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The <jats:italic>pathoplasty model<\/jats:italic> theorizes that personality might shape symptomatic presentation and thus affect therapeutic outcomes, but more research is needed. The present study aimed at investigating the predictive value of a broad spectrum of personality traits in determining AN and BN treatment outcomes, considering both the statistical and clinical significance of the therapeutic change.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Eighty-four female patients with AN and BN treated in a residential program were evaluated at treatment onset using the Shedler-Westen Assessment Procedure-200\u2014a clinician-rated measure of personality disorders and healthy personality functioning. At both intake and discharge, patients completed the Eating Disorder Inventory-3 to assess eating symptoms and the Outcome Questionnaire-45.2 to evaluate overall impairment.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Considering overall ED symptomatic change, multiple regression analyses showed that, even when controlling for baseline symptoms and DSM-5 categories, schizoid (<jats:italic>B<\/jats:italic>\u2009=\u20090.41, <jats:italic>p<\/jats:italic>\u2009\u2264\u20090.01), avoidant (<jats:italic>B<\/jats:italic>\u2009=\u20090.31, <jats:italic>p<\/jats:italic>\u2009\u2264\u20090.05), and paranoid (<jats:italic>B<\/jats:italic>\u2009=\u20090.25, <jats:italic>p<\/jats:italic>\u2009\u2264\u20090.05) personality features predicted worse therapeutic outcomes. Similar results were found when applying the clinical significance approach, with the emotionally dysregulated factor as an additional negative predictor of significant\/reliable change (<jats:italic>B<\/jats:italic>\u2009=\u2009\u2009\u2212\u20090.09; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). Healthy personality functioning predicted better therapeutic outcomes (<jats:italic>B<\/jats:italic>\u2009=\u2009\u2009\u2212\u20090.34, <jats:italic>p<\/jats:italic>\u2009\u2264\u20090.001).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Pathoplastic models and personality-based research in this clinical population have the potential to inform effective treatment strategies by targeting relevant individual factors.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Level of evidence<\/jats:title>\n                <jats:p>Level III, longitudinal\u00a0cohort study.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s40519-020-01023-1","type":"journal-article","created":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T13:04:20Z","timestamp":1602594260000},"page":"1195-1209","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Personality as a predictor of symptomatic change in a residential treatment setting for anorexia nervosa and bulimia nervosa"],"prefix":"10.1007","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6394-6018","authenticated-orcid":false,"given":"Laura","family":"Muzi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Tieghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele Angelo","family":"Rugo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vittorio","family":"Lingiardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,10,13]]},"reference":[{"key":"1023_CR1","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1001\/archgenpsychiatry.2011.74","volume":"68","author":"J Arcelus","year":"2011","unstructured":"Arcelus J, Mitchell AJ, Wales J, Nielsen S (2011) Mortality rates in patients with anorexia nervosa and other eating disorders: a meta-analysis of 36 studies. 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