{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T02:13:21Z","timestamp":1792548801008,"version":"4.5.0"},"reference-count":179,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20220738"],"award-info":[{"award-number":["BK20220738"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Diagn Ther"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1007\/s40291-025-00776-8","type":"journal-article","created":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T19:25:35Z","timestamp":1743708335000},"page":"345-366","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Psoriasis: A Multidimensional Review of Onset, Progression, Treatment, and the Evolution of Disease Models"],"prefix":"10.1007","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1734-4670","authenticated-orcid":false,"given":"Yanhong","family":"Pan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jueyao","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tongyao","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yin","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,1]]},"reference":[{"issue":"5","key":"776_CR1","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1111\/ijd.14864","volume":"59","author":"S AlQassimi","year":"2020","unstructured":"AlQassimi S, AlBrashdi S, Galadari H, Hashim MJ. Global burden of psoriasis\u2014comparison of regional and global epidemiology, 1990 to 2017. Int J Dermatol. 2020;59(5):566\u201371.","journal-title":"Int J Dermatol"},{"issue":"1","key":"776_CR2","doi-asserted-by":"publisher","first-page":"e4","DOI":"10.1111\/bjd.15610","volume":"177","author":"C Griffiths","year":"2017","unstructured":"Griffiths C, van der Walt JM, Ashcroft DM, et al. The global state of psoriasis disease epidemiology: a workshop report. Br J Dermatol. 2017;177(1):e4\u20137.","journal-title":"Br J Dermatol"},{"issue":"10281","key":"776_CR3","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1016\/S0140-6736(20)32549-6","volume":"397","author":"C Griffiths","year":"2021","unstructured":"Griffiths C, Armstrong AW, Gudjonsson JE, Barker J. Psoriasis. Lancet. 2021;397(10281):1301\u201315.","journal-title":"Lancet"},{"issue":"10275","key":"776_CR4","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1016\/S0140-6736(21)00184-7","volume":"397","author":"K Ghoreschi","year":"2021","unstructured":"Ghoreschi K, Balato A, Enerb\u00e4ck C, Sabat R. Therapeutics targeting the IL-23 and IL-17 pathway in psoriasis. Lancet. 2021;397(10275):754\u201366.","journal-title":"Lancet"},{"issue":"1","key":"776_CR5","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1038\/s41392-022-01059-y","volume":"7","author":"L Cheng","year":"2022","unstructured":"Cheng L, Wang S, Peng C, et al. Human umbilical cord mesenchymal stem cells for psoriasis: a phase 1\/2a, single-arm study. Signal Transduct Target Ther. 2022;7(1):263.","journal-title":"Signal Transduct Target Ther"},{"key":"776_CR6","doi-asserted-by":"publisher","DOI":"10.1172\/JCI160451","author":"Q Li","year":"2023","unstructured":"Li Q, Shao S, Zhu Z, et al. An IGFBP7hi endothelial cell subset drives T cell extravasation in psoriasis via endothelial glycocalyx degradation. J Clin Invest. 2023. https:\/\/doi.org\/10.1172\/JCI160451.","journal-title":"J Clin Invest"},{"issue":"18","key":"776_CR7","doi-asserted-by":"publisher","first-page":"488","DOI":"10.21037\/atm.2019.09.05","volume":"7","author":"Y Ru","year":"2019","unstructured":"Ru Y, Yan XN, Yang SQ, et al. Oral Taodan granules for mild-to-moderate psoriasis vulgaris: protocol for a randomized, double-blind, multicenter clinical trial. Ann Transl Med. 2019;7(18):488.","journal-title":"Ann Transl Med."},{"issue":"3","key":"776_CR8","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.1021\/acs.jproteome.0c00646","volume":"20","author":"G Castaldo","year":"2021","unstructured":"Castaldo G, Pagano I, Grimaldi M, et al. Effect of very-low-calorie ketogenic diet on psoriasis patients: a nuclear magnetic resonance-based metabolomic study. J Proteome Res. 2021;20(3):1509\u201321.","journal-title":"J Proteome Res"},{"key":"776_CR9","doi-asserted-by":"publisher","first-page":"4706865","DOI":"10.1155\/2019\/4706865","volume":"2019","author":"Y Wang","year":"2019","unstructured":"Wang Y, Fu Y, Zhang L, et al. Acupuncture needling, electroacupuncture, and fire needling improve imiquimod-induced psoriasis-like skin lesions through reducing local inflammatory responses. Evid Based Complement Alternat Med. 2019;2019:4706865.","journal-title":"Evid Based Complement Alternat Med"},{"issue":"1","key":"776_CR10","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1186\/s13063-019-3475-4","volume":"20","author":"J Deng","year":"2019","unstructured":"Deng J, Lu C, Xiang Y, et al. Auricular acupressure as a complementary therapy for psoriasis vulgaris: study protocol for a multicenter randomized controlled trial. Trials. 2019;20(1):358.","journal-title":"Trials"},{"issue":"2","key":"776_CR11","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1111\/1346-8138.17049","volume":"51","author":"A Morita","year":"2023","unstructured":"Morita A, Saeki H. Pediatric psoriasis: understanding pathological conditions and advances in treatment. J Dermatol. 2023;51(2):185\u201395.","journal-title":"J Dermatol"},{"issue":"19","key":"776_CR12","doi-asserted-by":"publisher","first-page":"1945","DOI":"10.1001\/jama.2020.4006","volume":"323","author":"AW Armstrong","year":"2020","unstructured":"Armstrong AW, Read C. Pathophysiology, clinical presentation, and treatment of psoriasis: a review. JAMA. 2020;323(19):1945\u201360.","journal-title":"JAMA"},{"issue":"5","key":"776_CR13","doi-asserted-by":"publisher","first-page":"1366","DOI":"10.1038\/jid.2012.490","volume":"133","author":"N Setta-Kaffetzi","year":"2013","unstructured":"Setta-Kaffetzi N, Navarini AA, Patel VM, et al. Rare pathogenic variants in IL36RN underlie a spectrum of psoriasis-associated pustular phenotypes. J Invest Dermatol. 2013;133(5):1366\u20139.","journal-title":"J Invest Dermatol"},{"issue":"Suppl 1","key":"776_CR14","doi-asserted-by":"publisher","first-page":"S43","DOI":"10.1007\/s00403-002-0371-6","volume":"295","author":"Y Umezawa","year":"2003","unstructured":"Umezawa Y, Ozawa A, Kawasima T, et al. Therapeutic guidelines for the treatment of generalized pustular psoriasis (GPP) based on a proposed classification of disease severity. Arch Dermatol Res. 2003;295(Suppl 1):S43-54.","journal-title":"Arch Dermatol Res"},{"issue":"9","key":"776_CR15","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1080\/1744666X.2019.1648209","volume":"15","author":"MJ Gooderham","year":"2019","unstructured":"Gooderham MJ, Van Voorhees AS, Lebwohl MG. An update on generalized pustular psoriasis. Expert Rev Clin Immunol. 2019;15(9):907\u201319.","journal-title":"Expert Rev Clin Immunol"},{"key":"776_CR16","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1111\/bjd.21627","volume":"187","author":"R Ramessur","year":"2022","unstructured":"Ramessur R, Corbett M, Marshall D, et al. Biomarkers of disease progression in people with psoriasis: a scoping review. Br J Dermatol. 2022;187:481\u201393.","journal-title":"Br J Dermatol"},{"issue":"6","key":"776_CR17","doi-asserted-by":"publisher","first-page":"1617","DOI":"10.1016\/j.jid.2021.08.446","volume":"142","author":"K Douroudis","year":"2022","unstructured":"Douroudis K, Ramessur R, Barbosa IA, Baudry D, Duckworth M, Angit C, et al. Differences in clinical features and comorbid burden between HLA-C\u221706:02 carrier groups in >9,000 people with psoriasis. J Invest Dermatol. 2022;142(6):1617-28.e10.","journal-title":"J Invest Dermatol"},{"key":"776_CR18","doi-asserted-by":"publisher","first-page":"1196323","DOI":"10.3389\/fmolb.2023.1196323","volume":"10","author":"C Cruz","year":"2023","unstructured":"Cruz C, Yang CC. Clinical application of serum biomarkers for detecting and monitoring of chronic plaque psoriasis. Front Mol Biosci. 2023;10:1196323.","journal-title":"Front Mol Biosci"},{"key":"776_CR19","doi-asserted-by":"publisher","first-page":"6971","DOI":"10.1038\/s41598-025-91532-9","volume":"15","author":"CA Guzm\u00e1n-Mart\u00edn","year":"2025","unstructured":"Guzm\u00e1n-Mart\u00edn CA, Jim\u00e9nez-Ortega RF, Ortega-Springall MF, et al. miR-16-5p, miR-21-5p, and miR-155-5p in circulating vesicles as psoriasis biomarkers. Sci Rep. 2025;15:6971.","journal-title":"Sci Rep"},{"issue":"5","key":"776_CR20","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1016\/j.clindermatol.2010.12.002","volume":"29","author":"D Hirokawa","year":"2011","unstructured":"Hirokawa D, Lee JB. Dermatoscopy: an overview of subsurface morphology. Clin Dermatol. 2011;29(5):557\u201365.","journal-title":"Clin Dermatol"},{"issue":"2","key":"776_CR21","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1111\/jocd.15926","volume":"23","author":"Y Wu","year":"2024","unstructured":"Wu Y, Sun L. Clinical value of dermoscopy in psoriasis. J Cosmet Dermatol. 2024;23(2):370\u201381.","journal-title":"J Cosmet Dermatol"},{"issue":"6","key":"776_CR22","doi-asserted-by":"publisher","first-page":"1198","DOI":"10.1111\/j.1365-2133.2012.10868.x","volume":"166","author":"A Lallas","year":"2012","unstructured":"Lallas A, Kyrgidis A, Tzellos TG, et al. Accuracy of dermoscopic criteria for the diagnosis of psoriasis, dermatitis, lichen planus and pityriasis rosea. Br J Dermatol. 2012;166(6):1198\u2013205.","journal-title":"Br J Dermatol"},{"issue":"6","key":"776_CR23","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1111\/srt.12726","volume":"25","author":"LP Aggarwal","year":"2019","unstructured":"Aggarwal LP. Data augmentation in dermatology image recognition using machine learning. Skin Res Technol. 2019;25(6):815.","journal-title":"Skin Res Technol"},{"key":"776_CR24","doi-asserted-by":"publisher","first-page":"7541583","DOI":"10.1155\/2022\/7541583","volume":"2022","author":"SF Aijaz","year":"2022","unstructured":"Aijaz SF, Khan SJ, Azim F, Shakeel CS, Hassan U. Deep learning application for effective classification of different types of psoriasis. J Healthc Eng. 2022;2022:7541583.","journal-title":"J Healthc Eng."},{"issue":"2","key":"776_CR25","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1364\/BOE.10.000879","volume":"10","author":"S Kim","year":"2019","unstructured":"Kim S, Kim J, Hwang M, et al. Smartphone-based multispectral imaging and machine-learning based analysis for discrimination between seborrheic dermatitis and psoriasis on the scalp. Biomed Opt Express. 2019;10(2):879\u201391.","journal-title":"Biomed Opt Express"},{"key":"776_CR26","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1111\/jdv.15965","volume":"34","author":"S Zhao","year":"2020","unstructured":"Zhao S, Xie B, Li Y, et al. Smart identification of psoriasis by images using convolutional neural networks: a case study in China. J Eur Acad Dermatol Venereol. 2020;34:518\u201324.","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"776_CR27","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.cmpb.2018.01.027","volume":"159","author":"A Pal","year":"2018","unstructured":"Pal A, Garain U, Chandra A, et al. Psoriasis skin biopsy image segmentation using deep convolutional neural network. Comput Methods Programs Biomed. 2018;159:59\u201369.","journal-title":"Comput Methods Programs Biomed"},{"key":"776_CR28","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1016\/j.bspc.2019.04.002","volume":"52","author":"M Dash","year":"2019","unstructured":"Dash M, Londhe ND, Ghosh S, et al. PsLSNet: automated psoriasis skin lesion segmentation using modified U-Net-based fully convolutional network. Biomed Signal Process Control. 2019;52:226\u201337.","journal-title":"Biomed Signal Process Control"},{"key":"776_CR29","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1111\/bjd.18741","volume":"182","author":"S Emam","year":"2020","unstructured":"Emam S, Du AX, Surmanowicz P, et al. Predicting the long-term outcomes of biologics in patients with psoriasis using machine learning. Br J Dermatol. 2020;182:1305\u20137.","journal-title":"Br J Dermatol"},{"issue":"8","key":"776_CR30","doi-asserted-by":"publisher","first-page":"1934","DOI":"10.3390\/biomedicines10081934","volume":"10","author":"C Antonatos","year":"2022","unstructured":"Antonatos C, Grafanaki K, Asmenoudi P, et al. Contribution of the environment, epigenetic mechanisms and non-coding RNAs in psoriasis. Biomedicines. 2022;10(8):1934.","journal-title":"Biomedicines"},{"key":"776_CR31","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.jaut.2015.07.008","volume":"64","author":"JL Harden","year":"2015","unstructured":"Harden JL, Krueger JG, Bowcock AM. The immunogenetics of psoriasis: a comprehensive review. J Autoimmun. 2015;64:66\u201373.","journal-title":"J Autoimmun"},{"issue":"15","key":"776_CR32","doi-asserted-by":"publisher","first-page":"11877","DOI":"10.1074\/jbc.M010512200","volume":"276","author":"J Bertin","year":"2001","unstructured":"Bertin J, Wang L, Guo Y, et al. CARD11 and CARD14 are novel caspase recruitment domain (CARD)\/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B. J Biol Chem. 2001;276(15):11877\u201382.","journal-title":"J Biol Chem"},{"issue":"7","key":"776_CR33","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1056\/NEJMoa1013068","volume":"365","author":"S Marrakchi","year":"2011","unstructured":"Marrakchi S, Guigue P, Renshaw BR, et al. Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis. N Engl J Med. 2011;365(7):620\u20138.","journal-title":"N Engl J Med"},{"issue":"5","key":"776_CR34","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1086\/503821","volume":"78","author":"RP Nair","year":"2006","unstructured":"Nair RP, Stuart PE, Nistor I, et al. Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene. Am J Hum Genet. 2006;78(5):827\u201351.","journal-title":"Am J Hum Genet"},{"key":"776_CR35","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.gene.2018.09.042","volume":"683","author":"S Singh","year":"2019","unstructured":"Singh S, Pradhan D, Puri P, et al. Genomic alterations driving psoriasis pathogenesis. Gene. 2019;683:61\u201371.","journal-title":"Gene"},{"issue":"6","key":"776_CR36","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1038\/jhg.2011.33","volume":"56","author":"Y Vasilopoulos","year":"2011","unstructured":"Vasilopoulos Y, Sagoo GS, Cork MJ, Walters K, Tazi-Ahnini R. HLA-C, CSTA and DS12346 susceptibility alleles confer over 100-fold increased risk of developing psoriasis: evidence of gene interaction. J Hum Genet. 2011;56(6):423\u20137.","journal-title":"J Hum Genet"},{"issue":"11","key":"776_CR37","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1136\/jmg.2008.065029","volume":"46","author":"U H\u00fcffmeier","year":"2009","unstructured":"H\u00fcffmeier U, Lascorz J, Becker T, et al. Characterisation of psoriasis susceptibility locus 6 (PSORS6) in patients with early onset psoriasis and evidence for interaction with PSORS1. J Med Genet. 2009;46(11):736\u201344.","journal-title":"J Med Genet"},{"key":"776_CR38","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2022.102916","volume":"133","author":"J Yu","year":"2022","unstructured":"Yu J, Zhao Q, Wang X, et al. Pathogenesis, multi-omics research, and clinical treatment of psoriasis. J Autoimmun. 2022;133: 102916.","journal-title":"J Autoimmun"},{"issue":"9","key":"776_CR39","doi-asserted-by":"publisher","first-page":"4874","DOI":"10.3390\/ijms23094874","volume":"23","author":"C Moltrasio","year":"2022","unstructured":"Moltrasio C, Romagnuolo M, Marzano AV. Epigenetic mechanisms of epidermal differentiation. Int J Mol Sci. 2022;23(9):4874.","journal-title":"Int J Mol Sci"},{"issue":"4","key":"776_CR40","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1016\/j.jid.2015.12.029","volume":"136","author":"F Zhou","year":"2016","unstructured":"Zhou F, Wang W, Shen C, et al. Epigenome-wide association analysis identified nine skin DNA methylation loci for psoriasis. J Invest Dermatol. 2016;136(4):779\u201387.","journal-title":"J Invest Dermatol"},{"issue":"1","key":"776_CR41","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.jdermsci.2021.11.007","volume":"105","author":"J Xian","year":"2022","unstructured":"Xian J, Shang M, Dai Y, et al. N6-methyladenosine-modified long non-coding RNA AGAP2-AS1 promotes psoriasis pathogenesis via miR-424-5p\/AKT3 axis. J Dermatol Sci. 2022;105(1):27\u201336.","journal-title":"J Dermatol Sci"},{"issue":"6","key":"776_CR42","doi-asserted-by":"publisher","first-page":"2021","DOI":"10.1016\/j.jaci.2021.11.024","volume":"149","author":"L Yang","year":"2022","unstructured":"Yang L, Fu J, Han X, et al. Hsa_circ_0004287 inhibits macrophage-mediated inflammation in an N6-methyladenosine-dependent manner in atopic dermatitis and psoriasis. J Allergy Clin Immunol. 2022;149(6):2021\u201333.","journal-title":"J Allergy Clin Immunol"},{"issue":"17","key":"776_CR43","doi-asserted-by":"publisher","first-page":"9294","DOI":"10.3390\/ijms22179294","volume":"22","author":"K Dopytalska","year":"2021","unstructured":"Dopytalska K, Ciechanowicz P, Wiszniewski K, Szyma\u0144ska E, Walecka I. The role of epigenetic factors in psoriasis. Int J Mol Sci. 2021;22(17):9294.","journal-title":"Int J Mol Sci"},{"issue":"12","key":"776_CR44","doi-asserted-by":"publisher","first-page":"1361","DOI":"10.1111\/exd.13790","volume":"27","author":"MC Ovejero-Benito","year":"2018","unstructured":"Ovejero-Benito MC, Reolid A, S\u00e1nchez-Jim\u00e9nez P, et al. Histone modifications associated with biological drug response in moderate-to-severe psoriasis. Exp Dermatol. 2018;27(12):1361\u201371.","journal-title":"Exp Dermatol"},{"issue":"4","key":"776_CR45","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.202215674","volume":"15","author":"MJ Wang","year":"2023","unstructured":"Wang MJ, Huang HJ, Xu YY, et al. Metabolic rewiring in keratinocytes by miR-31-5p identifies therapeutic intervention for psoriasis. EMBO Mol Med. 2023;15(4): e15674.","journal-title":"EMBO Mol Med"},{"issue":"3","key":"776_CR46","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.jdermsci.2022.02.001","volume":"105","author":"Y Liu","year":"2022","unstructured":"Liu Y, Zhao X, Li J, et al. MiR-155 inhibits TP53INP1 expression leading to enhanced glycolysis of psoriatic mesenchymal stem cells. J Dermatol Sci. 2022;105(3):142\u201351.","journal-title":"J Dermatol Sci"},{"issue":"4","key":"776_CR47","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1007\/s40291-022-00598-y","volume":"26","author":"HY Abdallah","year":"2022","unstructured":"Abdallah HY, Tawfik NZ, Soliman NH, Eldeen L. The lncRNA PRINS-miRNA-mRNA axis gene expression profile as a circulating biomarker panel in psoriasis. Mol Diagn Ther. 2022;26(4):451\u201365.","journal-title":"Mol Diagn Ther"},{"issue":"1","key":"776_CR48","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1084\/jem.20050500","volume":"202","author":"FO Nestle","year":"2005","unstructured":"Nestle FO, Conrad C, Tun-Kyi A, et al. Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production. J Exp Med. 2005;202(1):135\u201343.","journal-title":"J Exp Med"},{"issue":"5","key":"776_CR49","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.1016\/j.jaci.2021.04.021","volume":"148","author":"J Kim","year":"2021","unstructured":"Kim J, Lee J, Kim HJ, et al. Single-cell transcriptomics applied to emigrating cells from psoriasis elucidate pathogenic versus regulatory immune cell subsets. J Allergy Clin Immunol. 2021;148(5):1281\u201392.","journal-title":"J Allergy Clin Immunol"},{"issue":"8","key":"776_CR50","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2023.112910","volume":"42","author":"L Zhu","year":"2023","unstructured":"Zhu L, Xia X, Li G, et al. SLC38A5 aggravates DC-mediated psoriasiform skin inflammation via potentiating lysosomal acidification. Cell Rep. 2023;42(8): 112910.","journal-title":"Cell Rep"},{"issue":"12","key":"776_CR51","doi-asserted-by":"publisher","first-page":"3167","DOI":"10.1016\/j.jid.2022.06.006","volume":"142","author":"R Tanaka","year":"2022","unstructured":"Tanaka R, Ichimura Y, Kubota N, et al. The role of PD-L1 on langerhans cells in the regulation of psoriasis. J Invest Dermatol. 2022;142(12):3167-3174.e9.","journal-title":"J Invest Dermatol"},{"issue":"7","key":"776_CR52","doi-asserted-by":"publisher","first-page":"1912","DOI":"10.1038\/jid.2014.98","volume":"134","author":"R Yoshiki","year":"2014","unstructured":"Yoshiki R, Kabashima K, Honda T, et al. IL-23 from Langerhans cells is required for the development of imiquimod-induced psoriasis-like dermatitis by induction of IL-17A-producing \u03b3\u03b4 T cells. J Invest Dermatol. 2014;134(7):1912\u201321.","journal-title":"J Invest Dermatol"},{"key":"776_CR53","doi-asserted-by":"publisher","first-page":"4953","DOI":"10.4049\/jimmunol.1500551","volume":"195","author":"D Terhorst","year":"2015","unstructured":"Terhorst D, Chelbi R, Wohn C, et al. Dynamics and transcriptomics of skin dendritic cells and macrophages in an imiquimod-induced, biphasic mouse model of psoriasis. J Immunol. 2015;195:4953\u201361.","journal-title":"J Immunol"},{"issue":"10","key":"776_CR54","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.15252\/emmm.201404114","volume":"6","author":"E Glitzner","year":"2014","unstructured":"Glitzner E, Korosec A, Brunner PM, et al. Specific roles for dendritic cell subsets during initiation and progression of psoriasis. EMBO Mol Med. 2014;6(10):1312\u201327.","journal-title":"EMBO Mol Med"},{"key":"776_CR55","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2021.100963","volume":"80","author":"C De Pasquale","year":"2021","unstructured":"De Pasquale C, Campana S, Bonaccorsi I, Carrega P, Ferlazzo G. ILC in chronic inflammation, cancer and targeting with biologicals. Mol Aspects Med. 2021;80: 100963.","journal-title":"Mol Aspects Med"},{"issue":"4","key":"776_CR56","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1111\/bjd.12067","volume":"168","author":"T Gambichler","year":"2013","unstructured":"Gambichler T, Zhang Y, H\u00f6xtermann S, Kreuter A. Natural killer cells and B lymphocytes in peripheral blood of patients with psoriasis. Br J Dermatol. 2013;168(4):894\u20136.","journal-title":"Br J Dermatol"},{"issue":"3","key":"776_CR57","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1111\/bjd.12658","volume":"170","author":"B Dyring-Andersen","year":"2014","unstructured":"Dyring-Andersen B, Geisler C, Agerbeck C, et al. Increased number and frequency of group 3 innate lymphoid cells in nonlesional psoriatic skin. Br J Dermatol. 2014;170(3):609\u201316.","journal-title":"Br J Dermatol"},{"issue":"7852","key":"776_CR58","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1038\/s41586-021-03188-w","volume":"592","author":"P Bielecki","year":"2021","unstructured":"Bielecki P, Riesenfeld SJ, H\u00fctter JC, et al. Skin-resident innate lymphoid cells converge on a pathogenic effector state. Nature. 2021;592(7852):128\u201332.","journal-title":"Nature"},{"issue":"23","key":"776_CR59","doi-asserted-by":"publisher","first-page":"10483","DOI":"10.7150\/thno.45614","volume":"10","author":"C Qie","year":"2020","unstructured":"Qie C, Jiang J, Liu W, et al. Single-cell RNA-Seq reveals the transcriptional landscape and heterogeneity of skin macrophages in Vsir-\/- murine psoriasis. Theranostics. 2020;10(23):10483\u201397.","journal-title":"Theranostics."},{"issue":"8","key":"776_CR60","doi-asserted-by":"publisher","first-page":"2105","DOI":"10.1172\/JCI27180","volume":"116","author":"H Wang","year":"2006","unstructured":"Wang H, Peters T, Kess D, et al. Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation. J Clin Invest. 2006;116(8):2105\u201314.","journal-title":"J Clin Invest"},{"issue":"3","key":"776_CR61","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.202114455","volume":"14","author":"Y Zhu","year":"2022","unstructured":"Zhu Y, Wu Z, Yan W, et al. Allosteric inhibition of SHP2 uncovers aberrant TLR7 trafficking in aggravating psoriasis. EMBO Mol Med. 2022;14(3): e14455.","journal-title":"EMBO Mol Med"},{"issue":"1","key":"776_CR62","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1038\/s41420-023-01444-8","volume":"9","author":"RZ Tan","year":"2023","unstructured":"Tan RZ, Zhong X, Han RY, et al. Macrophages mediate psoriasis via Mincle-dependent mechanism in mice. Cell Death Discov. 2023;9(1):140.","journal-title":"Cell Death Discov"},{"issue":"7702","key":"776_CR63","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1038\/s41586-018-0052-z","volume":"556","author":"M Bambouskova","year":"2018","unstructured":"Bambouskova M, Gorvel L, Lampropoulou V, et al. Electrophilic properties of itaconate and derivatives regulate the I\u03baB\u03b6-ATF3 inflammatory axis. Nature. 2018;556(7702):501\u20134.","journal-title":"Nature"},{"issue":"3","key":"776_CR64","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1038\/s41556-022-00853-8","volume":"24","author":"LL Chen","year":"2022","unstructured":"Chen LL, Morcelle C, Cheng ZL, et al. Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses. Nat Cell Biol. 2022;24(3):353\u201363.","journal-title":"Nat Cell Biol"},{"key":"776_CR65","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2024.103176","volume":"144","author":"J Yang","year":"2024","unstructured":"Yang J, Zhang S, Wu Q, et al. T cell-mediated skin-brain axis: bridging the gap between psoriasis and psychiatric comorbidities. J Autoimmun. 2024;144: 103176.","journal-title":"J Autoimmun"},{"issue":"1","key":"776_CR66","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/S0002-9440(10)65109-7","volume":"155","author":"BJ Nickoloff","year":"1999","unstructured":"Nickoloff BJ, Wrone-Smith T. Injection of pre-psoriatic skin with CD4+ T cells induces psoriasis. Am J Pathol. 1999;155(1):145\u201358.","journal-title":"Am J Pathol"},{"issue":"5","key":"776_CR67","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.1111\/bjd.12812","volume":"170","author":"F Kono","year":"2014","unstructured":"Kono F, Honda T, Aini W, Manabe T, Haga H, Tsuruyama T. Interferon-\u03b3\/CCR5 expression in invariant natural killer T cells and CCL5 expression in capillary veins of dermal papillae correlate with development of psoriasis vulgaris. Br J Dermatol. 2014;170(5):1048\u201355.","journal-title":"Br J Dermatol"},{"issue":"1","key":"776_CR68","doi-asserted-by":"publisher","first-page":"3878","DOI":"10.1038\/s41467-023-39484-4","volume":"14","author":"A Fries","year":"2023","unstructured":"Fries A, Saidoune F, Kuonen F, et al. Differentiation of IL-26+ TH17 intermediates into IL-17A producers via epithelial crosstalk in psoriasis. Nat Commun. 2023;14(1):3878.","journal-title":"Nat Commun"},{"key":"776_CR69","doi-asserted-by":"publisher","first-page":"2158","DOI":"10.3389\/fimmu.2019.02158","volume":"10","author":"M Di Giovangiulio","year":"2019","unstructured":"Di Giovangiulio M, Rizzo A, Franz\u00e8 E, et al. Tbet expression in regulatory T cells is required to initiate Th1-mediated colitis. Front Immunol. 2019;10:2158.","journal-title":"Front Immunol"},{"key":"776_CR70","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1111\/j.1600-065X.2007.00565.x","volume":"220","author":"YY Wan","year":"2007","unstructured":"Wan YY, Flavell RA. \u201cYin-Yang\u201d functions of transforming growth factor-beta and T regulatory cells in immune regulation. Immunol Rev. 2007;220:199\u2013213.","journal-title":"Immunol Rev"},{"issue":"1","key":"776_CR71","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.clim.2009.11.008","volume":"135","author":"L Zhang","year":"2010","unstructured":"Zhang L, Yang XQ, Cheng J, Hui RS, Gao TW. Increased Th17 cells are accompanied by FoxP3(+) Treg cell accumulation and correlated with psoriasis disease severity. Clin Immunol. 2010;135(1):108\u201317.","journal-title":"Clin Immunol"},{"issue":"13","key":"776_CR72","doi-asserted-by":"publisher","first-page":"3564","DOI":"10.1016\/j.celrep.2018.12.012","volume":"25","author":"T Hartwig","year":"2018","unstructured":"Hartwig T, Zwicky P, Schreiner B, et al. Regulatory T cells restrain pathogenic T helper cells during skin inflammation. Cell Rep. 2018;25(13):3564-3572.e4.","journal-title":"Cell Rep"},{"issue":"8","key":"776_CR73","doi-asserted-by":"publisher","first-page":"1844","DOI":"10.1016\/j.immuni.2023.06.021","volume":"56","author":"P Sivasami","year":"2023","unstructured":"Sivasami P, Elkins C, Diaz-Saldana PP, et al. Obesity-induced dysregulation of skin-resident PPAR\u03b3+ Treg cells promotes IL-17A-mediated psoriatic inflammation. Immunity. 2023;56(8):1844-1861.e6.","journal-title":"Immunity"},{"issue":"14","key":"776_CR74","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2221255120","volume":"120","author":"P Zarin","year":"2023","unstructured":"Zarin P, Shwartz Y, Ortiz-Lopez A, et al. Treg cells require Izumo1R to regulate \u03b3\u03b4T cell-driven inflammation in the skin. Proc Natl Acad Sci U S A. 2023;120(14): e2221255120.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"776_CR75","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.aav8995","author":"MM Klicznik","year":"2019","unstructured":"Klicznik MM, Morawski PA, H\u00f6llbacher B, et al. Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy individuals. Sci Immunol. 2019. https:\/\/doi.org\/10.1126\/sciimmunol.aav8995.","journal-title":"Sci Immunol"},{"issue":"2","key":"776_CR76","doi-asserted-by":"publisher","DOI":"10.1002\/ctm2.1568","volume":"14","author":"P Liu","year":"2024","unstructured":"Liu P, Li L, Kuang Y, et al. The CD147 expression in CD4+ T cells is a novel biomarker for predicting efficacy of IL-17A inhibitor and psoriasis recurrence. Clin Transl Med. 2024;14(2): e1568.","journal-title":"Clin Transl Med"},{"issue":"77","key":"776_CR77","doi-asserted-by":"publisher","first-page":"eabq3254","DOI":"10.1126\/sciimmunol.abq3254","volume":"7","author":"SK Whitley","year":"2022","unstructured":"Whitley SK, Li M, Kashem SW, et al. Local IL-23 is required for proliferation and retention of skin-resident memory TH17 cells. Sci Immunol. 2022;7(77):eabq3254.","journal-title":"Sci Immunol"},{"issue":"4","key":"776_CR78","doi-asserted-by":"publisher","first-page":"1444","DOI":"10.1016\/j.jaci.2018.08.048","volume":"143","author":"I Gallais S\u00e9r\u00e9zal","year":"2019","unstructured":"Gallais S\u00e9r\u00e9zal I, Hoffer E, Ignatov B, et al. A skewed pool of resident T cells triggers psoriasis-associated tissue responses in never-lesional skin from patients with psoriasis. J Allergy Clin Immunol. 2019;143(4):1444\u201354.","journal-title":"J Allergy Clin Immunol"},{"issue":"91","key":"776_CR79","doi-asserted-by":"publisher","first-page":"eadi2848","DOI":"10.1126\/sciimmunol.adi2848","volume":"9","author":"D Wu","year":"2024","unstructured":"Wu D, Hailer AA, Wang S, et al. A single-cell atlas of IL-23 inhibition in cutaneous psoriasis distinguishes clinical response. Sci Immunol. 2024;9(91):eadi2848.","journal-title":"Sci Immunol."},{"issue":"1","key":"776_CR80","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1038\/jid.2011.259","volume":"132","author":"S Morizane","year":"2012","unstructured":"Morizane S, Yamasaki K, M\u00fchleisen B, et al. Cathelicidin antimicrobial peptide LL-37 in psoriasis enables keratinocyte reactivity against TLR9 ligands. J Invest Dermatol. 2012;132(1):135\u201343.","journal-title":"J Invest Dermatol"},{"issue":"1","key":"776_CR81","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/j.immuni.2020.06.004","volume":"53","author":"F Lou","year":"2020","unstructured":"Lou F, Sun Y, Xu Z, et al. Excessive polyamine generation in keratinocytes promotes self-RNA sensing by dendritic cells in psoriasis. Immunity. 2020;53(1):204-216.e10.","journal-title":"Immunity"},{"issue":"7","key":"776_CR82","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2024.114513","volume":"43","author":"J Jiang","year":"2024","unstructured":"Jiang J, Shao X, Liu W, et al. The mechano-chemical circuit in fibroblasts and dendritic cells drives basal cell proliferation in psoriasis. Cell Rep. 2024;43(7): 114513.","journal-title":"Cell Rep"},{"issue":"1","key":"776_CR83","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1182\/blood-2002-12-3793","volume":"102","author":"YP Xia","year":"2003","unstructured":"Xia YP, Li B, Hylton D, Detmar M, Yancopoulos GD, Rudge JS. Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis. Blood. 2003;102(1):161\u20138.","journal-title":"Blood"},{"issue":"4","key":"776_CR84","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1161\/ATVBAHA.118.312246","volume":"39","author":"MS Garshick","year":"2019","unstructured":"Garshick MS, Barrett TJ, Wechter T, et al. Inflammasome signaling and impaired vascular health in psoriasis. Arterioscler Thromb Vasc Biol. 2019;39(4):787\u201398.","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"776_CR85","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.589726","volume":"11","author":"L Chen","year":"2020","unstructured":"Chen L, Li J, Zhu W, et al. Skin and gut microbiome in psoriasis: gaining insight into the pathophysiology of it and finding novel therapeutic strategies. Front Microbiol. 2020;11: 589726.","journal-title":"Front Microbiol"},{"key":"776_CR86","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3389\/fcimb.2019.00007","volume":"9","author":"M Visser","year":"2019","unstructured":"Visser M, Kell DB, Pretorius E. Bacterial dysbiosis and translocation in psoriasis vulgaris. Front Cell Infect Microbiol. 2019;9:7.","journal-title":"Front Cell Infect Microbiol"},{"issue":"6","key":"776_CR87","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1111\/bjd.17931","volume":"181","author":"C Hidalgo-Cantabrana","year":"2019","unstructured":"Hidalgo-Cantabrana C, G\u00f3mez J, Delgado S, et al. Gut microbiota dysbiosis in a cohort of patients with psoriasis. Br J Dermatol. 2019;181(6):1287\u201395.","journal-title":"Br J Dermatol"},{"issue":"7","key":"776_CR88","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2023.112713","volume":"42","author":"K Sonomoto","year":"2023","unstructured":"Sonomoto K, Song R, Eriksson D, et al. High-fat-diet-associated intestinal microbiota exacerbates psoriasis-like inflammation by enhancing systemic \u03b3\u03b4 T cell IL-17 production. Cell Rep. 2023;42(7): 112713.","journal-title":"Cell Rep"},{"issue":"7","key":"776_CR89","doi-asserted-by":"publisher","first-page":"1780","DOI":"10.1016\/j.jid.2020.11.032","volume":"141","author":"Z Shi","year":"2021","unstructured":"Shi Z, Wu X, Santos Rocha C, et al. Short-term western diet intake promotes IL-23-mediated skin and joint inflammation accompanied by changes to the gut microbiota in mice. J Invest Dermatol. 2021;141(7):1780\u201391.","journal-title":"J Invest Dermatol"},{"key":"776_CR90","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.937539","volume":"13","author":"Q Qiu","year":"2022","unstructured":"Qiu Q, Deng J, Deng H, et al. Association of the characteristics of the blood metabolome and gut microbiome with the outcome of methotrexate therapy in psoriasis. Front Immunol. 2022;13: 937539.","journal-title":"Front Immunol"},{"issue":"5","key":"776_CR91","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1016\/j.immuni.2023.04.001","volume":"56","author":"R Bharadwaj","year":"2023","unstructured":"Bharadwaj R, Lusi CF, Mashayekh S, et al. Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity. Immunity. 2023;56(5):998-1012.e8.","journal-title":"Immunity"},{"issue":"8","key":"776_CR92","doi-asserted-by":"publisher","first-page":"1613","DOI":"10.1016\/j.jid.2022.12.026","volume":"143","author":"S Miura","year":"2023","unstructured":"Miura S, Ichimura Y, Sela U, et al. Staphylococcus aureus and Streptococcus pyogenes induce psoriasis-related transcriptomes augmented by IL-17A and TNF-\u03b1. J Invest Dermatol. 2023;143(8):1613-1617.e5.","journal-title":"J Invest Dermatol"},{"issue":"9","key":"776_CR93","doi-asserted-by":"publisher","first-page":"1657","DOI":"10.1016\/j.jid.2023.05.012","volume":"143","author":"Y Lai","year":"2023","unstructured":"Lai Y, Wu X, Chao E, et al. Impact of gut bacterial metabolites on psoriasis and psoriatic arthritis: current status and future perspectives. J Invest Dermatol. 2023;143(9):1657\u201366.","journal-title":"J Invest Dermatol"},{"issue":"8","key":"776_CR94","doi-asserted-by":"publisher","first-page":"2023","DOI":"10.1038\/jid.2013.92","volume":"133","author":"P Magiatis","year":"2013","unstructured":"Magiatis P, Pappas P, Gaitanis G, et al. Malassezia yeasts produce a collection of exceptionally potent activators of the Ah (dioxin) receptor detected in diseased human skin. J Invest Dermatol. 2013;133(8):2023\u201330.","journal-title":"J Invest Dermatol"},{"issue":"2","key":"776_CR95","doi-asserted-by":"publisher","first-page":"754","DOI":"10.7150\/thno.51154","volume":"11","author":"C Chen","year":"2021","unstructured":"Chen C, Hou G, Zeng C, Ren Y, Chen X, Peng C. Metabolomic profiling reveals amino acid and carnitine alterations as metabolic signatures in psoriasis. Theranostics. 2021;11(2):754\u201367.","journal-title":"Theranostics."},{"issue":"8","key":"776_CR96","doi-asserted-by":"publisher","first-page":"3339","DOI":"10.7150\/thno.93764","volume":"14","author":"W Liu","year":"2024","unstructured":"Liu W, Jiang J, Li Z, et al. Energy competition remodels the metabolic glucose landscape of psoriatic epidermal cells. Theranostics. 2024;14(8):3339\u201357.","journal-title":"Theranostics."},{"issue":"11","key":"776_CR97","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1136\/annrheumdis-2021-220168","volume":"80","author":"K Colaco","year":"2021","unstructured":"Colaco K, Lee KA, Akhtari S, et al. Targeted metabolomic profiling and prediction of cardiovascular events: a prospective study of patients with psoriatic arthritis and psoriasis. Ann Rheum Dis. 2021;80(11):1429\u201335.","journal-title":"Ann Rheum Dis"},{"issue":"10","key":"776_CR98","doi-asserted-by":"publisher","first-page":"5180","DOI":"10.1172\/JCI129269","volume":"130","author":"X Xia","year":"2020","unstructured":"Xia X, Cao G, Sun G, et al. GLS1-mediated glutaminolysis unbridled by MALT1 protease promotes psoriasis pathogenesis. J Clin Invest. 2020;130(10):5180\u201396.","journal-title":"J Clin Invest"},{"issue":"7","key":"776_CR99","doi-asserted-by":"publisher","first-page":"1665","DOI":"10.1016\/j.immuni.2024.04.022","volume":"57","author":"I Subudhi","year":"2024","unstructured":"Subudhi I, Konieczny P, Prystupa A, et al. Metabolic coordination between skin epithelium and type 17 immunity sustains chronic skin inflammation. Immunity. 2024;57(7):1665-1680.e7.","journal-title":"Immunity"},{"issue":"7","key":"776_CR100","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1038\/s41419-024-06887-0","volume":"15","author":"M Zhang","year":"2024","unstructured":"Zhang M, Li D, Zhu J, et al. IL-27 disturbs lipid metabolism and restrains mitochondrial activity to inhibit \u03b3\u03b4 T17 cell-mediated skin inflammation. Cell Death Dis. 2024;15(7):491.","journal-title":"Cell Death Dis"},{"issue":"3","key":"776_CR101","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/j.jdermsci.2018.11.009","volume":"92","author":"Y Zhou","year":"2018","unstructured":"Zhou Y, Follansbee T, Wu X, et al. TRPV1 mediates inflammation and hyperplasia in imiquimod (IMQ)-induced psoriasiform dermatitis (PsD) in mice. J Dermatol Sci. 2018;92(3):264\u201371.","journal-title":"J Dermatol Sci"},{"issue":"11","key":"776_CR102","doi-asserted-by":"publisher","first-page":"2221","DOI":"10.1016\/j.jid.2020.03.959","volume":"140","author":"SH Lee","year":"2020","unstructured":"Lee SH, Tonello R, Choi Y, Jung SJ, Berta T. Sensory neuron-expressed TRPC4 is a target for the relief of psoriasiform itch and skin inflammation in mice. J Invest Dermatol. 2020;140(11):2221-2229.e6.","journal-title":"J Invest Dermatol"},{"issue":"1","key":"776_CR103","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.jid.2022.08.034","volume":"143","author":"F De Logu","year":"2023","unstructured":"De Logu F, Maglie R, Titiz M, et al. miRNA-203b-3p induces acute and chronic pruritus through 5-HTR2B and TRPV4. J Invest Dermatol. 2023;143(1):142-153.e10.","journal-title":"J Invest Dermatol"},{"issue":"8","key":"776_CR104","doi-asserted-by":"publisher","first-page":"1774","DOI":"10.1016\/j.jid.2018.02.040","volume":"138","author":"\u00c1 Kem\u00e9ny","year":"2018","unstructured":"Kem\u00e9ny \u00c1, Kodji X, Horv\u00e1th S, et al. TRPA1 acts in a protective manner in imiquimod-induced psoriasiform dermatitis in mice. J Invest Dermatol. 2018;138(8):1774\u201384.","journal-title":"J Invest Dermatol"},{"issue":"24","key":"776_CR105","doi-asserted-by":"publisher","first-page":"4907","DOI":"10.1111\/bph.15673","volume":"178","author":"Y Pan","year":"2021","unstructured":"Pan Y, You Y, Sun L, et al. The STING antagonist H-151 ameliorates psoriasis via suppression of STING\/NF-\u03baB-mediated inflammation. Br J Pharmacol. 2021;178(24):4907\u201322.","journal-title":"Br J Pharmacol"},{"issue":"3 Pt B","key":"776_CR106","doi-asserted-by":"publisher","first-page":"898","DOI":"10.1016\/j.jid.2021.08.430","volume":"142","author":"Y Yu","year":"2022","unstructured":"Yu Y, Xue X, Tang W, Su L, Zhang L, Zhang Y. Cytosolic DNA-mediated STING-dependent inflammation contributes to the progression of psoriasis. J Invest Dermatol. 2022;142(3 Pt B):898-906.e4.","journal-title":"J Invest Dermatol"},{"issue":"5","key":"776_CR107","doi-asserted-by":"publisher","first-page":"2395","DOI":"10.4049\/jimmunol.1302120","volume":"192","author":"S Chiliveru","year":"2014","unstructured":"Chiliveru S, Rahbek SH, Jensen SK, et al. Inflammatory cytokines break down intrinsic immunological tolerance of human primary keratinocytes to cytosolic DNA. J Immunol. 2014;192(5):2395\u2013404.","journal-title":"J Immunol"},{"issue":"15","key":"776_CR108","volume":"6","author":"M Anastasiou","year":"2021","unstructured":"Anastasiou M, Newton GA, Kaur K, et al. Endothelial STING controls T cell transmigration in an IFNI-dependent manner. JCI Insight. 2021;6(15): e149346.","journal-title":"JCI Insight"},{"issue":"8","key":"776_CR109","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1111\/exd.14151","volume":"29","author":"A Luengas-Martinez","year":"2020","unstructured":"Luengas-Martinez A, Hardman-Smart J, Paus R, Young HS. Vascular endothelial growth factor-A as a promising therapeutic target for the management of psoriasis. Exp Dermatol. 2020;29(8):687\u201398.","journal-title":"Exp Dermatol"},{"issue":"4","key":"776_CR110","doi-asserted-by":"publisher","DOI":"10.1063\/5.0115827","volume":"6","author":"B Hang","year":"2022","unstructured":"Hang B, Jassem E, Mohammed H, Wan LQ, Herschkowitz JI, Fan J. Interacting with tumor cells weakens the intrinsic clockwise chirality of endothelial cells. APL Bioeng. 2022;6(4): 046107.","journal-title":"APL Bioeng"},{"issue":"10","key":"776_CR111","doi-asserted-by":"publisher","first-page":"eaat2111","DOI":"10.1126\/sciadv.aat2111","volume":"4","author":"J Fan","year":"2018","unstructured":"Fan J, Ray P, Lu YW, Kaur G, Schwarz JJ, Wan LQ. Cell chirality regulates intercellular junctions and endothelial permeability. Sci Adv. 2018;4(10):eaat2111.","journal-title":"Sci Adv"},{"issue":"1","key":"776_CR112","doi-asserted-by":"publisher","first-page":"6131","DOI":"10.1038\/s41467-024-50464-0","volume":"15","author":"Y Li","year":"2024","unstructured":"Li Y, Wang S, Zhang Y, et al. Ca2+ transients on the T cell surface trigger rapid integrin activation in a timescale of seconds. Nat Commun. 2024;15(1):6131.","journal-title":"Nat Commun"},{"issue":"4","key":"776_CR113","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1016\/j.jid.2023.09.281","volume":"144","author":"G Garcia","year":"2024","unstructured":"Garcia G, Chen SJ, Westerland MR, Wu X, Hwang ST, Simon SI. Psoriatic neutrophils are primed in circulation for enhanced \u03b22-integrin-dependent recruitment and effector function on E-selectin and ICAM-1. J Invest Dermatol. 2024;144(4):901-905.e4.","journal-title":"J Invest Dermatol"},{"issue":"19","key":"776_CR114","doi-asserted-by":"publisher","first-page":"2101","DOI":"10.1182\/blood-2017-05-783027","volume":"130","author":"VA Morikis","year":"2017","unstructured":"Morikis VA, Chase S, Wun T, Chaikof EL, Magnani JL, Simon SI. Selectin catch-bonds mechanotransduce integrin activation and neutrophil arrest on inflamed endothelium under shear flow. Blood. 2017;130(19):2101\u201310.","journal-title":"Blood"},{"issue":"2","key":"776_CR115","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1038\/nm0202-157","volume":"8","author":"B Homey","year":"2002","unstructured":"Homey B, Alenius H, M\u00fcller A, et al. CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nat Med. 2002;8(2):157\u201365.","journal-title":"Nat Med"},{"issue":"1","key":"776_CR116","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1038\/s41423-019-0291-4","volume":"17","author":"L Chen","year":"2020","unstructured":"Chen L, Shen Z. Tissue-resident memory T cells and their biological characteristics in the recurrence of inflammatory skin disorders. Cell Mol Immunol. 2020;17(1):64\u201375.","journal-title":"Cell Mol Immunol"},{"issue":"2","key":"776_CR117","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1016\/j.jaci.2020.04.034","volume":"147","author":"MP Sch\u00f6n","year":"2021","unstructured":"Sch\u00f6n MP, Manzke V, Erpenbeck L. Animal models of psoriasis-highlights and drawbacks. J Allergy Clin Immunol. 2021;147(2):439\u201355.","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"776_CR118","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.immuni.2018.05.012","volume":"49","author":"M Wang","year":"2018","unstructured":"Wang M, Zhang S, Zheng G, et al. Gain-of-function mutation of CARD14 leads to spontaneous psoriasis-like skin inflammation through enhanced keratinocyte response to IL-17A. Immunity. 2018;49(1):66-79.e5.","journal-title":"Immunity"},{"issue":"9","key":"776_CR119","doi-asserted-by":"publisher","first-page":"2010","DOI":"10.1016\/j.jid.2018.03.1525","volume":"138","author":"M Mellett","year":"2018","unstructured":"Mellett M, Meier B, Mohanan D, et al. CARD14 gain-of-function mutation alone is sufficient to drive IL-23\/IL-17-mediated psoriasiform skin inflammation in vivo. J Invest Dermatol. 2018;138(9):2010\u201323.","journal-title":"J Invest Dermatol"},{"issue":"3 Pt B","key":"776_CR120","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1016\/j.jid.2021.06.019","volume":"142","author":"RS Gangwar","year":"2022","unstructured":"Gangwar RS, Gudjonsson JE, Ward NL. Mouse models of psoriasis: a comprehensive review. J Invest Dermatol. 2022;142(3 Pt B):884\u201397.","journal-title":"J Invest Dermatol"},{"issue":"12","key":"776_CR121","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0145498","volume":"10","author":"X Wang","year":"2015","unstructured":"Wang X, Sun J, Hu J. IMQ induced K14-VEGF mouse: a stable and long-term mouse model of psoriasis-like inflammation. PLoS ONE. 2015;10(12): e0145498.","journal-title":"PLoS ONE"},{"key":"776_CR122","doi-asserted-by":"publisher","first-page":"1560","DOI":"10.1038\/ncomms2566","volume":"4","author":"A Walter","year":"2013","unstructured":"Walter A, Sch\u00e4fer M, Cecconi V, et al. Aldara activates TLR7-independent immune defence. Nat Commun. 2013;4:1560.","journal-title":"Nat Commun"},{"issue":"1","key":"776_CR123","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/s13073-017-0415-3","volume":"9","author":"WR Swindell","year":"2017","unstructured":"Swindell WR, Michaels KA, Sutter AJ, et al. Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis. Genome Med. 2017;9(1):24.","journal-title":"Genome Med."},{"issue":"3","key":"776_CR124","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1016\/j.jid.2016.10.024","volume":"137","author":"JE Hawkes","year":"2017","unstructured":"Hawkes JE, Gudjonsson JE, Ward NL. The snowballing literature on imiquimod-induced skin inflammation in mice: a critical appraisal. J Invest Dermatol. 2017;137(3):546\u20139.","journal-title":"J Invest Dermatol"},{"issue":"4533","key":"776_CR125","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1126\/science.7036342","volume":"215","author":"JE Fraki","year":"1982","unstructured":"Fraki JE, Briggaman RA, Lazarus GS. Uninvolved skin from psoriatic patients develops signs of involved psoriatic skin after being grafted onto nude mice. Science. 1982;215(4533):685\u20137.","journal-title":"Science"},{"issue":"3","key":"776_CR126","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1111\/j.0022-202X.2003.12602.x","volume":"122","author":"SP Raychaudhuri","year":"2004","unstructured":"Raychaudhuri SP, Sanyal M, Weltman H, Kundu-Raychaudhuri S. K252a, a high-affinity nerve growth factor receptor blocker, improves psoriasis: an in vivo study using the severe combined immunodeficient mouse-human skin model. J Invest Dermatol. 2004;122(3):812\u20139.","journal-title":"J Invest Dermatol"},{"issue":"11","key":"776_CR127","doi-asserted-by":"publisher","first-page":"2985","DOI":"10.3390\/cells10112985","volume":"10","author":"K Boche\u0144ska","year":"2021","unstructured":"Boche\u0144ska K, Moskot M, Gabig-Cimi\u0144ska M. Use of cytokine mix-, imiquimod-, and serum-induced monoculture and lipopolysaccharide- and interferon gamma-treated co-culture to establish in vitro psoriasis-like inflammation models. Cells. 2021;10(11):2985.","journal-title":"Cells"},{"issue":"7812","key":"776_CR128","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1038\/s41586-020-2352-3","volume":"582","author":"J Lee","year":"2020","unstructured":"Lee J, Rabbani CC, Gao H, et al. Hair-bearing human skin generated entirely from pluripotent stem cells. Nature. 2020;582(7812):399\u2013404.","journal-title":"Nature"},{"key":"776_CR129","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.050541","author":"J Scheurer","year":"2024","unstructured":"Scheurer J, Sauer B, Focken J, et al. Histological and functional characterization of 3D human skin models mimicking the inflammatory skin diseases psoriasis and atopic dermatitis. Dis Model Mech. 2024. https:\/\/doi.org\/10.1242\/dmm.050541.","journal-title":"Dis Model Mech"},{"issue":"34","key":"776_CR130","doi-asserted-by":"publisher","first-page":"E7101","DOI":"10.1073\/pnas.1700475114","volume":"114","author":"M Lei","year":"2017","unstructured":"Lei M, Schumacher LJ, Lai YC, et al. Self-organization process in newborn skin organoid formation inspires strategy to restore hair regeneration of adult cells. Proc Natl Acad Sci U S A. 2017;114(34):E7101\u201310.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"3","key":"776_CR131","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1016\/j.jid.2022.12.028","volume":"144","author":"N Golob-Schwarzl","year":"2024","unstructured":"Golob-Schwarzl N, Pilic J, Benezeder T, Bordag N, Painsi C, Wolf P. Eukaryotic initiation factor 4E (eIF4E) as a target of anti-psoriatic treatment. J Invest Dermatol. 2024;144(3):500-508.e3.","journal-title":"J Invest Dermatol"},{"issue":"11","key":"776_CR132","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1001\/jama.2022.15632","volume":"328","author":"MG Lebwohl","year":"2022","unstructured":"Lebwohl MG, Kircik LH, Moore AY, et al. Effect of roflumilast cream vs vehicle cream on chronic plaque psoriasis: the DERMIS-1 and DERMIS-2 randomized clinical trials. JAMA. 2022;328(11):1073\u201384.","journal-title":"JAMA"},{"issue":"4","key":"776_CR133","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1093\/bjd\/ljad182","volume":"189","author":"LH Kircik","year":"2023","unstructured":"Kircik LH, Alonso-Llamazares J, Bhatia N, et al. Once-daily roflumilast foam 0.3% for scalp and body psoriasis: a randomized, double-blind, vehicle-controlled phase IIb study. Br J Dermatol. 2023;189(4):392\u20139.","journal-title":"Br J Dermatol"},{"issue":"1","key":"776_CR134","doi-asserted-by":"publisher","first-page":"e24","DOI":"10.1111\/bjd.15779","volume":"178","author":"JH Lee","year":"2018","unstructured":"Lee JH, Jung YS, Kim GM, Bae JM. A hyaluronic acid-based microneedle patch to treat psoriatic plaques: a pilot open trial. Br J Dermatol. 2018;178(1):e24\u20135.","journal-title":"Br J Dermatol"},{"key":"776_CR135","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.colsurfb.2016.01.021","volume":"141","author":"H Bessar","year":"2016","unstructured":"Bessar H, Venditti I, Benassi L, et al. Functionalized gold nanoparticles for topical delivery of methotrexate for the possible treatment of psoriasis. Colloids Surf B Biointerfaces. 2016;141:141\u20137.","journal-title":"Colloids Surf B Biointerfaces"},{"key":"776_CR136","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1016\/j.jphotobiol.2016.05.023","volume":"161","author":"A Batycka-Baran","year":"2016","unstructured":"Batycka-Baran A, Besgen P, Wolf R, Szepietowski JC, Prinz JC. The effect of phototherapy on systemic inflammatory process in patients with plaque psoriasis. J Photochem Photobiol B. 2016;161:396\u2013401.","journal-title":"J Photochem Photobiol B"},{"issue":"6 Pt 1","key":"776_CR137","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1016\/S0190-9622(99)70076-9","volume":"40","author":"IB Walters","year":"1999","unstructured":"Walters IB, Burack LH, Coven TR, Gilleaudeau P, Krueger JG. Suberythemogenic narrow-band UVB is markedly more effective than conventional UVB in treatment of psoriasis vulgaris. J Am Acad Dermatol. 1999;40(6 Pt 1):893\u2013900.","journal-title":"J Am Acad Dermatol"},{"issue":"3","key":"776_CR138","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1016\/j.jaad.2019.04.042","volume":"81","author":"CA Elmets","year":"2019","unstructured":"Elmets CA, Lim HW, Stoff B, et al. Joint American Academy of Dermatology-National Psoriasis Foundation guidelines of care for the management and treatment of psoriasis with phototherapy. J Am Acad Dermatol. 2019;81(3):775\u2013804.","journal-title":"J Am Acad Dermatol"},{"key":"776_CR139","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.cyto.2016.08.014","volume":"101","author":"H Mitoma","year":"2018","unstructured":"Mitoma H, Horiuchi T, Tsukamoto H, Ueda N. Molecular mechanisms of action of anti-TNF-\u03b1 agents\u2014comparison among therapeutic TNF-\u03b1 antagonists. Cytokine. 2018;101:56\u201363.","journal-title":"Cytokine"},{"issue":"4","key":"776_CR140","doi-asserted-by":"publisher","first-page":"428","DOI":"10.4161\/mabs.12304","volume":"2","author":"DJ Shealy","year":"2010","unstructured":"Shealy DJ, Cai A, Staquet K, et al. Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor \u03b1. MAbs. 2010;2(4):428\u201339.","journal-title":"MAbs"},{"issue":"1","key":"776_CR141","doi-asserted-by":"publisher","first-page":"4741","DOI":"10.1038\/s41467-021-25066-9","volume":"12","author":"R Andres-Ejarque","year":"2021","unstructured":"Andres-Ejarque R, Ale HB, Grys K, et al. Enhanced NF-\u03baB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis. Nat Commun. 2021;12(1):4741.","journal-title":"Nat Commun"},{"key":"776_CR142","doi-asserted-by":"crossref","unstructured":"Comparison of biologic treatments in psoriasis using treatment duration. Br J Dermatol. 2023;189(5):e93.","DOI":"10.1093\/bjd\/ljad356"},{"issue":"8","key":"776_CR143","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0220868","volume":"14","author":"LM Sawyer","year":"2019","unstructured":"Sawyer LM, Malottki K, Sabry-Grant C, et al. Assessing the relative efficacy of interleukin-17 and interleukin-23 targeted treatments for moderate-to-severe plaque psoriasis: a systematic review and network meta-analysis of PASI response. PLoS ONE. 2019;14(8): e0220868.","journal-title":"PLoS ONE"},{"issue":"10","key":"776_CR144","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1056\/NEJMc1811317","volume":"380","author":"H Bachelez","year":"2019","unstructured":"Bachelez H, Choon SE, Marrakchi S, et al. Inhibition of the interleukin-36 pathway for the treatment of generalized pustular psoriasis. N Engl J Med. 2019;380(10):981\u20133.","journal-title":"N Engl J Med"},{"issue":"1","key":"776_CR145","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1111\/bjd.14685","volume":"176","author":"P Skendros","year":"2017","unstructured":"Skendros P, Papagoras C, Lefaki I, et al. Successful response in a case of severe pustular psoriasis after interleukin-1\u03b2 inhibition. Br J Dermatol. 2017;176(1):212\u20135.","journal-title":"Br J Dermatol"},{"issue":"1","key":"776_CR146","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1093\/bjd\/ljac021","volume":"188","author":"D Tha\u00e7i","year":"2023","unstructured":"Tha\u00e7i D, Vender R, de Rie MA, et al. Safety and efficacy of bimekizumab through 2 years in patients with moderate-to-severe plaque psoriasis: longer-term results from the BE SURE randomized controlled trial and the open-label extension from the BE BRIGHT trial. Br J Dermatol. 2023;188(1):22\u201331.","journal-title":"Br J Dermatol"},{"issue":"3","key":"776_CR147","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/j.jid.2016.11.022","volume":"137","author":"A Blauvelt","year":"2017","unstructured":"Blauvelt A. IL-6 differs from TNF-\u03b1: unpredicted clinical effects caused by IL-6 blockade in psoriasis. J Invest Dermatol. 2017;137(3):541\u20132.","journal-title":"J Invest Dermatol"},{"key":"776_CR148","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/964069","volume":"2014","author":"A Saggini","year":"2014","unstructured":"Saggini A, Chimenti S, Chiricozzi A. IL-6 as a druggable target in psoriasis: focus on pustular variants. J Immunol Res. 2014;2014: 964069.","journal-title":"J Immunol Res"},{"issue":"5","key":"776_CR149","doi-asserted-by":"publisher","first-page":"e202","DOI":"10.1111\/j.1365-2230.2008.02991.x","volume":"34","author":"A Akman","year":"2009","unstructured":"Akman A, Yilmaz E, Mutlu H, Ozdogan M. Complete remission of psoriasis following bevacizumab therapy for colon cancer. Clin Exp Dermatol. 2009;34(5):e202\u20134.","journal-title":"Clin Exp Dermatol"},{"issue":"6","key":"776_CR150","doi-asserted-by":"publisher","first-page":"632","DOI":"10.4103\/0019-5154.143574","volume":"59","author":"A Datta-Mitra","year":"2014","unstructured":"Datta-Mitra A, Riar NK, Raychaudhuri SP. Remission of psoriasis and psoriatic arthritis during bevacizumab therapy for renal cell cancer. Indian J Dermatol. 2014;59(6):632.","journal-title":"Indian J Dermatol"},{"issue":"50","key":"776_CR151","doi-asserted-by":"publisher","first-page":"21264","DOI":"10.1073\/pnas.0907550106","volume":"106","author":"HB Schonthaler","year":"2009","unstructured":"Schonthaler HB, Huggenberger R, Wculek SK, Detmar M, Wagner EF. Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis. Proc Natl Acad Sci U S A. 2009;106(50):21264\u20139.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"4","key":"776_CR152","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1016\/S1074-7613(00)00054-6","volume":"13","author":"M Karaghiosoff","year":"2000","unstructured":"Karaghiosoff M, Neubauer H, Lassnig C, et al. Partial impairment of cytokine responses in Tyk2-deficient mice. Immunity. 2000;13(4):549\u201360.","journal-title":"Immunity"},{"issue":"1","key":"776_CR153","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.jaad.2022.08.061","volume":"88","author":"B Strober","year":"2023","unstructured":"Strober B, Tha\u00e7i D, Sofen H, et al. Deucravacitinib versus placebo and apremilast in moderate to severe plaque psoriasis: efficacy and safety results from the 52-week, randomized, double-blinded, phase 3 program for evaluation of TYK2 inhibitor psoriasis second trial. J Am Acad Dermatol. 2023;88(1):40\u201351.","journal-title":"J Am Acad Dermatol"},{"issue":"11","key":"776_CR154","doi-asserted-by":"publisher","first-page":"2839","DOI":"10.1007\/s13555-023-01034-7","volume":"13","author":"AW Armstrong","year":"2023","unstructured":"Armstrong AW, Warren RB, Zhong Y, et al. Short-, mid-, and long-term efficacy of deucravacitinib versus biologics and nonbiologics for plaque psoriasis: a network meta-analysis. Dermatol Ther (Heidelb). 2023;13(11):2839\u201357.","journal-title":"Dermatol Ther (Heidelb)."},{"key":"776_CR155","doi-asserted-by":"publisher","first-page":"2589","DOI":"10.1007\/s13555-023-00977-1","volume":"13","author":"AW Armstrong","year":"2023","unstructured":"Armstrong AW, Park SH, Patel V, et al. Matching-adjusted indirect comparison of the long-term efficacy of deucravacitinib versus adalimumab for moderate to severe plaque psoriasis. Dermatol Ther (Heidelb). 2023;13:2589\u2013603.","journal-title":"Dermatol Ther (Heidelb)."},{"issue":"5","key":"776_CR156","doi-asserted-by":"publisher","first-page":"1763","DOI":"10.1007\/s13555-021-00596-8","volume":"11","author":"A Chimalakonda","year":"2021","unstructured":"Chimalakonda A, Burke J, Cheng L, et al. Selectivity profile of the tyrosine kinase 2 inhibitor deucravacitinib compared with janus kinase 1\/2\/3 inhibitors. Dermatol Ther (Heidelb). 2021;11(5):1763\u201376.","journal-title":"Dermatol Ther (Heidelb)."},{"issue":"3","key":"776_CR157","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/j.jaad.2022.06.657","volume":"87","author":"AW Armstrong","year":"2022","unstructured":"Armstrong AW, Warren RB, Safen H, Spelman L, Leonardi C, Banerjee S, Tao W, Throup J, Colston C, Napoli A, Kimball AB. 34658 Deucravacitinib, an oral, selective tyrosine kinase 2 (TYK2) inhibitor, in patients with moderate to severe plaque psoriasis who had inadequate responses to apremilast at week 24 in the phase 3 POETYK PSO-1 and PSO-2 trials. J Am Acad Dermatol. 2022;87(3):156.","journal-title":"J Am Acad Dermatol"},{"issue":"6","key":"776_CR158","doi-asserted-by":"publisher","first-page":"1168","DOI":"10.1111\/jdv.18925","volume":"37","author":"R Bissonnette","year":"2023","unstructured":"Bissonnette R, Saint-Cyr Proulx E, Jack C, Maari C. Tapinarof for psoriasis and atopic dermatitis: 15 years of clinical research. J Eur Acad Dermatol Venereol. 2023;37(6):1168\u201374.","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"1","key":"776_CR159","doi-asserted-by":"publisher","first-page":"9132","DOI":"10.1038\/s41598-021-88492-1","volume":"11","author":"S Liu","year":"2021","unstructured":"Liu S, Liu D, Shen R, et al. Discovery of a novel ROR\u03b3 antagonist with skin-restricted exposure for topical treatment of mild to moderate psoriasis. Sci Rep. 2021;11(1):9132.","journal-title":"Sci Rep"},{"issue":"10","key":"776_CR160","doi-asserted-by":"publisher","first-page":"3809","DOI":"10.4049\/jimmunol.1602142","volume":"198","author":"A Zanin-Zhorov","year":"2017","unstructured":"Zanin-Zhorov A, Weiss JM, Trzeciak A, et al. Cutting edge: selective oral ROCK2 inhibitor reduces clinical scores in patients with psoriasis vulgaris and normalizes skin pathology via concurrent regulation of IL-17 and IL-10. J Immunol. 2017;198(10):3809\u201314.","journal-title":"J Immunol"},{"issue":"22","key":"776_CR161","doi-asserted-by":"publisher","first-page":"15205","DOI":"10.1021\/acs.jmedchem.3c01297","volume":"66","author":"Y Huang","year":"2023","unstructured":"Huang Y, Mao CR, Lou Y, et al. Design, synthesis, and biological evaluation of an orally bioavailable, potent, and selective ROCK2 inhibitor for psoriasis treatment. J Med Chem. 2023;66(22):15205\u201329.","journal-title":"J Med Chem"},{"issue":"1","key":"776_CR162","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1021\/acsmedchemlett.8b00466","volume":"10","author":"T Siu","year":"2019","unstructured":"Siu T, Altman MD, Baltus GA, et al. Discovery of a novel cGAMP competitive ligand of the inactive form of STING. ACS Med Chem Lett. 2019;10(1):92\u20137.","journal-title":"ACS Med Chem Lett"},{"issue":"7","key":"776_CR163","doi-asserted-by":"publisher","first-page":"3127","DOI":"10.3390\/molecules28073127","volume":"28","author":"S Zhang","year":"2023","unstructured":"Zhang S, Zheng R, Pan Y, Sun H. Potential therapeutic value of the STING inhibitors. Molecules. 2023;28(7):3127.","journal-title":"Molecules"},{"issue":"4","key":"776_CR164","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1038\/gene.2010.75","volume":"12","author":"L Jin","year":"2011","unstructured":"Jin L, Xu LG, Yang IV, et al. Identification and characterization of a loss-of-function human MPYS variant. Genes Immun. 2011;12(4):263\u20139.","journal-title":"Genes Immun"},{"issue":"5","key":"776_CR165","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1111\/bjd.20517","volume":"185","author":"SM Lwin","year":"2021","unstructured":"Lwin SM, Snowden JA, Griffiths C. The promise and challenges of cell therapy for psoriasis. Br J Dermatol. 2021;185(5):887\u201398.","journal-title":"Br J Dermatol"},{"issue":"6","key":"776_CR166","first-page":"E7","volume":"95","author":"SM Sung","year":"2015","unstructured":"Sung SM, Kimball AB. Remission of psoriasis 13 years after autologous stem cell transplant. Cutis. 2015;95(6):E7-8.","journal-title":"Cutis"},{"issue":"11","key":"776_CR167","doi-asserted-by":"publisher","first-page":"2063","DOI":"10.3727\/096368916X691998","volume":"25","author":"MM De Jesus","year":"2016","unstructured":"De Jesus MM, Santiago JS, Trinidad CV, et al. Autologous adipose-derived mesenchymal stromal cells for the treatment of psoriasis vulgaris and psoriatic arthritis: a case report. Cell Transplant. 2016;25(11):2063\u20139.","journal-title":"Cell Transplant"},{"issue":"6","key":"776_CR168","doi-asserted-by":"publisher","first-page":"691","DOI":"10.2340\/00015555-1824","volume":"94","author":"P Jensen","year":"2014","unstructured":"Jensen P, Zachariae C, Christensen R, et al. Effect of weight loss on the cardiovascular risk profile of obese patients with psoriasis. Acta Derm Venereol. 2014;94(6):691\u20134.","journal-title":"Acta Derm Venereol"},{"issue":"1","key":"776_CR169","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1046\/j.1365-2133.2000.03240.x","volume":"142","author":"G Micha\u00eblsson","year":"2000","unstructured":"Micha\u00eblsson G, Gerd\u00e9n B, Hagforsen E, et al. Psoriasis patients with antibodies to gliadin can be improved by a gluten-free diet. Br J Dermatol. 2000;142(1):44\u201351.","journal-title":"Br J Dermatol"},{"key":"776_CR170","doi-asserted-by":"publisher","first-page":"6175","DOI":"10.2147\/JIR.S337031","volume":"14","author":"HL Chen","year":"2021","unstructured":"Chen HL, Zeng YB, Zhang ZY, et al. Gut and cutaneous microbiome featuring abundance of Lactobacillus reuteri protected against psoriasis-like inflammation in mice. J Inflamm Res. 2021;14:6175\u201390.","journal-title":"J Inflamm Res"},{"issue":"1","key":"776_CR171","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1097\/JD9.0000000000000074","volume":"3","author":"Committee of Psoriasis DB, Association CM","year":"2020","unstructured":"Committee of Psoriasis DB, Association CM. Guidelines for the diagnosis and treatment of psoriasis in China: 2019 concise edition. Int J Dermatol Venereol. 2020;3(1):14\u201326.","journal-title":"Int J Dermatol Venereol"},{"key":"776_CR172","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.629513","volume":"12","author":"X Zhang","year":"2021","unstructured":"Zhang X, Li X, Chen Y, et al. Xiao-Yin-Fang therapy alleviates psoriasis-like skin inflammation through suppressing \u03b3\u03b4T17 cell polarization. Front Pharmacol. 2021;12: 629513.","journal-title":"Front Pharmacol"},{"key":"776_CR173","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.649591","volume":"12","author":"Y Lu","year":"2021","unstructured":"Lu Y, Yang Y, Zhang J, et al. Anti-angiogenic efficacy of PSORI-CM02 and the associated mechanism in psoriasis in vitro and in vivo. Front Immunol. 2021;12: 649591.","journal-title":"Front Immunol"},{"key":"776_CR174","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.111884","volume":"141","author":"T Di","year":"2021","unstructured":"Di T, Zhao J, Wang Y, et al. Tuhuaiyin alleviates imiquimod-induced psoriasis via inhibiting the properties of IL-17-producing cells and remodels the gut microbiota. Biomed Pharmacother. 2021;141: 111884.","journal-title":"Biomed Pharmacother"},{"key":"776_CR175","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2024.117867","volume":"326","author":"Y Lin","year":"2024","unstructured":"Lin Y, Yin X, Ma S, et al. Cang-ai volatile oil ameliorates imiquimod-induced psoriatic skin lesions by suppressing the ILC3s. J Ethnopharmacol. 2024;326: 117867.","journal-title":"J Ethnopharmacol"},{"issue":"23","key":"776_CR176","doi-asserted-by":"publisher","first-page":"10466","DOI":"10.7150\/thno.45211","volume":"10","author":"Y Chen","year":"2020","unstructured":"Chen Y, Yan Y, Liu H, et al. Dihydroartemisinin ameliorates psoriatic skin inflammation and its relapse by diminishing CD8+ T-cell memory in wild-type and humanized mice. Theranostics. 2020;10(23):10466\u201382.","journal-title":"Theranostics."},{"issue":"5","key":"776_CR177","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.1111\/bjd.17852","volume":"181","author":"HJ Shi","year":"2019","unstructured":"Shi HJ, Zhou H, Ma AL, et al. Oxymatrine therapy inhibited epidermal cell proliferation and apoptosis in severe plaque psoriasis. Br J Dermatol. 2019;181(5):1028\u201337.","journal-title":"Br J Dermatol"},{"issue":"1","key":"776_CR178","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/j.apsb.2021.07.019","volume":"12","author":"L Xi","year":"2022","unstructured":"Xi L, Lin Z, Qiu F, et al. Enhanced uptake and anti-maturation effect of celastrol-loaded mannosylated liposomes on dendritic cells for psoriasis treatment. Acta Pharm Sin B. 2022;12(1):339\u201352.","journal-title":"Acta Pharm Sin B"},{"issue":"4","key":"776_CR179","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1067\/mjd.2002.124702","volume":"47","author":"DN Sauder","year":"2002","unstructured":"Sauder DN, Dekoven J, Champagne P, Croteau D, Dupont E. Neovastat (AE-941), an inhibitor of angiogenesis: randomized phase I\/II clinical trial results in patients with plaque psoriasis. J Am Acad Dermatol. 2002;47(4):535\u201341.","journal-title":"J Am Acad Dermatol"}],"container-title":["Molecular Diagnosis & Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40291-025-00776-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40291-025-00776-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40291-025-00776-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T20:02:09Z","timestamp":1746734529000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40291-025-00776-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,1]]},"references-count":179,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["776"],"URL":"https:\/\/doi.org\/10.1007\/s40291-025-00776-8","relation":{},"ISSN":["1177-1062","1179-2000"],"issn-type":[{"value":"1177-1062","type":"print"},{"value":"1179-2000","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,1]]},"assertion":[{"value":"2 March 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 April 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Natural Science Foundation of Jiangsu Province (BK20220738).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"Yanhong Pan, Jueyao Zou, Tongyao Hu, Ziyan Zhu, Zhengyu Zhang, Yin Lu, and Wenxing Chen have no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval and Consent to Participate"}},{"value":"No data were used for the research described in the article.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Data Availability Statement"}},{"value":"Yanhong Pan: Writing\u2014original draft; writing\u2014review and editing; investigation; funding acquisition. Jueyao Zou: Writing\u2014original draft; visualization. Tongyao Hu: Writing\u2014original draft; visualization. Ziyan Zhu: Investigation; software; visualization. Zhengyu Zhang: Software; visualization. Yin Lu: Supervision. Wenxing Chen: Supervision.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Author Contributions"}},{"value":"Not applicable.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent"}},{"value":"Not applicable.","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code Availability"}}]}}