{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T02:50:25Z","timestamp":1782787825521,"version":"3.54.5"},"reference-count":55,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2025,8,24]],"date-time":"2025-08-24T00:00:00Z","timestamp":1755993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,8,24]],"date-time":"2025-08-24T00:00:00Z","timestamp":1755993600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Paediatr Dent"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1007\/s40368-025-01100-y","type":"journal-article","created":{"date-parts":[[2025,8,24]],"date-time":"2025-08-24T19:28:25Z","timestamp":1756063705000},"page":"1057-1075","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Evidence mapping and quality assessment of randomised trials related to molar incisor hypomineralisation"],"prefix":"10.1007","volume":"26","author":[{"given":"J.","family":"Garima","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Wadhwani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Tewari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Bekes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Mathur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Rahul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,8,24]]},"reference":[{"key":"1100_CR1","doi-asserted-by":"publisher","DOI":"10.1007\/s40368-022-00722-w","author":"OB Al-Batayneh","year":"2022","unstructured":"Al-Batayneh OB, Abdelghani IM. Outcome of vital pulp therapy in deeply carious molars affected with molar incisor hypomineralisation (MIH) defects: a randomized clinical trial. Eur Arch Paediatr Dent. 2022. https:\/\/doi.org\/10.1007\/s40368-022-00722-w.","journal-title":"Eur Arch Paediatr Dent"},{"key":"1100_CR2","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.136653.2","author":"Z Al-Nerabieah","year":"2024","unstructured":"Al-Nerabieah Z, AlKhouli M, Dashash M. Preventive efficacy of 38% silver diamine fluoride and CPP-ACP fluoride varnish on molars affected by molar incisor hypomineralization in children: a randomized controlled trial. F1000Res. 2024. https:\/\/doi.org\/10.12688\/f1000research.136653.2.","journal-title":"F1000Res"},{"key":"1100_CR3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2022.104168","author":"GDS Athayde","year":"2022","unstructured":"Athayde GDS, Reis PPGD, Jorge RC, et al. Impact of masking hypomineralization opacities in anterior teeth on the esthetic perception of children and parents: a randomized controlled clinical trial. J Dent. 2022. https:\/\/doi.org\/10.1016\/j.jdent.2022.104168.","journal-title":"J Dent"},{"key":"1100_CR4","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.13118","author":"B Aykanat","year":"2024","unstructured":"Aykanat B, Elbay M. Effect of photobiomodulation on the efficacy of anesthesia in maxillary permanent molar teeth with molar incisor hypomineralization: a randomized clinical trial. Int J Paediatr Dent. 2024. https:\/\/doi.org\/10.1111\/ipd.13118.","journal-title":"Int J Paediatr Dent"},{"key":"1100_CR5","doi-asserted-by":"publisher","DOI":"10.3390\/dj12060186","author":"E Bardellini","year":"2024","unstructured":"Bardellini E, Amadori F, Rosselli L, et al. Molar incisor hypomineralization: optimizing treatment protocols for hypersensitivity: a randomized clinical trial. Dent J (Basel). 2024. https:\/\/doi.org\/10.3390\/dj12060186.","journal-title":"Dent J (Basel)"},{"key":"1100_CR6","doi-asserted-by":"publisher","DOI":"10.1007\/s40368-023-00848-5","author":"K Bekes","year":"2023","unstructured":"Bekes K, Kr\u00e4mer N, Steffen R. Update of the molar incisor hypomineralization: W\u00fcrzburg concept. Eur Arch Paediatr Dent. 2023. https:\/\/doi.org\/10.1007\/s40368-023-00848-5.","journal-title":"Eur Arch Paediatr Dent"},{"key":"1100_CR7","doi-asserted-by":"publisher","DOI":"10.4103\/ccd.ccd_852_17","author":"R Bhandari","year":"2019","unstructured":"Bhandari R, Thakur S, Singhal P, Chauhan D, et al. In vivo comparative evaluation of esthetics after microabrasion and microabrasion followed by casein phosphopeptide-amorphous calcium fluoride phosphate on molar incisor hypomineralization-affected incisors. Contemp Clin Dent. 2019. https:\/\/doi.org\/10.4103\/ccd.ccd_852_17.","journal-title":"Contemp Clin Dent"},{"key":"1100_CR8","doi-asserted-by":"publisher","DOI":"10.1111\/odi.14388","author":"A Butera","year":"2023","unstructured":"Butera A, Pascadopoli M, Pellegrini M, et al. Biomimetic hydroxyapatite paste for molar-incisor hypomineralization: a randomized clinical trial. Oral Dis. 2023. https:\/\/doi.org\/10.1111\/odi.14388.","journal-title":"Oral Dis"},{"key":"1100_CR9","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-019-3944-9","author":"F Catal\u00e1-L\u00f3pez","year":"2020","unstructured":"Catal\u00e1-L\u00f3pez F, Aleixandre-Benavent R, Caulley L, et al. Global mapping of randomised trials related articles published in high-impact-factor medical journals: a cross-sectional analysis. Trials. 2020. https:\/\/doi.org\/10.1186\/s13063-019-3944-9.","journal-title":"Trials"},{"key":"1100_CR10","doi-asserted-by":"publisher","DOI":"10.1007\/s40368-021-00676-5","author":"RT da Costa","year":"2022","unstructured":"da Costa RT, Pintor AV, Magno MB, et al. Worldwide trends on molar incisor and deciduous molar hypomineralisation research: a bibliometric analysis over a 19-year period. Eur Arch Paediatr Dent. 2022. https:\/\/doi.org\/10.1007\/s40368-021-00676-5.","journal-title":"Eur Arch Paediatr Dent"},{"key":"1100_CR11","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-016-1968-z","author":"JF de Souza","year":"2017","unstructured":"de Souza JF, Fragelli CB, Jeremias F, et al. Eighteen-month clinical performance of composite resin restorations with two different adhesive systems for molars affected by molar incisor hypomineralization. Clin Oral Investig. 2017. https:\/\/doi.org\/10.1007\/s00784-016-1968-z.","journal-title":"Clin Oral Investig"},{"key":"1100_CR12","doi-asserted-by":"publisher","DOI":"10.1007\/s40368-019-00430-y","author":"A Dhareula","year":"2019","unstructured":"Dhareula A, Goyal A, Gauba K, et al. A clinical and radiographic investigation comparing the efficacy of cast metal and indirect resin onlays in rehabilitation of permanent first molars affected with severe molar incisor hypomineralisation (MIH): a 36-month randomised controlled clinical trial. Eur Arch Paediatr Dent. 2019. https:\/\/doi.org\/10.1007\/s40368-019-00430-y.","journal-title":"Eur Arch Paediatr Dent"},{"key":"1100_CR13","doi-asserted-by":"publisher","DOI":"10.4103\/ccd.ccd_252_18","author":"UB Dixit","year":"2018","unstructured":"Dixit UB, Joshi AV. Efficacy of intraosseous local anesthesia for restorative procedures in molar incisor hypomineralization-affected teeth in children. Contemp Clin Dent. 2018. https:\/\/doi.org\/10.4103\/ccd.ccd_252_18.","journal-title":"Contemp Clin Dent"},{"key":"1100_CR14","doi-asserted-by":"publisher","DOI":"10.3290\/j.ohpd.b2403649","author":"V Ehlers","year":"2021","unstructured":"Ehlers V, Reuter AK, Kehl EB, et al. Efficacy of a toothpaste based on microcrystalline hydroxyapatite on children with hypersensitivity caused by MIH: a randomised controlled trial. Oral Health Prev Dent. 2021. https:\/\/doi.org\/10.3290\/j.ohpd.b2403649.","journal-title":"Oral Health Prev Dent"},{"key":"1100_CR15","doi-asserted-by":"publisher","DOI":"10.1016\/j.sdentj.2023.05.028","author":"AM Eldehna","year":"2023","unstructured":"Eldehna AM, Montaser AG, ALrafee SA, Abdelgawad A. Clinical outcome of CAD\/CAM overlays of MIH affected young permanent molars. Saudi Dent J. 2023. https:\/\/doi.org\/10.1016\/j.sdentj.2023.05.028.","journal-title":"Saudi Dent J"},{"key":"1100_CR16","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-023-03501-1","author":"N Geduk","year":"2023","unstructured":"Geduk N, Ozdemir M, Erbas Unverdi G, et al. Clinical and radiographic performance of preformed zirconia crowns and stainless-steel crowns in permanent first molars: 18-month results of a prospective, randomized trial. BMC Oral Health. 2023. https:\/\/doi.org\/10.1186\/s12903-023-03501-1.","journal-title":"BMC Oral Health"},{"key":"1100_CR17","doi-asserted-by":"publisher","DOI":"10.1007\/s40368-023-00827-w","author":"M Haidar","year":"2023","unstructured":"Haidar M, Raslan N. Comparative study of articaine 4% versus lidocaine 2% in the local anesthesia of permanent mandibular first molars affected by MIH: a randomized controlled trial. Eur Arch Paediatr Dent. 2023. https:\/\/doi.org\/10.1007\/s40368-023-00827-w.","journal-title":"Eur Arch Paediatr Dent"},{"key":"1100_CR18","doi-asserted-by":"publisher","DOI":"10.1038\/s41405-023-00165-5","author":"A Hakmi","year":"2023","unstructured":"Hakmi A, Dashash M. Direct or indirect composite for restoring permanent first molars affected by molar incisor hypomineralisation (MIH): a randomized clinical controlled trial. BDJ Open. 2023. https:\/\/doi.org\/10.1038\/s41405-023-00165-5.","journal-title":"BDJ Open"},{"key":"1100_CR19","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(25)00672-5","author":"S Hopewell","year":"2025","unstructured":"Hopewell S, Chan AW, Collins GS, Hr\u00f3bjartsson A, et al. CONSORT 2025 statement: updated guideline for reporting randomised trials. Lancet. 2025. https:\/\/doi.org\/10.1016\/S0140-6736(25)00672-5.","journal-title":"Lancet"},{"key":"1100_CR20","first-page":"292","volume":"45","author":"R Kaya","year":"2023","unstructured":"Kaya R, Yavuz B\u015eE, Dokumac\u0131gil NK, Karg\u00fcl B. A randomized clinical trial of short fiber reinforced composite and glass hybrid restoration for molars affected by molar hypomineralization. Pediatr Dent. 2023;45:292\u2013300.","journal-title":"Pediatr Dent"},{"key":"1100_CR21","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-01541-7","author":"LB Lopes","year":"2021","unstructured":"Lopes LB, Machado V, Mascarenhas P, et al. The prevalence of molar-incisor hypomineralization: a systematic review and meta-analysis. Sci Rep. 2021. https:\/\/doi.org\/10.1038\/s41598-021-01541-7.","journal-title":"Sci Rep"},{"key":"1100_CR22","doi-asserted-by":"publisher","DOI":"10.1007\/BF03262686","author":"NA Lygidakis","year":"2009","unstructured":"Lygidakis NA, Dimou G, Stamataki E. Retention of fissure sealants using two different methods of application in teeth with hypomineralised molars (MIH): a 4 year clinical study. Eur Arch Paediatr Dent. 2009. https:\/\/doi.org\/10.1007\/BF03262686.","journal-title":"Eur Arch Paediatr Dent"},{"key":"1100_CR23","doi-asserted-by":"publisher","DOI":"10.1007\/s40368-021-00668-5","author":"NA Lygidakis","year":"2022","unstructured":"Lygidakis NA, Garot E, Somani C, et al. Best clinical practice guidance for clinicians dealing with children presenting with molar-incisor-hypomineralisation (MIH): an updated European Academy of Paediatric Dentistry policy document. Eur Arch Paediatr Dent. 2022. https:\/\/doi.org\/10.1007\/s40368-021-00668-5.","journal-title":"Eur Arch Paediatr Dent"},{"key":"1100_CR24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2024.105554","author":"O Marouane","year":"2025","unstructured":"Marouane O, Manton DJ, Cebula M, et al. In vivo comparison of resin infiltration outcomes under different light conditions: a randomized controlled clinical trial. J Dent. 2025. https:\/\/doi.org\/10.1016\/j.jdent.2024.105554.","journal-title":"J Dent"},{"key":"1100_CR25","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2024.11.017","author":"NO Miranda","year":"2025","unstructured":"Miranda NO, Dos Anjos LM, Rocha AO, et al. Global research interest and publication trends on guided surgery in implant dentistry: a metrics-based analysis. J Prosthet Dent. 2025. https:\/\/doi.org\/10.1016\/j.prosdent.2024.11.017.","journal-title":"J Prosthet Dent"},{"key":"1100_CR26","doi-asserted-by":"publisher","DOI":"10.21608\/asdj.2022.78983.1049","author":"H Mohie","year":"2022","unstructured":"Mohie H, Radwan M, Abd El-Aziz A. A comparison of two different management techniques for extensive molar defects in patients suffering from Molar Incisor Hypomineralization (MIH)(A Randomized Clinical Trial). Ain Shams Dent J. 2022. https:\/\/doi.org\/10.21608\/asdj.2022.78983.1049.","journal-title":"Ain Shams Dent J"},{"key":"1100_CR27","doi-asserted-by":"publisher","DOI":"10.2174\/0118742106268968231101065907","author":"AG Montaser","year":"2023","unstructured":"Montaser AG, Hashem SN, Ali MA, et al. Clinical performance of two CAD\/CAM fabricated ceramic restorations with different designs for MIH rehabilitation: a randomized controlled trial. Open Dent J. 2023. https:\/\/doi.org\/10.2174\/0118742106268968231101065907.","journal-title":"Open Dent J"},{"key":"1100_CR28","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.12602","author":"RSC Muniz","year":"2020","unstructured":"Muniz RSC, Carvalho CN, Aranha ACC, et al. Efficacy of low-level laser therapy associated with fluoride therapy for the desensitisation of molar-incisor hypomineralisation: randomised clinical trial. Int J Paediatr Dent. 2020. https:\/\/doi.org\/10.1111\/ipd.12602.","journal-title":"Int J Paediatr Dent"},{"key":"1100_CR29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2020.103570","author":"VKC Nogueira","year":"2021","unstructured":"Nogueira VKC, Mendes Soares IP, Fragelli CMB, et al. Structural integrity of MIH-affected teeth after treatment with fluoride varnish or resin infiltration: an 18-month randomized clinical trial. J Dent. 2021. https:\/\/doi.org\/10.1016\/j.jdent.2020.103570.","journal-title":"J Dent"},{"key":"1100_CR30","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-021-04305-9","author":"IC Olgen","year":"2022","unstructured":"Olgen IC, Sonmez H, Bezgin T. Effects of different remineralization agents on MIH defects: a randomized clinical study. Clin Oral Investig. 2022. https:\/\/doi.org\/10.1007\/s00784-021-04305-9.","journal-title":"Clin Oral Investig"},{"key":"1100_CR31","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-022-02298-9","author":"B \u00d6zg\u00fcr","year":"2022","unstructured":"\u00d6zg\u00fcr B, Karg\u0131n ST, \u00d6lmez MS. Clinical evaluation of giomer- and resin-based fissure sealants on permanent molars affected by molar-incisor hypomineralization: a randomized clinical trial. BMC Oral Health. 2022. https:\/\/doi.org\/10.1186\/s12903-022-02298-9.","journal-title":"BMC Oral Health"},{"key":"1100_CR32","doi-asserted-by":"publisher","DOI":"10.22514\/jocpd.2024.061","author":"M Ozsoy","year":"2024","unstructured":"Ozsoy M, Erken Gungor O. Management of severity lesions of hypomineralized molars (MIH) with different treatment alternatives: 9-month results of a clinical trial. J Clin Pediatr Dent. 2024. https:\/\/doi.org\/10.22514\/jocpd.2024.061.","journal-title":"J Clin Pediatr Dent"},{"key":"1100_CR33","doi-asserted-by":"publisher","DOI":"10.17245\/jdapm.2024.24.6.385","author":"FC Peedikayil","year":"2024","unstructured":"Peedikayil FC, Kottayi S, Aravind A, et al. Efficacy of local anesthesia with cryotherapy on teeth with molar incisal hypomineralization: a randomized control trial. J Dent Anesth Pain Med. 2024. https:\/\/doi.org\/10.17245\/jdapm.2024.24.6.385.","journal-title":"J Dent Anesth Pain Med"},{"key":"1100_CR34","doi-asserted-by":"publisher","DOI":"10.4103\/njms.NJMS_237_20","author":"M Rahul","year":"2021","unstructured":"Rahul M, Tewari N, Mathur V, et al. Evidence mapping and quality analysis of published dental literature on COVID-19\u2014a systematic review. Natl J Maxillofac Surg. 2021. https:\/\/doi.org\/10.4103\/njms.NJMS_237_20.","journal-title":"Natl J Maxillofac Surg"},{"key":"1100_CR35","doi-asserted-by":"publisher","DOI":"10.17796\/1053-4628-40.3.207","author":"M Restrepo","year":"2016","unstructured":"Restrepo M, Jeremias F, Santos-Pinto L, et al. Effect of fluoride varnish on enamel remineralization in anterior teeth with molar incisor hypomineralization. J Clin Pediatr Dent. 2016. https:\/\/doi.org\/10.17796\/1053-4628-40.3.207.","journal-title":"J Clin Pediatr Dent"},{"key":"1100_CR36","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-020-03459-2","author":"TZC Rolim","year":"2021","unstructured":"Rolim TZC, da Costa TRF, Wambier LMAC, et al. Adhesive restoration of molars affected by molar incisor hypomineralization: a randomized clinical trial. Clin Oral Investig. 2021. https:\/\/doi.org\/10.1007\/s00784-020-03459-2.","journal-title":"Clin Oral Investig"},{"key":"1100_CR37","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-024-04860-z","author":"AE Saad","year":"2024","unstructured":"Saad AE, Alhosainy AY, Abdellatif AM. Evaluation of Silver Diamine Fluoride Modified Atraumatic Restorative Treatment (SMART) on hypomineralized first permanent molar\"- a randomized controlled clinical study. BMC Oral Health. 2024. https:\/\/doi.org\/10.1186\/s12903-024-04860-z.","journal-title":"BMC Oral Health"},{"key":"1100_CR38","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2020.01.020","author":"R Sarkis-Onofre","year":"2020","unstructured":"Sarkis-Onofre R, Poletto-Neto V, Cenci MS, et al. Consort endorsement improves the quality of reports of randomized clinical trials in dentistry. J Clin Epidemiol. 2020. https:\/\/doi.org\/10.1016\/j.jclinepi.2020.01.020.","journal-title":"J Clin Epidemiol"},{"key":"1100_CR39","doi-asserted-by":"publisher","DOI":"10.1007\/s00103-013-1818-y","author":"C Schmucker","year":"2013","unstructured":"Schmucker C, Motschall E, Antes G, Meerpohl JJ. Methods of evidence mapping a systematic review. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2013. https:\/\/doi.org\/10.1007\/s00103-013-1818-y.","journal-title":"Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz"},{"key":"1100_CR40","doi-asserted-by":"publisher","DOI":"10.1159\/000516266","author":"MS Schraverus","year":"2021","unstructured":"Schraverus MS, Oleg\u00e1rio IC, Bonif\u00e1cio CC, et al. Glass ionomer sealants can prevent dental caries but cannot prevent posteruptive breakdown on molars affected by molar incisor hypomineralization: one-year results of a randomized clinical trial. Caries Res. 2021. https:\/\/doi.org\/10.1159\/000516266.","journal-title":"Caries Res"},{"key":"1100_CR41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2024.104919","author":"B Sen Yavuz","year":"2024","unstructured":"Sen Yavuz B, Kaya R, Kodaman Dokumacigil N, et al. Clinical performance of short fiber reinforced composite and glass hybrid on hypomineralized molars: a 36-month randomized split-mouth study. J Dent. 2024. https:\/\/doi.org\/10.1016\/j.jdent.2024.104919.","journal-title":"J Dent"},{"key":"1100_CR42","doi-asserted-by":"publisher","DOI":"10.3233\/BME-211371","author":"B Serez","year":"2022","unstructured":"Serez B, Tu\u011fcu N, Cal\u0131\u015fkan C, et al. Effect of casein phosphopeptide amorphous calcium fluoride phosphate and calcium glycerophosphate on incisors with molar-incisor hypomineralization: a cross-over, randomized clinical trial. Biomed Mater Eng. 2022. https:\/\/doi.org\/10.3233\/BME-211371.","journal-title":"Biomed Mater Eng"},{"key":"1100_CR43","doi-asserted-by":"publisher","DOI":"10.17796\/1053-4625-46.3.4","author":"B Sezer","year":"2022","unstructured":"Sezer B, Kargul B. Effect of remineralization agents on molar-incisor hypomineralization-affected incisors: a randomized controlled clinical trial. J Clin Pediatr Dent. 2022. https:\/\/doi.org\/10.17796\/1053-4625-46.3.4.","journal-title":"J Clin Pediatr Dent"},{"key":"1100_CR44","doi-asserted-by":"publisher","DOI":"10.4103\/jisppd.jisppd_245_23","author":"Y Shah","year":"2023","unstructured":"Shah Y, Deshpande A, Jain A, et al. Effectiveness of resin infiltration (ICON) and microabrasion-remineralization technique with two remineralizing agents (Tooth Mousse and Toothmin) on permanent incisor hypoplasia - a randomized clinical trial. J Indian Soc Pedod Prev Dent. 2023. https:\/\/doi.org\/10.4103\/jisppd.jisppd_245_23.","journal-title":"J Indian Soc Pedod Prev Dent"},{"issue":"5","key":"1100_CR45","first-page":"2703","volume":"16","author":"K Shahnawaz","year":"2024","unstructured":"Shahnawaz K, Anamika A, Soni A, Kumar A. Effect of photobiomodulation on the efficacy of anesthesia in maxillary permanent molar teeth with molar incisor hypomineralization: a randomized clinical trial. Int J Pharm Pharm Sci. 2024;16(5):2703\u20136.","journal-title":"Int J Pharm Pharm Sci"},{"key":"1100_CR46","doi-asserted-by":"publisher","DOI":"10.1007\/s40368-021-00657-8","author":"SK Singh","year":"2022","unstructured":"Singh SK, Goyal A, Gauba K, et al. Full coverage crowns for rehabilitation of MIH affected molars: 24 month randomized clinical trial. Eur Arch Paediatr Dent. 2022. https:\/\/doi.org\/10.1007\/s40368-021-00657-8.","journal-title":"Eur Arch Paediatr Dent"},{"key":"1100_CR47","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2016.05.015","author":"B Snilstveit","year":"2013","unstructured":"Snilstveit B, Vojtkova M, Bhavsar A, Gaarder M. Evidence gap maps\u2014a tool for promoting evidence-informed policy and prioritizing future research. J Clin Epidemiol. 2013. https:\/\/doi.org\/10.1016\/j.jclinepi.2016.05.015.","journal-title":"J Clin Epidemiol"},{"key":"1100_CR48","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12186002","author":"S Srivastav","year":"2023","unstructured":"Srivastav S, Tewari N, Antonarakis GS, et al. Evidence mapping and quality analysis of systematic reviews on various aspects related to cleft lip and palate. J Clin Med. 2023. https:\/\/doi.org\/10.3390\/jcm12186002.","journal-title":"J Clin Med"},{"key":"1100_CR49","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l4898","author":"JAC Sterne","year":"2019","unstructured":"Sterne JAC, Savovi\u0107 J, Page MJ, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019. https:\/\/doi.org\/10.1136\/bmj.l4898.","journal-title":"BMJ"},{"key":"1100_CR50","doi-asserted-by":"publisher","DOI":"10.1111\/edt.12606","author":"N Tewari","year":"2021","unstructured":"Tewari N, Mathur VP, Kaur A, et al. Evidence mapping and quality assessment of systematic reviews in dental traumatology. Dent Traumatol. 2021. https:\/\/doi.org\/10.1111\/edt.12606.","journal-title":"Dent Traumatol"},{"key":"1100_CR51","doi-asserted-by":"publisher","DOI":"10.4103\/jisppd.jisppd_375_23","author":"AM Thomas","year":"2023","unstructured":"Thomas AM, George S, Anandaraj S. Anesthetic efficacy of 4% articaine versus 2% lignocaine in root canal treatment of teeth with molar incisor hypomineralization. J Indian Soc Pedod Prev Dent. 2023. https:\/\/doi.org\/10.4103\/jisppd.jisppd_375_23.","journal-title":"J Indian Soc Pedod Prev Dent"},{"key":"1100_CR52","doi-asserted-by":"publisher","DOI":"10.1590\/1678-7757-2022er001","author":"F Vicioni-Marques","year":"2022","unstructured":"Vicioni-Marques F, Paula-Silva FWG, Carvalho MR, et al. Preemptive analgesia with ibuprofen increases anesthetic efficacy in children with severe molar: a triple-blind randomized clinical trial. J Appl Oral Sci. 2022. https:\/\/doi.org\/10.1590\/1678-7757-2022er001.","journal-title":"J Appl Oral Sci"},{"key":"1100_CR53","doi-asserted-by":"publisher","DOI":"10.1159\/000047479","author":"KL Weerheijm","year":"2001","unstructured":"Weerheijm KL, J\u00e4levik B, Alaws UA. Molar-incisor hypomineralization. Caries Res. 2001. https:\/\/doi.org\/10.1159\/000047479.","journal-title":"Caries Res"},{"key":"1100_CR54","doi-asserted-by":"publisher","DOI":"10.1186\/s40001-022-00717-9","author":"X Zhao","year":"2022","unstructured":"Zhao X, Jiang H, Yin J, et al. Changing trends in clinical research literature on PubMed database from 1991 to 2020. Eur J Med Res. 2022. https:\/\/doi.org\/10.1186\/s40001-022-00717-9.","journal-title":"Eur J Med Res"},{"key":"1100_CR55","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-023-03944-6","author":"S Zhao","year":"2023","unstructured":"Zhao S, Zhou L, Jiang Y, Xing X. Er:YAG laser therapy in combination with GLUMA desensitizer reduces dentin hypersensitivity in children with molar-incisor hypomineralization: a randomized clinical trial. Lasers Med Sci. 2023. https:\/\/doi.org\/10.1007\/s10103-023-03944-6.","journal-title":"Lasers Med Sci"}],"container-title":["European Archives of Paediatric Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40368-025-01100-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40368-025-01100-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40368-025-01100-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T08:51:09Z","timestamp":1763715069000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40368-025-01100-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,24]]},"references-count":55,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["1100"],"URL":"https:\/\/doi.org\/10.1007\/s40368-025-01100-y","relation":{},"ISSN":["1818-6300","1996-9805"],"issn-type":[{"value":"1818-6300","type":"print"},{"value":"1996-9805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,24]]},"assertion":[{"value":"28 May 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 August 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 August 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that there are no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}