{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T21:00:03Z","timestamp":1785099603803,"version":"3.55.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2021,11,20]],"date-time":"2021-11-20T00:00:00Z","timestamp":1637366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,11,20]],"date-time":"2021-11-20T00:00:00Z","timestamp":1637366400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Paediatr Dent"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>Osteogenesis imperfecta (OI) results from mutations in the genes involved in the modification or biosynthesis of collagen. This study aimed to assess the oral health-related quality of life (OHRQoL) in children with OI.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methodology<\/jats:title>\n                <jats:p>Participants were recruited from a highly specialised OI centre for children. The Child Oral-Health Impact Profile\u2014Short Form (COHIP-SF) was used, adding demographic and qualitative questions. Children aged 8\u201316\u00a0years participated between January and October 2019. Statistical analysis was carried out. A higher COHIP-SF score indicates better OHRQoL (maximum score, 76).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>One hundred and six (106) children participated (44 female, mean age 11.93\u00a0years). COHIP-SF median score was 59. Children reporting mild OI (<jats:italic>n<\/jats:italic>\u2009=\u200955) had higher median scores (62) compared to severe OI (<jats:italic>n<\/jats:italic>\u2009=\u20097) with median scores of 55 (<jats:italic>P<\/jats:italic>\u2009=\u20090.087). When comparing mixed (&lt;\u200912\u00a0years, <jats:italic>n<\/jats:italic>\u2009=\u200946) and permanent dentition (\u2265\u200912, <jats:italic>n<\/jats:italic>\u2009=\u200960), no significant difference in OHRQoL was seen (<jats:italic>P<\/jats:italic>\u2009=\u20090.977). There was no significant difference between severities for each COHIP-SF domain. Limited data on the presence of dentinogenesis imperfecta did not impact overall score (<jats:italic>P<\/jats:italic>\u2009=\u20090.109), but was significant in the oral-health domain (<jats:italic>P<\/jats:italic>\u2009=\u20090.033).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Qualitative<\/jats:title>\n                <jats:p>Common themes were the need for braces, discolouration, pain and function.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This study confirmed that children with OI have dental concerns in areas including oral health, functional well-being and socio-emotional well-being. This was related to severity of OI.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s40368-021-00664-9","type":"journal-article","created":{"date-parts":[[2021,11,20]],"date-time":"2021-11-20T04:35:00Z","timestamp":1637382900000},"page":"261-270","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Oral health-related quality of life in children with osteogenesis imperfecta"],"prefix":"10.1007","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9946-4849","authenticated-orcid":false,"given":"J. 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The authors have no conflicts of interest to declare that are relevant to the content of this article. All authors certify that they have no affiliations with or involvement in any organisation or entity with any financial interest or non-financial interest in the subject matter or materials discussed in this manuscript. The authors have no financial or proprietary interests in any material discussed in this article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Financial interests"}},{"value":"Ethical approval was obtained from the North of Scotland Research Ethics Committee (reference number: 18\/NS\/0129) on the 14th November 2018.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was obtained from the parents.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}