185","author":"H Krum","year":"2006","unstructured":"Krum H, Jelinek MV, Stewart S, Sindone A, Atherton JJ, Hawkes AL, et al. Guidelines for the prevention, detection and management of people with chronic heart failure in Australia 2006. Med J Aust. 2006;185(10):549\u201357. https:\/\/doi.org\/10.5694\/j.1326-5377.2006.tb00690.x.","journal-title":"Med J Aust"},{"issue":"5","key":"1246_CR57","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1161\/CIRCHEARTFAILURE.109.861013","volume":"2","author":"EE Roughead","year":"2009","unstructured":"Roughead EE, Barratt JD, Ramsay E, Pratt N, Ryan P, Peck R, et al. The effectiveness of collaborative medicine reviews in delaying time to next hospitalization for patients with heart failure in the practice setting: results of a cohort study. Circ Heart Fail. 2009;2(5):424\u20138. https:\/\/doi.org\/10.1161\/CIRCHEARTFAILURE.109.861013.","journal-title":"Circ Heart Fail"},{"key":"1246_CR58","doi-asserted-by":"publisher","DOI":"10.1590\/1518-8345.1316.2800","volume":"24","author":"MC Rodrigues","year":"2016","unstructured":"Rodrigues MC, Oliveira Cd. Drug-drug interactions and adverse drug reactions in polypharmacy among older adults: an integrative review. Rev Lat Am Enfermagem. 2016;24:e2800. https:\/\/doi.org\/10.1590\/1518-8345.1316.2800.","journal-title":"Rev Lat Am Enfermagem"},{"issue":"1","key":"1246_CR59","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1136\/ejhpharm-2019-002111","volume":"28","author":"LM de Oliveira","year":"2021","unstructured":"de Oliveira LM, Diel JDAC, Nunes A, da Silva Dal Pizzol T. Prevalence of drug interactions in hospitalised elderly patients: a systematic review. Eur J Hosp Pharm. 2021;28(1):4\u20139. https:\/\/doi.org\/10.1136\/ejhpharm-2019-002111.","journal-title":"Eur J Hosp Pharm"},{"issue":"4","key":"1246_CR60","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1111\/bcp.12596","volume":"80","author":"EA Davies","year":"2015","unstructured":"Davies EA, O\u2019Mahony MS. Adverse drug reactions in special populations the elderly. Br J Clin Pharmacol. 2015;80(4):796\u2013807. https:\/\/doi.org\/10.1111\/bcp.12596.","journal-title":"Br J Clin Pharmacol"},{"issue":"5","key":"1246_CR61","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1007\/s40264-015-0281-0","volume":"38","author":"JC Bouvy","year":"2015","unstructured":"Bouvy JC, De Bruin ML, Koopmanschap MA. Epidemiology of adverse drug reactions in Europe: a review of recent observational studies. Drug Saf. 2015;38(5):437\u201353. https:\/\/doi.org\/10.1007\/s40264-015-0281-0.","journal-title":"Drug Saf"},{"issue":"21","key":"1246_CR62","doi-asserted-by":"publisher","first-page":"2002","DOI":"10.1056\/NEJMsa1103053","volume":"365","author":"DS Budnitz","year":"2011","unstructured":"Budnitz DS, Lovegrove MC, Shehab N, Richards CL. Emergency hospitalizations for adverse drug events in older Americans. N Engl J Med. 2011;365(21):2002\u201312. https:\/\/doi.org\/10.1056\/NEJMsa1103053.","journal-title":"N Engl J Med"},{"issue":"10029","key":"1246_CR63","doi-asserted-by":"publisher","first-page":"1723","DOI":"10.1016\/S0140-6736(16)00163-X","volume":"387","author":"M Goyal","year":"2016","unstructured":"Goyal M, Menon BK, van Zwam WH, HERMES collaborators, et al. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet. 2016;387(10029):1723\u201331. https:\/\/doi.org\/10.1016\/S0140-6736(16)00163-X.","journal-title":"Lancet"},{"issue":"8","key":"1246_CR64","doi-asserted-by":"publisher","first-page":"708","DOI":"10.1056\/NEJMoa1713973","volume":"378","author":"GW Albers","year":"2018","unstructured":"Albers GW, Marks MP, Kemp S, Christensen S, Tsai JP, Ortega-Gutierrez S, et al. Thrombectomy for stroke at 6 to 16 hours with selection by perfusion imaging. N Engl J Med. 2018;378(8):708\u201318. https:\/\/doi.org\/10.1056\/NEJMoa1713973.","journal-title":"N Engl J Med"},{"issue":"1","key":"1246_CR65","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1056\/NEJMoa1706442","volume":"378","author":"RG Nogueira","year":"2018","unstructured":"Nogueira RG, Jadhav AP, Haussen DC, Bonafe A, Budzik RF, Bhuva P, et al. Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct. N Engl J Med. 2018;378(1):11\u201321. https:\/\/doi.org\/10.1056\/NEJMoa1706442. (et al.: DAWN Trial Investigators).","journal-title":"N Engl J Med"},{"issue":"12","key":"1246_CR66","doi-asserted-by":"publisher","first-page":"e344","DOI":"10.1161\/STR.0000000000000215","volume":"50","author":"WJ Powers","year":"2019","unstructured":"Powers WJ, Rabinstein AA, Ackerson T, Adeoye OM, Bambakidis NC, Becker K, et al. Guidelines for the Early Management of Patients with Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals from the American Heart Association\/American Stroke Association. Stroke. 2019;50(12):e344\u2013418. https:\/\/doi.org\/10.1161\/STR.0000000000000215. (Erratum in: Stroke. 2019 Dec;50(12): e440-e441).","journal-title":"Stroke"},{"issue":"5","key":"1246_CR67","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1161\/STROKEAHA.117.020125","volume":"49","author":"AH Siddiqui","year":"2018","unstructured":"Siddiqui AH, Bernard T, Claffey M, Andersson T. Primary Results of the multicenter ARISE II study (Analysis of Revascularization in Ischemic Stroke With EmboTrap). Stroke. 2018;49(5):1107\u201315. https:\/\/doi.org\/10.1161\/STROKEAHA.117.020125.","journal-title":"Stroke"},{"issue":"11","key":"1246_CR68","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1056\/NEJMoa1414792","volume":"372","author":"BC Campbell","year":"2015","unstructured":"Campbell BC, Mitchell PJ, Kleinig TJ, Dewey HM, Churilov L, Yassi N, et al. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med. 2015;372(11):1009\u201318. https:\/\/doi.org\/10.1056\/NEJMoa1414792.","journal-title":"N Engl J Med"},{"issue":"24","key":"1246_CR69","doi-asserted-by":"publisher","first-page":"2296","DOI":"10.1056\/NEJMoa1503780","volume":"372","author":"TG Jovin","year":"2015","unstructured":"Jovin TG, Chamorro A, Cobo E, de Miquel MA, Molina CA, Rovira A, et al. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med. 2015;372(24):2296\u2013306. https:\/\/doi.org\/10.1056\/NEJMoa1503780.","journal-title":"N Engl J Med"},{"issue":"24","key":"1246_CR70","doi-asserted-by":"publisher","first-page":"2285","DOI":"10.1056\/NEJMoa1415061","volume":"372","author":"JL Saver","year":"2015","unstructured":"Saver JL, Goyal M, Bonafe A, Diener HC, Levy EI, Pereira VM, et al. Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med. 2015;372(24):2285\u201395. https:\/\/doi.org\/10.1056\/NEJMoa1415061.","journal-title":"N Engl J Med"},{"issue":"11","key":"1246_CR71","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1056\/NEJMoa1414905","volume":"372","author":"M Goyal","year":"2015","unstructured":"Goyal M, Demchuk AM, Menon BK, Eesa M, Rempel JL, Thornton J, et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med. 2015;372(11):1019\u201330. https:\/\/doi.org\/10.1056\/NEJMoa1414905.","journal-title":"N Engl J Med"},{"issue":"1","key":"1246_CR72","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1056\/NEJMoa1411587","volume":"372","author":"OA Berkhemer","year":"2015","unstructured":"Berkhemer OA, Fransen PS, Beumer D, van den Berg LA, Lingsma HF, Yoo AJ, et al. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med. 2015;372(1):11\u201320. https:\/\/doi.org\/10.1056\/NEJMoa1411587. (Epub 2014 Dec 17. Erratum in: N Engl J Med. 2015 Jan 22;372(4):394. PMID: 25517348).","journal-title":"N Engl J Med"},{"issue":"5\u20136","key":"1246_CR73","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1159\/000356186","volume":"36","author":"W Kurre","year":"2013","unstructured":"Kurre W, Aguilar-P\u00e9rez M, Niehaus L, Fischer S, Schmid E, B\u00e4zner H, et al. Predictors of outcome after mechanical thrombectomy for anterior circulation large vessel occlusion in patients aged \u226580 years. Cerebrovasc Dis. 2013;36(5\u20136):430\u20136. https:\/\/doi.org\/10.1159\/000356186.","journal-title":"Cerebrovasc Dis"},{"issue":"5\u20136","key":"1246_CR74","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1159\/000356213","volume":"36","author":"OC Singer","year":"2013","unstructured":"Singer OC, Haring HP, Trenkler J, Nolte CH, Bohner G, Reich A, et al. Age dependency of successful recanalization in anterior circulation stroke: the ENDOSTROKE study. Cerebrovasc Dis. 2013;36(5\u20136):437\u201345. https:\/\/doi.org\/10.1159\/000356213.","journal-title":"Cerebrovasc Dis"},{"issue":"5","key":"1246_CR75","doi-asserted-by":"publisher","first-page":"887","DOI":"10.3174\/ajnr.A5598","volume":"39","author":"CA Hilditch","year":"2018","unstructured":"Hilditch CA, Nicholson P, Murad MH, Rabinstein A, Schaafsma J, Pikula A, et al. Endovascular management of acute stroke in the elderly: a systematic review and meta-analysis. AJNR Am J Neuroradiol. 2018;39(5):887\u201391. https:\/\/doi.org\/10.3174\/ajnr.A5598.","journal-title":"AJNR Am J Neuroradiol"},{"issue":"7","key":"1246_CR76","doi-asserted-by":"publisher","first-page":"2220","DOI":"10.1161\/STROKEAHA.121.037770","volume":"53","author":"RV McDonough","year":"2022","unstructured":"McDonough RV, Ospel JM, Campbell BCV, Hill MD, Saver JL, Dippel DWJ, et al. Functional outcomes of patients \u226585 years with acute ischemic stroke following EVT: a hermes sub study. Stroke. 2022;53(7):2220\u20136. https:\/\/doi.org\/10.1161\/STROKEAHA.121.037770.","journal-title":"Stroke"},{"issue":"8","key":"1246_CR77","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.26007","volume":"7","author":"L Winkelmeier","year":"2024","unstructured":"Winkelmeier L, Kniep H, Faizy T, Heitkamp C, Holtz L, Meyer L, et al. Age and functional outcomes in patients with large ischemic stroke receiving endovascular thrombectomy. JAMA Netw Open. 2024;7(8):e2426007. https:\/\/doi.org\/10.1001\/jamanetworkopen.2024.26007.","journal-title":"JAMA Netw Open"},{"issue":"1","key":"1246_CR78","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1177\/23969873221145778","volume":"8","author":"H Dunphy","year":"2023","unstructured":"Dunphy H, Garcia-Esperon C, Beom Hong J, Manoczki C, Wilson D, Lim Alvin Chew B, et al. Endovascular thrombectomy for acute ischaemic stroke improves and maintains function in the very elderly: a multicentre propensity score matched analysis. Eur Stroke J. 2023;8(1):191\u20138. https:\/\/doi.org\/10.1177\/23969873221145778.","journal-title":"Eur Stroke J"},{"issue":"1","key":"1246_CR79","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1186\/s40001-024-02027-8","volume":"29","author":"Q Liang","year":"2024","unstructured":"Liang Q, Feng M, Galecio-Castillo M, et al. Predictors of favorable functional outcomes for elderly patients undergoing endovascular thrombectomy for acute ischemic stroke. Eur J Med Res. 2024;29(1):429. https:\/\/doi.org\/10.1186\/s40001-024-02027-8.","journal-title":"Eur J Med Res"},{"key":"1246_CR80","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2024.1418415","volume":"15","author":"FM Ippen","year":"2024","unstructured":"Ippen FM, Schregel K, Ungerer M, Feisst M, Ringleb PA, Gumbinger CK. Outcomes in elderly patients undergoing endovascular thrombectomy in association with premorbid Rankin Scale scores. Front Neurol. 2024;15:1418415. https:\/\/doi.org\/10.3389\/fneur.2024.1418415.","journal-title":"Front Neurol"},{"issue":"6","key":"1246_CR81","doi-asserted-by":"publisher","first-page":"1574","DOI":"10.1161\/STROKEAHA.117.016745","volume":"48","author":"M Mokin","year":"2017","unstructured":"Mokin M, Primiani CT, Siddiqui AH, Turk AS. Aspects (Alberta Stroke Program Early CT Score) measurement using Hounsfield unit values when selecting patients for stroke thrombectomy. Stroke. 2017;48(6):1574\u20139. https:\/\/doi.org\/10.1161\/STROKEAHA.117.016745.","journal-title":"Stroke"},{"issue":"10414","key":"1246_CR82","doi-asserted-by":"publisher","first-page":"1753","DOI":"10.1016\/S0140-6736(23)02032-9","volume":"402","author":"M Bendszus","year":"2023","unstructured":"Bendszus M, Fiehler J, Subtil F, Bonekamp S, Aamodt AH, Fuentes B, et al. Endovascular thrombectomy for acute ischaemic stroke with established large infarct: multicentre, open-label, randomised trial. Lancet. 2023;402(10414):1753\u201363. https:\/\/doi.org\/10.1016\/S0140-6736(23)02032-9.","journal-title":"Lancet"},{"issue":"14","key":"1246_CR83","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1056\/NEJMoa2118191","volume":"386","author":"S Yoshimura","year":"2022","unstructured":"Yoshimura S, Sakai N, Yamagami H, Uchida K, Beppu M, Toyoda K, et al. Endovascular therapy for acute stroke with a large ischemic region. N Engl J Med. 2022;386(14):1303\u201313. https:\/\/doi.org\/10.1056\/NEJMoa2118191.","journal-title":"N Engl J Med"},{"issue":"14","key":"1246_CR84","doi-asserted-by":"publisher","first-page":"1259","DOI":"10.1056\/NEJMoa2214403","volume":"388","author":"A Sarraj","year":"2023","unstructured":"Sarraj A, Hassan AE, Abraham MG, Ortega-Gutierrez S, Kasner SE, Hussain MS, et al. Trial of endovascular thrombectomy for large ischemic strokes. N Engl J Med. 2023;388(14):1259\u201371. https:\/\/doi.org\/10.1056\/NEJMoa2214403.","journal-title":"N Engl J Med"},{"key":"1246_CR85","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1056\/NEJMoa2213379","volume":"388","author":"X Huo","year":"2023","unstructured":"Huo X, Ma G, Tong X, Zhang X, Pan Y, Nguyen TN, et al. Trial of endovascular therapy for acute ischemic stroke with large infarct. N Engl J Med. 2023;388:1272\u201383. https:\/\/doi.org\/10.1056\/NEJMoa2213379.","journal-title":"N Engl J Med"},{"issue":"18","key":"1246_CR86","doi-asserted-by":"publisher","first-page":"1677","DOI":"10.1056\/NEJMoa2314063","volume":"390","author":"V Costalat","year":"2024","unstructured":"Costalat V, Jovin TG, Albucher JF, Cognard C, Henon H, Nouri N, et al. Trial of thrombectomy for stroke with a large infarct of unrestricted size. N Engl J Med. 2024;390(18):1677\u201389. https:\/\/doi.org\/10.1056\/NEJMoa2314063.","journal-title":"N Engl J Med"},{"issue":"3","key":"1246_CR87","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1161\/STROKEAHA.119.028337","volume":"51","author":"J Demeestere","year":"2020","unstructured":"Demeestere J, Wouters A, Christensen S, Lemmens R, Lansberg MG. Review of perfusion imaging in acute ischemic stroke: from time to tissue. Stroke. 2020;51(3):1017\u201324. https:\/\/doi.org\/10.1161\/STROKEAHA.119.028337.","journal-title":"Stroke"},{"key":"1246_CR88","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1056\/NEJMoa1804355","volume":"379","author":"G Thomalla","year":"2018","unstructured":"Thomalla G, Simonsen CZ, Boutitie F, Andersen G, Berthezene Y, Cheng B, et al. MRI-guided thrombolysis for stroke with unknown time of onset. N Engl J Med. 2018;379:611\u201322. https:\/\/doi.org\/10.1056\/NEJMoa1804355.","journal-title":"N Engl J Med"},{"issue":"7","key":"1246_CR89","doi-asserted-by":"publisher","first-page":"864","DOI":"10.1161\/01.str.20.7.864","volume":"20","author":"T Brott","year":"1989","unstructured":"Brott T, Adams HP Jr., Olinger CP, Marler JR, Barsan WG, Biller J, et al. Measurements of acute cerebral infarction: a clinical examination scale. Stroke. 1989;20(7):864\u201370. https:\/\/doi.org\/10.1161\/01.str.20.7.864.","journal-title":"Stroke"},{"issue":"1","key":"1246_CR90","doi-asserted-by":"publisher","DOI":"10.1161\/SVIN.122.000512","volume":"3","author":"TN Nguyen","year":"2023","unstructured":"Nguyen TN, Castonguay AC, Siegler JE, Nagel S, Lansberg MG, de Havenon A, et al. Mechanical thrombectomy in the late presentation of anterior circulation large vessel occlusion stroke: a guideline from the Society of Vascular and Interventional Neurology Guidelines and Practice Standards Committee. Stroke Vasc Interv Neurol. 2023;3(1):e000512. https:\/\/doi.org\/10.1161\/SVIN.122.000512.","journal-title":"Stroke Vasc Interv Neurol."},{"issue":"3","key":"1246_CR91","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1136\/neurintsurg-2018-014640","volume":"11","author":"M Mokin","year":"2019","unstructured":"Mokin M, Ansari SA, McTaggart RA, Bulsara KR, Goyal M, Chen M, et al. Indications for thrombectomy in acute ischemic stroke from emergent large vessel occlusion (ELVO): report of the SNIS standards and guidelines committee. J Neurointerv Surg. 2019;11(3):215\u201320. https:\/\/doi.org\/10.1136\/neurintsurg-2018-014640.","journal-title":"J Neurointerv Surg"},{"issue":"8","key":"1246_CR92","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1177\/17474930231180446","volume":"18","author":"J Du","year":"2023","unstructured":"Du J, Wang Y, Che B, Miao M, Bao A, Peng Y, et al. The relationship between neurological function trajectory, assessed by repeated NIHSS measurement, and long-term cardiovascular events, recurrent stroke, and mortality after ischemic stroke. Int J Stroke. 2023;18(8):1005\u201314. https:\/\/doi.org\/10.1177\/17474930231180446.","journal-title":"Int J Stroke"},{"issue":"4","key":"1246_CR93","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.jstrokecerebrovasdis.2008.01.008","volume":"17","author":"BC Meyer","year":"2008","unstructured":"Meyer BC, Raman R, Chacon MR, Jensen M, Werner JD. Reliability of site-independent telemedicine when assessed by telemedicine-naive stroke practitioners. J Stroke Cerebrovasc Dis. 2008;17(4):181\u20136. https:\/\/doi.org\/10.1016\/j.jstrokecerebrovasdis.2008.01.008.","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"1246_CR94","doi-asserted-by":"publisher","first-page":"201","DOI":"10.2147\/CIA.S32405","volume":"8","author":"JK Harrison","year":"2013","unstructured":"Harrison JK, McArthur KS, Quinn TJ. Assessment scales in stroke: clinimetric and clinical considerations. Clin Interv Aging. 2013;8:201\u201311. https:\/\/doi.org\/10.2147\/CIA.S32405.","journal-title":"Clin Interv Aging"},{"issue":"8","key":"1246_CR95","doi-asserted-by":"publisher","first-page":"2547","DOI":"10.1161\/STROKEAHA.120.032487","volume":"52","author":"EA Mistry","year":"2021","unstructured":"Mistry EA, Yeatts S, de Havenon A, Mehta T, Arora N, De Los Rios La RosaStarosciak FAK, et al. Predicting 90-day outcome after thrombectomy: baseline-adjusted 24-hour NIHSS is more powerful than NIHSS score change. Stroke. 2021;52(8):2547\u201353. https:\/\/doi.org\/10.1161\/STROKEAHA.120.032487.","journal-title":"Stroke"},{"issue":"2","key":"1246_CR96","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1007\/s00062-021-01068-4","volume":"32","author":"P Hendrix","year":"2022","unstructured":"Hendrix P, Melamed I, Collins M, Lieberman N, Sharma V, Goren O, et al. NIHSS 24 h after mechanical thrombectomy predicts 90-day functional outcome. Clin Neuroradiol. 2022;32(2):401\u20136. https:\/\/doi.org\/10.1007\/s00062-021-01068-4.","journal-title":"Clin Neuroradiol"},{"issue":"1","key":"1246_CR97","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1212\/wnl.53.1.126","volume":"53","author":"HP Adams Jr","year":"1999","unstructured":"Adams HP Jr, Davis PH, Leira EC, Chang KC, Bendixen BH, Clarke WR, et al. Baseline NIH Stroke Scale score strongly predicts outcome after stroke: a report of the Trial of Org 10172 in Acute Stroke Treatment (TOAST). Neurology. 1999;53(1):126\u201331. https:\/\/doi.org\/10.1212\/wnl.53.1.126.","journal-title":"Neurology"},{"issue":"1","key":"1246_CR98","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.annemergmed.2010.06.564","volume":"57","author":"S Martin-Schild","year":"2011","unstructured":"Martin-Schild S, Albright KC, Tanksley J, Pandav V, Jones EB, Grotta JC, et al. Zero on the NIHSS does not equal the absence of stroke. Ann Emerg Med. 2011;57(1):42\u20135. https:\/\/doi.org\/10.1016\/j.annemergmed.2010.06.564.","journal-title":"Ann Emerg Med"},{"issue":"11","key":"1246_CR99","doi-asserted-by":"publisher","first-page":"2355","DOI":"10.1161\/01.str.30.11.2355.s","volume":"30","author":"D Woo","year":"1999","unstructured":"Woo D, Broderick JP, Kothari RU, Lu M, Brott T, Lyden PD, et al. Does the National Institutes of Health Stroke Scale favor left hemisphere strokes? NINDS t-PA Stroke Study Group. Stroke. 1999;30(11):2355\u20139. https:\/\/doi.org\/10.1161\/01.str.30.11.2355.s.","journal-title":"Stroke"},{"issue":"1","key":"1246_CR100","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1097\/MEJ.0000000000000550","volume":"26","author":"G McClelland","year":"2019","unstructured":"McClelland G, Rodgers H, Flynn D, Price CI. The frequency, characteristics and aetiology of stroke mimic presentations: a narrative review. Eur J Emerg Med. 2019;26(1):2\u20138. https:\/\/doi.org\/10.1097\/MEJ.0000000000000550.","journal-title":"Eur J Emerg Med"},{"issue":"2","key":"1246_CR101","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1136\/neurintsurg-2017-012993","volume":"10","author":"N Goyal","year":"2018","unstructured":"Goyal N, Tsivgoulis G, Pandhi A, Dillard K, Katsanos AH, Magoufis G, et al. Admission hyperglycemia and outcomes in large vessel occlusion strokes treated with mechanical thrombectomy. J Neurointerv Surg. 2018;10(2):112\u20137. https:\/\/doi.org\/10.1136\/neurintsurg-2017-012993.","journal-title":"J Neurointerv Surg."},{"issue":"1","key":"1246_CR102","doi-asserted-by":"publisher","DOI":"10.1186\/s42466-025-00393-0","volume":"7","author":"A Filipov","year":"2025","unstructured":"Filipov A, Andermann M, Lepski G, Ar\u00e9valo A, Hilgenfeld T, Sch\u00f6nenberger S, et al. Admission glucose is a significant outcome predictor in anterior circulation stroke: approaching the sweet spot. Neurol Res Pract. 2025;7(1):39. https:\/\/doi.org\/10.1186\/s42466-025-00393-0.","journal-title":"Neurol Res Pract"},{"issue":"3","key":"1246_CR103","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1161\/STROKEAHA.118.023769","volume":"50","author":"\u00c1 Chamorro","year":"2019","unstructured":"Chamorro \u00c1, Brown S, Amaro S, Hill MD, Muir KW, Dippel DWJ, et al. Glucose modifies the effect of endovascular thrombectomy in patients with acute stroke. Stroke. 2019;50(3):690\u20136. https:\/\/doi.org\/10.1161\/STROKEAHA.118.023769.","journal-title":"Stroke"},{"issue":"8","key":"1246_CR104","doi-asserted-by":"publisher","first-page":"2295","DOI":"10.1161\/STROKEAHA.106.471813","volume":"38","author":"J Prosser","year":"2007","unstructured":"Prosser J, MacGregor L, Lees KR, Diener HC, Hacke W, Davis S, et al. Predictors of early cardiac morbidity and mortality after ischemic stroke. Stroke. 2007;38(8):2295\u2013302. https:\/\/doi.org\/10.1161\/STROKEAHA.106.471813.","journal-title":"Stroke"},{"issue":"12","key":"1246_CR105","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1016\/S1474-4422(18)30336-3","volume":"17","author":"JF Scheitz","year":"2018","unstructured":"Scheitz JF, Nolte CH, Doehner W, Hachinski V, Endres M. Stroke-heart syndrome: clinical presentation and underlying mechanisms. Lancet Neurol. 2018;17(12):1109\u201320. https:\/\/doi.org\/10.1016\/S1474-4422(18)30336-3.","journal-title":"Lancet Neurol"},{"issue":"6","key":"1246_CR106","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2022","volume":"31","author":"Y Zhang","year":"2022","unstructured":"Zhang Y, Ouyang M, Qiu J, Cao X, Xu B, Sui Y. Prognostic value of serum cardiac troponin in acute ischemic stroke: an updated systematic review and meta-analysis. J Stroke Cerebrovasc Dis. 2022;31(6):106444. https:\/\/doi.org\/10.1016\/j.jstrokecerebrovasdis.2022.","journal-title":"J Stroke Cerebrovasc Dis"},{"issue":"3","key":"1246_CR107","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1016\/j.ijcard.2014.10.036","volume":"177","author":"JF Scheitz","year":"2014","unstructured":"Scheitz JF, Mochmann HC, Erdur H, T\u00fct\u00fcnc\u00fc S, Haeusler KG, Grittner U, et al. Prognostic relevance of cardiac troponin T levels and their dynamic changes measured with a high-sensitivity assay in acute ischaemic stroke: analyses from the TRELAS cohort. Int J Cardiol. 2014;177(3):886\u201393. https:\/\/doi.org\/10.1016\/j.ijcard.2014.10.036.","journal-title":"Int J Cardiol"},{"issue":"5","key":"1246_CR108","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1161\/STROKEAHA.116.014561","volume":"48","author":"P Wrigley","year":"2017","unstructured":"Wrigley P, Khoury J, Eckerle B, Alwell K, Moomaw CJ, Woo D, et al. Prevalence of positive troponin and echocardiogram findings and association with mortality in acute ischemic stroke. Stroke. 2017;48(5):1226\u201332. https:\/\/doi.org\/10.1161\/STROKEAHA.116.014561.","journal-title":"Stroke"},{"issue":"6","key":"1246_CR109","doi-asserted-by":"publisher","first-page":"2284","DOI":"10.1007\/s00415-020-10349-w","volume":"268","author":"JF Scheitz","year":"2021","unstructured":"Scheitz JF, Stengl H, Nolte CH, Landmesser U, Endres M. Neurological update: Use of cardiac troponin in patients with stroke. J Neurol. 2021;268(6):2284\u201392. https:\/\/doi.org\/10.1007\/s00415-020-10349-w.","journal-title":"J Neurol"},{"issue":"11","key":"1246_CR110","doi-asserted-by":"publisher","first-page":"2892","DOI":"10.1161\/STROKEAHA.112.664318","volume":"43","author":"B Kallm\u00fcnzer","year":"2012","unstructured":"Kallm\u00fcnzer B, Breuer L, Kahl N, Bobinger T, Raaz-Schrauder D, Huttner HB, et al. Serious cardiac arrhythmias after stroke: incidence, time course, and predictors\u2013a systematic, prospective analysis. Stroke. 2012;43(11):2892\u20137. https:\/\/doi.org\/10.1161\/STROKEAHA.112.664318.","journal-title":"Stroke"},{"issue":"1","key":"1246_CR111","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1002\/ejhf.424","volume":"18","author":"AR Lyon","year":"2016","unstructured":"Lyon AR, Bossone E, Schneider B, Sechtem U, Citro R, Underwood SR, et al. Current state of knowledge on Takotsubo syndrome: a position statement from the Taskforce on Takotsubo Syndrome of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail. 2016;18(1):8\u201327. https:\/\/doi.org\/10.1002\/ejhf.424.","journal-title":"Eur J Heart Fail"},{"key":"1246_CR112","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2023.131283","volume":"392","author":"N Jessen","year":"2023","unstructured":"Jessen N, Andersen JA, Tayal B, \u00d8stergaard L, Andersen MP, Schmidt M, et al. Takotsubo syndrome and stroke risk: a nationwide register-based study. Int J Cardiol. 2023;392:131283. https:\/\/doi.org\/10.1016\/j.ijcard.2023.131283.","journal-title":"Int J Cardiol"},{"issue":"10","key":"1246_CR113","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1007\/s00392-010-0200-4","volume":"99","author":"U Laufs","year":"2010","unstructured":"Laufs U, Hoppe UC, Rosenkranz S, Kirchhof P, B\u00f6hm M, Diener HC, et al. Cardiological evaluation after cerebral ischaemia: consensus statement of the Working Group Heart and Brain of the German Cardiac Society-Cardiovascular Research (DGK) and the German Stroke Society (DSG). Clin Res Cardiol. 2010;99(10):609\u201325. https:\/\/doi.org\/10.1007\/s00392-010-0200-4.","journal-title":"Clin Res Cardiol"},{"issue":"6","key":"1246_CR114","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1016\/j.rec.2021.05.002","volume":"74","author":"JP Collet","year":"2021","unstructured":"Collet JP, Thiele H, Barbato E, Barth\u00e9l\u00e9my O, Bauersachs J, Bhatt DL, et al. 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Rev Esp Cardiol (Engl Ed). 2021;74(6):544. https:\/\/doi.org\/10.1016\/j.rec.2021.05.002. (English, Spanish).","journal-title":"Rev Esp Cardiol (Engl Ed)."},{"issue":"6","key":"1246_CR115","doi-asserted-by":"publisher","first-page":"1115","DOI":"10.1161\/01.STR.0000166053.83476.4a","volume":"36","author":"C Marini","year":"2005","unstructured":"Marini C, De Santis F, Sacco S, Russo T, Olivieri L, Totaro R, et al. Contribution of atrial fibrillation to incidence and outcome of ischemic stroke: results from a population-based study. Stroke. 2005;36(6):1115\u20139. https:\/\/doi.org\/10.1161\/01.STR.0000166053.83476.4a.","journal-title":"Stroke"},{"key":"1246_CR116","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2020.00003","volume":"7","author":"M Kavousi","year":"2020","unstructured":"Kavousi M. Differences in epidemiology and risk factors for atrial fibrillation between women and men. Front Cardiovasc Med. 2020;7:3. https:\/\/doi.org\/10.3389\/fcvm.2020.00003.","journal-title":"Front Cardiovasc Med"},{"issue":"10","key":"1246_CR117","doi-asserted-by":"publisher","first-page":"1607","DOI":"10.1016\/j.cjca.2021.06.011","volume":"37","author":"CC Cheung","year":"2021","unstructured":"Cheung CC, Nattel S, Macle L, Andrade JG. Management of atrial fibrillation in 2021: an updated comparison of the current CCS\/CHRS, ESC, and AHA\/ACC\/HRS guidelines. Can J Cardiol. 2021;37(10):1607\u201318. https:\/\/doi.org\/10.1016\/j.cjca.2021.06.011.","journal-title":"Can J Cardiol"},{"issue":"3","key":"1246_CR118","doi-asserted-by":"publisher","first-page":"321","DOI":"10.5853\/jos.2018.01788","volume":"20","author":"K Toyoda","year":"2018","unstructured":"Toyoda K, Yamagami H, Koga M. Consensus guides on stroke thrombolysis for anticoagulated patients from Japan: application to other populations. J Stroke. 2018;20(3):321\u201331. https:\/\/doi.org\/10.5853\/jos.2018.01788.","journal-title":"J Stroke"},{"issue":"24","key":"1246_CR119","doi-asserted-by":"publisher","first-page":"2600","DOI":"10.1001\/jama.2012.6756","volume":"307","author":"Y Xian","year":"2012","unstructured":"Xian Y, Liang L, Smith EE, Schwamm LH, Reeves MJ, Olson DM, et al. Risks of intracranial hemorrhage among patients with acute ischemic stroke receiving warfarin and treated with intravenous tissue plasminogen activator. JAMA. 2012;307(24):2600\u20138. https:\/\/doi.org\/10.1001\/jama.2012.6756.","journal-title":"JAMA"},{"issue":"1","key":"1246_CR120","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1017\/cjn.2022.344","volume":"51","author":"M Heran","year":"2024","unstructured":"Heran M, Lindsay P, Gubitz G, Yu A, Ganesh A, Lund R, et al. Canadian stroke best practice recommendations: acute stroke management, 7th edition practice guidelines update, 2022. Can J Neurol Sci. 2024;51(1):1\u201331. https:\/\/doi.org\/10.1017\/cjn.2022.344.","journal-title":"Can J Neurol Sci"},{"issue":"1","key":"1246_CR121","doi-asserted-by":"publisher","first-page":"I","DOI":"10.1177\/2396987321989865","volume":"6","author":"E Berge","year":"2021","unstructured":"Berge E, Whiteley W, Audebert H, De Marchis GM, Fonseca AC, Padiglioni C, et al. European Stroke Organisation (ESO) guidelines on intravenous thrombolysis for acute ischaemic stroke. Eur Stroke J. 2021;6(1):I\u2013LXII. https:\/\/doi.org\/10.1177\/2396987321989865.","journal-title":"Eur Stroke J"},{"issue":"10406","key":"1246_CR122","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1016\/S0140-6736(23)01142-X","volume":"402","author":"CB Majoie","year":"2023","unstructured":"Majoie CB, Cavalcante F, Gralla J, Yang P, Kaesmacher J, Treurniet KM, et al. Value of intravenous thrombolysis in endovascular treatment for large-vessel anterior circulation stroke: individual participant data meta-analysis of six randomised trials. Lancet. 2023;402(10406):965\u201374. https:\/\/doi.org\/10.1016\/S0140-6736(23)01142-X.","journal-title":"Lancet"},{"issue":"3","key":"1246_CR123","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1136\/neurintsurg-2021-018589","volume":"14","author":"G Turc","year":"2022","unstructured":"Turc G, Tsivgoulis G, Audebert HJ, Boogaarts H, Bhogal P, De Marchis GM, et al. European Stroke Organisation (ESO)-European Society for Minimally Invasive Neurological Therapy (ESMINT) expedited recommendation on indication for intravenous thrombolysis before mechanical thrombectomy in patients with acute ischemic stroke and anterior circulation large vessel occlusion. J Neurointerv Surg. 2022;14(3):209. https:\/\/doi.org\/10.1136\/neurintsurg-2021-018589.","journal-title":"J Neurointerv Surg."},{"issue":"1","key":"1246_CR124","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1002\/ana.25269","volume":"84","author":"G Tsivgoulis","year":"2018","unstructured":"Tsivgoulis G, Katsanos AH, Mavridis D, Gdovinova Z, Karli\u0144ski M, Macleod MJ, et al. Intravenous thrombolysis for ischemic stroke patients on dual antiplatelets. Ann Neurol. 2018;84(1):89\u201397. https:\/\/doi.org\/10.1002\/ana.25269.","journal-title":"Ann Neurol"},{"issue":"4","key":"1246_CR125","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1177\/1747493020946975","volume":"16","author":"RA van de Graaf","year":"2021","unstructured":"van de Graaf RA, Zinkstok SM, Chalos V, Goldhoorn RB, Majoie CB, van Oostenbrugge RJ, et al. Prior antiplatelet therapy in patients undergoing endovascular treatment for acute ischemic stroke: results from the MR CLEAN Registry. Int J Stroke. 2021;16(4):476\u201385. https:\/\/doi.org\/10.1177\/1747493020946975.","journal-title":"Int J Stroke"},{"issue":"7","key":"1246_CR126","doi-asserted-by":"publisher","first-page":"e657","DOI":"10.1212\/WNL.0000000000008961","volume":"94","author":"K Malhotra","year":"2020","unstructured":"Malhotra K, Katsanos AH, Goyal N, Ahmed N, Strbian D, Palaiodimou L, et al. Safety and efficacy of dual antiplatelet pretreatment in patients with ischemic stroke treated with IV thrombolysis: a systematic review and meta-analysis. Neurology. 2020;94(7):e657\u201366. https:\/\/doi.org\/10.1212\/WNL.0000000000008961.","journal-title":"Neurology"},{"key":"1246_CR127","doi-asserted-by":"crossref","unstructured":"The International Stroke Trial (IST): a randomised trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischaemic stroke. International Stroke Trial Collaborative Group. Lancet. 1997;349(9065):1569-81. (PMID: 9174558).","DOI":"10.1016\/S0140-6736(97)04011-7"},{"issue":"1","key":"1246_CR128","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1056\/NEJMoa1215340","volume":"369","author":"Y Wang","year":"2013","unstructured":"Wang Y, Wang Y, Zhao X, Liu L, Wang D, Wang C, et al. Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med. 2013;369(1):11\u20139. https:\/\/doi.org\/10.1056\/NEJMoa1215340.","journal-title":"N Engl J Med"},{"issue":"3","key":"1246_CR129","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1056\/NEJMoa1800410","volume":"379","author":"SC Johnston","year":"2018","unstructured":"Johnston SC, Easton JD, Farrant M, Barsan W, Conwit RA, Elm JJ, et al. Clopidogrel and aspirin in acute ischemic stroke and high-risk TIA. N Engl J Med. 2018;379(3):215\u201325. https:\/\/doi.org\/10.1056\/NEJMoa1800410.","journal-title":"N Engl J Med"},{"issue":"4","key":"1246_CR130","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.121.022638","volume":"11","author":"NE Vinding","year":"2022","unstructured":"Vinding NE, Kristensen SL, R\u00f8rth R, Butt JH, \u00d8stergaard L, Olesen JB, et al. Ischemic stroke severity and mortality in patients with and without atrial fibrillation. J Am Heart Assoc. 2022;11(4):e022638. https:\/\/doi.org\/10.1161\/JAHA.121.022638.","journal-title":"J Am Heart Assoc"},{"issue":"40","key":"1246_CR131","doi-asserted-by":"publisher","first-page":"4194","DOI":"10.1093\/eurheartj\/ehab648","volume":"42","author":"G Hindricks","year":"2021","unstructured":"Hindricks G, Potpara T, Dagres N, Arbelo E, Bax JJ, Blomstr\u00f6m-Lundqvist C, et al. Corrigendum to: 2020 ESC guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): the Task Force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC. Eur Heart J. 2021;42(40):4194. https:\/\/doi.org\/10.1093\/eurheartj\/ehab648. (Erratum for: Eur Heart J. 2021 Feb 1;42(5):373-498. doi: 10.1093\/eurheartj\/ehaa612).","journal-title":"Eur Heart J"},{"issue":"5","key":"1246_CR132","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1111\/ijs.12264","volume":"9","author":"A Rowat","year":"2014","unstructured":"Rowat A, Graham C, Dennis M. Renal dysfunction in stroke patients: a hospital-based cohort study and systematic review. Int J Stroke. 2014;9(5):633\u20139. https:\/\/doi.org\/10.1111\/ijs.12264.","journal-title":"Int J Stroke"},{"issue":"1","key":"1246_CR133","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.jstrokecerebrovasdis.2012.09.010","volume":"23","author":"S Cutting","year":"2014","unstructured":"Cutting S, Castro C, Lee VH, Prabhakaran S. Impaired renal function is not associated with increased volume of intracerebral hemorrhage. J Stroke Cerebrovasc Dis. 2014;23(1):86\u201390. https:\/\/doi.org\/10.1016\/j.jstrokecerebrovasdis.2012.09.010.","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"1246_CR134","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1161\/STROKEAHA.115.012360","volume":"47","author":"BC Campbell","year":"2016","unstructured":"Campbell BC, Hill MD, Rubiera M, Menon BK, Demchuk A, Donnan GA, et al. Safety and efficacy of Solitaire stent thrombectomy: individual patient data meta-analysis of randomized trials. Stroke. 2016;47:798\u2013806. https:\/\/doi.org\/10.1161\/STROKEAHA.115.012360.","journal-title":"Stroke"},{"key":"1246_CR135","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00254","volume":"10","author":"A Sharobeam","year":"2019","unstructured":"Sharobeam A, Cordato DJ, Manning N, Cheung A, Wenderoth J, Cappelen-Smith C. Functional outcomes at 90 days in octogenarians undergoing thrombectomy for acute ischemic stroke: a prospective cohort study and meta-analysis. Front Neurol. 2019;10:254. https:\/\/doi.org\/10.3389\/fneur.2019.00254.","journal-title":"Front Neurol"},{"issue":"7","key":"1246_CR136","doi-asserted-by":"publisher","first-page":"2227","DOI":"10.1161\/STROKEAHA.122.039340","volume":"53","author":"CJ Creutzfeldt","year":"2022","unstructured":"Creutzfeldt CJ, Levitt MR, Leslie-Mazwi TM. Is endovascular thrombectomy for the very elderly? Stroke. 2022;53(7):2227\u20139. https:\/\/doi.org\/10.1161\/STROKEAHA.122.039340.","journal-title":"Stroke"},{"issue":"1","key":"1246_CR137","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1159\/000512203","volume":"50","author":"S Finitsis","year":"2021","unstructured":"Finitsis S, Epstein J, Richard S, Bourcier R, Sibon I, Dargazanli C, et al. Age and outcome after endovascular treatment in anterior circulation large-vessel occlusion stroke: ETIS registry results. Cerebrovasc Dis. 2021;50(1):68\u201377. https:\/\/doi.org\/10.1159\/000512203.","journal-title":"Cerebrovasc Dis"},{"issue":"5","key":"1246_CR138","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.119.014447","volume":"9","author":"L Meyer","year":"2020","unstructured":"Meyer L, Alexandrou M, Flottmann F, Deb-Chatterji M, Abdullayev N, Maus V, et al. Endovascular treatment of very elderly patients aged \u226590 with acute ischemic stroke. J Am Heart Assoc. 2020;9(5):e014447. https:\/\/doi.org\/10.1161\/JAHA.119.014447.","journal-title":"J Am Heart Assoc"},{"issue":"1","key":"1246_CR139","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1136\/neurintsurg-2020-015889","volume":"13","author":"N van Horn","year":"2021","unstructured":"van Horn N, Kniep H, Leischner H, McDonough R, Deb-Chatterji M, Broocks G, Thomalla G, Brekenfeld C, Fiehler J, Hanning U, Flottmann F. Predictors of poor clinical outcome despite complete reperfusion in acute ischemic stroke patients. J Neurointerv Surg. 2021;13(1):14\u20138. https:\/\/doi.org\/10.1136\/neurintsurg-2020-015889.","journal-title":"J Neurointerv Surg."},{"issue":"1","key":"1246_CR140","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-025-01427-5","volume":"25","author":"BJ Bond","year":"2025","unstructured":"Bond BJ. Systemic comorbidities as modifiers of outcome after endovascular thrombectomy for acute ischemic stroke. Curr Neurol Neurosci Rep. 2025;25(1):38. https:\/\/doi.org\/10.1007\/s11910-025-01427-5.","journal-title":"Curr Neurol Neurosci Rep"},{"issue":"11","key":"1246_CR141","doi-asserted-by":"publisher","first-page":"1138","DOI":"10.1016\/S1474-4422(16)30177-6","volume":"15","author":"S Bracard","year":"2016","unstructured":"Bracard S, Ducrocq X, Mas JL, Soudant M, Oppenheim C, Moulin T, et al. Mechanical thrombectomy after intravenous alteplase versus alteplase alone after stroke (THRACE): a randomised controlled trial. Lancet Neurol. 2016;15(11):1138\u201347. https:\/\/doi.org\/10.1016\/S1474-4422(16)30177-6.","journal-title":"Lancet Neurol"},{"issue":"6","key":"1246_CR142","doi-asserted-by":"publisher","first-page":"e645","DOI":"10.1212\/WNL.0000000000207479","volume":"101","author":"MB Downer","year":"2023","unstructured":"Downer MB, Li L, Carter S, Beebe S, Rothwell PM. Associations of multimorbidity with stroke severity, subtype, premorbid disability, and early mortality: Oxford Vascular Study. Neurology. 2023;101(6):e645\u201352. https:\/\/doi.org\/10.1212\/WNL.0000000000207479.","journal-title":"Neurology"},{"key":"1246_CR143","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-014-0151-0","volume":"12","author":"KI Gallacher","year":"2014","unstructured":"Gallacher KI, Batty GD, McLean G, Mercer SW, Guthrie B, May CR, et al. Stroke, multimorbidity and polypharmacy in a nationally representative sample of 1,424,378 patients in Scotland: implications for treatment burden. BMC Med. 2014;12:151. https:\/\/doi.org\/10.1186\/s12916-014-0151-0.","journal-title":"BMC Med"},{"key":"1246_CR144","doi-asserted-by":"publisher","first-page":"239698732513321","DOI":"10.1177\/23969873251332136","volume":"12","author":"E Hall","year":"2025","unstructured":"Hall E, Hansen B, Pihlsg\u00e5rd M, Esbj\u00f6rnsson M, Norrving B, Ullberg T, et al. The impact of comorbidity burden on outcomes following endovascular thrombectomy for acute ischemic stroke: a nationwide prospective observational study. Eur Stroke J. 2025;12:23969873251332136. https:\/\/doi.org\/10.1177\/23969873251332136.","journal-title":"Eur Stroke J"},{"issue":"6","key":"1246_CR145","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1016\/j.cmet.2008.03.010","volume":"7","author":"C Iadecola","year":"2008","unstructured":"Iadecola C, Davisson RL. Hypertension and cerebrovascular dysfunction. Cell Metab. 2008;7(6):476\u201384. https:\/\/doi.org\/10.1016\/j.cmet.2008.03.010.","journal-title":"Cell Metab"},{"issue":"7","key":"1246_CR146","doi-asserted-by":"publisher","first-page":"1751","DOI":"10.1161\/STROKEAHA.119.025142","volume":"50","author":"K Fujita","year":"2019","unstructured":"Fujita K, Tanaka K, Yamagami H, Ide T, Ishiyama H, Sonoda K, et al. Detrimental effect of chronic hypertension on leptomeningeal collateral flow in acute ischemic stroke. Stroke. 2019;50(7):1751\u20137. https:\/\/doi.org\/10.1161\/STROKEAHA.119.025142.","journal-title":"Stroke"},{"issue":"16","key":"1246_CR147","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000019803","volume":"99","author":"Z Yuan","year":"2020","unstructured":"Yuan Z, Chen N, Zhou M, Guo J, Zhang Y, Li Y, et al. Effects of hypertension in patients receiving mechanical thrombectomy: a meta-analysis. Medicine (Baltimore). 2020;99(16):e19803. https:\/\/doi.org\/10.1097\/MD.0000000000019803.","journal-title":"Medicine (Baltimore)"},{"issue":"6","key":"1246_CR148","doi-asserted-by":"publisher","first-page":"1460","DOI":"10.1161\/STROKEAHA.119.024889","volume":"50","author":"ACO Tsang","year":"2019","unstructured":"Tsang ACO, Orru E, Klostranec JM, Yang IH, Lau KK, Tsang FCP, et al. Thrombectomy outcomes of intracranial atherosclerosis-related occlusions. Stroke. 2019;50(6):1460\u20136. https:\/\/doi.org\/10.1161\/STROKEAHA.119.024889.","journal-title":"Stroke"},{"issue":"7","key":"1246_CR149","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2022","volume":"31","author":"JD Dehondt","year":"2022","unstructured":"Dehondt JD, Holay Q, Brohee S, Mourre H, Hak JF, Osman O, et al. Diabetes is an independent growth factor of ischemic stroke during reperfusion phase leading to poor clinical outcome. J Stroke Cerebrovasc Dis. 2022;31(7):106477. https:\/\/doi.org\/10.1016\/j.jstrokecerebrovasdis.2022.","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"1246_CR150","doi-asserted-by":"publisher","first-page":"159101992413067","DOI":"10.1177\/15910199241306774","volume":"17","author":"G Belge Bilgin","year":"2025","unstructured":"Belge Bilgin G, Bilgin C, Jabal MS, Kobeissi H, Ghozy S, Senol YC, et al. The effects of admission hyperglycemia and diabetes mellitus on mechanical thrombectomy outcomes: a systematic review and meta-analysis. Interv Neuroradiol. 2025;17:15910199241306774. https:\/\/doi.org\/10.1177\/15910199241306774.","journal-title":"Interv Neuroradiol"},{"issue":"1","key":"1246_CR151","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-022-02660-y","volume":"22","author":"Q Gao","year":"2022","unstructured":"Gao Q, Qi P, Wang J, Hu S, Yang X, Fan J, et al. Effects of diabetes mellitus complicated by admission hyperglycemia on clot histological composition and ultrastructure in patients with acute ischemic stroke. BMC Neurol. 2022;22(1):130. https:\/\/doi.org\/10.1186\/s12883-022-02660-y. (Apr 5;).","journal-title":"BMC Neurol"},{"issue":"3","key":"1246_CR152","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1177\/1591019919896940","volume":"26","author":"G Ye","year":"2020","unstructured":"Ye G, Gao Q, Qi P, Wang J, Hu S, Chen K, et al. The role of diabetes mellitus on the thrombus composition in patients with acute ischemic stroke. Interv Neuroradiol. 2020;26(3):329\u201336. https:\/\/doi.org\/10.1177\/1591019919896940.","journal-title":"Interv Neuroradiol"},{"issue":"10","key":"1246_CR153","doi-asserted-by":"publisher","first-page":"e80","DOI":"10.1161\/CIRCRESAHA.119.316288","volume":"126","author":"S Lu","year":"2020","unstructured":"Lu S, Liao Z, Lu X, Katschinski DM, Mercola M, Chen J, et al. Hyperglycemia acutely increases cytosolic reactive oxygen species via O-linked GlcNAcylation and CaMKII activation in mouse ventricular myocytes. Circ Res. 2020;126(10):e80\u201396. https:\/\/doi.org\/10.1161\/CIRCRESAHA.119.316288.","journal-title":"Circ Res"},{"issue":"6","key":"1246_CR154","doi-asserted-by":"publisher","first-page":"472","DOI":"10.5603\/PJNNS.a2022.0063","volume":"56","author":"A Lasek-Bal","year":"2022","unstructured":"Lasek-Bal A, \u017bak A, Binek \u0141, Student S, Cie\u015blik A, Bal W, et al. Relevance of admission hyperglycaemia and diabetes mellitus to efficacy and safety of mechanical thrombectomy in stroke patients. Neurol Neurochir Pol. 2022;56(6):472\u20139. https:\/\/doi.org\/10.5603\/PJNNS.a2022.0063.","journal-title":"Neurol Neurochir Pol"},{"issue":"5","key":"1246_CR155","doi-asserted-by":"publisher","DOI":"10.3390\/life12050632","volume":"12","author":"PJ Kalmar","year":"2022","unstructured":"Kalmar PJ, Tarkanyi G, Karadi ZN, Szapary L, Bosnyak E. The impact of diabetes mellitus and admission hyperglycemia on clinical outcomes after recanalization therapies for acute ischemic stroke: STAY ALIVE National Prospective Registry. Life. 2022;12(5):632. https:\/\/doi.org\/10.3390\/life12050632.","journal-title":"Life"},{"issue":"4","key":"1246_CR156","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1136\/neurintsurg-2021-018485","volume":"15","author":"NK Bains","year":"2023","unstructured":"Bains NK, Huang W, French BR, Siddiq F, Gomez CR, Qureshi AI. Hyperglycemic control in acute ischemic stroke patients undergoing endovascular treatment: post hoc analysis of the Stroke Hyperglycemia Insulin Network Effort trial. J Neurointerv Surg. 2023;15(4):370\u20134. https:\/\/doi.org\/10.1136\/neurintsurg-2021-018485.","journal-title":"J Neurointerv Surg"},{"issue":"9","key":"1246_CR157","doi-asserted-by":"publisher","first-page":"2599","DOI":"10.1161\/STROKEAHA.114.006070","volume":"45","author":"L Friberg","year":"2014","unstructured":"Friberg L, Rosenqvist M, Lindgren A, Ter\u00e9nt A, Norrving B, Asplund K. High prevalence of atrial fibrillation among patients with ischemic stroke. Stroke. 2014;45(9):2599\u2013605. https:\/\/doi.org\/10.1161\/STROKEAHA.114.006070.","journal-title":"Stroke"},{"issue":"2","key":"1246_CR158","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1161\/STROKEAHA.113.003433","volume":"45","author":"A Kishore","year":"2014","unstructured":"Kishore A, Vail A, Majid A, Dawson J, Lees KR, Tyrrell PJ, et al. Detection of atrial fibrillation after ischemic stroke or transient ischemic attack: a systematic review and meta-analysis. Stroke. 2014;45(2):520\u20136. https:\/\/doi.org\/10.1161\/STROKEAHA.113.003433.","journal-title":"Stroke"},{"issue":"1","key":"1246_CR159","doi-asserted-by":"publisher","first-page":"e2249993","DOI":"10.1001\/jamanetworkopen.2022.49993","volume":"6","author":"H Kobeissi","year":"2023","unstructured":"Kobeissi H, Ghozy S, Seymour T, Gupta R, Bilgin C, Kadirvel R, et al. Outcomes of patients with atrial fibrillation following thrombectomy for stroke: a systematic review and meta -analysis. JAMA Netw Open. 2023;6(1):e2249993. https:\/\/doi.org\/10.1001\/jamanetworkopen.2022.49993.","journal-title":"JAMA Netw Open"},{"issue":"4","key":"1246_CR160","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1111\/ijs.12007","volume":"10","author":"HT Tu","year":"2015","unstructured":"Tu HT, Campbell BC, Christensen S, Desmond PM, De Silva DA, Parsons MW, et al. Worse stroke outcome in atrial fibrillation is explained by more severe hypoperfusion, infarct growth, and hemorrhagic transformation. Int J Stroke. 2015;10(4):534\u201340. https:\/\/doi.org\/10.1111\/ijs.12007.","journal-title":"Int J Stroke"},{"issue":"7","key":"1246_CR161","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1136\/jnis-2023-020512","volume":"16","author":"P Pillai","year":"2024","unstructured":"Pillai P, Bush SJ, Kusuma Y, Churilov L, Dowling RJ, Luu VD, et al. Atrial fibrillation is associated with higher first pass effect following thrombectomy for large vessel occlusion. J Neurointerv Surg. 2024;16(7):652\u20136. https:\/\/doi.org\/10.1136\/jnis-2023-020512.","journal-title":"J Neurointerv Surg"},{"issue":"3","key":"1246_CR162","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1177\/2396987320923447","volume":"5","author":"JA Smaal","year":"2020","unstructured":"Smaal JA, de Ridder IR, Heshmatollah A, van Zwam WH, Dippel D, Majoie CB, et al. Effect of atrial fibrillation on endovascular thrombectomy for acute ischemic stroke. A meta-analysis of individual patient data from six randomised trials: results from the HERMES collaboration. Eur Stroke J. 2020;5(3):245\u201351. https:\/\/doi.org\/10.1177\/2396987320923447.","journal-title":"Eur Stroke J"},{"issue":"10","key":"1246_CR163","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1136\/neurintsurg-2020-016720","volume":"13","author":"F Akbik","year":"2021","unstructured":"Akbik F, Alawieh A, Cawley CM, Howard BM, Tong FC, Nahab F, et al. Differential effect of mechanical thrombectomy and intravenous thrombolysis in atrial fibrillation associated stroke. J Neurointerv Surg. 2021;13(10):883\u20138. https:\/\/doi.org\/10.1136\/neurintsurg-2020-016720.","journal-title":"J Neurointerv Surg."},{"issue":"24","key":"1246_CR164","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.123.031733","volume":"12","author":"W Zheng","year":"2023","unstructured":"Zheng W, Tang Y, Lin H, Huang H, Lei H, Lin H, et al. Atrial fibrillation and clinical outcomes of endovascular thrombectomy for acute ischemic stroke: a meta-analysis of adjusted effect estimates. J Am Heart Assoc. 2023;12(24):e031733. https:\/\/doi.org\/10.1161\/JAHA.123.031733.","journal-title":"J Am Heart Assoc"},{"issue":"12","key":"1246_CR165","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13123469","volume":"13","author":"M Boro\u0144czyk","year":"2024","unstructured":"Boro\u0144czyk M, Ku\u017aniak M, Boro\u0144czyk A, Bara\u0144ski K, Hawrot-Kawecka A, Lasek-Bal A. Chronic kidney disease increases mortality and reduces the chance of a favorable outcome in stroke patients treated with mechanical thrombectomy-single-center study. J Clin Med. 2024;13(12):3469. https:\/\/doi.org\/10.3390\/jcm13123469.","journal-title":"J Clin Med"},{"issue":"4","key":"1246_CR166","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2020.104665","volume":"29","author":"LJ Sutherland","year":"2020","unstructured":"Sutherland LJ, Diprose WK, Wang MTM, Barber PA. Chronic kidney disease and outcome following endovascular thrombectomy for acute ischemic stroke. J Stroke Cerebrovasc Dis. 2020;29(4):104665. https:\/\/doi.org\/10.1016\/j.jstrokecerebrovasdis.2020.104665.","journal-title":"J Stroke Cerebrovasc Dis"},{"issue":"1","key":"1246_CR167","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1007\/s12975-016-0499-x","volume":"8","author":"WL Lau","year":"2017","unstructured":"Lau WL, Huisa BN, Fisher M. The cerebrovascular-chronic kidney disease connection: perspectives and mechanisms. Transl Stroke Res. 2017;8(1):67\u201376. https:\/\/doi.org\/10.1007\/s12975-016-0499-x.","journal-title":"Transl Stroke Res"},{"issue":"1","key":"1246_CR168","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1111\/nep.14251","volume":"29","author":"K Rajesh","year":"2024","unstructured":"Rajesh K, Spring KJ, Beran RG, Bhaskar SMM. Chronic kidney disease prevalence and clinical outcomes in anterior circulation acute ischemic stroke patients with reperfusion therapy: a meta-analysis. Nephrology (Carlton). 2024;29(1):21\u201333. https:\/\/doi.org\/10.1111\/nep.14251.","journal-title":"Nephrology (Carlton)"},{"issue":"e3","key":"1246_CR169","doi-asserted-by":"publisher","first-page":"e337","DOI":"10.1136\/jnis-2022-019666","volume":"15","author":"KW Chen","year":"2023","unstructured":"Chen KW, Chen CH, Lin YH, Lee CW, Tsai KC, Tsai LK, et al. Outcome of endovascular thrombectomy in patients with end-stage renal disease undergoing dialysis. J Neurointerv Surg. 2023;15(e3):e337\u201342. https:\/\/doi.org\/10.1136\/jnis-2022-019666.","journal-title":"J Neurointerv Surg"},{"issue":"23","key":"1246_CR170","doi-asserted-by":"publisher","first-page":"e2583","DOI":"10.1212\/WNL.0000000000201208","volume":"99","author":"SD Shapiro","year":"2022","unstructured":"Shapiro SD, Vazquez S, Das A, Dominguez JF, Kamal H, Chong J, et al. Investigating outcomes post-endovascular thrombectomy in acute stroke patients with cancer. Neurology. 2022;99(23):e2583\u201392. https:\/\/doi.org\/10.1212\/WNL.0000000000201208.","journal-title":"Neurology"},{"issue":"1","key":"1246_CR171","doi-asserted-by":"publisher","first-page":"95","DOI":"10.5114\/aic.2024.137433","volume":"20","author":"E W\u0142odarczyk","year":"2024","unstructured":"W\u0142odarczyk E, Wrona P, Homa T, Sobolewska M, Wr\u00f3bel D, Rolkiewicz D, et al. Long-term outcomes of mechanical thrombectomy in acute ischaemic stroke patients with concomitant malignancy. Adv Interv Cardiol. 2024;20(1):95\u2013102. https:\/\/doi.org\/10.5114\/aic.2024.137433.","journal-title":"Adv Interv Cardiol"},{"issue":"10","key":"1246_CR172","doi-asserted-by":"publisher","first-page":"e993","DOI":"10.1212\/WNL.0000000000013316","volume":"98","author":"MA Verschoof","year":"2022","unstructured":"Verschoof MA, Groot AE, de Bruijn SFTM, Roozenbeek B, van der Worp HB, Dippel DWJ, et al. Clinical outcome after endovascular treatment in patients with active cancer and ischemic stroke: a MR CLEAN Registry Substudy. Neurology. 2022;98(10):e993\u20131001. https:\/\/doi.org\/10.1212\/WNL.0000000000013316.","journal-title":"Neurology"},{"key":"1246_CR173","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.992825","volume":"13","author":"L Duan","year":"2022","unstructured":"Duan L, Fu Z, Zhao H, Song C, Tian Q, Dmytriw AA, et al. Outcomes after endovascular thrombectomy for acute ischemic stroke patients with active cancer: a systematic review and meta-analysis. Front Neurol. 2022;13:992825. https:\/\/doi.org\/10.3389\/fneur.2022.992825.","journal-title":"Front Neurol"},{"issue":"1","key":"1246_CR174","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1258\/RSMSMJ.53.1.44","volume":"53","author":"TJ Quinn","year":"2008","unstructured":"Quinn TJ, Dawson J, Walters M. Dr john Rankin; his life, legacy and the 50th anniversary of the Rankin Stroke Scale. Scott Med J. 2008;53(1):44\u20137. https:\/\/doi.org\/10.1258\/RSMSMJ.53.1.44.","journal-title":"Scott Med J"},{"issue":"12","key":"1246_CR175","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1136\/jnnp.54.12.1044","volume":"54","author":"B Farrell","year":"1991","unstructured":"Farrell B, Godwin J, Richards S, Warlow C. The United Kingdom transient ischaemic attack (UK-TIA) aspirin trial: final results. J Neurol Neurosurg Psychiatry. 1991;54(12):1044\u201354. https:\/\/doi.org\/10.1136\/jnnp.54.12.1044.","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"8","key":"1246_CR176","doi-asserted-by":"publisher","first-page":"e8","DOI":"10.1136\/neurintsurg-2018-014569","volume":"15","author":"G Turc","year":"2023","unstructured":"Turc G, Bhogal P, Fischer U, Khatri P, Lobotesis K, Mazighi M, et al. European Stroke Organisation (ESO). J Neurointerv Surg. 2023;15(8):e8\u2013e8. https:\/\/doi.org\/10.1136\/neurintsurg-2018-014569.","journal-title":"J Neurointerv Surg"},{"issue":"6","key":"1246_CR177","doi-asserted-by":"publisher","first-page":"1642","DOI":"10.1161\/STROKEAHA.124.050299","volume":"56","author":"J Vuong","year":"2025","unstructured":"Vuong J, Phan TG, Yan B, Mitchell PJ, Davis SM, Koga M, et al. Stay-home: endovascular thrombectomy for patients with prestroke disability. Stroke. 2025;56(6):1642\u20135. https:\/\/doi.org\/10.1161\/STROKEAHA.124.050299.","journal-title":"Stroke"},{"issue":"3","key":"1246_CR178","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1136\/neurintsurg-2021-018428","volume":"15","author":"RV McDonough","year":"2023","unstructured":"McDonough RV, Ospel JM, Majoie CBLM, Saver JL, White P, Dippel DWJ, et al. Clinical outcome of patients with mild pre-stroke morbidity following endovascular treatment: a HERMES substudy. J Neurointerv Surg. 2023;15(3):214\u201320. https:\/\/doi.org\/10.1136\/neurintsurg-2021-018428.","journal-title":"J Neurointerv Surg"},{"issue":"2","key":"1246_CR179","doi-asserted-by":"publisher","first-page":"283","DOI":"10.3174\/ajnr.A5920","volume":"40","author":"F Seker","year":"2019","unstructured":"Seker F, Pfaff J, Sch\u00f6nenberger S, Herweh C, Nagel S, Ringleb PA, et al. Clinical outcome after thrombectomy in patients with stroke with premorbid modified rankin scale scores of 3 and 4: a cohort study with 136 patients. AJNR Am J Neuroradiol. 2019;40(2):283\u20136. https:\/\/doi.org\/10.3174\/ajnr.A5920.","journal-title":"AJNR Am J Neuroradiol"},{"issue":"4","key":"1246_CR180","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1161\/STROKEAHA.124.048997","volume":"56","author":"A Naldi","year":"2025","unstructured":"Naldi A, D\u2019Agata F, Pracucci G, Saia V, Cavallo R, Castellano D, et al. Mechanical thrombectomy in prestroke disability: data from the Italian Endovascular Stroke Registry. Stroke. 2025;56(4):850\u20137. https:\/\/doi.org\/10.1161\/STROKEAHA.124.048997.","journal-title":"Stroke"},{"issue":"1","key":"1246_CR181","doi-asserted-by":"publisher","first-page":"e8","DOI":"10.1161\/STROKEAHA.124.048424","volume":"56","author":"NR Evans","year":"2025","unstructured":"Evans NR, Fearon P, Beishon L, Pinho J, Quinn TJ. The importance of frailty in stroke and how to measure it. Stroke. 2025;56(1):e8\u201311. https:\/\/doi.org\/10.1161\/STROKEAHA.124.048424.","journal-title":"Stroke"},{"issue":"3","key":"1246_CR182","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1177\/17474930211034331","volume":"17","author":"NR Evans","year":"2022","unstructured":"Evans NR, Todd OM, Minhas JS, Fearon P, Harston GW, Mant J, et al. Frailty and cerebrovascular disease: concepts and clinical implications for stroke medicine. Int J Stroke. 2022;17(3):251\u20139. https:\/\/doi.org\/10.1177\/17474930211034331.","journal-title":"Int J Stroke"},{"key":"1246_CR183","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2024.1347476","volume":"15","author":"J Li","year":"2024","unstructured":"Li J, Wan J, Wang H. Role of frailty in predicting outcomes after stroke: a systematic review and meta-analysis. Front Psychiatry. 2024;15:1347476. https:\/\/doi.org\/10.3389\/fpsyt.2024.1347476.","journal-title":"Front Psychiatry"},{"issue":"4","key":"1246_CR184","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1093\/ageing\/afaa004","volume":"49","author":"NR Evans","year":"2020","unstructured":"Evans NR, Wall J, To B, Wallis SJ, Romero-Ortuno R, Warburton EA. Clinical frailty independently predicts early mortality after ischaemic stroke. Age Ageing. 2020;49(4):588\u201391. https:\/\/doi.org\/10.1093\/ageing\/afaa004.","journal-title":"Age Ageing"},{"key":"1246_CR185","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.nut.2019.04.011","volume":"66","author":"M Nozoe","year":"2019","unstructured":"Nozoe M, Kanai M, Kubo H, Yamamoto M, Shimada S, Mase K. Prestroke sarcopenia and functional outcomes in elderly patients who have had an acute stroke: a prospective cohort study. Nutrition. 2019;66:44\u20137. https:\/\/doi.org\/10.1016\/j.nut.2019.04.011.","journal-title":"Nutrition"},{"issue":"3","key":"1246_CR186","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1016\/j.jamda.2019.12.012","volume":"21","author":"LK Chen","year":"2020","unstructured":"Chen LK, Woo J, Assantachai P, Auyeung TW, Chou MY, Iijima K, et al. Asian Working Group for sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment. J Am Med Dir Assoc. 2020;21(3):300-307.e2. https:\/\/doi.org\/10.1016\/j.jamda.2019.12.012.","journal-title":"J Am Med Dir Assoc"},{"issue":"1","key":"1246_CR187","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-025-04136-1","volume":"25","author":"R Chen","year":"2025","unstructured":"Chen R, Liu Z, Liao R, Liang H, Hu C, Zhang X, et al. The effect of sarcopenia on prognosis in patients with mild acute ischemic stroke: a prospective cohort study. BMC Neurol. 2025;25(1):130. https:\/\/doi.org\/10.1186\/s12883-025-04136-1.","journal-title":"BMC Neurol"},{"key":"1246_CR188","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2022.101789","volume":"84","author":"D Kaskirbayeva","year":"2023","unstructured":"Kaskirbayeva D, West R, Jaafari H, King N, Howdon D, Shuweihdi F, et al. Progression of frailty as measured by a cumulative deficit index: a systematic review. Ageing Res Rev. 2023;84:101789. https:\/\/doi.org\/10.1016\/j.arr.2022.101789.","journal-title":"Ageing Res Rev"},{"issue":"10","key":"1246_CR189","doi-asserted-by":"publisher","first-page":"1817","DOI":"10.1161\/01.str.27.10.1817","volume":"27","author":"KW Muir","year":"1996","unstructured":"Muir KW, Weir CJ, Murray GD, Povey C, Lees KR. Comparison of neurological scales and scoring systems for acute stroke prognosis. Stroke. 1996;27(10):1817\u201320. https:\/\/doi.org\/10.1161\/01.str.27.10.1817.","journal-title":"Stroke"},{"issue":"6","key":"1246_CR190","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1136\/neurintsurg-2018-014289","volume":"11","author":"A Alawieh","year":"2019","unstructured":"Alawieh A, Starke RM, Chatterjee AR, Turk A, De Leacy R, Rai AT, et al. Outcomes of endovascular thrombectomy in the elderly: a \u2018real-world\u2019 multicenter study. J Neurointerv Surg. 2019;11(6):545\u201353. https:\/\/doi.org\/10.1136\/neurintsurg-2018-014289.","journal-title":"J Neurointerv Surg"},{"issue":"7","key":"1246_CR191","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.3174\/ajnr.A3855","volume":"35","author":"MA Almekhlafi","year":"2014","unstructured":"Almekhlafi MA, Davalos A, Bonafe A, Chapot R, Gralla J, Pereira VM, et al. Impact of age and baseline NIHSS scores on clinical outcomes in the mechanical thrombectomy using solitaire FR in acute ischemic stroke study. AJNR Am J Neuroradiol. 2014;35(7):1337\u201340. https:\/\/doi.org\/10.3174\/ajnr.A3855.","journal-title":"AJNR Am J Neuroradiol"},{"issue":"1","key":"1246_CR192","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1159\/000015889","volume":"9","author":"JC Sharma","year":"1999","unstructured":"Sharma JC, Fletcher S, Vassallo M. Strokes in the elderly - higher acute and 3-month mortality - an explanation. Cerebrovasc Dis. 1999;9(1):2\u20139. https:\/\/doi.org\/10.1159\/000015889.","journal-title":"Cerebrovasc Dis"},{"issue":"1","key":"1246_CR193","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1212\/WNL.0b013e31827b1ace","volume":"80","author":"G Saposnik","year":"2013","unstructured":"Saposnik G, Guzik AK, Reeves M, Ovbiagele B, Johnston SC. Stroke prognostication using age and NIH stroke scale: SPAN-100. Neurology. 2013;80(1):21\u20138. https:\/\/doi.org\/10.1212\/WNL.0b013e31827b1ace.","journal-title":"Neurology"},{"issue":"9","key":"1246_CR194","doi-asserted-by":"publisher","first-page":"2839","DOI":"10.1161\/STROKEAHA.120.032364","volume":"52","author":"JM Ospel","year":"2021","unstructured":"Ospel JM, Brown S, Kappelhof M, van Zwam W, Jovin T, Roy D, et al. Comparing the prognostic impact of age and baseline National Institutes of Health Stroke Scale in acute stroke due to large vessel occlusion. Stroke. 2021;52(9):2839\u201345. https:\/\/doi.org\/10.1161\/STROKEAHA.120.032364.","journal-title":"Stroke"},{"issue":"6","key":"1246_CR195","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2021.10805","volume":"22","author":"NO Pop","year":"2021","unstructured":"Pop NO, Tit DM, Diaconu CC, Munteanu MA, Babes EE, Stoicescu M, et al. The Alberta stroke program early CT score (ASPECTS): a predictor of mortality in acute ischemic stroke. Exp Ther Med. 2021;22(6):1371. https:\/\/doi.org\/10.3892\/etm.2021.10805.","journal-title":"Exp Ther Med"},{"issue":"2021","key":"1246_CR196","doi-asserted-by":"publisher","first-page":"5935170","DOI":"10.1155\/2021\/5935170.s","volume":"29","author":"A Esmael","year":"2021","unstructured":"Esmael A, Elsherief M, Eltoukhy K. Predictive Value of the Alberta Stroke Program Early CT Score (ASPECTS) in the outcome of the acute ischemic stroke and its correlation with stroke subtypes, NIHSS, and cognitive impairment. Stroke Res Treat. 2021;29(2021):5935170. https:\/\/doi.org\/10.1155\/2021\/5935170.s.","journal-title":"Stroke Res Treat."},{"issue":"7","key":"1246_CR197","doi-asserted-by":"publisher","first-page":"2220","DOI":"10.1161\/STROKEAHA.120.032430","volume":"52","author":"OO Zaidat","year":"2021","unstructured":"Zaidat OO, Liebeskind DS, Jadhav AP, Ortega-Gutierrez S, Nguyen TN, Haussen DC, et al. Impact of age and Alberta Stroke Program Early Computed Tomography Score 0 to 5 on mechanical thrombectomy outcomes: analysis from the STRATIS Registry. Stroke. 2021;52(7):2220\u20138. https:\/\/doi.org\/10.1161\/STROKEAHA.120.032430.","journal-title":"Stroke"},{"issue":"10","key":"1246_CR198","doi-asserted-by":"publisher","first-page":"3109","DOI":"10.1161\/STROKEAHA.120.033101","volume":"52","author":"L Meyer","year":"2021","unstructured":"Meyer L, Bechstein M, Bester M, Hanning U, Brekenfeld C, Flottmann F, et al. Thrombectomy in extensive stroke may not be beneficial and is associated with increased risk for hemorrhage. Stroke. 2021;52(10):3109\u201317. https:\/\/doi.org\/10.1161\/STROKEAHA.120.033101.","journal-title":"Stroke"},{"issue":"1","key":"1246_CR199","doi-asserted-by":"publisher","first-page":"90","DOI":"10.3174\/ajnr.A4968","volume":"38","author":"C Dargazanli","year":"2017","unstructured":"Dargazanli C, Consoli A, Barral M, Labreuche J, Redjem H, Ciccio G, et al. Impact of modified TICI 3 versus modified TICI 2b reperfusion score to predict good outcome following endovascular therapy. AJNR Am J Neuroradiol. 2017;38(1):90\u20136. https:\/\/doi.org\/10.3174\/ajnr.A4968.","journal-title":"AJNR Am J Neuroradiol"},{"issue":"2","key":"1246_CR200","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1007\/s00062-021-01048-8","volume":"32","author":"F Flottmann","year":"2022","unstructured":"Flottmann F, van Horn N, Maros ME, McDonough R, Deb-Chatterji M, Alegiani A, et al. Early TICI 2b or late TICI 3\u2014is perfect the enemy of good? Clin Neuroradiol. 2022;32(2):353\u201360. https:\/\/doi.org\/10.1007\/s00062-021-01048-8.","journal-title":"Clin Neuroradiol"},{"issue":"9","key":"1246_CR201","doi-asserted-by":"publisher","first-page":"878","DOI":"10.1136\/jnis-2023-020411","volume":"16","author":"N Rex","year":"2024","unstructured":"Rex N, Ospel JM, Brown SB, McDonough RV, Kashani N, Hill MD, et al. Endovascular therapy in acute ischemic stroke with poor reperfusion is associated with worse outcomes compared with best medical management: a HERMES substudy. J Neurointerv Surg. 2024;16(9):878\u201383. https:\/\/doi.org\/10.1136\/jnis-2023-020411.","journal-title":"J Neurointerv Surg"},{"issue":"6","key":"1246_CR202","doi-asserted-by":"publisher","first-page":"2096","DOI":"10.14336\/AD.2023.0321-1","volume":"14","author":"G Deng","year":"2023","unstructured":"Deng G, Chu YH, Xiao J, Shang K, Zhou LQ, Qin C, et al. Risk factors, pathophysiologic mechanisms, and potential treatment strategies of futile recanalization after endovascular therapy in acute ischemic stroke. Aging Dis. 2023;14(6):2096\u2013112. https:\/\/doi.org\/10.14336\/AD.2023.0321-1.","journal-title":"Aging Dis"},{"issue":"10","key":"1246_CR203","doi-asserted-by":"publisher","DOI":"10.3390\/life13101965","volume":"13","author":"H Shen","year":"2023","unstructured":"Shen H, Killingsworth MC, Bhaskar SMM. Comprehensive meta-analysis of futile recanalization in acute ischemic stroke patients undergoing endovascular thrombectomy: prevalence, factors, and clinical outcomes. Life (Basel). 2023;13(10):1965. https:\/\/doi.org\/10.3390\/life13101965.","journal-title":"Life (Basel)"},{"issue":"8","key":"1246_CR204","doi-asserted-by":"publisher","first-page":"4925","DOI":"10.1007\/s00415-024-12428-8","volume":"271","author":"L D'Anna","year":"2024","unstructured":"D\u2019Anna L, Merlino G, Romoli M, Zhang L, Del Regno C, Aggour M, et al. Predictors of futile recanalization in nonagenarians treated with mechanical thrombectomy: a multi-center observational study. J Neurol. 2024;271(8):4925\u201332. https:\/\/doi.org\/10.1007\/s00415-024-12428-8.","journal-title":"J Neurol"},{"issue":"12","key":"1246_CR205","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1001\/jama.2016.13647","volume":"316","author":"JL Saver","year":"2016","unstructured":"Saver JL, Goyal M, van der Lugt A, Menon BK, Majoie CB, Dippel DW, et al. Time to treatment with endovascular thrombectomy and outcomes from ischemic stroke: a meta-analysis. JAMA. 2016;316(12):1279\u201388. https:\/\/doi.org\/10.1001\/jama.2016.13647.","journal-title":"JAMA"},{"issue":"6","key":"1246_CR206","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1177\/1747493018778713","volume":"13","author":"D Sacks","year":"2018","unstructured":"Sacks D, Baxter B, Campbell BCV, Carpenter JS, Cognard C, Dippel D, et al. Multisociety Consensus quality improvement revised consensus statement for endovascular therapy of acute ischemic stroke. Int J Stroke. 2018;13(6):612\u201332. https:\/\/doi.org\/10.1177\/1747493018778713.","journal-title":"Int J Stroke"},{"issue":"2","key":"1246_CR207","doi-asserted-by":"publisher","first-page":"71","DOI":"10.5469\/neuroint.2025.00178","volume":"20","author":"EJ Lee","year":"2025","unstructured":"Lee EJ, Jeong HY, Kim J, Park NH, Kang MK, Lee D, et al. Procedure time of endovascular thrombectomy as performance measure of acute stroke treatment. Neurointervention. 2025;20(2):71\u201381. https:\/\/doi.org\/10.5469\/neuroint.2025.00178.","journal-title":"Neurointervention"},{"issue":"5","key":"1246_CR208","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1007\/s00234-020-02586-7","volume":"63","author":"X Bai","year":"2021","unstructured":"Bai X, Zhang X, Yang W, Zhang Y, Wang T, Xu R, et al. Influence of first-pass effect on recanalization outcomes in the era of mechanical thrombectomy: a systemic review and meta-analysis. Neuroradiology. 2021;63(5):795\u2013807. https:\/\/doi.org\/10.1007\/s00234-020-02586-7.","journal-title":"Neuroradiology"},{"issue":"13","key":"1246_CR209","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1212\/WNL.0b013e3181b9c847","volume":"73","author":"P Khatri","year":"2009","unstructured":"Khatri P, Abruzzo T, Yeatts SD, Nichols C, Broderick JP, Tomsick TA, et al. Good clinical outcome after ischemic stroke with successful revascularization is time-dependent. Neurology. 2009;73(13):1066\u201372. https:\/\/doi.org\/10.1212\/WNL.0b013e3181b9c847.","journal-title":"Neurology"},{"issue":"1","key":"1246_CR210","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1161\/STROKEAHA.119.026437","volume":"51","author":"WG Tekle","year":"2020","unstructured":"Tekle WG, Hassan AE, Jadhav AP, Haussen DC, Budzik RF, Bonafe A, et al. Impact of periprocedural and technical factors and patient characteristics on revascularization and outcome in the DAWN trial. Stroke. 2020;51(1):247\u201353. https:\/\/doi.org\/10.1161\/STROKEAHA.119.026437.","journal-title":"Stroke"},{"issue":"7","key":"1246_CR211","doi-asserted-by":"publisher","first-page":"1781","DOI":"10.1161\/STROKEAHA.119.025088","volume":"50","author":"\u00c1 Garc\u00eda-Tornel","year":"2019","unstructured":"Garc\u00eda-Tornel \u00c1, Requena M, Rubiera M, Muchada M, Pagola J, Rodriguez-Luna D, et al. When to stop. Stroke. 2019;50(7):1781\u20138. https:\/\/doi.org\/10.1161\/STROKEAHA.119.025088.","journal-title":"Stroke"},{"issue":"7","key":"1246_CR212","doi-asserted-by":"publisher","first-page":"2036","DOI":"10.1161\/STROKEAHA.120.028963","volume":"51","author":"M Cappellari","year":"2020","unstructured":"Cappellari M, Pracucci G, Forlivesi S, Saia V, Nappini S, Nencini P, et al. General anesthesia versus conscious sedation and local anesthesia during thrombectomy for acute ischemic stroke. Stroke. 2020;51(7):2036\u201344. https:\/\/doi.org\/10.1161\/STROKEAHA.120.028963.","journal-title":"Stroke"},{"issue":"2","key":"1246_CR213","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1161\/STROKEAHA.116.015343","volume":"48","author":"K Bekelis","year":"2017","unstructured":"Bekelis K, Missios S, MacKenzie TA, Tjoumakaris S, Jabbour P. Anesthesia technique and outcomes of mechanical thrombectomy in patients with acute ischemic stroke. Stroke. 2017;48(2):361\u20136. https:\/\/doi.org\/10.1161\/STROKEAHA.116.015343.","journal-title":"Stroke"},{"issue":"16","key":"1246_CR214","doi-asserted-by":"publisher","first-page":"e1655","DOI":"10.1212\/WNL.0000000000207066","volume":"100","author":"D Campbell","year":"2023","unstructured":"Campbell D, Butler E, Campbell RB, Ho J, Barber PA. General anesthesia compared with non-GA in endovascular thrombectomy for ischemic stroke: a systematic review and meta-analysis of randomized controlled trials. Neurology. 2023;100(16):e1655\u201363. https:\/\/doi.org\/10.1212\/WNL.0000000000207066.","journal-title":"Neurology"},{"issue":"7","key":"1246_CR215","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1177\/17474930241228956","volume":"19","author":"Y Jia","year":"2024","unstructured":"Jia Y, Feng Y, Ma Y, Feng G, Xu N, Li M, et al. Type of anesthesia for endovascular therapy in acute ischemic stroke: a literature review and meta-analysis. Int J Stroke. 2024;19(7):735\u201346. https:\/\/doi.org\/10.1177\/17474930241228956.","journal-title":"Int J Stroke"},{"key":"1246_CR216","doi-asserted-by":"publisher","DOI":"10.1177\/23969873241293009","author":"V Levee","year":"2024","unstructured":"Levee V, Valente M, Bax F, Zhang L, Sacco S, Foschi M, et al. Outcomes of different anesthesia techniques in nonagenarians treated with mechanical thrombectomy for anterior circulation large vessel occlusion: an inverse probability weighting analysis. Eur Stroke J. 2024. https:\/\/doi.org\/10.1177\/23969873241293009.","journal-title":"Eur Stroke J"},{"key":"1246_CR217","doi-asserted-by":"publisher","unstructured":"Sch\u00f6nenberger S, Hend\u00e9n PL, Simonsen CZ, Uhlmann L, Klose C, Pfaff JAR, Yoo AJ, S\u00f8rensen LH, Ringleb PA, Wick W, Kieser M, M\u00f6hlenbruch MA, Rasmussen M, Rentzos A, B\u00f6sel J. Association of general anesthesia vs procedural sedation with functional outcome among patients with acute ischemic stroke undergoing thrombectomy: a systematic review and meta-analysis. JAMA. 2019;322(13):1283\u201393. https:\/\/doi.org\/10.1001\/jama.2019.11455. Erratum in: JAMA. 2019;322(24):2445. https:\/\/doi.org\/10.1001\/jama.2019.20482.","DOI":"10.1001\/jama.2019.11455"},{"issue":"4","key":"1246_CR218","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1097\/ANA.0000000000000661","volume":"33","author":"DA Rusy","year":"2021","unstructured":"Rusy DA, Hofer A, Rasmussen M, Paisansathan C, Sharma D. Assessment of anesthesia practice patterns for endovascular therapy for acute ischemic stroke: a society for neuroscience in anesthesiology and critical care (SNACC) member survey. J Neurosurg Anesthesiol. 2021;33(4):343\u20136. https:\/\/doi.org\/10.1097\/ANA.0000000000000661.","journal-title":"J Neurosurg Anesthesiol"},{"key":"1246_CR219","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.jocn.2023.08.007","volume":"116","author":"V Byrappa","year":"2023","unstructured":"Byrappa V, Manohara N, John S, Lobo FA, Lamperti M. Factors influencing the need for emergent conversion to general anesthesia during mechanical thrombectomy in acute anterior circulation stroke \u2013 a retrospective observational study. J Clin Neurosci. 2023;116:20\u20136. https:\/\/doi.org\/10.1016\/j.jocn.2023.08.007.","journal-title":"J Clin Neurosci"},{"key":"1246_CR220","doi-asserted-by":"publisher","first-page":"1869","DOI":"10.1161\/STROKEAHA.116.016225","volume":"48","author":"MJHL Mulder","year":"2017","unstructured":"Mulder MJHL, Ergezen S, Lingsma HF, Berkhemer OA, Fransen PSS, Beumer D, et al. Baseline blood pressure effect on the benefit and safety of intra-arterial treatment in MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands). Stroke. 2017;48:1869\u201376. https:\/\/doi.org\/10.1161\/STROKEAHA.116.016225.","journal-title":"Stroke"},{"key":"1246_CR221","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1136\/neurintsurg-2016-012386","volume":"9","author":"N Goyal","year":"2017","unstructured":"Goyal N, Tsivgoulis G, Iftikhar S, Khorchid Y, Fawad Ishfaq M, Doss VT, et al. Admission systolic blood pressure and outcomes in large vessel occlusion strokes treated with endovascular treatment. J Neurointerv Surg. 2017;9:451\u20134. https:\/\/doi.org\/10.1136\/neurintsurg-2016-012386.","journal-title":"J Neurointerv Surg."},{"issue":"5","key":"1246_CR222","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1001\/jamaneurol.2019.4838","volume":"77","author":"M Rasmussen","year":"2020","unstructured":"Rasmussen M, Sch\u00f6nenberger S, Hend\u00e8n PL, Valentin JB, Espelund US, S\u00f8rensen LH, et al. Blood pressure thresholds and neurologic outcomes after endovascular therapy for acute ischemic stroke: an analysis of individual patient data from 3 randomized clinical trials. JAMA Neurol. 2020;77(5):622\u201331. https:\/\/doi.org\/10.1001\/jamaneurol.2019.4838.","journal-title":"JAMA Neurol"},{"issue":"12","key":"1246_CR223","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1136\/jnis-2023-020899","volume":"16","author":"M Galecio-Castillo","year":"2024","unstructured":"Galecio-Castillo M, Quispe-Orozco D, Farooqui M, Dajles A, Vivanco-Suarez J, Rodriguez-Calienes A, et al. Association between intraprocedural drops in blood pressure and infarct growth rate patterns after acute large-vessel occlusions. J Neurointerv Surg. 2024;16(12):1275\u201381. https:\/\/doi.org\/10.1136\/jnis-2023-020899.","journal-title":"J Neurointerv Surg"},{"issue":"3","key":"1246_CR224","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1007\/s12028-021-01229-w","volume":"35","author":"M Chen","year":"2021","unstructured":"Chen M, Kronsteiner D, Pfaff J, Schieber S, J\u00e4ger L, Bendszus M, et al. Hemodynamic status during endovascular stroke treatment: association of blood pressure with functional outcome. Neurocrit Care. 2021;35(3):825\u201334. https:\/\/doi.org\/10.1007\/s12028-021-01229-w.","journal-title":"Neurocrit Care"},{"key":"1246_CR225","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1097\/ANA.0000000000000042","volume":"26","author":"PO Talke","year":"2014","unstructured":"Talke PO, Sharma D, Heyer EJ, et al. Society for Neuroscience in Anesthesiology and Critical Care expert consensus statement: anesthetic management of endovascular treatment for acute ischemic stroke. J Neurosurg Anesthesiol. 2014;26:95\u2013108. https:\/\/doi.org\/10.1097\/ANA.0000000000000042.","journal-title":"J Neurosurg Anesthesiol"},{"issue":"11","key":"1246_CR226","doi-asserted-by":"publisher","first-page":"2755","DOI":"10.1161\/STROKEAHA.123.044062","volume":"54","author":"M Chen","year":"2023","unstructured":"Chen M, Meis J, Potreck A, Sauer LD, Kieser M, Bendszus M, et al. Effect of individualized versus standardized blood pressure management during endovascular stroke treatment on clinical outcome: a randomized clinical trial. Stroke. 2023;54(11):2755\u201365. https:\/\/doi.org\/10.1161\/STROKEAHA.123.044062.","journal-title":"Stroke"},{"issue":"2","key":"1246_CR227","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1161\/STROKEAHA.119.026914","volume":"51","author":"M Matusevicius","year":"2020","unstructured":"Matusevicius M, Cooray C, Bottai M, Mazya M, Tsivgoulis G, Nunes AP, et al. Blood pressure after endovascular thrombectomy: modeling for outcomes based on recanalization status. Stroke. 2020;51(2):519\u201325. https:\/\/doi.org\/10.1161\/STROKEAHA.119.026914.","journal-title":"Stroke"},{"key":"1246_CR228","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1161\/HYPERTENSIONAHA.119.14230","volume":"75","author":"K Malhotra","year":"2020","unstructured":"Malhotra K, Goyal N, Katsanos AH, Filippatou A, Mistry EA, Khatri P, et al. Association of blood pressure with outcomes in acute stroke thrombectomy. Hypertension. 2020;75:730\u20139. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.119.14230.","journal-title":"Hypertension"},{"issue":"9","key":"1246_CR229","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1001\/jama.2023.14590","volume":"330","author":"HS Nam","year":"2023","unstructured":"Nam HS, Kim YD, Heo J, Lee H, Jung JW, Choi JK, et al. Intensive vs conventional blood pressure lowering after endovascular thrombectomy in acute ischemic stroke: the OPTIMAL-BP randomized clinical trial. JAMA. 2023;330(9):832\u201342. https:\/\/doi.org\/10.1001\/jama.2023.14590.","journal-title":"JAMA"},{"issue":"1","key":"1246_CR230","doi-asserted-by":"publisher","DOI":"10.1186\/s42466-023-00238-8","volume":"5","author":"M De Georgia","year":"2023","unstructured":"De Georgia M, Bowen T, Duncan KR, Chebl AB. Blood pressure management in ischemic stroke patients undergoing mechanical thrombectomy. Neurol Res Pract. 2023;5(1):12. https:\/\/doi.org\/10.1186\/s42466-023-00238-8. (Mar 30;).","journal-title":"Neurol Res Pract"},{"issue":"5","key":"1246_CR231","doi-asserted-by":"publisher","first-page":"1365","DOI":"10.1097\/00000542-199805000-00029","volume":"88","author":"JE Brian Jr.","year":"1998","unstructured":"Brian JE Jr. Carbon dioxide and the cerebral circulation. Anesthesiology. 1998;88(5):1365\u201386. https:\/\/doi.org\/10.1097\/00000542-199805000-00029.","journal-title":"Anesthesiology"},{"issue":"15","key":"1246_CR232","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12154925","volume":"12","author":"A Scudellari","year":"2023","unstructured":"Scudellari A, Dudek P, Marino L, Badenes R, Bilotta F. Ventilation targets for patients undergoing mechanical thrombectomy for acute ischemic stroke: a systematic review. J Clin Med. 2023;12(15):4925. https:\/\/doi.org\/10.3390\/jcm12154925.","journal-title":"J Clin Med"},{"issue":"1","key":"1246_CR233","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-021-03815-y","volume":"25","author":"M Singer","year":"2021","unstructured":"Singer M, Young PJ, Laffey JG, Asfar P, Taccone FS, Skrifvars MB, et al. Dangers of hyperoxia. Crit Care. 2021;25(1):440. https:\/\/doi.org\/10.1186\/s13054-021-03815-y.","journal-title":"Crit Care"},{"key":"1246_CR234","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1001\/jamaneurol.2016.0992","volume":"73","author":"KN Grelli","year":"2016","unstructured":"Grelli KN, Gindville MC, Walker CH, Jordan LC. Association of blood pressure, blood glucose, and temperature with neurological outcome after childhood stroke. JAMA Neurol. 2016;73:829\u201335. https:\/\/doi.org\/10.1001\/jamaneurol.2016.0992.","journal-title":"JAMA Neurol"},{"issue":"4","key":"1246_CR235","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1001\/jamaneurol.2017.4474","volume":"75","author":"CZ Simonsen","year":"2018","unstructured":"Simonsen CZ, Yoo AJ, S\u00f8rensen LH, Juul N, Johnsen SP, Andersen G, et al. Effect of general anesthesia and conscious sedation during endovascular therapy on infarct growth and clinical outcomes in acute ischemic stroke: a randomized clinical trial. JAMA Neurol. 2018;75(4):470\u20137. https:\/\/doi.org\/10.1001\/jamaneurol.2017.4474.","journal-title":"JAMA Neurol"},{"issue":"6","key":"1246_CR236","doi-asserted-by":"publisher","first-page":"1601","DOI":"10.1161\/STROKEAHA.117.016554","volume":"48","author":"P L\u00f6whagen Hend\u00e9n","year":"2017","unstructured":"L\u00f6whagen Hend\u00e9n P, Rentzos A, Karlsson JE, Rosengren L, Leiram B, Sundeman H, et al. General anesthesia versus conscious sedation for endovascular treatment of acute ischemic stroke: the AnStroke trial (anesthesia during stroke). Stroke. 2017;48(6):1601\u20137. https:\/\/doi.org\/10.1161\/STROKEAHA.117.016554.","journal-title":"Stroke"},{"issue":"19","key":"1246_CR237","doi-asserted-by":"publisher","first-page":"1986","DOI":"10.1001\/jama.2016.16623","volume":"316","author":"S Sch\u00f6nenberger","year":"2016","unstructured":"Sch\u00f6nenberger S, Uhlmann L, Hacke W, Schieber S, Mundiyanapurath S, Purrucker JC, et al. Effect of conscious sedation vs general anesthesia on early neurological improvement among patients with ischemic stroke undergoing endovascular thrombectomy: a randomized clinical trial. JAMA. 2016;316(19):1986\u201396. https:\/\/doi.org\/10.1001\/jama.2016.16623.","journal-title":"JAMA"},{"key":"1246_CR238","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.00170","volume":"11","author":"C Ren","year":"2020","unstructured":"Ren C, Xu G, Liu Y, Liu G, Wang J, Gao J. Effect of conscious sedation vs. general anesthesia on outcomes in patients undergoing mechanical thrombectomy for acute ischemic stroke: a prospective randomized clinical trial. Front Neurol. 2020;11:170. https:\/\/doi.org\/10.3389\/fneur.2020.00170.","journal-title":"Front Neurol"},{"issue":"4","key":"1246_CR239","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1097\/ALN.0000000000004142","volume":"136","author":"A Maurice","year":"2022","unstructured":"Maurice A, Eug\u00e8ne F, Ronzi\u00e8re T, Devys JM, Taylor G, Subileau A, et al. General anesthesia versus sedation, both with hemodynamic control, during intraarterial treatment for stroke: the GASS randomized trial. Anesthesiology. 2022;136(4):567\u201376. https:\/\/doi.org\/10.1097\/ALN.0000000000004142.","journal-title":"Anesthesiology"},{"key":"1246_CR240","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2023.107719","volume":"229","author":"B Vinay","year":"2023","unstructured":"Vinay B, Manohara N, Lobo FA, Lee-St John T, Lamperti M. Inhalational versus intravenous general anesthesia for mechanical thrombectomy for stroke: a single centre retrospective study. Clin Neurol Neurosurg. 2023;229:107719. https:\/\/doi.org\/10.1016\/j.clineuro.2023.107719.","journal-title":"Clin Neurol Neurosurg"},{"issue":"1","key":"1246_CR241","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1097\/ANA.0000000000000639","volume":"33","author":"WK Diprose","year":"2021","unstructured":"Diprose WK, Wang MTM, Campbell D, et al. Intravenous propofol versus volatile anesthetics for stroke endovascular thrombectomy. J Neurosurg Anesth. 2021;33(1):39\u201343. https:\/\/doi.org\/10.1097\/ANA.0000000000000639.","journal-title":"J Neurosurg Anesth"},{"issue":"11","key":"1246_CR242","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1136\/neurintsurg-2015-011998","volume":"8","author":"C Sivasankar","year":"2016","unstructured":"Sivasankar C, Stiefel M, Miano TA, et al. Anesthetic variation and potential impact of anesthetics used during endovascular management of acute ischemic stroke. J Neurointerv Surg. 2016;8(11):1101\u20136. https:\/\/doi.org\/10.1136\/neurintsurg-2015-011998.","journal-title":"J Neurointerv Surg"},{"issue":"11","key":"1246_CR243","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.70116","volume":"14","author":"Z Tao","year":"2024","unstructured":"Tao Z, Li P, Zhao X. Progress on the mechanisms and neuroprotective benefits of dexmedetomidine in brain diseases. Brain Behav. 2024;14(11):e70116. https:\/\/doi.org\/10.1002\/brb3.70116.","journal-title":"Brain Behav"},{"issue":"2","key":"1246_CR244","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1097\/00000542-200302000-00024","volume":"98","author":"LE Nelson","year":"2003","unstructured":"Nelson LE, Lu J, Guo T, Saper CB, Franks NP, Maze M. The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects. Anesthesiology. 2003;98(2):428\u201336. https:\/\/doi.org\/10.1097\/00000542-200302000-00024.","journal-title":"Anesthesiology"},{"issue":"4","key":"1246_CR245","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1016\/j.fmre.2023.02.007","volume":"4","author":"R Li","year":"2023","unstructured":"Li R, Zhang Y, Zhu Q, Wu Y, Song W. The role of anesthesia in peri-operative neurocognitive disorders: molecular mechanisms and preventive strategies. Fundam Res. 2023;4(4):797\u2013805. https:\/\/doi.org\/10.1016\/j.fmre.2023.02.007.","journal-title":"Fundam Res."},{"issue":"11","key":"1246_CR246","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000209953","volume":"103","author":"C Gong","year":"2024","unstructured":"Gong C, Huang J, Qiu Z, Guo M, Chen L, Sang H, et al. Association of conscious sedation with dexmedetomidine and outcome in stroke patients undergoing thrombectomy in the DEVT and RESCUE-BT trials. Neurology. 2024;103(11):e209953. https:\/\/doi.org\/10.1212\/WNL.0000000000209953.","journal-title":"Neurology"},{"issue":"1","key":"1246_CR247","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.aan.2022.06.003","volume":"40","author":"AM Chima","year":"2022","unstructured":"Chima AM, Mahmoud MA, Narayanasamy S. What is the role of dexmedetomidine in modern anesthesia and critical care? Adv Anesth. 2022;40(1):111\u201330. https:\/\/doi.org\/10.1016\/j.aan.2022.06.003.","journal-title":"Adv Anesth"},{"key":"1246_CR248","doi-asserted-by":"publisher","first-page":"1203646","DOI":"10.3389\/fphar.2023.1203646","volume":"14","author":"M Zhou","year":"2023","unstructured":"Zhou M, Luo Q, Xu Y. As an inhibitor of norepinephrine release, dexmedetomidine provides no improvement on stroke-associated pneumonia in mice. Front Pharmacol. 2023;14:1203646. https:\/\/doi.org\/10.3389\/fphar.2023.1203646.","journal-title":"Front Pharmacol"},{"key":"1246_CR249","doi-asserted-by":"publisher","first-page":"842","DOI":"10.1136\/bmj.39169.706574.AD","volume":"334","author":"J Young","year":"2007","unstructured":"Young J, Inouye SK. Delirium in older people. BMJ. 2007;334:842\u20136. https:\/\/doi.org\/10.1136\/bmj.39169.706574.AD.","journal-title":"BMJ"},{"key":"1246_CR250","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1136\/jnnp-2013-305379","volume":"85","author":"SDJ Makin","year":"2014","unstructured":"Makin SDJ, Wardlaw J. Predicting delirium after a stroke. J Neurol Neurosurg Psychiatry. 2014;85:357. https:\/\/doi.org\/10.1136\/jnnp-2013-305379.","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"3","key":"1246_CR251","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1016\/j.jstrokecerebrovasdis.2016.11.120","volume":"26","author":"FJ Alvarez- Perez","year":"2017","unstructured":"Alvarez-Perez FJ, Paiva F. Prevalence and risk factors for delirium in acute stroke patients. A retrospective 5-years clinical series. J Stroke Cerebrovasc Dis. 2017;26(3):567\u201373. https:\/\/doi.org\/10.1016\/j.jstrokecerebrovasdis.2016.11.120.","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"1246_CR252","doi-asserted-by":"publisher","DOI":"10.1161\/SVIN.122.000338","volume":"2","author":"AP Pan","year":"2022","unstructured":"Pan AP, Agarwal K, Taffet GE, Jones SL, Potter T, Bako A, et al. Delirium leads to poor in-hospital and 90-day outcomes among patients with acute ischemic stroke with and without intravenous thrombolysis or intraarterial therapy. Stroke Vasc Interv Neurol. 2022;2:e000338. https:\/\/doi.org\/10.1161\/SVIN.122.000338.","journal-title":"Stroke Vasc Interv Neurol."},{"key":"1246_CR253","doi-asserted-by":"publisher","DOI":"10.1177\/17562864241258788","volume":"17","author":"M Kneihsl","year":"2024","unstructured":"Kneihsl M, Berger N, Sumerauer S, Asenbaum-Nan S, H\u00f6ger FS, Gattringer T, et al. Management of delirium in acute stroke patients: a position paper by the Austrian Stroke Society on prevention, diagnosis, and treatment. Ther Adv Neurol Disord. 2024;17:17562864241258788. https:\/\/doi.org\/10.1177\/17562864241258788.","journal-title":"Ther Adv Neurol Disord"},{"key":"1246_CR254","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2022","volume":"131","author":"TJ Chen","year":"2022","unstructured":"Chen TJ, Traynor V, Wang AY, Shih CY, Tu MC, Chuang CH, et al. Comparative effectiveness of non-pharmacological interventions for preventing delirium in critically ill adults: A systematic review and network meta-analysis. Int J Nurs Stud. 2022;131:104239. https:\/\/doi.org\/10.1016\/j.ijnurstu.2022.","journal-title":"Int J Nurs Stud"},{"issue":"7","key":"1246_CR255","doi-asserted-by":"publisher","first-page":"CD013307","DOI":"10.1002\/14651858.CD013307.pub2","volume":"7","author":"JK Burton","year":"2021","unstructured":"Burton JK, Craig LE, Yong SQ, Siddiqi N, Teale EA, Woodhouse R, et al. Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients. Cochrane Database Syst Rev. 2021;7(7):CD013307. https:\/\/doi.org\/10.1002\/14651858.CD013307.pub2.","journal-title":"Cochrane Database Syst Rev"},{"key":"1246_CR256","doi-asserted-by":"publisher","DOI":"10.1161\/SVIN.122.000634","volume":"3","author":"H Chen","year":"2023","unstructured":"Chen H, Jindal G, Miller TR, Gandhi D, Chaturvedi S. Stroke thrombectomy in the elderly: efficacy, safety, and special considerations. Stroke Vasc IntervNeurol. 2023;3:e000634. https:\/\/doi.org\/10.1161\/SVIN.122.000634.","journal-title":"Stroke Vasc IntervNeurol"},{"issue":"2","key":"1246_CR257","doi-asserted-by":"publisher","first-page":"185","DOI":"10.5853\/jos.2020.00227","volume":"22","author":"FJAM Alverne","year":"2020","unstructured":"Alverne FJAM, Lima FO, Rocha FA, Bandeira DA, Lucena AF, Silva HC, et al. Unfavorable vascular anatomy during endovascular treatment of stroke: challenges and bailout strategies. J Stroke. 2020;22(2):185\u2013202. https:\/\/doi.org\/10.5853\/jos.2020.00227.","journal-title":"J Stroke"},{"issue":"9","key":"1246_CR258","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2023.107248","volume":"32","author":"N Rhiner","year":"2023","unstructured":"Rhiner N, Thut MZ, Thurner P, Madjidyar J, Schubert T, Globas C, et al. Impact of age on mechanical thrombectomy and clinical outcome in patients with acute ischemic stroke. J Stroke Cerebrovasc Dis. 2023;32(9):107248. https:\/\/doi.org\/10.1016\/j.jstrokecerebrovasdis.2023.107248.","journal-title":"J Stroke Cerebrovasc Dis"},{"issue":"5","key":"1246_CR259","doi-asserted-by":"publisher","DOI":"10.1002\/emp2.13048","volume":"4","author":"ES Brandler","year":"2023","unstructured":"Brandler ES, Isenberg DL, Herres J, Zhao H, Kraus CK, Ackerman D, et al. Delay in hospital presentation is the main reason large vessel occlusion stroke patients do not receive intravenous thrombolysis. JACEP Open. 2023;4(5):e13048. https:\/\/doi.org\/10.1002\/emp2.13048.","journal-title":"JACEP Open"},{"key":"1246_CR260","doi-asserted-by":"publisher","first-page":"105677","DOI":"10.1016\/j.neubiorev.2024.105677","volume":"161","author":"DC Carvalho de Abreu","year":"2024","unstructured":"Carvalho de Abreu DC, Pieruccini-Faria F, Son S, Montero-Odasso M, Camicioli R. Is white matter hyperintensity burden associated with cognitive and motor impairment in patients with parkinson\u2019s disease? A systematic review and meta-analysis. Neurosci Biobehav Rev. 2024;161:105677. https:\/\/doi.org\/10.1016\/j.neubiorev.2024.105677.","journal-title":"Neurosci Biobehav Rev"},{"key":"1246_CR261","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2024.102278","volume":"96","author":"AE Morgan","year":"2024","unstructured":"Morgan AE, Mc Auley MT. Vascular dementia: from pathobiology to emerging perspectives. Ageing Res Rev. 2024;96:102278. https:\/\/doi.org\/10.1016\/j.arr.2024.102278.","journal-title":"Ageing Res Rev"},{"issue":"10","key":"1246_CR262","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1136\/neurintsurg-2019-015652","volume":"12","author":"I Mark","year":"2020","unstructured":"Mark I, Seyedsaadat SM, Benson JC, Kallmes DF, Rabinstein AA, Brinjikji W. Leukoaraiosis and collateral blood flow in stroke patients with anterior circulation large vessel occlusion. J Neurointerv Surg. 2020;12(10):942\u20135. https:\/\/doi.org\/10.1136\/neurintsurg-2019-015652.","journal-title":"J Neurointerv Surg."},{"issue":"4","key":"1246_CR263","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1136\/neurintsurg-2020-015957","volume":"13","author":"JC Benson","year":"2021","unstructured":"Benson JC, Seyedsaadat SM, Mark I, Nasr DM, Rabinstein AA, Kallmes DF, et al. Leukoaraiosis and acute ischemic stroke: 90-day clinical outcome following endovascular recanalization, with proposed \u201cL-ASPECTS.\u201d J Neurointerv Surg. 2021;13(4):384\u20139. https:\/\/doi.org\/10.1136\/neurintsurg-2020-015957.","journal-title":"J Neurointerv Surg."}],"container-title":["Drugs & Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40266-025-01246-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40266-025-01246-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40266-025-01246-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T01:06:34Z","timestamp":1761699994000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40266-025-01246-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,24]]},"references-count":263,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["1246"],"URL":"https:\/\/doi.org\/10.1007\/s40266-025-01246-w","relation":{},"ISSN":["1170-229X","1179-1969"],"issn-type":[{"value":"1170-229X","type":"print"},{"value":"1179-1969","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,24]]},"assertion":[{"value":"22 May 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 August 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 September 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Dr. Vinay Byrappa, Dr. Nitin Manohara, and Dr. Amit Jain declare that they do not have any conflict of interest that might be relevant to the content of this manuscript","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Availability of Data and Material"}},{"value":"V.B. conceptualized the idea, did the literature search, original draft preparation. N.M. helped research the methodology and drafted the manuscript. A.J. provided guidance, critically revised the article and proofread the manuscript.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Author Contributions"}},{"value":"Not applicable.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code Availability"}}]}}