{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T16:18:49Z","timestamp":1778084329964,"version":"3.51.4"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T00:00:00Z","timestamp":1778025600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T00:00:00Z","timestamp":1778025600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Ultrasound"],"DOI":"10.1007\/s40477-026-01158-4","type":"journal-article","created":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T15:43:31Z","timestamp":1778082211000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ultrasound assessment of diaphragmatic structure and function before and after orthotopic liver transplantation in MNGIE"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4509-0586","authenticated-orcid":false,"given":"A.","family":"Bianchini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Boschetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Vitale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Adamo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Prosperi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Siniscalchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,5,6]]},"reference":[{"key":"1158_CR1","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1002\/jimd.12300","volume":"44","author":"M Hirano","year":"2021","unstructured":"Hirano M, Carelli V, De Giorgio R et al (2021) Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): position paper on diagnosis, prognosis, and treatment. J Inherit Metab Dis 44:376\u2013387","journal-title":"J Inherit Metab Dis"},{"key":"1158_CR2","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1002\/ana.24724","volume":"80","author":"R De Giorgio","year":"2016","unstructured":"De Giorgio R, Pironi L, Rinaldi R et al (2016) Liver transplantation for mitochondrial neurogastrointestinal encephalomyopathy. Ann Neurol 80:448\u2013455","journal-title":"Ann Neurol"},{"key":"1158_CR3","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.mito.2017.02.006","volume":"34","author":"R D\u2019Angelo","year":"2017","unstructured":"D\u2019Angelo R, Rinaldi R, Pironi L et al (2017) Liver transplant reverses biochemical imbalance in mitochondrial neurogastrointestinal encephalomyopathy. Mitochondrion 34:101\u2013102","journal-title":"Mitochondrion"},{"key":"1158_CR4","doi-asserted-by":"publisher","first-page":"3326","DOI":"10.1093\/brain\/awr245","volume":"134","author":"C Garone","year":"2011","unstructured":"Garone C, Hirano M (2011) Clinical and genetic spectrum of mitochondrial neurogastrointestinal encephalomyopathy. Brain 134:3326\u20133332","journal-title":"Brain"},{"key":"1158_CR5","doi-asserted-by":"publisher","first-page":"1525","DOI":"10.1053\/j.gastro.2018.12.011","volume":"156","author":"G Corazza","year":"2019","unstructured":"Corazza G, Pagan C, Hardy G et al (2019) MyoNeuroGastroIntestinal encephalopathy: natural history and means for early diagnosis. Gastroenterology 156:1525\u20131527","journal-title":"Gastroenterology"},{"key":"1158_CR6","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.ymgme.2020.03.001","volume":"130","author":"K Kripps","year":"2020","unstructured":"Kripps K, Nakayuenyongsuk W, Shayota BJ et al (2020) Successful liver transplantation in mitochondrial neurogastrointestinal encephalomyopathy. Mol Genet Metab 130:58\u201364","journal-title":"Mol Genet Metab"},{"issue":"1","key":"1158_CR7","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1007\/s00134-016-4524-z","volume":"43","author":"M Zambon","year":"2017","unstructured":"Zambon M, Greco M, Bocchino S et al (2017) Assessment of diaphragmatic dysfunction in the critically ill patient with ultrasound: a systematic review. Intensive Care Med 43(1):29\u201338","journal-title":"Intensive Care Med"},{"issue":"2","key":"1158_CR8","doi-asserted-by":"publisher","first-page":"e24","DOI":"10.1097\/CCM.0000000000005739","volume":"51","author":"D Truong","year":"2023","unstructured":"Truong D, Abo S, Whish-Wilson GA et al (2023) Methodological and clinimetric evaluation of inspiratory respiratory muscle ultrasound in the critical care setting: a systematic review and meta-analysis. Crit Care Med 51(2):e24\u2013e36","journal-title":"Crit Care Med"},{"issue":"4","key":"1158_CR9","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1007\/s00134-015-3687-3","volume":"41","author":"EC Goligher","year":"2015","unstructured":"Goligher EC, Laghi F, Detsky ME et al (2015) Measuring diaphragm thickness with ultrasound in mechanically ventilated patients: feasibility, reproducibility, and validity. Intensive Care Med 41(4):642\u2013649","journal-title":"Intensive Care Med"},{"issue":"1","key":"1158_CR10","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-022-03975-5","volume":"26","author":"ME Haaksma","year":"2022","unstructured":"Haaksma ME, Smit JM, Boussuges A et al (2022) EXpert consensus on diaphragm ultrasonography in the critically ill (EXODUS): a Delphi consensus statement on the measurement of diaphragm ultrasound-derived parameters in a critical care setting. Crit Care 26(1):99","journal-title":"Crit Care"},{"issue":"9","key":"1158_CR11","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1136\/thoraxjnl-2016-209459","volume":"72","author":"BP Dub\u00e9","year":"2017","unstructured":"Dub\u00e9 BP, Dres M, Mayaux J et al (2017) Ultrasound evaluation of diaphragm function in mechanically ventilated patients: comparison to phrenic stimulation and prognostic implications. Thorax 72(9):811\u2013818","journal-title":"Thorax"},{"key":"1158_CR12","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.742703","volume":"8","author":"A Boussuges","year":"2021","unstructured":"Boussuges A, Rives S, Finance J et al (2021) Ultrasound assessment of diaphragm thickness and thickening: reference values and limits of normality when in a seated position. Front Med 8:742703","journal-title":"Front Med"},{"issue":"5","key":"1158_CR13","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1159\/000506016","volume":"99","author":"J Spiesshoefer","year":"2020","unstructured":"Spiesshoefer J, Herkenrath S, Henke C et al (2020) Evaluation of respiratory muscle strength and diaphragm ultrasound: normative values, theoretical considerations, and practical recommendations. Respiration 99(5):369\u2013381","journal-title":"Respiration"},{"key":"1158_CR14","doi-asserted-by":"publisher","DOI":"10.1183\/16000617.0089-2025","volume":"34","author":"I Neto Silva","year":"2025","unstructured":"Neto Silva I, Bennett C, Duarte JA, Bendjelid K (2025) Ultrasound innovations in diaphragm assessment: an integrative review of expanding clinical applications. Eur Respir Rev 34:250089","journal-title":"Eur Respir Rev"},{"key":"1158_CR15","doi-asserted-by":"publisher","first-page":"3702","DOI":"10.1007\/s00415-020-10051-x","volume":"267","author":"R D\u2019Angelo","year":"2020","unstructured":"D\u2019Angelo R, Boschetti E, Amore G et al (2020) Liver transplantation in mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): clinical long-term follow-up and pathogenic implications. J Neurol 267:3702\u20133710","journal-title":"J Neurol"},{"key":"1158_CR16","doi-asserted-by":"publisher","first-page":"C947","DOI":"10.1152\/ajpcell.00389.2001","volume":"282","author":"M Papetti","year":"2002","unstructured":"Papetti M, Herman IM (2002) Mechanisms of normal and tumor-derived angiogenesis. Am J Physiol Cell Physiol 282:C947\u2013C970","journal-title":"Am J Physiol Cell Physiol"},{"key":"1158_CR17","doi-asserted-by":"publisher","first-page":"451","DOI":"10.3389\/fbioe.2019.00451","volume":"7","author":"S Dikici","year":"2019","unstructured":"Dikici S, AldemirDikici B, Bhaloo SI et al (2019) Assessment of the angiogenic potential of 2-deoxy-D-ribose using a novel approach. Front Bioeng Biotechnol 7:451","journal-title":"Front Bioeng Biotechnol"},{"key":"1158_CR18","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics15070870","volume":"15","author":"A Bianchini","year":"2025","unstructured":"Bianchini A, Pintus L, Vitale G et al (2025) Lung ultrasound in mechanical ventilation: a purposive review. Diagnostics Basel 15:870","journal-title":"Diagnostics Basel"}],"container-title":["Journal of Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40477-026-01158-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40477-026-01158-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40477-026-01158-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T15:43:31Z","timestamp":1778082211000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40477-026-01158-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,6]]},"references-count":18,"alternative-id":["1158"],"URL":"https:\/\/doi.org\/10.1007\/s40477-026-01158-4","relation":{},"ISSN":["1876-7931"],"issn-type":[{"value":"1876-7931","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,6]]},"assertion":[{"value":"23 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflicts of interest related to the content of this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. According to institutional policies and national regulations, ethical committee approval was not required for this case report.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent and ethical approval"}}]}}