{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:52:21Z","timestamp":1791071541126,"version":"4.1.0"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T00:00:00Z","timestamp":1790985600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T00:00:00Z","timestamp":1790985600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Ultrasound"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To describe the pivotal role of conventional B-mode and contrast-enhanced ultrasound (CEUS) in identifying and characterizing rare visceral manifestations of\n                      <jats:italic>Bartonella henselae<\/jats:italic>\n                      infection in an immunocompetent individual.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case report<\/jats:title>\n                    <jats:p>\n                      A 67-year-old immunocompetent female presented with a diffuse maculopapular exanthema, fever, and left inguinal lymphadenopathy following a cat scratch. Conventional ultrasound revealed multiple subcentimetric hypoechoic areas in both hepatic lobes and the spleen, along with a necrotic\u2013colliquative nodal mass in the left Scarpa's triangle. CEUS demonstrated an inflammatory\/necrotic perfusion pattern characterized by absence of contrast enhancement, appearing as avascular, non-enhancing necrotic cores suggestive of granulomatous lesions. The clinical suspicion was confirmed by positive\n                      <jats:italic>Bartonella henselae<\/jats:italic>\n                      serology. Clinical resolution was achieved after a 1-month course of doxycycline.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Visceral cat scratch disease should be considered in the differential diagnosis of multiple hepatosplenic lesions even in fully immunocompetent hosts. Multiparametric ultrasound, particularly CEUS, represents an essential, non-invasive standard tool for early detection, definitive characterization, and radiation-free therapeutic monitoring.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s40477-026-01234-9","type":"journal-article","created":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T06:37:38Z","timestamp":1791009458000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ultrasound features of visceral cat scratch disease: a rare case of granulomatous hepatosplenic bartonellosis in an immunocompetent patient"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1262-123X","authenticated-orcid":false,"given":"Giorgia","family":"Russo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabetta","family":"Biasini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Missale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,3]]},"reference":[{"key":"1234_CR1","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1093\/ajcp\/80.5.714","volume":"80","author":"MH Stoler","year":"1983","unstructured":"Stoler MH, Bonfiglio TA, Steigbigel RT, Pereira M (1983) An atypical subcutaneous infection associated with acquired immune deficiency syndrome. 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Cureus 13(2):e13219","journal-title":"Cureus"},{"key":"1234_CR8","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/1471-2334-12-17","volume":"12","author":"TR VanderHeyden","year":"2012","unstructured":"VanderHeyden TR, Yong SL, Breitschwerdt EB et al (2012) Granulomatous hepatitis due to Bartonella henselae infection in an immunocompetent patient. BMC Infect Dis 12:17","journal-title":"BMC Infect Dis"},{"issue":"17","key":"1234_CR9","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1097\/MD.0000000000000089","volume":"93","author":"JC Garc\u00eda","year":"2014","unstructured":"Garc\u00eda JC, N\u00fa\u00f1ez MJ, Castro B, Fern\u00e1ndez JM, Portillo A, Oteo JA (2014) Hepatosplenic cat scratch disease in immunocompetent adults: report of 3 cases and review of the literature. Medicine (Baltimore) 93(17):267\u2013279","journal-title":"Medicine (Baltimore)"},{"issue":"10","key":"1234_CR10","doi-asserted-by":"publisher","first-page":"2154","DOI":"10.1007\/s42399-021-00940-1","volume":"3","author":"D Tirotta","year":"2021","unstructured":"Tirotta D, Mazzeo V, Nizzoli M (2021) Hepatosplenic cat scratch disease: description of two cases undergoing contrast-enhanced ultrasound for diagnosis and follow-up and systematic literature review. 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