{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:18:11Z","timestamp":1790115491835,"version":"4.0.1"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"name":"Universit\u00e0 degli Studi di Roma La Sapienza"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["High Blood Press Cardiovasc Prev"],"DOI":"10.1007\/s40292-025-00772-3","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T07:21:35Z","timestamp":1767770495000},"page":"239-248","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical Use of the Triglycerides\/Glucose (TyG) Index in the Early Assessment of Metabolic Alterations and Cardiovascular Remodeling in Essential Hypertensive Patients"],"prefix":"10.1007","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4463-4956","authenticated-orcid":false,"given":"Luigi","family":"Petramala","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gioacchino","family":"Galardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Marino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Circosta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Nardoianni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Baratta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Caprioni Grasso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Moscucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuliano","family":"Tocci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovambattista","family":"Desideri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Letizia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,7]]},"reference":[{"key":"772_CR1","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.numecd.2014.09.004","volume":"25","author":"X Song","year":"2015","unstructured":"Song X, Jousilahti P, Stehouwer CDA, et al. Cardiovascular and all-cause mortality in relation to various anthropometric measures of obesity in Europeans. Nutr Metab Cardiovasc Dis. 2015;25:295\u2013304.","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"772_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2025.104102","author":"L Lind","year":"2025","unstructured":"Lind L, Ris\u00e9rus U, Elmst\u00e5hl S, \u00c4rnl\u00f6v J, Micha\u00eblsson K, Titova OE. Combinations of BMI and metabolic syndrome and the risk of myocardial infarction, stroke, and heart failure. Nutr Metab Cardiovasc Dis. 2025. https:\/\/doi.org\/10.1016\/j.numecd.2025.104102.","journal-title":"Nutr Metab Cardiovasc Dis"},{"issue":"6","key":"772_CR3","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1007\/s40292-020-00408-8","volume":"27","author":"C Mancusi","year":"2020","unstructured":"Mancusi C, Izzo R, di Gioia G, Losi MA, Barbato E, Morisco C. Insulin resistance the hinge between hypertension and type 2 diabetes. High Blood Press Cardiovasc Prev. 2020;27(6):515\u201326. https:\/\/doi.org\/10.1007\/s40292-020-00408-8.","journal-title":"High Blood Press Cardiovasc Prev"},{"key":"772_CR4","doi-asserted-by":"publisher","first-page":"773","DOI":"10.2337\/db09-9028","volume":"58","author":"RA Defronzo","year":"2009","unstructured":"Defronzo RA. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. Diabetes. 2009;58:773\u201395.","journal-title":"Diabetes"},{"key":"772_CR5","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00645.2007","author":"R Muniyappa","year":"2008","unstructured":"Muniyappa R, Lee S, Chen H, Quon MJ. Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. Am J Physiol Endocrinol Metab. 2008. https:\/\/doi.org\/10.1152\/ajpendo.00645.2007.","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"772_CR6","doi-asserted-by":"publisher","first-page":"3347","DOI":"10.1210\/jc.2010-0288","volume":"95","author":"F Guerrero-Romero","year":"2010","unstructured":"Guerrero-Romero F, Simental-Mend\u00eda LE, Gonz\u00e1lez-Ortiz M, Mart\u00ednez-Abundis E, Ramos-Zavala MG, Hern\u00e1ndez-Gonz\u00e1lez SO, et al. The product of triglycerides and glucose, a simple measure of insulin sensitivity. Comparison with the euglycemic-hyperinsulinemic clamp. J Clin Endocrinol Metab. 2010;95:3347\u201351.","journal-title":"J Clin Endocrinol Metab"},{"key":"772_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.nut.2021.111140","volume":"89","author":"A da Silva","year":"2021","unstructured":"da Silva A, Caldas APS, Pinto SL, Hermsdorff HHM, Marcadenti A, Bersch-Ferreira \u00c2C, et al. Dietary total antioxidant capacity is inversely associated with cardiovascular events and cardiometabolic risk factors: a cross-sectional study. Nutrition. 2021;89:1\u20137.","journal-title":"Nutrition"},{"key":"772_CR8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fcvm.2024.1369090","volume":"11","author":"L Petramala","year":"2024","unstructured":"Petramala L, Gigante A, Sarlo F, Servello A, Circosta F, Marino L, et al. Relevance of obesity-related organ damage and metabolic syndrome classification in cardiovascular and renal risk stratification in patients with essential hypertension. Front Cardiovasc Med. 2024;11:1\u201311.","journal-title":"Front Cardiovasc Med"},{"key":"772_CR9","doi-asserted-by":"publisher","first-page":"1874","DOI":"10.1097\/HJH.0000000000003480","volume":"41","author":"G Mancia","year":"2023","unstructured":"Mancia G, Kreutz R, Brunstr\u00f6m M, et al. 2023 ESH guidelines for the management of arterial hypertension the Task Force for the management of arterial hypertension of the European Society of Hypertension. J Hypertens. 2023;41:1874\u20132071.","journal-title":"J Hypertens"},{"key":"772_CR10","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.1093\/ehjci\/jew082","volume":"17","author":"SF Nagueh","year":"2016","unstructured":"Nagueh SF, Smiseth OA, Appleton CP, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Hear J Cardiovasc Imaging. 2016;17:1321\u201360.","journal-title":"Eur Hear J Cardiovasc Imaging"},{"key":"772_CR11","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1016\/S0140-6736(14)60460-8","volume":"384","author":"M Ng","year":"2014","unstructured":"Ng M, Fleming T, Robinson M, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980\u20132013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014;384:766\u201381.","journal-title":"Lancet"},{"key":"772_CR12","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.mayocp.2016.11.001","volume":"92","author":"S Carbone","year":"2017","unstructured":"Carbone S, Lavie CJ, Arena R. Obesity and heart failure: focus on the obesity paradox. Mayo Clin Proc. 2017;92:266\u201379.","journal-title":"Mayo Clin Proc"},{"key":"772_CR13","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1038\/s41569-018-0097-6","volume":"16","author":"EK Oikonomou","year":"2019","unstructured":"Oikonomou EK, Antoniades C. The role of adipose tissue in cardiovascular health and disease. Nat Rev Cardiol. 2019;16:83\u201399.","journal-title":"Nat Rev Cardiol"},{"key":"772_CR14","doi-asserted-by":"publisher","first-page":"E101","DOI":"10.1210\/jc.2014-2274","volume":"100","author":"C Letizia","year":"2015","unstructured":"Letizia C, Petramala L, Di Gioia CRT, Chiappetta C, Zinnamosca L, Marinelli C, et al. Leptin and adiponectin mRNA expression from the adipose tissue surrounding the adrenal neoplasia. J Clin Endocrinol Metab. 2015;100:E101\u20134.","journal-title":"J Clin Endocrinol Metab"},{"issue":"3","key":"772_CR15","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1007\/s40292-016-0137-4","volume":"23","author":"G Seravalle","year":"2016","unstructured":"Seravalle G, Grassi G. Sympathetic nervous system, hypertension, obesity and metabolic syndrome. High Blood Press Cardiovasc Prev. 2016;23(3):175\u20139. https:\/\/doi.org\/10.1007\/s40292-016-0137-4.","journal-title":"High Blood Press Cardiovasc Prev"},{"key":"772_CR16","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1016\/j.jacc.2016.11.069","volume":"69","author":"S Javaheri","year":"2017","unstructured":"Javaheri S, Barbe F, Campos-Rodriguez F, et al. Sleep apnea: types, mechanisms, and clinical cardiovascular consequences. J Am Coll Cardiol. 2017;69:841\u201358.","journal-title":"J Am Coll Cardiol"},{"key":"772_CR17","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1007\/s13679-020-00403-z","volume":"9","author":"A Elagizi","year":"2020","unstructured":"Elagizi A, Kachur S, Carbone S, Lavie CJ, Blair SN. A review of obesity, physical activity, and cardiovascular disease. Curr Obes Rep. 2020;9:571\u201381.","journal-title":"Curr Obes Rep"},{"key":"772_CR18","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.numecd.2018.10.003","volume":"29","author":"L D\u2019Elia","year":"2019","unstructured":"D\u2019Elia L, Strazzullo P, Iacone R, Russo O, Galletti F. Leptin levels predict the development of insulin resistance in a sample of adult men\u2013the Olivetti heart study. Nutr Metab Cardiovasc Dis. 2019;29:39\u201344.","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"772_CR19","doi-asserted-by":"publisher","first-page":"2363","DOI":"10.1097\/00004872-200412000-00019","volume":"22","author":"G Grassi","year":"2004","unstructured":"Grassi G, Dell\u2019Oro R, Facchini A, Trevano FQ, Bolla GB, Mancia G. Effect of central and peripheral body fat distribution on sympathetic and baroreflex function in obese normotensives. J Hypertens. 2004;22:2363\u20139.","journal-title":"J Hypertens"},{"key":"772_CR20","doi-asserted-by":"publisher","first-page":"2982","DOI":"10.1016\/j.jacc.2020.11.010","volume":"76","author":"GA Roth","year":"2020","unstructured":"Roth GA, Mensah GA, Johnson CO, et al. Global burden of cardiovascular diseases and risk factors, 1990-2019: update from the GBD 2019 study. J Am Coll Cardiol. 2020;76:2982\u20133021.","journal-title":"J Am Coll Cardiol"},{"key":"772_CR21","doi-asserted-by":"publisher","first-page":"2","DOI":"10.2174\/1573399810666140214093600","volume":"10","author":"E Cersosimo","year":"2014","unstructured":"Cersosimo E, Solis-Herrera C, Trautmann ME, Malloy J, Triplitt CL. Send orders for reprints to reprints@benthamscience.net assessment of pancreatic-cell function: review of methods and clinical applications. Curr Diabetes Rev. 2014;10:2\u201342.","journal-title":"Curr Diabetes Rev"},{"key":"772_CR22","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1089\/met.2008.0034","volume":"6","author":"LE Simental-Mend\u00eda","year":"2008","unstructured":"Simental-Mend\u00eda LE, Rodr\u00edguez-Mor\u00e1n M, Guerrero-Romero F. The product of fasting glucose and triglycerides as surrogate for identifying insulin resistance in apparently healthy subjects. Metab Syndr Relat Disord. 2008;6:299\u2013304.","journal-title":"Metab Syndr Relat Disord"},{"key":"772_CR23","doi-asserted-by":"publisher","first-page":"25F","DOI":"10.1016\/S0002-9149(99)00211-8","volume":"83","author":"SM Grundy","year":"1999","unstructured":"Grundy SM. Hypertriglyceridemia, insulin resistance, and the metabolic syndrome. Am J Cardiol. 1999;83:25F-29F.","journal-title":"Am J Cardiol"},{"key":"772_CR24","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2024.07.010","volume":"34","author":"R Ram\u00edrez-V\u00e9lez","year":"2024","unstructured":"Ram\u00edrez-V\u00e9lez R, Izquierdo M, Garc\u00eda-Hermoso A, Correa-Rodr\u00edguez M. Corrigendum to \u201cReference values and associated factors of controlled attenuation parameter and liver stiffness in adults: a cross-sectional study\u201d [Nutr Metabol Cardiovasc Dis 34 (8) (2024) 1879-1889]. Nutr Metab Cardiovasc Dis. 2024;34:2610.","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"772_CR25","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1016\/j.numecd.2023.03.026","volume":"33","author":"X Ren","year":"2023","unstructured":"Ren X, Jiang M, Han L, Zheng X. Association between triglyceride-glucose index and chronic kidney disease: a cohort study and meta-analysis. Nutr Metab Cardiovasc Dis. 2023;33:1121\u20138.","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"772_CR26","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1186\/s13098-023-01117-7","volume":"15","author":"Y Yu","year":"2023","unstructured":"Yu Y, Wang J, Ding L, et al. Sex differences in the nonlinear association of triglyceride glucose index with all-cause and cardiovascular mortality in the general population. Diabetol Metab Syndr. 2023;15:136.","journal-title":"Diabetol Metab Syndr"},{"key":"772_CR27","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1016\/j.numecd.2021.11.017","volume":"32","author":"D-H Son","year":"2022","unstructured":"Son D-H, Lee HS, Lee Y-J, Lee J-H, Han J-H. Comparison of triglyceride-glucose index and HOMA-IR for predicting prevalence and incidence of metabolic syndrome. Nutr Metab Cardiovasc Dis. 2022;32:596\u2013604.","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"772_CR28","doi-asserted-by":"publisher","DOI":"10.1080\/10641963.2024.2341631","volume":"46","author":"C Yang","year":"2024","unstructured":"Yang C, Song Y, Wang P. Relationship between triglyceride-glucose index and new-onset hypertension in general population-a systemic review and meta-analysis of cohort studies. Clin Exp Hypertens. 2024;46:2341631.","journal-title":"Clin Exp Hypertens"},{"key":"772_CR29","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1016\/j.numecd.2023.02.014","volume":"33","author":"J Zhang","year":"2023","unstructured":"Zhang J, Wang R, Liu Q, Song G, Tang X. Association of triglyceride-glucose index with incident hypertension among non-overweight healthy adults: a cohort study in China. Nutr Metab Cardiovasc Dis. 2023;33:1057\u201365.","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"772_CR30","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.901180","volume":"9","author":"Q Cai","year":"2022","unstructured":"Cai Q, Xing CY, Zhu J, Wang Y, Lu F, Peng J. Associations between triglyceride-glucose index and different hypertension subtypes: a population-based study in China. Front Cardiovasc Med. 2022;9:901180.","journal-title":"Front Cardiovasc Med"},{"key":"772_CR31","doi-asserted-by":"publisher","DOI":"10.1080\/10641963.2023.2272581","volume":"45","author":"J Pang","year":"2023","unstructured":"Pang J, Qian L, Che X, Lv P, Xu Q. TyG index is a predictor of all-cause mortality during the long-term follow-up in middle-aged and elderly with hypertension. Clin Exp Hypertens. 2023;45:2272581.","journal-title":"Clin Exp Hypertens"},{"key":"772_CR32","doi-asserted-by":"publisher","DOI":"10.1007\/s40292-025-00741-w","author":"I Garofani","year":"2025","unstructured":"Garofani I, Tognola C, Morelli M, Shkodra A, Algeri M, Bellomare M, et al. Pulse wave velocity progression determinants: no significant association with novel lipids parameter. High Blood Press Cardiovasc Prev. 2025. https:\/\/doi.org\/10.1007\/s40292-025-00741-w.","journal-title":"High Blood Press Cardiovasc Prev"},{"key":"772_CR33","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.114151","volume":"158","author":"W-Z Wu","year":"2023","unstructured":"Wu W-Z, Bai Y-P. Endothelial GLUTs and vascular biology. Biomed Pharmacother. 2023;158:114151.","journal-title":"Biomed Pharmacother"},{"key":"772_CR34","doi-asserted-by":"publisher","first-page":"1640","DOI":"10.1161\/CIRCULATIONAHA.109.192644","volume":"120","author":"KGMM Alberti","year":"2009","unstructured":"Alberti KGMM, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009;120:1640\u20135.","journal-title":"Circulation"},{"issue":"6","key":"772_CR35","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1007\/s40292-022-00542-5","volume":"29","author":"JG Gonz\u00e1lez-Gonz\u00e1lez","year":"2022","unstructured":"Gonz\u00e1lez-Gonz\u00e1lez JG, Violante-Cumpa JR, Zambrano-Lucio M, Burciaga-Jimenez E, Castillo-Morales PL, Garcia-Campa M, et al. HOMA-IR as a predictor of Health Outcomes in Patients with Metabolic Risk Factors: a systematic review and meta-analysis. High Blood Press Cardiovasc Prev. 2022;29(6):547\u201364. https:\/\/doi.org\/10.1007\/s40292-022-00542-5.","journal-title":"High Blood Press Cardiovasc Prev"},{"key":"772_CR36","doi-asserted-by":"publisher","first-page":"2677","DOI":"10.1016\/j.numecd.2022.07.024","volume":"32","author":"SA Nabipoorashrafi","year":"2022","unstructured":"Nabipoorashrafi SA, Seyedi SA, Rabizadeh S, Ebrahimi M, Ranjbar SA, Reyhan SK, et al. The accuracy of triglyceride-glucose (TyG) index for the screening of metabolic syndrome in adults: a systematic review and meta-analysis. Nutr Metab Cardiovasc Dis. 2022;32:2677\u201388.","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"772_CR37","first-page":"1","volume":"95","author":"D Navarro-Gonz\u00e1lez","year":"2016","unstructured":"Navarro-Gonz\u00e1lez D, S\u00e1nchez-\u00cdn\u0129go L, Fern\u00e1ndez-Montero A, Pastrana-Delgado J, Alfredo Martinez J. TyG index change is more determinant for forecasting type 2 diabetes onset than weight gain. Med (United States). 2016;95:1\u20139.","journal-title":"Med (United States)"},{"key":"772_CR38","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmedr.2022.101941","volume":"29","author":"SP Ara\u00fajo","year":"2022","unstructured":"Ara\u00fajo SP, Juvanhol LL, Bressan J, Hermsdorff HHM. Triglyceride glucose index: a new biomarker in predicting cardiovascular risk. Prev Med Rep. 2022;29:101941.","journal-title":"Prev Med Rep"},{"key":"772_CR39","first-page":"1","volume":"8","author":"S Yang","year":"2021","unstructured":"Yang S, Du Y, Liu Z, Zhang R, Lin X, Ouyang Y, et al. Triglyceride-glucose index and extracellular volume fraction in patients with heart failure. Front Cardiovasc Med. 2021;8:1\u20138.","journal-title":"Front Cardiovasc Med"},{"key":"772_CR40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.cpcardiol.2022.101156","volume":"47","author":"A Avagimyan","year":"2022","unstructured":"Avagimyan A, Popov S, Shalnova S. The pathophysiological basis of diabetic cardiomyopathy development. Curr Probl Cardiol. 2022;47:1\u201312.","journal-title":"Curr Probl Cardiol"},{"key":"772_CR41","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpcardiol.2023.101923","volume":"48","author":"S Suman","year":"2023","unstructured":"Suman S, Biswas A, Kohaf N, Singh C, Johns R, Jakkula P, et al. The diabetes-heart disease connection: recent discoveries and implications. Curr Probl Cardiol. 2023;48:101923.","journal-title":"Curr Probl Cardiol"},{"key":"772_CR42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.cpcardiol.2023.102052","volume":"49","author":"A Avagimyan","year":"2024","unstructured":"Avagimyan A, Fogacci F, Pogosova N, et al. Diabetic Cardiomyopathy: 2023 Update by the International Multidisciplinary Board of Experts. Curr Probl Cardiol. 2024;49:1\u201320.","journal-title":"Curr Probl Cardiol"},{"key":"772_CR43","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1002\/ehf2.14224","volume":"10","author":"J Ke","year":"2023","unstructured":"Ke J, Pan J, Lin H, Gu J. Diabetic cardiomyopathy: a brief summary on lipid toxicity. ESC Hear Fail. 2023;10:776\u201390.","journal-title":"ESC Hear Fail"},{"key":"772_CR44","doi-asserted-by":"publisher","first-page":"2022","DOI":"10.1097\/HJH.0000000000000284","volume":"32","author":"L Petramala","year":"2014","unstructured":"Petramala L, Pignatelli P, Carnevale R, et al. Oxidative stress in patients affected by primary aldosteronism. J Hypertens. 2014;32:2022\u20139.","journal-title":"J Hypertens"},{"key":"772_CR45","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.cpcardiol.2017.05.001","volume":"43","author":"AA Oktay","year":"2018","unstructured":"Oktay AA, Akturk HK, Esenbo\u011fa K, Javed F, Polin NM, Jahangir E. Pathophysiology and prevention of heart disease in diabetes mellitus. Curr Probl Cardiol. 2018;43:68\u2013110.","journal-title":"Curr Probl Cardiol"},{"key":"772_CR46","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12933-023-01973-7","volume":"22","author":"A Khalaji","year":"2023","unstructured":"Khalaji A, Behnoush AH, Khanmohammadi S, Ghanbari Mardasi K, Sharifkashani S, Sahebkar A, et al. Triglyceride-glucose index and heart failure: a systematic review and meta-analysis. Cardiovasc Diabetol. 2023;22:1\u201316.","journal-title":"Cardiovasc Diabetol"},{"key":"772_CR47","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2025.1597112","author":"K Song","year":"2025","unstructured":"Song K, Xu Y, Wu S, Zhang X, Wang Y, Pan S. Research status of triglyceride glucose-body mass index (TyG-BMI index). Front Cardiovasc Med. 2025. https:\/\/doi.org\/10.3389\/fcvm.2025.1597112.","journal-title":"Front Cardiovasc Med"},{"key":"772_CR48","doi-asserted-by":"publisher","DOI":"10.1007\/s40292-025-00749-2","author":"Q Yan","year":"2025","unstructured":"Yan Q, Cai W, Wu J, Guo Y. Associations of the triglyceride-glucose index and body fat composition with blood pressure in children and adolescents. High Blood Press Cardiovasc Prev. 2025. https:\/\/doi.org\/10.1007\/s40292-025-00749-2.","journal-title":"High Blood Press Cardiovasc Prev"}],"container-title":["High Blood Pressure & Cardiovascular Prevention"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40292-025-00772-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40292-025-00772-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40292-025-00772-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T23:26:38Z","timestamp":1773530798000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40292-025-00772-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,7]]},"references-count":48,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,3]]}},"alternative-id":["772"],"URL":"https:\/\/doi.org\/10.1007\/s40292-025-00772-3","relation":{},"ISSN":["1179-1985"],"issn-type":[{"value":"1179-1985","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,7]]},"assertion":[{"value":"23 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"the authors have no conflict of interest to disclose for the contents of the present manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was approved by the Local Committee of the Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences (date of approval: 19 December 2023).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}