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Thus, the aim of this paper was to critically review the current scientific findings regarding the role of microbiota in anorexia nervosa.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A systematic study of peer-reviewed literature published in four databases between 2009 and 2022 was conducted according to PRISMA guidelines. Both human and animal studies were included.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 18 studies were included. In animal models, both the preclinical and clinical findings were inconsistent regarding microbiota composition, faecal metabolite concentrations, and the effects of human faecal microbiota transplants.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The methodological limitations, lack of standardisation, and conceptual ambiguity hinder the analysis of microbiota as a key explanatory factor for AN.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Level of evidence<\/jats:title>\n                <jats:p>Level I, systematic review.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s40519-023-01529-4","type":"journal-article","created":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T22:35:37Z","timestamp":1675895737000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Anorexia nervosa and microbiota: systematic review and critical appraisal"],"prefix":"10.1007","volume":"28","author":[{"given":"Naomi","family":"Garcia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilio","family":"Gutierrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,2,8]]},"reference":[{"issue":"11","key":"1529_CR1","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1177\/0706743719874168","volume":"64","author":"MI Butler","year":"2019","unstructured":"Butler MI, M\u00f6rkl S, Sandhu KV, Cryan JF, Dinan TG (2019) The gut microbiome and mental health: what should we tell our patients? 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