{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:05:31Z","timestamp":1790114731449,"version":"4.0.1"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T00:00:00Z","timestamp":1759449600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T00:00:00Z","timestamp":1759449600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Paediatr Dent"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>The European Academy of Paediatric Dentistry (EAPD) has developed this best clinical practice guidance on the use of antibiotics in pediatric dentistry, aiming to address challenges posed by antimicrobial resistance (AMR) and promote the responsible use of antibiotics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A comprehensive review of existing literature and global policies was conducted to evaluate antibiotic-prescribing practices for children. Recommendations were developed through a consensus process involving experts in pediatric dentistry during the EAPD policy workshop in Prague in May 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The guidelines highlight the critical role of prudent antibiotic use to mitigate the growing threat of AMR. Specific recommendations include no routine antibiotic use for localized pulpitis or abscess without systemic involvement and targeted use for odontogenic infections with systemic signs. Detailed dosage protocols are provided, accounting for age, weight, and clinical context. Prophylaxis is recommended only for high-risk patients undergoing specific invasive procedures. Significant variations in national practices were noted, underlining the need for harmonized evidence-based protocols.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These guidelines serve as a framework to optimize antibiotic use in children, emphasizing the importance of targeted prescribing practices and the implementation of preventive strategies in pediatric dental care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s40368-025-01068-9","type":"journal-article","created":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T11:58:07Z","timestamp":1759492687000},"page":"1037-1043","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Best clinical practise guidance for the use of antibiotics in children: an EAPD policy document"],"prefix":"10.1007","volume":"26","author":[{"given":"S.","family":"Rajasekharan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Lygidakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Cauwels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Declerck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Monteiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Parekh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,10,3]]},"reference":[{"key":"1068_CR1","unstructured":"Alaluusua S, Veerkamp J and Declerck D. 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