{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T19:55:16Z","timestamp":1790884516023,"version":"4.1.0"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:00:00Z","timestamp":1682553600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:00:00Z","timestamp":1682553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"The research group of Health psychology at the Univeristy of Troms\u00f8"},{"name":"The research group of Health psychology at the University of Troms\u00f8"},{"name":"The research group Health and Exercise in a Life course Perspective (HELP) at the University of South-Eastern Norway"},{"name":"Ostfold University College"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eat Weight Disord"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>Chaotic eating and purging behavior pose a risk to the metabolic health of women with bulimia nervosa (BN) and binge-eating disorder (BED). This study reports on one-year changes in blood markers of metabolic health and thyroid hormones in women with BN or BED attending two different treatments.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>These are secondary analyses from a randomized controlled trial of 16-week group treatment of either physical exercise and dietary therapy (PED-t) or cognitive behavior therapy (CBT). Blood samples collected at pre-treatment, week eight, post-treatment, and at 6- and 12-month follow-ups were analyzed for glucose, lipids (triglycerides (TG), total cholesterol (TC), LDL cholesterol (LDL-c), HDL cholesterol (HDL-c), apolipoprotein A (ApoA) and apolipoprotein B (ApoB) lipoproteins), and thyroid hormones (thyroxine (T4), thyroid stimulating hormone (TSH), and thyroperoxidase antibodies).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Result<\/jats:title>\n                <jats:p>The average levels of blood glucose, lipids and thyroid hormones were within the recommended range, but clinical levels of TC and LDL-c were detected in 32.5% and 39.1%, respectively. More women with BED compared with BN had low HDL-c, and a larger increase over time in TC and TSH. No significant differences occurred between PED-t and CBT at any measurement. Exploratory moderator analyses indicated a more unfavorable metabolic response at follow-up among treatment non-responders.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The proportion of women with impaired lipid profiles and unfavorable lipid changes, suggests active monitoring with necessary management of the metabolic health of women with BN or BED, as recommended by metabolic health guidelines.<\/jats:p>\n                <jats:p><jats:italic>Level of evidence:<\/jats:italic> Level I: Evidence obtained from a randomized, experimental trial.<\/jats:p>\n                <jats:p><jats:italic>Trial registration number:<\/jats:italic> This trial was prospectively registered in the Norwegian Regional Committee for Medical and Health Research Ethics on December 16, 2013, with the identifier number 2013\/1871, and in Clinical Trials on February 17, 2014, with the identifier number NCT02079935.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s40519-023-01567-y","type":"journal-article","created":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T15:02:23Z","timestamp":1682607743000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Metabolic profile in women with bulimia nervosa or binge-eating disorder before and after treatment: secondary analysis from the randomized PED-t trial"],"prefix":"10.1007","volume":"28","clinical-trial-number":[{"clinical-trial-number":"nct02079935","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3687-583X","authenticated-orcid":false,"given":"Therese Fostervold","family":"Mathisen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorunn","family":"Sundgot-Borgen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan H.","family":"Rosenvinge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solfrid","family":"Bratland-Sanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mette","family":"Svendsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunn","family":"Pettersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KariAnne","family":"Vrabel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oddgeir","family":"Friborg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,4,27]]},"reference":[{"issue":"6","key":"1567_CR1","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1097\/yco.0000000000000278","volume":"29","author":"A Keski-Rahkonen","year":"2016","unstructured":"Keski-Rahkonen A, Mustelin L (2016) Epidemiology of eating disorders in Europe: prevalence, incidence, comorbidity, course, consequences, and risk factors. Curr Opin Psychiatry 29(6):340\u2013345. https:\/\/doi.org\/10.1097\/yco.0000000000000278","journal-title":"Curr Opin Psychiatry"},{"issue":"10","key":"1567_CR2","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1176\/appi.ajp.2012.12010147","volume":"169","author":"CM Bulik","year":"2012","unstructured":"Bulik CM et al (2012) The changing \u201cweightscape\u201d of bulimia nervosa. Am J Psychiatry 169(10):1031\u20131036. https:\/\/doi.org\/10.1176\/appi.ajp.2012.12010147","journal-title":"Am J Psychiatry"},{"issue":"8","key":"1567_CR3","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1002\/eat.22927","volume":"51","author":"JM Nagata","year":"2018","unstructured":"Nagata JM et al (2018) Disordered eating behaviors and cardiometabolic risk among young adults with overweight or obesity. Int J Eat Disord 51(8):931\u2013941. https:\/\/doi.org\/10.1002\/eat.22927","journal-title":"Int J Eat Disord"},{"issue":"12","key":"1567_CR4","doi-asserted-by":"publisher","first-page":"904","DOI":"10.4082\/kjfm.2010.31.12.904","volume":"31","author":"Y Ko","year":"2010","unstructured":"Ko Y et al (2010) Maximum meal calorie variation and cardiovascular risk factors. Korean J Fam Med 31(12):904\u2013912. https:\/\/doi.org\/10.4082\/kjfm.2010.31.12.904","journal-title":"Korean J Fam Med"},{"issue":"12","key":"1567_CR5","doi-asserted-by":"publisher","first-page":"1901","DOI":"10.1002\/eat.23404","volume":"53","author":"EK Presseller","year":"2020","unstructured":"Presseller EK et al (2020) The application of continuous glucose monitoring technology to eating disorders research: An idea worth researching. Int J Eat Disord 53(12):1901\u20131905. https:\/\/doi.org\/10.1002\/eat.23404","journal-title":"Int J Eat Disord"},{"issue":"8","key":"1567_CR6","doi-asserted-by":"publisher","first-page":"1366","DOI":"10.1007\/s00125-019-4901-6","volume":"62","author":"MP Bancks","year":"2019","unstructured":"Bancks MP et al (2019) Fasting glucose variability in young adulthood and incident diabetes, cardiovascular disease and all-cause mortality. Diabetologia 62(8):1366\u20131374. https:\/\/doi.org\/10.1007\/s00125-019-4901-6","journal-title":"Diabetologia"},{"issue":"14","key":"1567_CR7","doi-asserted-by":"publisher","first-page":"1853","DOI":"10.2169\/internalmedicine.55.5632","volume":"55","author":"Y Nakai","year":"2016","unstructured":"Nakai Y et al (2016) Serum lipid levels in patients with eating disorders. Intern Med 55(14):1853\u20131857. https:\/\/doi.org\/10.2169\/internalmedicine.55.5632","journal-title":"Intern Med"},{"issue":"1","key":"1567_CR8","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1002\/eat.23004","volume":"52","author":"T Udo","year":"2019","unstructured":"Udo T, Grilo CM (2019) Psychiatric and medical correlates of DSM-5 eating disorders in a nationally representative sample of adults in the United States. Int J Eat Disord 52(1):42\u201350. https:\/\/doi.org\/10.1002\/eat.23004","journal-title":"Int J Eat Disord"},{"issue":"3","key":"1567_CR9","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.psychres.2004.06.019","volume":"134","author":"P Monteleone","year":"2005","unstructured":"Monteleone P et al (2005) Enhanced serum cholesterol and triglyceride levels in bulimia nervosa: relationships to psychiatric comorbidity, psychopathology and hormonal variables. Psychiatry Res 134(3):267\u2013273. https:\/\/doi.org\/10.1016\/j.psychres.2004.06.019","journal-title":"Psychiatry Res"},{"issue":"6","key":"1567_CR10","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1002\/eat.22334","volume":"48","author":"A Raevuori","year":"2015","unstructured":"Raevuori A et al (2015) Highly increased risk of type 2 diabetes in patients with binge eating disorder and bulimia nervosa. Int J Eat Disord 48(6):555\u2013562. https:\/\/doi.org\/10.1002\/eat.22334","journal-title":"Int J Eat Disord"},{"issue":"1","key":"1567_CR11","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1007\/s40519-016-0313-5","volume":"22","author":"P Olguin","year":"2017","unstructured":"Olguin P et al (2017) Medical comorbidity of binge eating disorder. Eat Weight Disord 22(1):13\u201326. https:\/\/doi.org\/10.1007\/s40519-016-0313-5","journal-title":"Eat Weight Disord"},{"issue":"1","key":"1567_CR12","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1002\/eat.22624","volume":"50","author":"LM Thornton","year":"2017","unstructured":"Thornton LM et al (2017) Binge-eating disorder in the Swedish national registers: Somatic comorbidity. Int J Eat Disord 50(1):58\u201365. https:\/\/doi.org\/10.1002\/eat.22624","journal-title":"Int J Eat Disord"},{"issue":"12","key":"1567_CR13","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1007\/s11892-017-0949-1","volume":"17","author":"R Nieto-Mart\u00ednez","year":"2017","unstructured":"Nieto-Mart\u00ednez R et al (2017) Are eating disorders risk factors for type 2 diabetes? A systematic review and meta-analysis. Curr DiabRep 17(12):138. https:\/\/doi.org\/10.1007\/s11892-017-0949-1","journal-title":"Curr DiabRep"},{"issue":"1","key":"1567_CR14","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1001\/jamapsychiatry.2019.2914","volume":"77","author":"RM Tith","year":"2020","unstructured":"Tith RM et al (2020) Association of bulimia nervosa with long-term risk of cardiovascular disease and mortality among women. JAMA Psychiat 77(1):44\u201351. https:\/\/doi.org\/10.1001\/jamapsychiatry.2019.2914","journal-title":"JAMA Psychiat"},{"issue":"4","key":"1567_CR15","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1002\/eat.10047","volume":"31","author":"MD Zwaan","year":"2002","unstructured":"Zwaan MD, Aslam Z, Mitchell JE (2002) Research on energy expenditure in individuals with eating disorders: a review. Int J Eating Disord 31(4):361\u2013369","journal-title":"Int J Eating Disord"},{"issue":"4","key":"1567_CR16","doi-asserted-by":"publisher","first-page":"807","DOI":"10.3945\/ajcn.115.109173","volume":"102","author":"MJ M\u00fcller","year":"2015","unstructured":"M\u00fcller MJ et al (2015) Metabolic adaptation to caloric restriction and subsequent refeeding: the Minnesota Starvation Experiment revisited. Am J Clin Nutr 102(4):807\u2013819. https:\/\/doi.org\/10.3945\/ajcn.115.109173","journal-title":"Am J Clin Nutr"},{"key":"1567_CR17","doi-asserted-by":"publisher","first-page":"110875","DOI":"10.1016\/j.exger.2020.110875","volume":"133","author":"J Most","year":"2020","unstructured":"Most J, Redman LM (2020) Impact of calorie restriction on energy metabolism in humans. Exp Gerontol 133:110875. https:\/\/doi.org\/10.1016\/j.exger.2020.110875","journal-title":"Exp Gerontol"},{"key":"1567_CR18","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.clnesp.2017.09.003","volume":"22","author":"TF Mathisen","year":"2017","unstructured":"Mathisen TF et al (2017) Evaluation of a short protocol for indirect calorimetry in females with eating disorders and healthy controls. Clinical Nutrition ESPEN 22:28\u201335. https:\/\/doi.org\/10.1016\/j.clnesp.2017.09.003","journal-title":"Clinical Nutrition ESPEN"},{"issue":"2","key":"1567_CR19","doi-asserted-by":"publisher","first-page":"S49","DOI":"10.1016\/j.jadohealth.2009.11.119","volume":"46","author":"D Aschettino-Manevitz","year":"2010","unstructured":"Aschettino-Manevitz D et al (2010) Triiodothyronine (T3) and metabolic rate in adolescents with eating disorders: is there a correlation? J Adolesc Health 46(2):S49\u2013S50. https:\/\/doi.org\/10.1016\/j.jadohealth.2009.11.119","journal-title":"J Adolesc Health"},{"issue":"9","key":"1567_CR20","doi-asserted-by":"publisher","first-page":"1460","DOI":"10.1002\/eat.23301","volume":"53","author":"B Kochavi","year":"2020","unstructured":"Kochavi B et al (2020) Resting energy expenditure in acutely ill and stabilized patients with anorexia nervosa and bulimia nervosa. Int J Eat Disord 53(9):1460\u20131468. https:\/\/doi.org\/10.1002\/eat.23301","journal-title":"Int J Eat Disord"},{"issue":"2","key":"1567_CR21","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1001\/archpsyc.1990.01810140044007","volume":"47","author":"MJ Devlin","year":"1990","unstructured":"Devlin MJ et al (1990) Metabolic abnormalities in bulimia nervosa. Arch Gen Psychiatry 47(2):144\u2013148","journal-title":"Arch Gen Psychiatry"},{"issue":"9","key":"1567_CR22","doi-asserted-by":"publisher","first-page":"191","DOI":"10.3390\/metabo9090191","volume":"9","author":"DL Santos Ferreira","year":"2019","unstructured":"Santos Ferreira DL et al (2019) Associations between blood metabolic profile at 7 years old and eating disorders in adolescence: findings from the avon longitudinal study of parents and children. Metabolites 9(9):191. https:\/\/doi.org\/10.3390\/metabo9090191","journal-title":"Metabolites"},{"issue":"12","key":"1567_CR23","doi-asserted-by":"publisher","first-page":"1887","DOI":"10.3390\/nu10121887","volume":"10","author":"TF Mathisen","year":"2018","unstructured":"Mathisen TF et al (2018) Managing risk of non-communicable diseases in women with bulimia nervosa or binge eating disorders: a randomized trial with 12 months follow-up. Nutrients 10(12):1887. https:\/\/doi.org\/10.3390\/nu10121887","journal-title":"Nutrients"},{"issue":"4","key":"1567_CR24","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1210\/endrev\/bnaa016","volume":"41","author":"MCK Severinsen","year":"2020","unstructured":"Severinsen MCK, Pedersen BK (2020) Muscle-organ crosstalk: the emerging roles of myokines. Endocr Rev 41(4):594\u2013609. https:\/\/doi.org\/10.1210\/endrev\/bnaa016","journal-title":"Endocr Rev"},{"key":"1567_CR25","doi-asserted-by":"publisher","first-page":"3756750","DOI":"10.1155\/2019\/3756750","volume":"2019","author":"D Tian","year":"2019","unstructured":"Tian D, Meng J (2019) Exercise for prevention and relief of cardiovascular disease: prognoses, mechanisms, and approaches. Oxid Med Cell Longev 2019:3756750. https:\/\/doi.org\/10.1155\/2019\/3756750","journal-title":"Oxid Med Cell Longev"},{"key":"1567_CR26","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2021-104827","author":"J Tarp","year":"2021","unstructured":"Tarp J et al (2021) Device-measured physical activity, adiposity and mortality: a harmonised meta-analysis of eight prospective cohort studies. Br J Sports Med. https:\/\/doi.org\/10.1136\/bjsports-2021-104827","journal-title":"Br J Sports Med"},{"issue":"1","key":"1567_CR27","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1186\/s40337-018-0215-1","volume":"6","author":"TF Mathisen","year":"2018","unstructured":"Mathisen TF et al (2018) Treatment effects on compulsive exercise and physical activity in eating disorders. J Eat Disord 6(1):43. https:\/\/doi.org\/10.1186\/s40337-018-0215-1","journal-title":"J Eat Disord"},{"issue":"11 Suppl","key":"1567_CR28","doi-asserted-by":"publisher","first-page":"S512","DOI":"10.1249\/01.mss.0000185659.11982.3d","volume":"37","author":"CE Matthew","year":"2005","unstructured":"Matthew CE (2005) Calibration of accelerometer output for adults. Med Sci Sports Exerc 37(11 Suppl):S512\u2013S522","journal-title":"Med Sci Sports Exerc"},{"issue":"4","key":"1567_CR29","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1002\/eat.23228","volume":"53","author":"TF Mathisen","year":"2020","unstructured":"Mathisen TF et al (2020) Is physical exercise and dietary therapy a feasible alternative to cognitive behavior therapy in treatment of eating disorders? A randomized controlled trial of two group therapies. Int J Eat Disord 53(4):574\u2013585. https:\/\/doi.org\/10.1002\/eat.23228","journal-title":"Int J Eat Disord"},{"issue":"1","key":"1567_CR30","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1186\/s12888-017-1312-4","volume":"17","author":"TF Mathisen","year":"2017","unstructured":"Mathisen TF et al (2017) The PED-t trial protocol: The effect of physical exercise -and dietary therapy compared with cognitive behavior therapy in treatment of bulimia nervosa and binge eating disorder. BMC Psychiatry 17(1):180. https:\/\/doi.org\/10.1186\/s12888-017-1312-4","journal-title":"BMC Psychiatry"},{"issue":"5","key":"1567_CR31","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1002\/erv.2372","volume":"23","author":"\u00d8 R\u00f8","year":"2015","unstructured":"R\u00f8 \u00d8, Reas DL, Stedal K (2015) Eating Disorder Examination Questionnaire (EDE-Q) in Norwegian adults: discrimination between female controls and eating disorder patients. Eur Eat Disord Rev 23(5):408\u2013412. https:\/\/doi.org\/10.1002\/erv.2372","journal-title":"Eur Eat Disord Rev"},{"issue":"4","key":"1567_CR32","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1515\/cclm-2019-1253","volume":"58","author":"MR Langlois","year":"2020","unstructured":"Langlois MR et al (2020) Quantifying atherogenic lipoproteins for lipid-lowering strategies: consensus-based recommendations from EAS and EFLM. Clin Chem Lab Med 58(4):496\u2013517. https:\/\/doi.org\/10.1515\/cclm-2019-1253","journal-title":"Clin Chem Lab Med"},{"key":"1567_CR33","unstructured":"F\u00fcrst Medical Laboratory, Function of Thyroidea. 2021, F\u00fcrst Medical Laboratory: Furst no."},{"issue":"5","key":"1567_CR34","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1530\/eje.0.1430639","volume":"143","author":"T Bjoro","year":"2000","unstructured":"Bjoro T et al (2000) Prevalence of thyroid disease, thyroid dysfunction and thyroid peroxidase antibodies in a large, unselected population The Health Study of Nord-Trondelag (HUNT). Eur J Endocrinol 143(5):639\u2013647. https:\/\/doi.org\/10.1530\/eje.0.1430639","journal-title":"Eur J Endocrinol"},{"key":"1567_CR35","volume-title":"Statistical power analysis for the behavioral sciences","author":"J Cohen","year":"1988","unstructured":"Cohen J (1988) Statistical power analysis for the behavioral sciences. Lawrence Erlbaum, Hillsdale"},{"issue":"1","key":"1567_CR36","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1186\/1471-2288-14-49","volume":"14","author":"BE Egbewale","year":"2014","unstructured":"Egbewale BE, Lewis M, Sim J (2014) Bias, precision and statistical power of analysis of covariance in the analysis of randomized trials with baseline imbalance: a simulation study. BMC Med Res Methodol 14(1):49","journal-title":"BMC Med Res Methodol"},{"issue":"1","key":"1567_CR37","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/s0031-9384(02)00829-6","volume":"77","author":"KA Gendall","year":"2002","unstructured":"Gendall KA et al (2002) The effect of bulimia nervosa on plasma glucose and lipids. Physiol Behav 77(1):99\u2013105. https:\/\/doi.org\/10.1016\/s0031-9384(02)00829-6","journal-title":"Physiol Behav"},{"issue":"1","key":"1567_CR38","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1186\/s12888-022-04005-y","volume":"22","author":"P Hay","year":"2022","unstructured":"Hay P et al (2022) Physical and mental health outcomes of an integrated cognitive behavioural and weight management therapy for people with an eating disorder characterized by binge eating and a high body mass index: a randomized controlled trial. BMC Psychiatry 22(1):355. https:\/\/doi.org\/10.1186\/s12888-022-04005-y","journal-title":"BMC Psychiatry"},{"issue":"4","key":"1567_CR39","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1002\/eat.22841","volume":"51","author":"TF Mathisen","year":"2018","unstructured":"Mathisen TF et al (2018) Body composition and physical fitness in women with bulimia nervosa or binge-eating disorder. Int J Eat Disord 51(4):11. https:\/\/doi.org\/10.1002\/eat.22841","journal-title":"Int J Eat Disord"},{"issue":"4","key":"1567_CR40","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1177\/1932296815577424","volume":"9","author":"H Sasai","year":"2015","unstructured":"Sasai H et al (2015) Does visceral fat estimated by dual-energy X-ray absorptiometry independently predict cardiometabolic risks in adults? J Diabetes Sci Technol 9(4):917\u2013924. https:\/\/doi.org\/10.1177\/1932296815577424","journal-title":"J Diabetes Sci Technol"},{"issue":"3","key":"1567_CR41","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1034\/j.1600-0447.2003.00117.x","volume":"108","author":"KA Gendall","year":"2003","unstructured":"Gendall KA et al (2003) Thyroid indices and treatment outcome in bulimia nervosa. Acta Psychiatr Scand 108(3):190\u2013195. https:\/\/doi.org\/10.1034\/j.1600-0447.2003.00117.x","journal-title":"Acta Psychiatr Scand"},{"issue":"4","key":"1567_CR42","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1159\/000087923","volume":"81","author":"A Troisi","year":"2005","unstructured":"Troisi A et al (2005) Plasma ghrelin in anorexia, bulimia, and binge-eating disorder: relations with eating patterns and circulating concentrations of cortisol and thyroid hormones. Neuroendocrinology 81(4):259\u2013266. https:\/\/doi.org\/10.1159\/000087923","journal-title":"Neuroendocrinology"},{"issue":"5","key":"1567_CR43","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1530\/eje-13-0459","volume":"169","author":"BO Asvold","year":"2013","unstructured":"Asvold BO, Vatten LJ, Bj\u00f8ro T (2013) Changes in the prevalence of hypothyroidism: the HUNT Study in Norway. Eur J Endocrinol 169(5):613\u2013620. https:\/\/doi.org\/10.1530\/eje-13-0459","journal-title":"Eur J Endocrinol"},{"issue":"2","key":"1567_CR44","doi-asserted-by":"publisher","first-page":"345","DOI":"10.23736\/s0022-4707.22.14103-4","volume":"63","author":"K Hejazi","year":"2023","unstructured":"Hejazi K, Wong A (2023) Effects of exercise training on inflammatory and cardiometabolic health markers in overweight and obese adults: a systematic review and meta-analysis of randomized controlled trials. J Sports Med Phys Fitness 63(2):345\u2013359. https:\/\/doi.org\/10.23736\/s0022-4707.22.14103-4","journal-title":"J Sports Med Phys Fitness"},{"key":"1567_CR45","unstructured":"Norwegian Institute of Public Health, University of Troms\u00f8, and Norwegian University of Science and Technology, Total cholesterol level (Indicator 17), In: Indicators for non-communicable diseases. 2018, Norwegian Institute of Public Health FHI.no."},{"key":"1567_CR46","unstructured":"Korsvold A. Change in eating behavior and eating pattern during treatment of Bulimia Nervosa and Binge Eating Disorder\u2014a randomized, clinical trial comparing effects from cognitive behavioral therapy, and a combination of physical exercise and dietary therapy, In: Department of Nutrition, Faculty of Medicine, University of Oslo: University of Oslo Library. 2017, p. 95."},{"issue":"5","key":"1567_CR47","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1001\/jamapsychiatry.2019.4188","volume":"77","author":"S Bahrami","year":"2020","unstructured":"Bahrami S et al (2020) Shared genetic loci between body mass index and major psychiatric disorders: a genome-wide association study. JAMA Psychiat 77(5):503\u2013512. https:\/\/doi.org\/10.1001\/jamapsychiatry.2019.4188","journal-title":"JAMA Psychiat"},{"issue":"7","key":"1567_CR48","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1080\/15592294.2019.1614416","volume":"14","author":"M Jacques","year":"2019","unstructured":"Jacques M et al (2019) Epigenetic changes in healthy human skeletal muscle following exercise- a systematic review. Epigenetics 14(7):633\u2013648. https:\/\/doi.org\/10.1080\/15592294.2019.1614416","journal-title":"Epigenetics"}],"container-title":["Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40519-023-01567-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40519-023-01567-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40519-023-01567-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T15:40:42Z","timestamp":1682610042000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40519-023-01567-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,27]]},"references-count":48,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["1567"],"URL":"https:\/\/doi.org\/10.1007\/s40519-023-01567-y","relation":{},"ISSN":["1590-1262"],"issn-type":[{"value":"1590-1262","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,27]]},"assertion":[{"value":"20 September 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 April 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 April 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no conflict to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"This trial was prospectively registered in Norwegian Regional Committee for Medical and Health Research Ethics on December 16, 2013, with the identifier number 2013\/1871, and in Clinical Trials on February 17, 2014 with the identifier number NCT02079935.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All participants signed an informed\nconsent before participation in the original trial.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}],"article-number":"41"}}