{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T08:04:47Z","timestamp":1784189087793,"version":"3.55.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"name":"Novo Nordisk A\/S","award":["KI 4-3128\/2022"],"award-info":[{"award-number":["KI 4-3128\/2022"]}]},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"crossref","award":["2024-03599"],"award-info":[{"award-number":["2024-03599"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"crossref","award":["2023-00356"],"award-info":[{"award-number":["2023-00356"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"crossref","award":["2022-01018"],"award-info":[{"award-number":["2022-01018"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"crossref","award":["2019-02397"],"award-info":[{"award-number":["2019-02397"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"crossref"}]},{"name":"ALF-agreement","award":["ALFGBG-1005471"],"award-info":[{"award-number":["ALFGBG-1005471"]}]},{"name":"ALF-agreement","award":["ALFGBG-965923"],"award-info":[{"award-number":["ALFGBG-965923"]}]},{"name":"ALF-agreement","award":["ALFGBG-81392"],"award-info":[{"award-number":["ALFGBG-81392"]}]},{"name":"ALF-agreement","award":["AF-939825"],"award-info":[{"award-number":["AF-939825"]}]},{"name":"the Paulsson foundation"},{"name":"the European Union\u2019s Horizon Europe research and innovation programme","award":["101053962"],"award-info":[{"award-number":["101053962"]}]},{"name":"Swedish State Support for Clinical Research","award":["ALFGBG-71320"],"award-info":[{"award-number":["ALFGBG-71320"]}]},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"crossref","award":["2019-02075"],"award-info":[{"award-number":["2019-02075"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"crossref","award":["2019-02075_15"],"award-info":[{"award-number":["2019-02075_15"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100008587","name":"Stiftelsen Psykiatriska Forskningsfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003792","name":"Swedish Brain Foundation","doi-asserted-by":"crossref","award":["FO2024-0097"],"award-info":[{"award-number":["FO2024-0097"]}],"id":[{"id":"10.13039\/501100003792","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100008599","name":"Alzheimerfonden","doi-asserted-by":"publisher","award":["AF-842471"],"award-info":[{"award-number":["AF-842471"]}],"id":[{"id":"10.13039\/501100008599","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008599","name":"Alzheimerfonden","doi-asserted-by":"publisher","award":["AF-737641"],"award-info":[{"award-number":["AF-737641"]}],"id":[{"id":"10.13039\/501100008599","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008599","name":"Alzheimerfonden","doi-asserted-by":"publisher","award":["AF-92995"],"award-info":[{"award-number":["AF-92995"]}],"id":[{"id":"10.13039\/501100008599","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008599","name":"Alzheimerfonden","doi-asserted-by":"publisher","award":["AF-939825"],"award-info":[{"award-number":["AF-939825"]}],"id":[{"id":"10.13039\/501100008599","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001858","name":"VINNOVA","doi-asserted-by":"publisher","award":["2021-02680"],"award-info":[{"award-number":["2021-02680"]}],"id":[{"id":"10.13039\/501100001858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002565","name":"Alzheimer's Drug Discovery Foundation","doi-asserted-by":"publisher","award":["201809-2016862"],"award-info":[{"award-number":["201809-2016862"]}],"id":[{"id":"10.13039\/100002565","id-type":"DOI","asserted-by":"publisher"}]},{"name":"AD Strategic Fund and the Alzheimer's Association","award":["ADSF-21-831376-C"],"award-info":[{"award-number":["ADSF-21-831376-C"]}]},{"name":"AD Strategic Fund and the Alzheimer's Association","award":["ADSF-21-831381-C"],"award-info":[{"award-number":["ADSF-21-831381-C"]}]},{"name":"AD Strategic Fund and the Alzheimer's Association","award":["ADSF-21-831377-C"],"award-info":[{"award-number":["ADSF-21-831377-C"]}]},{"name":"AD Strategic Fund and the Alzheimer's Association","award":["ADSF-24-1284328-C"],"award-info":[{"award-number":["ADSF-24-1284328-C"]}]},{"name":"the European Partnership on Metrology, co-financed from the European Union\u2019s Horizon Europe Research and Innovation Programme and by the Participating States","award":["22HLT07"],"award-info":[{"award-number":["22HLT07"]}]},{"name":"Bluefield Project"},{"DOI":"10.13039\/100007625","name":"Cure Alzheimer\u2019s Fund","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100007625","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100021720","name":"Olav Thon Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100021720","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100007436","name":"Erling-Persson Family Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100007436","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Familjen R\u00f6nstr\u00f6ms Stiftelse"},{"name":"Familjen Beiglers Stiftelse"},{"DOI":"10.13039\/100010815","name":"Stiftelsen f\u00f6r Gamla Tj\u00e4narinnor","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010815","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003792","name":"Hj\u00e4rnfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003792","id-type":"DOI","asserted-by":"publisher"}]},{"name":"the European Union\u2019s Horizon 2020 research and innovation programme","award":["860197"],"award-info":[{"award-number":["860197"]}]},{"name":"European Union Joint Programme\u2014Neurodegenerative Disease Research","award":["JPND2021-00694"],"award-info":[{"award-number":["JPND2021-00694"]}]},{"name":"the National Institute for Health and Care Research University College London Hospitals Biomedical Research Centre, the UK Dementia Research Institute at UCL","award":["UKDRI-1003"],"award-info":[{"award-number":["UKDRI-1003"]}]},{"name":"Innovative Health Initiative Joint Undertaking","award":["101112145"],"award-info":[{"award-number":["101112145"]}]},{"name":"the Swedish Research Council for Health, Working Life and Welfare"},{"name":"Open access funding provided by Karolinska Institute"},{"DOI":"10.13039\/501100004047","name":"Karolinska Institute","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["PharmacoEconomics"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1007\/s40273-026-01612-5","type":"journal-article","created":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T10:10:24Z","timestamp":1775038224000},"page":"937-948","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Utilization and Lifetime Costs of Formal Care for Alzheimer\u2019s Disease Dementia in Sweden"],"prefix":"10.1007","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8101-0563","authenticated-orcid":false,"given":"Xin","family":"Xia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Eriksdotter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Clark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niels Juul","family":"Brogaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Gundgaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pepa","family":"Polavieja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils","family":"Skajaa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Zetterberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silke","family":"Kern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias Borgh","family":"Skillb\u00e4ck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linus","family":"J\u00f6nsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,1]]},"reference":[{"key":"1612_CR1","doi-asserted-by":"crossref","unstructured":"2024 Alzheimer\u2019s disease facts and figures. Alzheimers Dement. 2024;20(5):3708\u2013821.","DOI":"10.1002\/alz.13809"},{"issue":"11","key":"1612_CR2","doi-asserted-by":"publisher","first-page":"1988","DOI":"10.1016\/j.ajpath.2024.10.014","volume":"195","author":"RJ Castellani","year":"2024","unstructured":"Castellani RJ, Jamshidi P, Plascencia-Villa G, Perry G. The amyloid cascade hypothesis: a conclusion in search of support. Am J Pathol. 2024;195(11):1988\u201397.","journal-title":"Am J Pathol"},{"issue":"7","key":"1612_CR3","doi-asserted-by":"publisher","first-page":"2865","DOI":"10.1002\/alz.12901","volume":"19","author":"A Wimo","year":"2023","unstructured":"Wimo A, Seeher K, Cataldi R, Cyhlarova E, Dielemann JL, Frisell O, et al. The worldwide costs of dementia in 2019. Alzheimers Dement. 2023;19(7):2865\u201373.","journal-title":"Alzheimers Dement"},{"key":"1612_CR4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.vhri.2023.09.008","volume":"40","author":"LX Tay","year":"2024","unstructured":"Tay LX, Ong SC, Tay LJ, Ng T, Parumasivam T. Economic burden of Alzheimer\u2019s disease: a systematic review. Value Health Reg Issues. 2024;40:1\u201312.","journal-title":"Value Health Reg Issues"},{"issue":"2","key":"1612_CR5","doi-asserted-by":"publisher","first-page":"e105","DOI":"10.1016\/S2468-2667(21)00249-8","volume":"7","author":"Collaborators GBDDF","year":"2022","unstructured":"Collaborators GBDDF. Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019. Lancet Public Health. 2022;7(2):e105\u201325.","journal-title":"Lancet Public Health"},{"issue":"1","key":"1612_CR6","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1007\/s40273-022-01212-z","volume":"41","author":"L Jonsson","year":"2023","unstructured":"Jonsson L, Tate A, Frisell O, Wimo A. The costs of dementia in Europe: an updated review and meta-analysis. Pharmacoeconomics. 2023;41(1):59\u201375.","journal-title":"Pharmacoeconomics"},{"issue":"1","key":"1612_CR7","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1056\/NEJMoa2212948","volume":"388","author":"CH van Dyck","year":"2023","unstructured":"van Dyck CH, Swanson CJ, Aisen P, Bateman RJ, Chen C, Gee M, et al. Lecanemab in early Alzheimer\u2019s disease. N Engl J Med. 2023;388(1):9\u201321.","journal-title":"N Engl J Med"},{"issue":"6","key":"1612_CR8","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1001\/jama.2023.13239","volume":"330","author":"JR Sims","year":"2023","unstructured":"Sims JR, Zimmer JA, Evans CD, Lu M, Ardayfio P, Sparks J, et al. Donanemab in early symptomatic Alzheimer disease: the TRAILBLAZER-ALZ 2 randomized clinical trial. JAMA. 2023;330(6):512\u201327.","journal-title":"JAMA"},{"issue":"1","key":"1612_CR9","doi-asserted-by":"publisher","first-page":"29","DOI":"10.14283\/jpad.2019.41","volume":"7","author":"A Rosenberg","year":"2020","unstructured":"Rosenberg A, Mangialasche F, Ngandu T, Solomon A, Kivipelto M. Multidomain interventions to prevent cognitive impairment, Alzheimer\u2019s disease, and dementia: from FINGER to World-Wide FINGERS. J Prev Alzheimers Dis. 2020;7(1):29\u201336.","journal-title":"J Prev Alzheimers Dis"},{"issue":"3","key":"1612_CR10","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1007\/s10198-024-01707-w","volume":"26","author":"J Zilling","year":"2025","unstructured":"Zilling J, Gerdtham UG, Jarl J, Saha S, Persson S. The formal care costs of dementia: a longitudinal study using Swedish register data. Eur J Health Econ. 2025;26(3):353\u201361.","journal-title":"Eur J Health Econ"},{"issue":"2","key":"1612_CR11","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1007\/s40273-024-01443-2","volume":"43","author":"S Aye","year":"2025","unstructured":"Aye S, Frisell O, Zetterberg H, Skillback TB, Kern S, Eriksdotter M, et al. Costs of care in relation to Alzheimer\u2019s disease severity in Sweden: a National Registry-based cohort study. Pharmacoeconomics. 2025;43(2):153\u201369.","journal-title":"Pharmacoeconomics"},{"issue":"2","key":"1612_CR12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0116538","volume":"10","author":"D Religa","year":"2015","unstructured":"Religa D, Fereshtehnejad SM, Cermakova P, Edlund AK, Garcia-Ptacek S, Granqvist N, et al. SveDem, the Swedish Dementia Registry\u2014a tool for improving the quality of diagnostics, treatment and care of dementia patients in clinical practice. PLoS ONE. 2015;10(2):e0116538.","journal-title":"PLoS ONE"},{"key":"1612_CR13","unstructured":"Socialstyrelsen. Nationella riktlinjer: demenssjukdom. 2017. https:\/\/www.socialstyrelsen.se\/publikationer\/nationella-riktlinjer-for-vard-och-omsorg-vid-demenssjukdom-2017-12-2\/. Accessed\u00a09 Jan 2026."},{"issue":"1\u20132","key":"1612_CR14","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1159\/000366194","volume":"39","author":"F Falahati","year":"2015","unstructured":"Falahati F, Fereshtehnejad SM, Religa D, Wahlund LO, Westman E, Eriksdotter M. The use of MRI, CT and lumbar puncture in dementia diagnostics: data from the SveDem Registry. Dement Geriatr Cogn Disord. 2015;39(1\u20132):81\u201391.","journal-title":"Dement Geriatr Cogn Disord"},{"key":"1612_CR15","unstructured":"Socialstyrelsen. National Patient Register. 2024. https:\/\/www.socialstyrelsen.se\/en\/statistics-and-data\/registers\/national-patient-register\/. Accessed\u00a09 Jan 2026."},{"key":"1612_CR16","unstructured":"Socialstyrelsen. National Prescribed Drug Register. 2024. https:\/\/www.socialstyrelsen.se\/en\/statistics-and-data\/registers\/national-prescribed-drug-register\/. Accessed\u00a09 Jan 2026."},{"key":"1612_CR17","unstructured":"Socialstyrelsen. National Register of Care and Social Services for the Elderly and Persons with Impairments. 2024. https:\/\/www.socialstyrelsen.se\/en\/statistics-and-data\/registers\/national-register-of-care-and-social-services-for-the-elderly-and-persons-with-impairments\/. Accessed\u00a09 Jan 2026."},{"key":"1612_CR18","unstructured":"SKR. Kostnad per patient (KPP). 2025. https:\/\/skr.se\/halsaochsjukvard\/ekonomiochavgiftersjukvard\/kostnadperpatientkpp.7873.html. Accessed\u00a09 Jan 2026."},{"issue":"3","key":"1612_CR19","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1177\/1536867X1501500305","volume":"15","author":"S Chen","year":"2015","unstructured":"Chen S, Rolfes J, Zhao H. Estimation of mean health care costs and incremental cost-effectiveness ratios with possibly censored data. Stata J. 2015;15(3):698\u2013711.","journal-title":"Stata J"},{"key":"1612_CR20","doi-asserted-by":"publisher","DOI":"10.1136\/bmj-2024-080636","volume":"388","author":"CC Bruck","year":"2025","unstructured":"Bruck CC, Mooldijk SS, Kuiper LM, Sambou ML, Licher S, Mattace-Raso F, et al. Time to nursing home admission and death in people with dementia: systematic review and meta-analysis. BMJ. 2025;388:e080636.","journal-title":"BMJ"},{"issue":"3","key":"1612_CR21","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/j.jalz.2010.09.001","volume":"7","author":"A Gustavsson","year":"2011","unstructured":"Gustavsson A, Brinck P, Bergvall N, Kolasa K, Wimo A, Winblad B, et al. Predictors of costs of care in Alzheimer\u2019s disease: a multinational sample of 1222 patients. Alzheimers Dement. 2011;7(3):318\u201327.","journal-title":"Alzheimers Dement"},{"issue":"3","key":"1612_CR22","doi-asserted-by":"publisher","first-page":"797","DOI":"10.3233\/JAD-160449","volume":"57","author":"C Reed","year":"2017","unstructured":"Reed C, Happich M, Argimon JM, Haro JM, Wimo A, Bruno G, et al. What drives country differences in cost of Alzheimer\u2019s disease? An explanation from resource use in the GERAS study. J Alzheimers Dis. 2017;57(3):797\u2013812.","journal-title":"J Alzheimers Dis"},{"issue":"1","key":"1612_CR23","doi-asserted-by":"publisher","first-page":"55","DOI":"10.14283\/jpad.2017.31","volume":"5","author":"G Bruno","year":"2018","unstructured":"Bruno G, Mancini M, Bruti G, Dell\u2019Agnello G, Reed C. Costs and resource use associated with Alzheimer\u2019s disease in Italy: results from an observational study. J Prev Alzheimers Dis. 2018;5(1):55\u201364.","journal-title":"J Prev Alzheimers Dis."},{"issue":"3","key":"1612_CR24","doi-asserted-by":"publisher","first-page":"899","DOI":"10.3233\/JAD-180306","volume":"64","author":"CW Ritchie","year":"2018","unstructured":"Ritchie CW, Khandker RK, Pike J, Black CM, Jones E, Ambegaonkar BM. Real-world, multinational, retrospective observational survey of the ADAS-Cog and associations with healthcare resource utilization in patients with Alzheimer\u2019s disease. J Alzheimers Dis. 2018;64(3):899\u2013910.","journal-title":"J Alzheimers Dis"},{"issue":"4","key":"1612_CR25","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.3233\/JAD-190760","volume":"75","author":"RK Khandker","year":"2020","unstructured":"Khandker RK, Ritchie CW, Black CM, Wood R, Jones E, Hu X, et al. Multi-national, cross-sectional survey of healthcare resource utilization in patients with all stages of cognitive impairment, analyzed by disease severity, country, and geographical region. J Alzheimers Dis. 2020;75(4):1141\u201352.","journal-title":"J Alzheimers Dis"},{"issue":"1","key":"1612_CR26","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/s13195-022-00969-x","volume":"14","author":"V Dauphinot","year":"2022","unstructured":"Dauphinot V, Potashman M, Levitchi-Benea M, Su R, Rubino I, Krolak-Salmon P. Economic and caregiver impact of Alzheimer\u2019s disease across the disease spectrum: a cohort study. Alzheimers Res Ther. 2022;14(1):34.","journal-title":"Alzheimers Res Ther."},{"issue":"1","key":"1612_CR27","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1007\/s41669-023-00451-w","volume":"8","author":"L Gomez Maldonado","year":"2024","unstructured":"Gomez Maldonado L, de Mora-Figueroa R, Lopez-Angarita A, Maravilla-Herrera P, Merino M. Cost of patients with Alzheimer\u2019s disease in Spain according to disease severity. Pharmacoecon Open. 2024;8(1):103\u201314.","journal-title":"Pharmacoecon Open."},{"issue":"1","key":"1612_CR28","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1080\/13696998.2024.2442240","volume":"28","author":"E Fazio-Eynullayeva","year":"2025","unstructured":"Fazio-Eynullayeva E, Cunnington M, Mystkowski P, Lv L, Aly A, Yee CW, et al. Real-world healthcare resource utilization of Alzheimer\u2019s disease in the early and advanced stages: a retrospective cohort study. J Med Econ. 2025;28(1):81\u20138.","journal-title":"J Med Econ"},{"issue":"4","key":"1612_CR29","doi-asserted-by":"publisher","first-page":"983","DOI":"10.14283\/jpad.2024.68","volume":"11","author":"FH Frech","year":"2024","unstructured":"Frech FH, Li G, Juday T, Ding Y, Mattke S, Khachaturian A, et al. Economic impact of progression from mild cognitive impairment to Alzheimer disease in the United States. J Prev Alzheimers Dis. 2024;11(4):983\u201391.","journal-title":"J Prev Alzheimers Dis."},{"issue":"9","key":"1612_CR30","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1097\/MLR.0000000000001380","volume":"58","author":"PA Fishman","year":"2020","unstructured":"Fishman PA, White L, Ingraham B, Park S, Larson EB, Crane P, et al. Health care costs of Alzheimer\u2019s and related dementias within a medicare managed care provider. Med Care. 2020;58(9):833\u201341.","journal-title":"Med Care"},{"issue":"3","key":"1612_CR31","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1007\/s10198-018-1001-3","volume":"20","author":"M Belger","year":"2019","unstructured":"Belger M, Haro JM, Reed C, Happich M, Argimon JM, Bruno G, et al. Determinants of time to institutionalisation and related healthcare and societal costs in a community-based cohort of patients with Alzheimer\u2019s disease dementia. Eur J Health Econ. 2019;20(3):343\u201355.","journal-title":"Eur J Health Econ"},{"issue":"1","key":"1612_CR32","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1186\/s12889-022-13099-8","volume":"22","author":"B Meinow","year":"2022","unstructured":"Meinow B, Li P, Jasilionis D, Oksuzyan A, Sundberg L, Kelfve S, et al. Trends over two decades in life expectancy with complex health problems among older Swedes: implications for the provision of integrated health care and social care. BMC Public Health. 2022;22(1):759.","journal-title":"BMC Public Health"}],"container-title":["PharmacoEconomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40273-026-01612-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40273-026-01612-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40273-026-01612-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T07:20:55Z","timestamp":1784186455000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40273-026-01612-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,1]]},"references-count":32,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["1612"],"URL":"https:\/\/doi.org\/10.1007\/s40273-026-01612-5","relation":{},"ISSN":["1170-7690","1179-2027"],"issn-type":[{"value":"1170-7690","type":"print"},{"value":"1179-2027","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,1]]},"assertion":[{"value":"14 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Open access funding provided by Karolinska Institute. The study is funded by Novo Nordisk A\/S under a research collaboration agreement (Dnr KI 4-3128\/2022). M.E. was supported by the Swedish Research Council (2024-03599), the Swedish Brain Foundation (FO2024-0339), the regional agreement on medical training and clinical research between the Stockholm County council and the Karolinska Institutet (ALF), PREDEM (Vinnova grant 2021-02680), the Center for Innovative medicine, and the Paulsson foundation. H.Z. is a Wallenberg Scholar and a Distinguished Professor at the Swedish Research Council supported by grants from the Swedish Research Council (#2023-00356, #2022-01018 and #2019-02397), the European Union\u2019s Horizon Europe research and innovation programme under grant agreement No 101053962, and Swedish State Support for Clinical Research (#ALFGBG-71320), the Alzheimer Drug Discovery Foundation (ADDF), USA (201809-2016862), the AD Strategic Fund and the Alzheimer\u2019s Association (ADSF-21-831376-C, ADSF-21-831381-C, ADSF-21-831377-C, and ADSF-24-1284328-C), the European Partnership on Metrology, co-financed from the European Union\u2019s Horizon Europe Research and Innovation Programme and by the Participating States (NEuroBioStand, 22HLT07), the Bluefield Project, Cure Alzheimer\u2019s Fund, the Olav Thon Foundation, the Erling-Persson Family Foundation, Familjen R\u00f6nstr\u00f6ms Stiftelse, Familjen Beiglers Stiftelse, Stiftelsen f\u00f6r Gamla Tj\u00e4narinnor, Hj\u00e4rnfonden, Sweden (FO2022-0270), the European Union\u2019s Horizon 2020 research and innovation programme under the Marie Sk\u0142odowska-Curie grant agreement 860197 (MIRIADE), the European Union Joint Programme\u2014Neurodegenerative Disease Research (JPND2021-00694), the National Institute for Health and Care Research University College London Hospitals Biomedical Research Centre, the UK Dementia Research Institute at UCL (UKDRI-1003), and an anonymous donor. S.K. was financed by grants from the Swedish state under the agreement between the Swedish government and the county councils, the ALF-agreement (ALFGBG-1005471, ALFGBG-965923, ALFGBG-81392, ALFGBG-771071), the Alzheimerfonden (AF-842471, AF-737641, AF-929959, AF-939825), the Swedish Research Council (2019-02075, 2019-02075_15), Stiftelsen Psykiatriska Forskningsfonden, and the Swedish Brain Foundation (FO2024-0097). LJ is funded by the Innovative Health Initiative Joint Undertaking under grant agreement 101112145, PREDEM (Vinnova grant 2021-02680), the Swedish Research Council for Health, Working Life and Welfare, and Novo Nordisk.","order":1,"name":"Ethics","label":"Funding","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"ME has served as speaker and\/or consultant for BioArctic AB, Roche, Eli Lilly, Biogen\/Eisai and Novo Nordisk and given lectures in symposia sponsored by Roche. HZ has served at scientific advisory boards and\/or as a consultant for Abbvie, Acumen, Alector, Alzinova, ALZpath, Amylyx, Annexon, Apellis, Artery Therapeutics, AZTherapies, Cognito Therapeutics, CogRx, Denali, Eisai, Enigma, LabCorp, Merck Sharp & Dohme, Merry Life, Nervgen, Novo Nordisk, Optoceutics, Passage Bio, Pinteon Therapeutics, Prothena, Quanterix, Red Abbey Labs, reMYND, Roche, Samumed, ScandiBio Therapeutics AB, Siemens Healthineers, Triplet Therapeutics, and Wave, has given lectures sponsored by Alzecure, BioArctic, Biogen, Cellectricon, Fujirebio, LabCorp, Lilly, Novo Nordisk, Oy Medix Biochemica AB, Roche, and WebMD, is a co-founder of Brain Biomarker Solutions in Gothenburg AB (BBS), which is a part of the GU Ventures Incubator Program, and is a shareholder of MicThera (outside submitted work). SK has served at scientific advisory boards, speaker and\/or as consultant for Roche, Eli Lilly, Geras Solutions, Optoceutics, Biogen, Eisai, Merry Life, Triolab, Novo Nordisk and BioArctic. LJ has received consulting fees from H. Lundbeck A\/S, Novo Nordisk A\/S and TEVA Inc, and license fees for the Resource Utilization in Dementia (RUD) instrument and has given lectures sponsored by Eli Lilly and Novo Nordisk. LJ is an Editorial Board Member of PharmacoEconomics. He was not involved in the selection of peer reviewers for the manuscript nor any of the subsequent editorial decisions. Others report no conflicts of interest pertinent to this work.","order":2,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the Swedish Ethical Review Authority (DNR: 2024-07272-02).","order":3,"name":"Ethics","label":"Ethical statements","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"In accordance with Swedish regulations, we are unable to share the data used in this study. Researchers can access the Swedish registers after receiving ethical approvals from ethical review authorities and approvals from the register holders.","order":4,"name":"Ethics","label":"Data sharing","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"LJ conceptualized the study. XX designed the study, analyzed data, and drafted and revised the manuscript. LJ received funding for this study. LJ, ME, HZ, SK, and TS contributed to data acquisition. All co-authors (ME, AC, NB, JG, PP, NS, HZ, SK, TS, and LJ) have reviewed the manuscript, provided critical feedback, and approved the submission of the manuscript for publication.","order":5,"name":"Ethics","label":"Author contributions","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"We cannot share raw data used in the current study following Swedish laws. However, SveDemdata are accessible after ethical approvals and approvals from the SveDem steering group.","order":6,"name":"Ethics","label":"Data availability","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Analytical codes for this study will be shared upon request.","order":7,"name":"Ethics","label":"Code availability","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Participants were informed of the registration of their data in SveDem and had the right to decline the registration. Written informed consent is not required for register-based research in Sweden.","order":8,"name":"Ethics","label":"Consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":9,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}}]}}