{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T20:09:33Z","timestamp":1793650173017,"version":"4.5.1"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100004769","name":"Universit\u00e0 degli Studi di Pavia","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004769","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Ultrasound"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Thickening of the gallbladder wall is often associated with acute or chronic cholecystitis, adenomyomatosis and gallbladder carcinoma or seen in the context of liver and systemic diseases (acute hepatitis, cirrhosis, sepsis). Here we present a case of a 61 y.o. man with focal thickening of the gallbladder wall, in whom all imaging techniques were inconclusive. Pathological examination of the resected gallbladder revealed acute-on-chronic cholecystitis. We describe focal acute cholecystitis in absence of the classic clinical and imaging findings (Murphy\u2019s sign, fever, gallstones, hydrops, pericholecystic fluid) and mimicking a gallbladder carcinoma.<\/jats:p>","DOI":"10.1007\/s40477-025-00995-z","type":"journal-article","created":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T21:22:03Z","timestamp":1739481723000},"page":"187-191","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Focal acute cholecystitis misdiagnosed as gallbladder carcinoma"],"prefix":"10.1007","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7815-7559","authenticated-orcid":false,"given":"G. L.","family":"D\u2019Alessandro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Ancona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Dellafiore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Raimondi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Gangemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Arpa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Poma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Above","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,2,13]]},"reference":[{"issue":"1","key":"995_CR1","doi-asserted-by":"publisher","first-page":"W1","DOI":"10.2214\/AJR.12.10386","volume":"202","author":"GJ Runner","year":"2014","unstructured":"Runner GJ, Corwin MT, Siewert B, Eisenberg RL (2014) Gallbladder wall thickening. AJR Am J Roentgenol 202(1):W1\u2013W12. https:\/\/doi.org\/10.2214\/AJR.12.10386","journal-title":"AJR Am J Roentgenol"},{"issue":"40","key":"995_CR2","doi-asserted-by":"publisher","first-page":"6163","DOI":"10.3748\/wjg.v26.i40.6163.PMID:33177791;PMCID:PMC7596646","volume":"26","author":"P Gupta","year":"2020","unstructured":"Gupta P, Marodia Y, Bansal A, Kalra N, Kumar-M P, Sharma V, Dutta U, Sandhu MS (2020) Imaging-based algorithmic approach to gallbladder wall thickening. World J Gastroenterol 26(40):6163\u20136181. https:\/\/doi.org\/10.3748\/wjg.v26.i40.6163.PMID:33177791;PMCID:PMC7596646","journal-title":"World J Gastroenterol"},{"issue":"10","key":"995_CR3","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1001\/jama.2022.2350","volume":"327","author":"JR Gallaher","year":"2022","unstructured":"Gallaher JR, Charles A (2022) Acute cholecystitis: a review. JAMA 327(10):965\u2013975. https:\/\/doi.org\/10.1001\/jama.2022.2350","journal-title":"JAMA"},{"issue":"1","key":"995_CR4","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1002\/jhbp.515","volume":"25","author":"M Yokoe","year":"2018","unstructured":"Yokoe M, Hata J, Takada T, Strasberg SM, Asbun HJ, Wakabayashi G, Kozaka K, Endo I, Deziel DJ, Miura F, Okamoto K, Hwang TL, Huang WS, Ker CG, Chen MF, Han HS, Yoon YS, Choi IS, Yoon DS, Noguchi Y, Shikata S, Ukai T, Higuchi R, Gabata T, Mori Y, Iwashita Y, Hibi T, Jagannath P, Jonas E, Liau KH, Dervenis C, Gouma DJ, Cherqui D, Belli G, Garden OJ, Gim\u00e9nez ME, de Santiba\u00f1es E, Suzuki K, Umezawa A, Supe AN, Pitt HA, Singh H, Chan ACW, Lau WY, Teoh AYB, Honda G, Sugioka A, Asai K, Gomi H, Itoi T, Kiriyama S, Yoshida M, Mayumi T, Matsumura N, Tokumura H, Kitano S, Hirata K, Inui K, Sumiyama Y, Yamamoto M (2018) Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis (with videos). J Hepatobiliary Pancreat Sci 25(1):41\u201354. https:\/\/doi.org\/10.1002\/jhbp.515","journal-title":"J Hepatobiliary Pancreat Sci"},{"issue":"4","key":"995_CR5","doi-asserted-by":"publisher","first-page":"W367","DOI":"10.2214\/AJR.10.4340","volume":"196","author":"OJ O'Connor","year":"2011","unstructured":"O\u2019Connor OJ, Maher MM (2011) Imaging of cholecystitis. AJR Am J Roentgenol 196(4):W367\u2013W374. https:\/\/doi.org\/10.2214\/AJR.10.4340","journal-title":"AJR Am J Roentgenol"},{"issue":"2","key":"995_CR6","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.annonc.2022.10.506","volume":"34","author":"A Vogel","year":"2023","unstructured":"Vogel A, Bridgewater J, Edeline J, Kelley RK, Kl\u00fcmpen HJ, Malka D, Primrose JN, Rimassa L, Stenzinger A, Valle JW, Ducreux M, ESMO Guidelines Committee (2023) Biliary tract cancer: ESMO clinical practice guideline for diagnosis, treatment and follow-up. Ann Oncol 34(2):127\u2013140. https:\/\/doi.org\/10.1016\/j.annonc.2022.10.506","journal-title":"Ann Oncol"},{"issue":"7","key":"995_CR7","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.6037","volume":"10","author":"EJ Spartz","year":"2022","unstructured":"Spartz EJ, Wheelwright M, Mettler T, Amin K, Azeem N, Hassan M, Ankeny J, Harmon JV (2022) Evaluation of abnormal gallbladder imaging findings: Surgical management and pathologic correlations in early-stage gallbladder cancer. Clin Case Rep 10(7):e6037. https:\/\/doi.org\/10.1002\/ccr3.6037","journal-title":"Clin Case Rep"},{"issue":"2","key":"995_CR8","doi-asserted-by":"publisher","first-page":"e2","DOI":"10.1055\/a-0586-1107","volume":"39","author":"PS Sidhu","year":"2018","unstructured":"Sidhu PS, Cantisani V, Dietrich CF, Gilja OH, Saftoiu A, Bartels E, Bertolotto M, Calliada F, Clevert DA, Cosgrove D, Deganello A, D\u2019Onofrio M, Drudi FM, Freeman S, Harvey C, Jenssen C, Jung EM, Klauser AS, Lassau N, Meloni MF, Leen E, Nicolau C, Nolsoe C, Piscaglia F, Prada F, Prosch H, Radzina M, Savelli L, Weskott HP, Wijkstra H (2018) The EFSUMB Guidelines and Recommendations for the Clinical Practice of Contrast-Enhanced Ultrasound (CEUS) in Non-Hepatic Applications: Update 2017 (Long Version). Ultraschall Med 39(2):e2\u2013e44. https:\/\/doi.org\/10.1055\/a-0586-1107","journal-title":"Ultraschall Med"},{"issue":"1","key":"995_CR9","doi-asserted-by":"publisher","first-page":"e96","DOI":"10.1016\/j.crad.2015.10.016","volume":"71","author":"SW Kim","year":"2016","unstructured":"Kim SW, Kim HC, Yang DM, Ryu JK, Won KY (2016) Gallbladder carcinoma: causes of misdiagnosis at CT. Clin Radiol 71(1):e96-109. https:\/\/doi.org\/10.1016\/j.crad.2015.10.016","journal-title":"Clin Radiol"}],"container-title":["Journal of Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40477-025-00995-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40477-025-00995-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40477-025-00995-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T01:57:57Z","timestamp":1743299877000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40477-025-00995-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,13]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,3]]}},"alternative-id":["995"],"URL":"https:\/\/doi.org\/10.1007\/s40477-025-00995-z","relation":{},"ISSN":["1876-7931"],"issn-type":[{"value":"1876-7931","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,13]]},"assertion":[{"value":"3 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 February 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This is a case report, no ethical approval is required.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The patient gave only verbal consent to publication. All details that might disclose patient identity are anonymized.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publication"}}]}}