{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T18:53:46Z","timestamp":1793559226850,"version":"4.5.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T00:00:00Z","timestamp":1675814400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T00:00:00Z","timestamp":1675814400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005690","name":"Universit\u00e4t des Saarlandes","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005690","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sports Med"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Playing football is associated with a high risk of injury. Injury prevention is a priority as injuries not only negatively impact health but also potentially performance. Various multi-component exercise-based injury prevention programs for football players have been examined in studies.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Objective<\/jats:title>\n                <jats:p>We aimed to investigate the efficacy of multi-component exercise-based injury prevention programs among footballers of all age groups in comparison to a control group.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We conducted a systematic review and meta-analysis of randomized and cluster-randomized controlled trials. CINAHL, Cochrane, PubMed, Scopus, and Web of Science databases were searched from inception to June 2022. The following inclusion criteria were used for studies to determine their eligibility: they (1) include football (soccer) players; (2) investigate the preventive effect of multi-component exercise-based injury prevention programs in football; (3) contain original data from a randomized or cluster-randomized trial; and (4) investigate football injuries as the outcome. The risk of bias and quality of evidence were assessed using the Cochrane Risk of Bias Tool and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE), respectively. The outcome measures were the risk ratio (RR) between the intervention and the control group for the overall number of injuries and body region-specific, contact, and non-contact injuries sustained during the study period in training and match play.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Fifteen randomized and cluster-randomized controlled trials with 22,177 players, 5080 injuries, and 1,587,327 exposure hours fulfilled the inclusion criteria and reported the required outcome measures. The point estimate (RR) for the overall number of injuries was 0.71 (95% confidence interval [CI] 0.59\u20130.85; 95% prediction interval [PI] 0.38\u20131.32) with very low-quality evidence. The point estimate (RR) for lower limb injuries was 0.82 (95% CI 0.71\u20130.94; 95% PI 0.58\u20131.15) with moderate-quality evidence; for hip\/groin injuries, the RR was 0.56 (95% CI 0.30\u20131.05; 95% PI 0.00\u2013102.92) with low-quality evidence; for knee injuries, the RR was 0.69 (95% CI 0.52\u20130.90; 95% PI 0.31\u20131.50) with low-quality evidence; for ankle injuries, the RR was 0.73 (95% CI 0.55\u20130.96; 95% PI 0.36\u20131.46) with moderate-quality evidence; and for hamstring injuries, the RR was 0.83 (95% CI 0.50\u20131.37) with low-quality evidence. The point estimate (RR) for contact injuries was 0.70 (95% CI 0.56\u20130.88; 95% PI 0.40\u20131.24) with moderate-quality evidence, while for non-contact injuries, the RR was 0.78 (95% CI 0.55\u20131.10; 95% PI 0.25\u20132.47) with low-quality evidence.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>This systematic review and meta-analysis indicated that the treatment effect associated with the use of multi-component exercise-based injury prevention programs in football is uncertain and inconclusive. In addition, the majority of the results are based on low-quality evidence. Therefore, future high-quality trials are needed to provide\u00a0more\u00a0reliable evidence.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Clinical Trial Registration<\/jats:title>\n                <jats:p>PROSPERO CRD42020221772.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s40279-022-01797-7","type":"journal-article","created":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T11:33:20Z","timestamp":1675856000000},"page":"837-848","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Efficacy of Multi-Component Exercise-Based Injury Prevention Programs on Injury Risk Among Footballers of All Age Groups: A Systematic Review and Meta-analysis"],"prefix":"10.1007","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3468-8822","authenticated-orcid":false,"given":"Rilind","family":"Ob\u00ebrtinca","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilir","family":"Hoxha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rina","family":"Meha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arber","family":"Lama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Altina","family":"Bimbashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorentina","family":"Kuqi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bujar","family":"Shabani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen aus","family":"der F\u00fcnten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,2,8]]},"reference":[{"issue":"6","key":"1797_CR1","doi-asserted-by":"publisher","first-page":"786","DOI":"10.4085\/1062-6050-49.3.51","volume":"49","author":"K Aus der F\u00fcnten","year":"2014","unstructured":"Aus der F\u00fcnten K, Faude O, Lensch J, Meyer T. Injury characteristics in the German professional male soccer leagues after a shortened winter break. J Athl Train. 2014;49(6):786\u201393. https:\/\/doi.org\/10.4085\/1062-6050-49.3.51.","journal-title":"J Athl Train"},{"issue":"2","key":"1797_CR2","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/j.jsams.2014.02.004","volume":"18","author":"AM van Beijsterveldt","year":"2015","unstructured":"van Beijsterveldt AM, Stubbe JH, Schmikli SL, van de Port IG, Backx FJ. Differences in injury risk and characteristics between Dutch amateur and professional soccer players. J Sci Med Sport. 2015;18(2):145\u20139. https:\/\/doi.org\/10.1016\/j.jsams.2014.02.004.","journal-title":"J Sci Med Sport"},{"issue":"2","key":"1797_CR3","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1007\/s00402-021-03861-9","volume":"142","author":"D Szymski","year":"2022","unstructured":"Szymski D, Krutsch V, Achenbach L, Gerling S, Pfeifer C, Alt V, et al. Epidemiological analysis of injury occurrence and current prevention strategies on international amateur football level during the UEFA Regions Cup 2019. Arch Orthop Trauma Surg. 2022;142(2):271\u201380. https:\/\/doi.org\/10.1007\/s00402-021-03861-9.","journal-title":"Arch Orthop Trauma Surg"},{"issue":"9","key":"1797_CR4","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1080\/02640414.2014.975736","volume":"33","author":"D Hammes","year":"2015","unstructured":"Hammes D, Aus der F\u00fcnten K, Kaiser S, Frisen E, Bizzini M, Meyer T. Injury prevention in male veteran football players: a randomised controlled trial using \u201cFIFA 11+\u201d. J Sports Sci. 2015;33(9):873\u201381. https:\/\/doi.org\/10.1080\/02640414.2014.975736.","journal-title":"J Sports Sci."},{"issue":"9","key":"1797_CR5","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1007\/s40279-013-0061-x","volume":"43","author":"O Faude","year":"2013","unstructured":"Faude O, R\u00f6\u00dfler R, Junge A. Football injuries in children and adolescent players: are there clues for prevention? Sports Med. 2013;43(9):819\u201337. https:\/\/doi.org\/10.1007\/s40279-013-0061-x.","journal-title":"Sports Med"},{"issue":"7","key":"1797_CR6","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1136\/bjsm.2009.060582","volume":"45","author":"J Ekstrand","year":"2011","unstructured":"Ekstrand J, H\u00e4gglund M, Wald\u00e9n M. Injury incidence and injury patterns in professional football: the UEFA injury study. Br J Sports Med. 2011;45(7):553\u20138. https:\/\/doi.org\/10.1136\/bjsm.2009.060582.","journal-title":"Br J Sports Med"},{"issue":"9","key":"1797_CR7","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1136\/bjsports-2020-102859","volume":"55","author":"O Materne","year":"2021","unstructured":"Materne O, Chamari K, Farooq A, Weir A, H\u00f6lmich P, Bahr R, et al. Injury incidence and burden in a youth elite football academy: a four-season prospective study of 551 players aged from under 9 to under 19 years. Br J Sports Med. 2021;55(9):493\u2013500. https:\/\/doi.org\/10.1136\/bjsports-2020-102859.","journal-title":"Br J Sports Med"},{"issue":"8","key":"1797_CR8","doi-asserted-by":"publisher","first-page":"1476","DOI":"10.1177\/0363546508318188","volume":"36","author":"J Gilchrist","year":"2008","unstructured":"Gilchrist J, Mandelbaum BR, Melancon H, Ryan GW, Silvers HJ, Griffin LY, et al. A randomized controlled trial to prevent noncontact anterior cruciate ligament injury in female collegiate soccer players. Am J Sports Med. 2008;36(8):1476\u201383. https:\/\/doi.org\/10.1177\/0363546508318188","journal-title":"Am J Sports Med"},{"key":"1797_CR9","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e3042","volume":"344","author":"M Wald\u00e9n","year":"2012","unstructured":"Wald\u00e9n M, Atroshi I, Magnusson H, Wagner P, H\u00e4gglund M. Prevention of acute knee injuries in adolescent female football players: cluster randomised controlled trial. BMJ. 2012;344: e3042. https:\/\/doi.org\/10.1136\/bmj.e3042.","journal-title":"BMJ"},{"issue":"5","key":"1797_CR10","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1111\/j.1600-0838.2007.00703.x","volume":"18","author":"K Steffen","year":"2008","unstructured":"Steffen K, Myklebust G, Olsen OE, Holme I, Bahr R. Preventing injuries in female youth football\u2014a cluster-randomized controlled trial. Scand J Med Sci Sports. 2008;18(5):605\u201314. https:\/\/doi.org\/10.1111\/j.1600-0838.2007.00703.x.","journal-title":"Scand J Med Sci Sports"},{"issue":"337","key":"1797_CR11","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a2469","volume":"9","author":"T Soligard","year":"2008","unstructured":"Soligard T, Myklebust G, Steffen K, Holme I, Silvers H, Bizzini M, et al. Comprehensive warm-up programme to prevent injuries in young female footballers: cluster randomised controlled trial. BMJ. 2008;9(337): a2469. https:\/\/doi.org\/10.1136\/bmj.a2469.","journal-title":"BMJ"},{"issue":"8","key":"1797_CR12","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1136\/bjsm.2010.074377","volume":"44","author":"CA Emery","year":"2010","unstructured":"Emery CA, Meeuwisse WH. The effectiveness of a neuromuscular prevention strategy to reduce injuries in youth soccer: a cluster-randomised controlled trial. Br J Sports Med. 2010;44(8):555\u201362. https:\/\/doi.org\/10.1136\/bjsm.2010.074377.","journal-title":"Br J Sports Med"},{"issue":"6","key":"1797_CR13","doi-asserted-by":"publisher","first-page":"1493","DOI":"10.1007\/s40279-017-0834-8","volume":"48","author":"R R\u00f6ssler","year":"2018","unstructured":"R\u00f6ssler R, Junge A, Bizzini M, Verhagen E, Chomiak J, Aus der F\u00fcnten K, et al. A multinational cluster randomised controlled trial to assess the efficacy of \u201c11+ Kids\u201d: a warm-up programme to prevent injuries in children\u2019s football. Sports Med. 2018;48(6):1493\u2013504. https:\/\/doi.org\/10.1007\/s40279-017-0834-8.","journal-title":"Sports Med"},{"issue":"7","key":"1797_CR14","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1136\/bjsports-2016-097066","volume":"51","author":"K Thorborg","year":"2017","unstructured":"Thorborg K, Krommes KK, Esteve E, Clausen MB, Bartels EM, Rathleff MS. Effect of specific exercise-based football injury prevention programmes on the overall injury rate in football: a systematic review and meta-analysis of the FIFA 11 and 11 + programmes. Br J Sports Med. 2017;51(7):562\u201371. https:\/\/doi.org\/10.1136\/bjsports-2016-097066.","journal-title":"Br J Sports Med"},{"issue":"2","key":"1797_CR15","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1007\/s40279-015-0404-x","volume":"46","author":"WS Al Attar","year":"2015","unstructured":"Al Attar WS, Soomro N, Pappas E, Sinclair PJ, Sanders RH. How effective are F-Marc Injury Prevention programs for soccer players? A systematic review and meta-analysis. Sports Med. 2015;46(2):205\u201317. https:\/\/doi.org\/10.1007\/s40279-015-0404-x.","journal-title":"Sports Med"},{"issue":"20","key":"1797_CR16","doi-asserted-by":"publisher","first-page":"1170","DOI":"10.1136\/bjsports-2020-103683","volume":"55","author":"IR Lemes","year":"2021","unstructured":"Lemes IR, Pinto RZ, Lage VN, Roch BAB, Verhagen E, Bolling C, et al. Do exercise-based prevention programmes reduce non-contact musculoskeletal injuries in football (soccer)? A systematic review and meta-analysis with 13 355 athletes and more than 1 million exposure hours. Br J Sports Med. 2021;55(20):1170\u20138. https:\/\/doi.org\/10.1136\/bjsports-2020-103683.","journal-title":"Br J Sports Med"},{"issue":"12","key":"1797_CR17","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1136\/bjsports-2018-099577","volume":"54","author":"A L\u00f3pez-Valenciano","year":"2020","unstructured":"L\u00f3pez-Valenciano A, Ruiz-P\u00e9rez I, Garcia-G\u00f3mez A, Vera-Garcia FJ, De Ste CM, Myer GD, et al. Epidemiology of injuries in professional football: a systematic review and meta-analysis. Br J Sports Med. 2020;54(12):711\u20138. https:\/\/doi.org\/10.1136\/bjsports-2018-099577.","journal-title":"Br J Sports Med"},{"key":"1797_CR18","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.jclinepi.2021.09.007","volume":"140","author":"FM Impellizzeri","year":"2021","unstructured":"Impellizzeri FM, McCall A, van Smeden M. Why methods matter in a meta-analysis: a reappraisal showed inconclusive injury preventive effect of Nordic hamstring exercise. J Clin Epidemiol. 2021;140:111\u201324. https:\/\/doi.org\/10.1016\/j.jclinepi.2021.09.007.","journal-title":"J Clin Epidemiol"},{"issue":"7","key":"1797_CR19","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-010247","volume":"6","author":"J IntHout","year":"2016","unstructured":"IntHout J, Ioannidis JP, Rovers MM, Goeman JJ. Plea for routinely presenting prediction intervals in meta-analysis. BMJ Open. 2016;6(7): e010247. https:\/\/doi.org\/10.1136\/bmjopen-2015-010247.","journal-title":"BMJ Open"},{"key":"1797_CR20","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71","volume":"372","author":"MJ Page","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372: n71. https:\/\/doi.org\/10.1136\/bmj.n71.","journal-title":"BMJ"},{"key":"1797_CR21","doi-asserted-by":"publisher","first-page":"d5928","DOI":"10.1136\/bmj.d5928","volume":"343","author":"JP Higgins","year":"2011","unstructured":"Higgins JP, Altman DG, G\u00f8tzsche PC, J\u00fcni P, Moher D, Oxman AD, Cochrane Bias Methods Group; Cochrane Statistical Methods Group, et al. The Cochrane Collaboration\u2019s tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928. https:\/\/doi.org\/10.1136\/bmj.d5928.","journal-title":"BMJ"},{"issue":"7454","key":"1797_CR22","doi-asserted-by":"publisher","first-page":"1490","DOI":"10.1136\/bmj.328.7454.1490","volume":"328","author":"D Atkins","year":"2004","unstructured":"Atkins D, Best D, Briss PA, Eccles M, Falck-Ytter Y, Flottorp S, GRADE Working Group, et al. Grading quality of evidence and strength of recommendations. BMJ. 2004;328(7454):1490. https:\/\/doi.org\/10.1136\/bmj.328.7454.1490.","journal-title":"BMJ"},{"issue":"1","key":"1797_CR23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/2046-4053-3-82","volume":"3","author":"N Meader","year":"2014","unstructured":"Meader N, King K, Llewellyn A, Norman G, Brown J, Rodgers M, et al. A checklist designed to aid consistency and reproducibility of GRADE assessments: development and pilot validation. Syst Rev. 2014;3(1):1\u20139. https:\/\/doi.org\/10.1186\/2046-4053-3-82.","journal-title":"Syst Rev"},{"issue":"7651","key":"1797_CR24","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1136\/bmj.39490.551019.BE","volume":"336","author":"GH Guyatt","year":"2008","unstructured":"Guyatt GH, Oxman AD, Kunz R, Vist GE, Falck-Ytter Y, Sch\u00fcnemann HJ, GRADE Working Group. What is \u201cquality of evidence\u201d and why is it important to clinicians? BMJ. 2008;336(7651):995\u20138. https:\/\/doi.org\/10.1136\/bmj.39490.551019.BE.","journal-title":"BMJ"},{"key":"1797_CR25","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f7450","volume":"348","author":"RL Grant","year":"2014","unstructured":"25. Grant RL. Converting an odds ratio to a range of plausible relative risks for better communication of research findings. BMJ. 2014;348: f7450. https:\/\/doi.org\/10.1136\/bmj.f7450.","journal-title":"BMJ"},{"key":"1797_CR26","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.socscimed.2017.05.049","volume":"186","author":"E Shor","year":"2017","unstructured":"Shor E, Roelfs D, Vang ZM. The \u201cHispanic mortality paradox\u201d revisited: meta-analysis and meta-regression of life-course differentials in Latin American and Caribbean immigrants\u2019 mortality. Soc Sci Med. 2017;186:20\u201333. https:\/\/doi.org\/10.1016\/j.socscimed.2017.05.049.","journal-title":"Soc Sci Med"},{"key":"1797_CR27","unstructured":"Higgins JPT, Green S. Cochrane handbook for systematic reviews of interventions. Version 5.1.0 [updated March 2011]. The Cochrane Collaboration; 2011."},{"issue":"7","key":"1797_CR28","doi-asserted-by":"publisher","first-page":"898","DOI":"10.1001\/jama.1993.03500070078033","volume":"269","author":"WW Fawzi","year":"1993","unstructured":"Fawzi WW, Chalmers TC, Herrera MG, Mosteller F. Vitamin A supplementation and child mortality: a meta-analysis. JAMA. 1993;269(7):898\u2013903. https:\/\/doi.org\/10.1001\/jama.1993.03500070078033.","journal-title":"JAMA"},{"key":"1797_CR29","unstructured":"Egger M, Davey-Smith G, Altman D, editors. Systematic reviews in health care: meta-analysis in context. New York: Wiley; 2008."},{"key":"1797_CR30","volume-title":"Introduction to meta-analysis","author":"M Borenstein","year":"2011","unstructured":"Borenstein M, Hedges LV, Higgins JP, Rothstein HR. Introduction to meta-analysis. New York: Wiley; 2011."},{"issue":"7109","key":"1797_CR31","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","volume":"315","author":"M Egger","year":"1997","unstructured":"Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629\u201334. https:\/\/doi.org\/10.1136\/bmj.315.7109.629.","journal-title":"BMJ"},{"issue":"4","key":"1797_CR32","doi-asserted-by":"publisher","first-page":"232596712110057","DOI":"10.1177\/23259671211005769","volume":"9","author":"M Hilska","year":"2021","unstructured":"Hilska M, Lepp\u00e4nen M, Vasankari T, Aaltonen S, Kannus P, Parkkari J, et al. Neuromuscular training warm-up prevents acute noncontact lower extremity injuries in children\u2019s soccer: a cluster randomized controlled trial. Orthop J Sports Med. 2021;9(4):23259671211005770. https:\/\/doi.org\/10.1177\/23259671211005769.","journal-title":"Orthop J Sports Med"},{"issue":"16","key":"1797_CR33","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1136\/bjsports-2012-091277","volume":"46","author":"AM van Beijsterveldt","year":"2012","unstructured":"van Beijsterveldt AM, van de Port IG, Krist MR, Schmikli SL, Stubbe JH, Frederiks JE, et al. Effectiveness of an injury prevention programme for adult male amateur soccer players: a cluster-randomised controlled trial. Br J Sports Med. 2012;46(16):1114\u20138. https:\/\/doi.org\/10.1136\/bjsports-2012-091277.","journal-title":"Br J Sports Med"},{"issue":"4","key":"1797_CR34","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1111\/sms.13353","volume":"29","author":"PA van de Hoef","year":"2019","unstructured":"van de Hoef PA, Brink MS, Huisstede BMA, van Smeden M, de Vries N, Goedhart EA, et al. Does a bounding exercise program prevent hamstring injuries in adult male soccer players? A cluster-RCT. Scand J Med Sci Sports. 2019;29(4):515\u201323. https:\/\/doi.org\/10.1111\/sms.13353.","journal-title":"Scand J Med Sci Sports"},{"issue":"10","key":"1797_CR35","doi-asserted-by":"publisher","first-page":"2447","DOI":"10.1007\/s11999-017-5342-5","volume":"475","author":"HJ Silvers-Granelli","year":"2017","unstructured":"Silvers-Granelli HJ, Bizzini M, Arundale A, Mandelbaum BR, Snyder-Mackler L. Does the FIFA 11 + injury prevention program reduce the incidence of ACL injury in male soccer players? Clin Orthop Relat Res. 2017;475(10):2447\u201355. https:\/\/doi.org\/10.1007\/s11999-017-5342-5.","journal-title":"Clin Orthop Relat Res"},{"issue":"2","key":"1797_CR36","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1136\/injuryprev-2015-041667","volume":"22","author":"CF Finch","year":"2016","unstructured":"Finch CF, Twomey DM, Fortington LV, Doyle TL, Elliott BC, Akram M, et al. Preventing Australian football injuries with a targeted neuromuscular control exercise programme: comparative injury rates from a training intervention delivered in a clustered randomised controlled trial. Inj Prev. 2016;22(2):123\u20138. https:\/\/doi.org\/10.1136\/injuryprev-2015-041667.","journal-title":"Inj Prev"},{"issue":"5","key":"1797_CR37","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0251839","volume":"16","author":"A Nuhu","year":"2021","unstructured":"Nuhu A, Jelsma J, Dunleavy K, Burgess T. Effect of the FIFA 11 + soccer specific warm up programme on the incidence of injuries: a cluster-randomised controlled trial. PLoS ONE. 2021;16(5): e0251839. https:\/\/doi.org\/10.1371\/journal.pone.0251839.","journal-title":"PLoS ONE"},{"issue":"2","key":"1797_CR38","first-page":"321","volume":"13","author":"OB Owoeye","year":"2014","unstructured":"Owoeye OB, Akinbo SR, Tella BA, Olawale OA. Efficacy of the FIFA 11 + warm-up programme in male youth football: a cluster randomised controlled trial. J Sports Sci Med. 2014;13(2):321\u20138.","journal-title":"J Sports Sci Med"},{"issue":"5","key":"1797_CR39","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/j.jsams.2019.12.001","volume":"23","author":"M Zarei","year":"2020","unstructured":"Zarei M, Abbasi H, Namazi P, Asgari M, Rommers N, R\u00f6ssler R. The 11+ Kids warm-up programme to prevent injuries in young Iranian male high-level football (soccer) players: a cluster-randomised controlled trial. J Sci Med Sport. 2020;23(5):469\u201374. https:\/\/doi.org\/10.1016\/j.jsams.2019.12.001.","journal-title":"J Sci Med Sport"},{"key":"1797_CR40","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d549","volume":"342","author":"RD Riley","year":"2011","unstructured":"40. Riley RD, Higgins JP, Deeks JJ. Interpretation of random effects meta-analyses. BMJ. 2011;342: d549. https:\/\/doi.org\/10.1136\/bmj.d549.","journal-title":"BMJ"},{"issue":"18","key":"1797_CR41","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1136\/bjsports-2019-101587","volume":"54","author":"KM Crossley","year":"2020","unstructured":"Crossley KM, Patterson BE, Culvenor AG, Bruder AM, Mosler AB, Mentiplay BF. Making football safer for women: a systematic review and meta-analysis of injury prevention programmes in 11 773 female football (soccer) players. Br J Sports Med. 2020;54(18):1089\u201398. https:\/\/doi.org\/10.1136\/bjsports-2019-101587.","journal-title":"Br J Sports Med"},{"issue":"14","key":"1797_CR42","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1136\/bjsports-2020-103430","volume":"55","author":"EH Wik","year":"2021","unstructured":"Wik EH, Lolli L, Chamari K, Materne O, Di Salvo V, Gregson W, et al. Injury patterns differ with age in male youth football: a four-season prospective study of 1111 time-loss injuries in an elite national academy. Br J Sports Med. 2021;55(14):794\u2013800. https:\/\/doi.org\/10.1136\/bjsports-2020-103430.","journal-title":"Br J Sports Med"},{"issue":"6","key":"1797_CR43","doi-asserted-by":"publisher","first-page":"1316","DOI":"10.1177\/0363546515574057","volume":"43","author":"N van der Horst","year":"2015","unstructured":"van der Horst N, Smits DW, Petersen J, Goedhart EA, Backx FJ. The preventive effect of the Nordic hamstring exercise on hamstring injuries in amateur soccer players: a randomized controlled trial. Am J Sports Med. 2015;43(6):1316\u201323. https:\/\/doi.org\/10.1177\/0363546515574057.","journal-title":"Am J Sports Med"}],"container-title":["Sports Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40279-022-01797-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40279-022-01797-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40279-022-01797-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T10:52:52Z","timestamp":1679568772000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40279-022-01797-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,8]]},"references-count":43,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["1797"],"URL":"https:\/\/doi.org\/10.1007\/s40279-022-01797-7","relation":{},"ISSN":["0112-1642","1179-2035"],"issn-type":[{"value":"0112-1642","type":"print"},{"value":"1179-2035","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,8]]},"assertion":[{"value":"21 November 2022","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 February 2023","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Open Access funding enabled and organized by Projekt DEAL.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"Rilind Ob\u00ebrtinca, Ilir Hoxha, Rina Meha, Arber Lama, Altina Bimbashi, Dorentina Kuqi, Bujar Shabani, Tim Meyer, and Karen aus der F\u00fcnten have no conflicts of interest that are directly relevant to the content of this article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest\/competing interests"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The datasets generated and\/or analyzed during the study implementation are available from the corresponding author upon request.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Availability of data and material"}},{"value":"Not applicable.","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code availability"}},{"value":"RO, IH, and KadF conceived and designed the study. RO, IH, RM, AL, AB, DK, and BSH conducted the search, study selection, data extraction, and quality appraisal. IH analyzed the data. RO, IH, and KadF contributed to the interpretation of the data. RO drafted the manuscript with input from KadF and TM. All authors have read and approved the final manuscript.","order":9,"name":"Ethics","group":{"name":"EthicsHeading","label":"Authors\u2019 contributions"}}]}}