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Descriptive statistics, crude, and adjusted logistic regression models were used to assess the association between zinc deficiency (&lt;\u200955 mcg\/dL) and anemia (&lt;\u200913.6\u00a0g\/dL in males [M] and\u2009&lt;\u200911.8\u00a0g\/dL in females [F]).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 87 males and 450 females met eligibility criteria (age 15.98\u2009\u00b1\u20092.81, 59.4% anorexia nervosa; admission body mass index 17.49\u2009\u00b1\u20092.82). In unadjusted comparisons, plasma zinc in males and females were not statistically different (M 64.88\u2009\u00b1\u200914.89 mcg\/dL vs F 63.81\u2009\u00b1\u200913.96 mcg\/dL, <jats:italic>p<\/jats:italic>\u2009=\u20090.517); moreover, there were no differences in the percentage of males and females with zinc deficiency (M 24.14% vs F 24.89%). However, a greater percentage of males than females were anemic (M 50.00% vs F 17.61%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), with similar findings in the subgroup with anorexia nervosa. In logistic regression models stratified by sex and eating disorder diagnosis, zinc deficiency was significantly associated with anemia in males (AOR 3.43, 95% CI 1.16, 10.13), but not females (AOR 1.47, 95% CI 0.86, 2.54).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>For the first time, we demonstrate that zinc deficiency is equally severe in males compared to females hospitalized with medical complications from eating disorders, with nearly a quarter of inpatients experiencing zinc deficiency. Anemia is more common in males than females hospitalized with eating disorders.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Level of evidence<\/jats:title>\n                <jats:p>Level V: descriptive cross-sectional study.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s40519-022-01396-5","type":"journal-article","created":{"date-parts":[[2022,5,28]],"date-time":"2022-05-28T03:28:22Z","timestamp":1653708502000},"page":"2911-2917","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Sex differences and associations between zinc deficiency and anemia among hospitalized adolescents and young adults with eating disorders"],"prefix":"10.1007","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6541-0604","authenticated-orcid":false,"given":"Jason M.","family":"Nagata","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Bojorquez-Ramirez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle T.","family":"Ganson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine M.","family":"McDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa I.","family":"Machen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Downey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara M.","family":"Buckelew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea K.","family":"Garber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,5,28]]},"reference":[{"key":"1396_CR1","doi-asserted-by":"publisher","first-page":"792","DOI":"10.3390\/NU11040792","volume":"11","author":"M Hanachi","year":"2019","unstructured":"Hanachi M, Dicembre M, Rives-Lange C et al (2019) Micronutrients deficiencies in 374 severely malnourished anorexia nervosa inpatients. 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The Institutional Review Board (IRB) of the University of California, San Francisco approved this study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"This research study was conducted retrospectively from data obtained for clinical purposes. We consulted extensively with the IRB of the University of California, San Francisco who determined that our study did not need informed consent.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}}]}}