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Written informed consents were obtained from all participants.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval and Consent to Participate"}},{"value":"This study was financially supported by Zhejiang Provincial Program for the Cultivation of New Health Talents (to Yiwen Zhang), Zhejiang Provincial TCM Science and Technology Plan Project (2021ZZ001 and 2022ZB017), and the Medical Science and Technology Project of Zhejiang Provincial (2021KY040 and 2022KY069).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"Rui Hao, Yiming Shao, Sisi Lin, Yi Wu, Li Bian, and Yiwen Zhang declare no conflicts of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, the license permits any non-commercial use, sharing, adaptation, distribution, and reproduction in any format or medium.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code Availability"}},{"value":"This study was designed by YZ. 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