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He has previously held a \u201cR\u00edo Hortega\u201d grant from Instituto de Salud Carlos III (Spanish Ministry of Economy and Competitiveness).KM has no conflicts of interest. JCL has received grant support from Instituto de Salud Carlos III (Spanish Ministry of Economy, Industry, and Competitiveness), CIBERSAM, Fundaci\u00f3n Alicia Koplowitz, and Fundaci\u00f3n Mutua Madrile\u00f1a. JLC and MDM have been a consultant to or have received honoraria or grants from AstraZeneca, Bristol-Myers Squibb, CIBERSAM, Janssen Cilag, Lundbeck, Otsuka, Pfizer, and Roche.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were under the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}