{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T16:14:09Z","timestamp":1790957649585,"version":"4.1.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,3,11]],"date-time":"2023-03-11T00:00:00Z","timestamp":1678492800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2023,3,11]],"date-time":"2023-03-11T00:00:00Z","timestamp":1678492800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/501100011725","name":"Servier","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["High Blood Press Cardiovasc Prev"],"DOI":"10.1007\/s40292-023-00568-3","type":"journal-article","created":{"date-parts":[[2023,3,11]],"date-time":"2023-03-11T17:02:40Z","timestamp":1678554160000},"page":"167-173","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Impact of 2021 ESC Guidelines for Cardiovascular Disease Prevention on Hypertensive Patients Risk: Secondary Analysis of Save Your Heart Study"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4058-0655","authenticated-orcid":false,"given":"Rita","family":"Del Pinto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corrado","family":"Giua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Keber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora","family":"Grippa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Tilotta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Ferri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,3,11]]},"reference":[{"key":"568_CR1","doi-asserted-by":"publisher","first-page":"2982","DOI":"10.1016\/j.jacc.2020.11.010","volume":"76","author":"GA Roth","year":"2020","unstructured":"Roth GA, Mensah GA, Johnson CO, Addolorato G, Ammirati E, Baddour LM, et al. Global burden of cardiovascular diseases and risk factors, 1990\u20132019: update from the GBD 2019 study. J Am Coll Cardiol. 2020;76:2982\u20133021.","journal-title":"J Am Coll Cardiol"},{"key":"568_CR2","doi-asserted-by":"publisher","first-page":"e153","DOI":"10.1161\/CIR.0000000000001052","volume":"145","author":"CW Tsao","year":"2022","unstructured":"Tsao CW, Aday AW, Almarzooq ZI, Alonso A, Beaton AZ, Bittencourt MS, et al. Heart disease and stroke statistics-2022 update: a report from the American Heart Association. Circulation. 2022;145:e153\u2013639.","journal-title":"Circulation"},{"key":"568_CR3","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1016\/S0140-6736(20)30925-9","volume":"396","author":"GBD 2019 Diseases and Injuries Collaborators","year":"2020","unstructured":"GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990\u20132019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020;396:1204\u201322.","journal-title":"Lancet"},{"key":"568_CR4","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1007\/s40292-021-00465-7","volume":"28","author":"R Del Pinto","year":"2021","unstructured":"Del Pinto R, Desideri G, Ferri C, Agabiti RE. Real-world antihypertensive treatment patterns, treatment adherence, and blood pressure control in the elderly: an Italian awareness-raising campaign on hypertension by Senior Italia FederAnziani, the Italian Society of Hypertension and the Italian Federation of General Practitioners. High Blood Press Cardiovasc Prev. 2021;28:457\u201366.","journal-title":"High Blood Press Cardiovasc Prev."},{"key":"568_CR5","doi-asserted-by":"publisher","first-page":"3227","DOI":"10.1093\/eurheartj\/ehab484","volume":"42","author":"FLJ Visseren","year":"2021","unstructured":"Visseren FLJ, Mach F, Smulders YM, Carballo D, Koskinas KC, B\u00e4ck M, et al. 2021 ESC guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J. 2021;42:3227\u2013337.","journal-title":"Eur Heart J"},{"key":"568_CR6","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1001\/jama.2016.19043","volume":"317","author":"MH Forouzanfar","year":"2017","unstructured":"Forouzanfar MH, Liu P, Roth GA, Ng M, Biryukov S, Marczak L, et al. Global burden of hypertension and systolic blood pressure of at least 110 to 115 mmHg, 1990\u20132015. JAMA. 2017;317:165\u201382.","journal-title":"JAMA"},{"key":"568_CR7","doi-asserted-by":"publisher","first-page":"3021","DOI":"10.1093\/eurheartj\/ehy339","volume":"39","author":"B Williams","year":"2018","unstructured":"Williams B, Mancia G, Spiering W, Agabiti Rosei E, Azizi M, Burnier M, et al. 2018 ESC\/ESH guidelines for the management of arterial hypertension. Eur Heart J. 2018;39:3021\u2013104.","journal-title":"Eur Heart J"},{"key":"568_CR8","doi-asserted-by":"publisher","first-page":"2439","DOI":"10.1093\/eurheartj\/ehab309","volume":"42","author":"SCORE2 Working Group and ESC Cardiovascular Risk Collaboration","year":"2021","unstructured":"SCORE2 Working Group and ESC Cardiovascular Risk Collaboration. SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe. Eur Heart J. 2021;42:2439\u201354.","journal-title":"Eur Heart J"},{"key":"568_CR9","unstructured":"Save Your Heart\u2014Studio osservazionale trasversale, multicentrico, italiano, sulla presenza di fattori di rischio cardiovascolare in partecipanti affetti da ipertensione. [cited 12 Sep 2022]. Available: https:\/\/springerhealthcare.it\/GIHTAD\/2022\/02\/07\/save-your-heart-studio-osservazionale-trasversale-multicentrico-italiano-sulla-presenza-di-fattori-di-rischio-cardiovascolare-in-partecipanti-affetti-da-ipertensione\/."},{"key":"568_CR10","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1093\/eurheartj\/ehz455","volume":"41","author":"F Mach","year":"2020","unstructured":"Mach F, Baigent C, Catapano AL, Koskinas KC, Casula M, Badimon L, et al. 2019 ESC\/EAS guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk. Eur Heart J. 2020;41:111\u201388.","journal-title":"Eur Heart J"},{"key":"568_CR11","unstructured":"Website. Available: Documenti on line STRIDE BP (2021) Validated devices for home blood pressure monitoring. https:\/\/stridebp.org\/bp-monitors\/37-pdfs\/734-home?format=pdf&tmpl=component&-box=home."},{"key":"568_CR12","doi-asserted-by":"publisher","DOI":"10.1201\/9781420010718","volume-title":"Statistical computing with R","author":"ML Rizzo","year":"2007","unstructured":"Rizzo ML. Statistical computing with R. Philadelphia: Chapman & Hall\/CRC; 2007. https:\/\/doi.org\/10.1201\/9781420010718."},{"key":"568_CR13","doi-asserted-by":"publisher","first-page":"1952","DOI":"10.2174\/1381612826666201207230956","volume":"27","author":"R Del Pinto","year":"2021","unstructured":"Del Pinto R, Dobre M, Pagliacci S, Ferri C. Impact of guidelines on hypertension control in the elderly. Curr Pharm Des. 2021;27:1952\u20139.","journal-title":"Curr Pharm Des"},{"key":"568_CR14","doi-asserted-by":"publisher","first-page":"1228","DOI":"10.1177\/2047487319851301","volume":"27","author":"R Del Pinto","year":"2020","unstructured":"Del Pinto R, Pagliacci S, De Feo M, Grassi D, Ferri C, Italian Society of Hypertension and Federfarma. Prevalence of hypertension and associated cardiovascular risk factors among pharmacies customers: an Italian nationwide epidemiological survey. Eur J Prev Cardiol. 2020;27:1228\u201330.","journal-title":"Eur J Prev Cardiol"},{"key":"568_CR15","doi-asserted-by":"publisher","first-page":"1797","DOI":"10.1016\/j.jacc.2018.02.033","volume":"71","author":"NK Wenger","year":"2018","unstructured":"Wenger NK, Arnold A, Bairey Merz CN, Cooper-DeHoff RM, Ferdinand KC, Fleg JL, et al. Hypertension across a woman\u2019s life cycle. J Am Coll Cardiol. 2018;71:1797\u2013813.","journal-title":"J Am Coll Cardiol"},{"issue":"10\u20133","key":"568_CR16","first-page":"20","volume":"4","author":"D Martins","year":"2001","unstructured":"Martins D, Nelson K, Pan D, Tareen N, Norris K. The effect of gender on age-related blood pressure changes and the prevalence of isolated systolic hypertension among older adults: data from NHANES III. J Gend Specif Med. 2001;4(10\u20133):20.","journal-title":"J Gend Specif Med"},{"key":"568_CR17","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1161\/HYPERTENSIONAHA.107.105742","volume":"51","author":"M Coylewright","year":"2008","unstructured":"Coylewright M, Reckelhoff JF, Ouyang P. Menopause and hypertension: an age-old debate. Hypertension. 2008;51:952\u20139.","journal-title":"Hypertension"},{"key":"568_CR18","doi-asserted-by":"publisher","first-page":"e146","DOI":"10.1161\/CIR.0000000000000485","volume":"135","author":"EJ Benjamin","year":"2017","unstructured":"Benjamin EJ, Blaha MJ, Chiuve SE, Cushman M, Das SR, Deo R, et al. Heart disease and stroke statistics-2017 update: a report from the American Heart Association. Circulation. 2017;135:e146\u2013603.","journal-title":"Circulation"},{"key":"568_CR19","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1161\/HYPERTENSIONAHA.107.107342","volume":"51","author":"S Keyhani","year":"2008","unstructured":"Keyhani S, Scobie JV, Hebert PL, McLaughlin MA. Gender disparities in blood pressure control and cardiovascular care in a national sample of ambulatory care visits. Hypertension. 2008;51:1149\u201355.","journal-title":"Hypertension"},{"key":"568_CR20","doi-asserted-by":"publisher","first-page":"2455","DOI":"10.1093\/eurheartj\/ehab312","volume":"42","author":"SCORE2-OP Working Group and ESC Cardiovascular Risk Collaboration","year":"2021","unstructured":"SCORE2-OP Working Group and ESC Cardiovascular Risk Collaboration. SCORE2-OP risk prediction algorithms: estimating incident cardiovascular event risk in older persons in four geographical risk regions. Eur Heart J. 2021;42:2455\u201367.","journal-title":"Eur Heart J"}],"updated-by":[{"DOI":"10.1007\/s40292-023-00599-w","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T00:00:00Z","timestamp":1694563200000}}],"container-title":["High Blood Pressure &amp; Cardiovascular Prevention"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40292-023-00568-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40292-023-00568-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40292-023-00568-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T10:18:14Z","timestamp":1694600294000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40292-023-00568-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,11]]},"references-count":20,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,3]]}},"alternative-id":["568"],"URL":"https:\/\/doi.org\/10.1007\/s40292-023-00568-3","relation":{"correction":[{"id-type":"doi","id":"10.1007\/s40292-023-00599-w","asserted-by":"object"}]},"ISSN":["1179-1985"],"issn-type":[{"value":"1179-1985","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,11]]},"assertion":[{"value":"19 December 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 February 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 March 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 September 2023","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s40292-023-00599-w","URL":"https:\/\/doi.org\/10.1007\/s40292-023-00599-w","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This work and the Open Access publication fees were funded by Servier Italia.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"The authors Rita Del Pinto, Corrado Giua, Enrico Keber and Claudio Ferri declare that they have no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"CF was responsible for conceptualization, data analysis and interpretation; TM and CF performed the SCORE2 risk assessment; RDP wrote the first draft and edited the manuscript; GE, TM, CG, EK and CF edited the manuscript. All authors read and approved the manuscript.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Author contributions"}}]}}