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Saini is an employee of Fortrea Inc. and reports consulting fees from the European Commission, and stock and\/or other ownership interests in Labcorp Inc., Fortrea Inc., and Quantum Health Analytics (UK) Ltd., outside the submitted work. Amanda Nogueira, Jennifer Brondon, Konstantin Haradinov, Krane Huang, Debasri Mukherjee, Laura Vidal, Chinmayee Joshi, Soma Das, Arun K. Mankan, Archana Munje, Begona de las Heras, Daniel Gandia, and Isagani Chico are employees of Fortrea Inc. Kyle C. Strickland and Shakti Ramkissoon are employees of Labcorp Inc. Julien Taieb has received honoraria as a speaker and\/or in an advisory role from AMGEN, Astellas, AstraZeneca, BMS, Boehringer, Merck KGaA, MSD, Novartis, ONO Pharmaceuticals, Pierre Fabre, Roche Genentech, Sanofi, Servier, and Takeda. Kamal S. Saini is an Editorial Board member of Oncology and Therapy. Kamal S. Saini was not involved in the selection of peer reviewers for the manuscript or any subsequent editorial decisions. Srinivasan Gopalakrishnan, Smita Agarwal, Rebecca Brookes, Rajeev Prasad, Brajendra Prasad Singh, Fahmi Sabr Raza, Sharadchandra K. Prasad, Judith Perez, Anumeha Prasad, and Debashis Sarker report no conflicts of interest.","order":1,"name":"Ethics","label":"Conflict of Interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was performed as a retrospective secondary analysis of de-identified data generated during routine clinical testing, conducted under the PRecision Oncology Biomarker Evidence (PROBE) protocol (POET-0001), which was reviewed and approved by an independent institutional review board (Western Institutional Review Board\u2013Copernicus Group[WCG IRB]; protocol #1340120), including waivers of informed consent and Health Insurance Portability and Accountability Act (HIPAA) authorization. Data were handled in accordance with applicable privacy regulations, including the HIPAA, under an institutional data use agreement.","order":2,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}}]}}