{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T11:37:42Z","timestamp":1774438662731,"version":"3.50.1"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T00:00:00Z","timestamp":1670803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T00:00:00Z","timestamp":1670803200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100004586","name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["High Blood Press Cardiovasc Prev"],"DOI":"10.1007\/s40292-022-00555-0","type":"journal-article","created":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T12:14:55Z","timestamp":1670847295000},"page":"45-54","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Early Vascular Aging in Obese Individuals with Low Cardiovascular Health"],"prefix":"10.1007","volume":"30","author":[{"given":"Michelle Rabello","family":"Cunha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samanta","family":"Mattos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rcia R. S. T.","family":"Klein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0797-572X","authenticated-orcid":false,"given":"Mario Fritsch","family":"Neves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,12,12]]},"reference":[{"key":"555_CR1","doi-asserted-by":"publisher","first-page":"1161","DOI":"10.1038\/oby.2008.231","volume":"16","author":"DB Allison","year":"2008","unstructured":"Allison DB, Downey M, Atkinson RL, Billington CJ, Bray GA, Eckel RH, Finkelstein EA, Jensen MD, Tremblay A. Obesity as a disease: a white paper on evidence and arguments commissioned by the council of the obesity society. Obesity. 2008;16:1161\u201377.","journal-title":"Obesity"},{"key":"555_CR2","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1002\/oby.22378","volume":"27","author":"AM Jastreboff","year":"2019","unstructured":"Jastreboff AM, Kotz CM, Kahan S, Kelly AS, Heymsfield SB. Obesity as a disease: the obesity society 2018 position statement. Obesity. 2019;27:7\u20139.","journal-title":"Obesity"},{"key":"555_CR3","unstructured":"WHO. Obesity and overweight [Internet]. 2021. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/obesity-and-overweight. Accessed 7 Jul 2022"},{"key":"555_CR4","doi-asserted-by":"publisher","first-page":"E984","DOI":"10.1161\/CIR.0000000000000973","volume":"143","author":"TM Powell-Wiley","year":"2021","unstructured":"Powell-Wiley TM, Poirier P, Burke LE, Despr\u00e9s JP, Gordon-Larsen P, Lavie CJ. Obesity and cardiovascular disease: a scientific statement from the American heart association. Circulation. 2021;143:E984-1010.","journal-title":"Circulation"},{"key":"555_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13098-019-0468-0","volume":"11","author":"C Cercato","year":"2019","unstructured":"Cercato C, Fonseca FA. Cardiovascular risk and obesity. Diabetol Metab Syndr. 2019;11:1\u201315.","journal-title":"Diabetol Metab Syndr"},{"key":"555_CR6","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1161\/CIRCULATIONAHA.109.192703","volume":"121","author":"DM Lloyd-Jones","year":"2010","unstructured":"Lloyd-Jones DM, Hong Y, Labarthe D, Mozaffarian D, Appel LJ, Van Horn L, Lloyd-Jones LM, Hong Y, Labarthe D, Mozaffarian D, Appel J, Van Horn L, Greenlund K, Daniels S, Nichol G, Tomaselli GF, Arnett DK, Fonarow GC, Ho PM, Lauer MS, Masoudi FA, Robertson RM, Roger V, Schwamm LH, Sorlie P, Yancy CW, Rosamond WD. Defining and setting national goals for cardiovascular health promotion and disease reduction: The American heart association\u2019s strategic impact goal through 2020 and beyond. Circulation. 2010;121:586\u2013613.","journal-title":"Circulation"},{"issue":"5","key":"555_CR7","doi-asserted-by":"publisher","first-page":"e18","DOI":"10.1161\/CIR.0000000000001078","volume":"146","author":"DM Lloyd-Jones","year":"2022","unstructured":"Lloyd-Jones DM, Allen NB, Anderson CAM, Black T, Brewer LC, Foraker RE, Grandner MA, Lavretsky A, Perak AM, Sharma G, Rosamond A. Life\u2019s essential 8: updating and enhancing the American heart association\u2019s construct of cardiovascular health: a presidential advisory from the American heart association. Circulation. 2022;146(5):e18\u201343.","journal-title":"Circulation"},{"key":"555_CR8","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1002\/clc.22836","volume":"40","author":"L Guo","year":"2017","unstructured":"Guo L, Zhang S. Association between ideal cardiovascular health metrics and risk of cardiovascular events or mortality: a meta-analysis of prospective studies. Clin Cardiol. 2017;40:1339\u201346.","journal-title":"Clin Cardiol"},{"key":"555_CR9","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1016\/j.ijcard.2016.03.210","volume":"214","author":"N Fang","year":"2016","unstructured":"Fang N, Jiang M, Fan Y. Ideal cardiovascular health metrics and risk of cardiovascular disease or mortality: a meta-analysis. Int J Cardiol. 2016;214:279\u201383.","journal-title":"Int J Cardiol"},{"key":"555_CR10","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.871524","volume":"10","author":"R Kruger","year":"2022","unstructured":"Kruger R, Litwin M, Climie RE. Editorial: determinants and impact of early vascular aging in children and adolescents. Front Pediatr. 2022;10: 871524.","journal-title":"Front Pediatr"},{"key":"555_CR11","doi-asserted-by":"publisher","first-page":"2665","DOI":"10.1016\/S0140-6736(16)31134-5","volume":"388","author":"MH Olsen","year":"2016","unstructured":"Olsen MH, Angell SY, Asma S, Boutouyrie P, Burger D, Chirinos JA, Damasceno A, Delles C, Gimenez-Roqueplo AP, Hering D, L\u00f3pez-Jaramillo P, Martinez F, Perkovic V, Rietzschel ER, Schillaci G, Schutte AE, Scuteri A, Sharman JE, Wachtell K, Wang JG. A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on hypertension. Lancet. 2016;388:2665\u2013712.","journal-title":"Lancet"},{"key":"555_CR12","first-page":"137","volume-title":"Chapter 14: age-induced endothelial dysfunction and intima-media thickening","author":"PM Nilsson","year":"2015","unstructured":"Nilsson PM, Olsen MH, Laurent S. Early vascular aging (EVA). In: Kozakova M, Schmidt-Truks\u00e4ss A, editors. Chapter 14: age-induced endothelial dysfunction and intima-media thickening. New York: Academic Press; 2015. p. 137\u201345."},{"issue":"1","key":"555_CR13","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1161\/HYPERTENSIONAHA.109.129114","volume":"54","author":"PM Nilsson","year":"2009","unstructured":"Nilsson PM, Boutouyrie P, Laurent S. Vascular aging: a tale of EVA and ADAM in cardiovascular risk assessment and prevention. Hypertension. 2009;54(1):3\u201310.","journal-title":"Hypertension"},{"key":"555_CR14","doi-asserted-by":"publisher","first-page":"479","DOI":"10.5664\/jcsm.6506","volume":"13","author":"VK Kapur","year":"2017","unstructured":"Kapur VK, Auckley DH, Chowdhur S, Kuhlmann DC, Mehra R, Ramar K, Harrod CG. Clinical practice guideline for diagnostic testing for adult obstructive sleep Apnea: an American Academy of Sleep Medicine Clinical Practice Guideline. J Clin Sleep Med. 2017;13:479\u2013504.","journal-title":"J Clin Sleep Med"},{"key":"555_CR15","unstructured":"Task Force of the European Society of Cardiology the North American Society of Pacing Electrophysiology. Heart Rate Variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Circulation. 1996;93(5):1043\u201365."},{"key":"555_CR16","doi-asserted-by":"publisher","first-page":"1589","DOI":"10.1016\/j.mayocp.2018.05.035","volume":"93","author":"R Ram\u00edrez-V\u00e9lez","year":"2018","unstructured":"Ram\u00edrez-V\u00e9lez R, Saavedra JM, Lobelo F, Celis-Morales CA, Pozo-Cruz B, Garc\u00eda-Hermoso A. Ideal cardiovascular health and incident cardiovascular disease among adults: a systematic review and meta-analysis. Mayo Clin Proc. 2018;93:1589\u201399.","journal-title":"Mayo Clin Proc"},{"key":"555_CR17","doi-asserted-by":"publisher","first-page":"e139","DOI":"10.1161\/CIR.0000000000000757","volume":"141","author":"SS Virani","year":"2020","unstructured":"Virani SS. Heart disease and stroke statistics\u20142020 update: a report from the American Heart Association. Circulation. 2020;141:e139-596.","journal-title":"Circulation"},{"issue":"19","key":"555_CR18","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.017458","volume":"9","author":"B Gaye","year":"2020","unstructured":"Gaye B, Tajeu GS, Vasan RS, Lassale C, Allen NB, Singh-Manoux A. Association of changes in cardiovascular health metrics and risk of subsequent cardiovascular disease and mortality. J Am Heart Assoc. 2020;9(19): e017458.","journal-title":"J Am Heart Assoc"},{"issue":"6","key":"555_CR19","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1097\/01.hjr.0000214613.29608.f5","volume":"13","author":"M Akbartabartoori","year":"2006","unstructured":"Akbartabartoori M, Lean MEJ, Hankey CR. Smoking combined with overweight or obesity markedly elevates cardiovascular risk factors. Eur J Prev Cardiol. 2006;13(6):938\u201346.","journal-title":"Eur J Prev Cardiol"},{"issue":"5","key":"555_CR20","doi-asserted-by":"publisher","first-page":"427","DOI":"10.2174\/1573399813666170705161039","volume":"14","author":"J Iqbal","year":"2018","unstructured":"Iqbal J, Al Qarni A, Hawwari A, Alghanem AF, Ahmed G. Metabolic syndrome, dyslipidemia and regulation of lipoprotein metabolism. Curr Diabetes Rev. 2018;14(5):427\u201333.","journal-title":"Curr Diabetes Rev"},{"issue":"3","key":"555_CR21","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1157\/13116658","volume":"61","author":"CJ O\u2019Donnell","year":"2008","unstructured":"O\u2019Donnell CJ, Elosua R. Cardiovascular risk factors. Insights from Framingham heart study. Rev Esp Cardiol. 2008;61(3):299\u2013310.","journal-title":"Rev Esp Cardiol."},{"issue":"1","key":"555_CR22","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1186\/s12889-021-10871-0","volume":"21","author":"F Nie","year":"2021","unstructured":"Nie F, Wang Z, Zeng Q, Guan H, Yang J, Luo P, Du L, Wang J, Hong F. Health behaviors and metabolic risk factors are associated with dyslipidemia in ethnic Miao Chinese adults: the China multi-ethnic cohort study. BMC Public Health. 2021;21(1):851.","journal-title":"BMC Public Health"},{"key":"555_CR23","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.sleep.2018.12.028","volume":"57","author":"GR Geovanini","year":"2019","unstructured":"Geovanini GR, Lorenzi-Filho G, de Paula LK, Oliveira CM, de Oliveira AR, Beijamini F, Negr\u00e3o AB, von Schantz M, Knutson KL, Krieger JK, Pereira AC. Poor sleep quality and lipid profile in a rural cohort (The Baependi Heart Study). Sleep Med. 2019;57:30\u20135.","journal-title":"Sleep Med"},{"key":"555_CR24","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1093\/aje\/kwp230","volume":"170","author":"DS Lauderdale","year":"2009","unstructured":"Lauderdale DS, Knutson KL, Rathouz PJ, Yan LL, Hulley SB, Liu K. Cross-sectional and longitudinal associations between objectively measured sleep duration and body mass index. Am J Epidemiol. 2009;170:805\u201313.","journal-title":"Am J Epidemiol"},{"key":"555_CR25","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1097\/MCO.0b013e3283479109","volume":"14","author":"G Beccuti","year":"2011","unstructured":"Beccuti G, Pannain S. Sleep and obesity. Curr Opin Clin Nutr Metab Care. 2011;14:402\u201312.","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"555_CR26","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1093\/sleep\/30.2.219","volume":"30","author":"JR Jennings","year":"2007","unstructured":"Jennings JR, Muldoon MF, Hall M, Buysse DJ, Manuck SB. Self-reported sleep quality is associated with the metabolic syndrome. Sleep. 2007;30:219\u201323.","journal-title":"Sleep"},{"issue":"11","key":"555_CR27","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.5665\/sleep.3104","volume":"36","author":"MER Petrov","year":"2013","unstructured":"Petrov MER, Kim Y, Lauderdale D, Lewis CE, Reis JP, Carnethon MR, Knutson K, Stephen JG. Longitudinal associations between objective sleep and lipids: the CARDIA study. Sleep. 2013;36(11):1587\u201395.","journal-title":"Sleep"},{"key":"555_CR28","first-page":"152","volume":"46","author":"MJF Dobi\u00e1sov\u00e1","year":"2000","unstructured":"Dobi\u00e1sov\u00e1 MJF. The new atherogenic plasma index reflects the triglyceride and HDL-cholesterol ratio, the lipoprotein particle size and the cholesterol esterification rate: changes during Lipanor therapy. Vnitr Lek. 2000;46:152\u20136.","journal-title":"Vnitr Lek."},{"key":"555_CR29","doi-asserted-by":"crossref","unstructured":"National Cholesterol Education Program (U.S.). Expert Panel on Detection, Evaluation and T of HBC in A. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (adult Treatment Panel III) Final Report. JAMA. 2002;106(25):3143-421.","DOI":"10.1161\/circ.106.25.3143"},{"key":"555_CR30","doi-asserted-by":"publisher","first-page":"9900","DOI":"10.1038\/s41598-021-89307-z","volume":"11","author":"YW Li","year":"2021","unstructured":"Li YW, Kao TW, Chang PK, Chen WL, Wu LW. Atherogenic index of plasma as predictors for metabolic syndrome, hypertension and diabetes mellitus in Taiwan citizens: a 9-year longitudinal study. Sci Rep. 2021;11:9900.","journal-title":"Sci Rep"},{"key":"555_CR31","doi-asserted-by":"publisher","first-page":"7027624","DOI":"10.1155\/2018\/7027624","volume":"2018","author":"MS Bo","year":"2018","unstructured":"Bo MS, Cheah WL, Lwin S, Moe Nwe T, Win TT, Aung M. Understanding the relationship between atherogenic index of plasma and cardiovascular disease risk factors among staff of an University in Malaysia. J Nutr Metab. 2018;2018:7027624.","journal-title":"J Nutr Metab"},{"key":"555_CR32","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1097\/00005344-199200111-00002","volume":"20","author":"RA DeFronzo","year":"1992","unstructured":"DeFronzo RA. Insulin resistance, hyperinsulinemia, and coronary artery disease: a complex metabolic web. J Cardiovasc Pharmacol. 1992;20:S1-16.","journal-title":"J Cardiovasc Pharmacol"},{"issue":"10","key":"555_CR33","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1093\/ajh\/hpac057","volume":"35","author":"Y Suzuki","year":"2022","unstructured":"Suzuki Y, Kaneko H, Yano Y, Okada A, Itoh H, Matsuoka S, Fujiu K, Michihata N, Jo T, Takeda N, Morita H, Matsunaga A, Node K, McEvoy JW, Lam CSP, Oparil S, Yasunaga H, Komuro I. Association of cardiovascular health metrics with risk of transition to hypertension in non-hypertensive young adults. Am J Hypertens. 2022;35(10):858\u201366.","journal-title":"Am J Hypertens."},{"key":"555_CR34","doi-asserted-by":"publisher","first-page":"371","DOI":"10.2147\/VHRM.S316108","volume":"17","author":"NL Kang","year":"2021","unstructured":"Kang NL. Association between obesity and blood pressure in common korean people. Vasc Health Risk Manag. 2021;17:371\u20137.","journal-title":"Vasc Health Risk Manag."},{"key":"555_CR35","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1097\/HCO.0000000000000210","volume":"30","author":"LC Maclagan","year":"2015","unstructured":"Maclagan LC, Tu JV. Using the concept of ideal cardiovascular health to measure population health: a review. Curr Opin Cardiol. 2015;30:518\u201324.","journal-title":"Curr Opin Cardiol"},{"key":"555_CR36","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1016\/j.jacc.2009.10.061","volume":"55","author":"C Vlachopoulos","year":"2010","unstructured":"Vlachopoulos C, Aznaouridis K, Stefanadis C. Prediction of cardiovascular events and all-cause mortality with arterial stiffness. A systematic review and meta-analysis. J Am Coll Cardiol. 2010;55:1318\u201327.","journal-title":"J Am Coll Cardiol."},{"key":"555_CR37","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1038\/jhh.2013.131","volume":"28","author":"GE Crichton","year":"2014","unstructured":"Crichton GE, Elias MF, Robbins MA. Cardiovascular health and arterial stiffness: the Maine-Syracuse Longitudinal Study. J Hum Hypertens. 2014;28:444\u20139.","journal-title":"J Hum Hypertens"},{"key":"555_CR38","doi-asserted-by":"publisher","first-page":"1888","DOI":"10.1152\/japplphysiol.00521.2018","volume":"125","author":"MJ Rossman","year":"2018","unstructured":"Rossman MJ, LaRocca TJ, Martens CR, Seals DR. Healthy lifestyle-based approaches for successful vascular aging. J Appl Physiol. 2018;125:1888\u2013900.","journal-title":"J Appl Physiol"},{"key":"555_CR39","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/j.arr.2016.09.002","volume":"39","author":"TJ LaRocca","year":"2017","unstructured":"LaRocca TJ, Martens CR, Seals DR. Nutrition and other lifestyle influences on arterial aging. Ageing Res Rev. 2017;39:106\u201319.","journal-title":"Ageing Res Rev"},{"key":"555_CR40","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1002\/osp4.108","volume":"3","author":"JYA Ne","year":"2017","unstructured":"Ne JYA, Cai TY, Celermajer DS, Caterson ID, Gill T, Lee CMY, Skilton MR. Obesity, arterial function and arterial structure\u2014a systematic review and meta-analysis. Obes Sci Pract. 2017;3:171\u201384.","journal-title":"Obes Sci Pract"},{"key":"555_CR41","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1007\/s10554-010-9616-1","volume":"26","author":"Y Inaba","year":"2010","unstructured":"Inaba Y, Chen JA, Bergmann SR. Prediction of future cardiovascular outcomes by flow-mediated vasodilatation of brachial artery: a meta-analysis. Int J Cardiovasc Imaging. 2010;26:631\u201340.","journal-title":"Int J Cardiovasc Imaging"},{"key":"555_CR42","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1038\/oby.2007.201","volume":"15","author":"I Skrapari","year":"2007","unstructured":"Skrapari I, Tentolouris N, Perrea D, Bakoyiannis C, Papazafiropoulou A, Katsilambros N. Baroreflex sensitivity in obesity: relationship with cardiac autonomic nervous system activity. Obesity. 2007;15:1685\u201393.","journal-title":"Obesity"},{"key":"555_CR43","doi-asserted-by":"publisher","unstructured":"Taurio J, Hautaniemi E, Koskela1 JK, Er\u00e4ranta A, H\u00e4m\u00e4l\u00e4inen M, Tikkakoski A, Kettunen JA, K\u00e4h\u00f6nen M, Niemel\u00e4, Moilanen E, Mustonen J, P\u00f6rsti I. The characteristics of elevated blood pressure in abdominal obesity correspond to primary hypertension: a cross-sectional study. Res Sq. 2022;1\u201320. https:\/\/doi.org\/10.21203\/rs.3.rs-1970751\/v1","DOI":"10.21203\/rs.3.rs-1970751\/v1"}],"container-title":["High Blood Pressure & Cardiovascular Prevention"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40292-022-00555-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40292-022-00555-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40292-022-00555-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T13:14:27Z","timestamp":1675862067000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40292-022-00555-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,12]]},"references-count":43,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,1]]}},"alternative-id":["555"],"URL":"https:\/\/doi.org\/10.1007\/s40292-022-00555-0","relation":{},"ISSN":["1179-1985"],"issn-type":[{"value":"1179-1985","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,12]]},"assertion":[{"value":"16 October 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 November 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 December 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare the following financial interests:\u00a0Mario F Neves reports financial support was provided by Carlos Chagas Filho Foundation for Research Support of Rio de Janeiro State. Mario F Neves reports financial support was provided by National Council for Scientific and Technological Development.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding Statement"}},{"value":"The authors state that they have no conflicts of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest\/competing interest"}},{"value":"The datasets of the current study are available from the corresponding author on reasonable request.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Data availability"}},{"value":"MRC: conceptualization, conducting the research, specifically performing the data collection, writing\u2014original draft, interpretation and analysis of the data obtained. SM: conceptualization, conducting the research, specifically performing the data collection, interpretation and analysis of the data obtained. MRSTK: conceptualization, designed and performed the research, writing-original draft, interpretation and analysis of the data obtained, writing\u2014review and editing. MFN: conceptualization, designed and performed the research, made the statistical analyses, interpretation and analysis of the data obtained, writing\u2014review and editing. Acquisition of the financial support for the project leading to this publication.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Author contributions"}}]}}