{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T16:21:46Z","timestamp":1789575706293,"version":"build-2803163510"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Aging Clin Exp Res"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1007\/s40520-018-1046-2","type":"journal-article","created":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T14:01:18Z","timestamp":1538402478000},"page":"969-975","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Fall-risk increasing drugs and prevalence of polypharmacy in older patients discharged from an Orthogeriatric Unit after a hip fracture"],"prefix":"10.1007","volume":"31","author":[{"given":"Andrea","family":"Correa-P\u00e9rez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Delgado-Silveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sagrario","family":"Mart\u00edn-Arag\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurora M.","family":"Rojo-Sanch\u00eds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso J.","family":"Cruz-Jentoft","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,10,1]]},"reference":[{"key":"1046_CR1","doi-asserted-by":"publisher","first-page":"1214","DOI":"10.1111\/j.1532-5415.1995.tb07396.x","volume":"43","author":"ME Tinetti","year":"1995","unstructured":"Tinetti ME, Doucette J, Claus E et al (1995) Risk factors for serious injury during falls by older persons in the community. J Am Geriatr Soc 43:1214\u20131221","journal-title":"J Am Geriatr Soc"},{"key":"1046_CR2","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1017\/S071498081000070X","volume":"30","author":"NM Peel","year":"2011","unstructured":"Peel NM (2011) Epidemiology of falls in older age. Can J Aging 30:7\u201319. https:\/\/doi.org\/10.1017\/S071498081000070X","journal-title":"Can J Aging"},{"key":"1046_CR3","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1093\/ptj\/85.7.648","volume":"85","author":"A Shumway-Cook","year":"2005","unstructured":"Shumway-Cook A, Ciol MA, Gruber W et al (2005) Incidence of and risk factors for falls following hip fracture in community-dwelling older adults. Phys Ther 85:648\u2013655","journal-title":"Phys Ther"},{"key":"1046_CR4","doi-asserted-by":"publisher","first-page":"1464","DOI":"10.1111\/jgs.12412","volume":"61","author":"C Sj\u00f6berg","year":"2013","unstructured":"Sj\u00f6berg C, Wallerstedt SM (2013) Effects of medication reviews performed by a physician on treatment with fracture-preventing and fall-risk-increasing drugs in older adults with hip fracture-a randomized controlled study. J Am Geriatr Soc 61:1464\u20131472. https:\/\/doi.org\/10.1111\/jgs.12412","journal-title":"J Am Geriatr Soc"},{"key":"1046_CR5","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1007\/s00776-015-0715-7","volume":"20","author":"H Ikutomo","year":"2015","unstructured":"Ikutomo H, Nagai K, Nakagawa N et al (2015) Falls in patients after total hip arthroplasty in Japan. J Orthop Sci 20:663\u2013668. https:\/\/doi.org\/10.1007\/s00776-015-0715-7","journal-title":"J Orthop Sci"},{"key":"1046_CR6","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1093\/gerona\/glp003","volume":"64A","author":"BD Lloyd","year":"2009","unstructured":"Lloyd BD, Williamson DA, Singh NA et al (2009) Recurrent and Injurious Falls in the Year Following Hip Fracture: A Prospective Study of Incidence and Risk Factors From the Sarcopenia and Hip Fracture Study. J Gerontol Ser A Biol Sci Med Sci 64A:599\u2013609. https:\/\/doi.org\/10.1093\/gerona\/glp003","journal-title":"J Gerontol Ser A Biol Sci Med Sci"},{"key":"1046_CR7","doi-asserted-by":"publisher","first-page":"653","DOI":"10.2165\/11538200-000000000-00000","volume":"27","author":"C Sj\u00f6berg","year":"2010","unstructured":"Sj\u00f6berg C, Bladh L, Klintberg L et al (2010) Treatment with fall-risk-increasing and fracture-preventing drugs before and after a hip fracture: an observational study. Drugs Aging 27:653\u2013661. https:\/\/doi.org\/10.2165\/11538200-000000000-00000","journal-title":"Drugs Aging"},{"key":"1046_CR8","doi-asserted-by":"publisher","first-page":"437","DOI":"10.2147\/TCRM.S63756","volume":"10","author":"Y Chen","year":"2014","unstructured":"Chen Y, Zhu LL, Zhou Q (2014) Effects of drug pharmacokinetic\/pharmacodynamic properties, characteristics of medication use, and relevant pharmacological interventions on fall risk in elderly patients. Ther Clin Risk Manag 10:437\u2013448. https:\/\/doi.org\/10.2147\/TCRM.S63756","journal-title":"Ther Clin Risk Manag"},{"key":"1046_CR9","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1111\/j.1532-5415.1999.tb01898.x","volume":"47","author":"RM Leipzig","year":"1999","unstructured":"Leipzig RM, Cumming RG, Tinetti ME (1999) Drugs and falls in older people: a systematic review and meta-analysis: I. Psychotropic drugs. J Am Geriatr Soc 47:30\u201339. https:\/\/doi.org\/10.1111\/j.1532-5415.1999.tb01898.x","journal-title":"J Am Geriatr Soc"},{"key":"1046_CR10","doi-asserted-by":"publisher","first-page":"1952","DOI":"10.1001\/archinternmed.2009.357","volume":"169","author":"JC Woolcott","year":"2009","unstructured":"Woolcott JC, Richardson KJ, Wiens MO et al (2009) Meta-analysis of the impact of 9 medication classes on falls in elderly persons. Arch Intern Med 169:1952\u20131960. https:\/\/doi.org\/10.1001\/archinternmed.2009.357","journal-title":"Arch Intern Med"},{"key":"1046_CR11","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1111\/j.1365-2125.2005.02543.x","volume":"61","author":"G Ziere","year":"2006","unstructured":"Ziere G, Dieleman JP, Hofman A et al (2006) Polypharmacy and falls in the middle age and elderly population. Br J Clin Pharmacol 61:218\u2013223. https:\/\/doi.org\/10.1111\/j.1365-2125.2005.02543.x","journal-title":"Br J Clin Pharmacol"},{"key":"1046_CR12","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1186\/1471-2318-14-92","volume":"14","author":"B Helgad\u00f3ttir","year":"2014","unstructured":"Helgad\u00f3ttir B, Laflamme L, Mon\u00e1rrez-Espino J et al (2014) Medication and fall injury in the elderly population; do individual demographics, health status and lifestyle matter? BMC Geriatr 14:92. https:\/\/doi.org\/10.1186\/1471-2318-14-92","journal-title":"BMC Geriatr"},{"key":"1046_CR13","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1111\/j.1365-2125.2006.02736.x","volume":"63","author":"N Velde van der","year":"2007","unstructured":"van der Velde N, Stricker BHC, Pols HAP et al (2007) Risk of falls after withdrawal of fall-risk-increasing drugs: a prospective cohort study. Br J Clin Pharmacol 63:232\u2013237. https:\/\/doi.org\/10.1111\/j.1365-2125.2006.02736.x","journal-title":"Br J Clin Pharmacol"},{"key":"1046_CR14","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1111\/j.1532-5415.1999.tb01899.x","volume":"47","author":"RM Leipzig","year":"1999","unstructured":"Leipzig RM, Cumming RG, Tinetti ME (1999) Drugs and falls in older people: a systematic review and meta-analysis: II. Cardiac and analgesic drugs. J Am Geriatr Soc 47:40\u201350","journal-title":"J Am Geriatr Soc"},{"key":"1046_CR15","unstructured":"The Swedish National Board of Health and Welfare (2010) Indikatorer f\u00f6r god l\u00e4kemedelsterapi hos \u00e4ldre. [Indicators for appropriate drug therapy in the elderly]. https:\/\/www.socialstyrelsen.se\/publikationer2010\/2010-6-29 . https:\/\/www.socialstyrelsen.se\/Lists\/Artikelkatalog\/Attachments\/18085\/2010-6-29.pdf"},{"key":"1046_CR16","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1186\/1471-2318-14-40","volume":"14","author":"V Milos","year":"2014","unstructured":"Milos V, Bondesson \u00c5, Magnusson M et al (2014) Fall risk-increasing drugs and falls: a cross-sectional study among elderly patients in primary care. BMC Geriatr 14:40. https:\/\/doi.org\/10.1186\/1471-2318-14-40","journal-title":"BMC Geriatr"},{"key":"1046_CR17","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1186\/1756-0500-5-355","volume":"5","author":"I Saltvedt","year":"2012","unstructured":"Saltvedt I, Prestmo A, Einarsen E et al (2012) Development and delivery of patient treatment in the trondheim hip fracture trial. A new geriatric in-hospital pathway for elderly patients with hip fracture. BMC Res Notes 5:355. https:\/\/doi.org\/10.1186\/1756-0500-5-355","journal-title":"BMC Res Notes"},{"key":"1046_CR18","doi-asserted-by":"publisher","first-page":"e49","DOI":"10.1097\/BOT.0b013e3182a5a045","volume":"28","author":"KV Grigoryan","year":"2014","unstructured":"Grigoryan KV, Javedan H, Rudolph JL (2014) Orthogeriatric care models and outcomes in hip fracture patients: a systematic review and meta-analysis. J Orthop Trauma 28:e49\u2013e55. https:\/\/doi.org\/10.1097\/BOT.0b013e3182a5a045","journal-title":"J Orthop Trauma"},{"key":"1046_CR19","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1007\/s12603-018-1007-7","volume":"22","author":"AM Sanford","year":"2018","unstructured":"Sanford AM, Morley JE, McKee A (2018) Editorial: orthogeriatrics and hip fractures. J Nutr Health Aging 22:457\u2013462. https:\/\/doi.org\/10.1007\/s12603-018-1007-7","journal-title":"J Nutr Health Aging"},{"key":"1046_CR20","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1093\/ptj\/64.1.35","volume":"64","author":"MK Holden","year":"1984","unstructured":"Holden MK, Gill KM, Magliozzi MR et al (1984) Clinical gait assessment in the neurologically impaired reliability and meaningfulness. Phys Ther 64:35\u201340. https:\/\/doi.org\/10.1093\/ptj\/64.1.35","journal-title":"Phys Ther"},{"key":"1046_CR21","unstructured":"Scotland N (2015) Polypharmacy Guidance for the safe and effective use of multiple medicines to manage long term conditions. http:\/\/www.jitscotland.org.uk\/resource\/polypharmacy-guidance-march-2015\/ . Accessed 1 May 2016"},{"key":"1046_CR22","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1186\/2193-1801-3-483","volume":"3","author":"K Heckenbach","year":"2014","unstructured":"Heckenbach K, Ostermann T, Schad F et al (2014) Medication and falls in elderly outpatients: an epidemiological study from a german pharmacovigilance network. Springerplus 3:483. https:\/\/doi.org\/10.1186\/2193-1801-3-483","journal-title":"Springerplus"},{"key":"1046_CR23","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1093\/ageing\/afu145","volume":"44","author":"D O\u2019mahony","year":"2015","unstructured":"O\u2019mahony D, O\u2019sullivan D, Byrne S et al (2015) STOPP\/START criteria for potentially inappropriate prescribing in older people: version 2. Age Ageing 44:213\u2013218. https:\/\/doi.org\/10.1093\/ageing\/afu145","journal-title":"Age Ageing"},{"key":"1046_CR24","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1093\/ageing\/afw161","volume":"46","author":"NDA Boy\u00e9","year":"2017","unstructured":"Boy\u00e9 NDA, van der Velde N, de Vries OJ et al (2017) Effectiveness of medication withdrawal in older fallers: Results from the improving medication prescribing to reduce risk of falls (IMPROveFALL) trial. Age Ageing 46:142\u2013146. https:\/\/doi.org\/10.1093\/ageing\/afw161","journal-title":"Age Ageing"},{"key":"1046_CR25","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1007\/s40266-013-0151-3","volume":"31","author":"A Bennett","year":"2014","unstructured":"Bennett A, Gnjidic D, Gillett M et al (2014) Prevalence and impact of fall-risk-increasing drugs, polypharmacy, and drug\u2013drug interactions in robust versus frail hospitalised falls patients: a prospective cohort study. Drugs Aging 31:225\u2013232. https:\/\/doi.org\/10.1007\/s40266-013-0151-3","journal-title":"Drugs Aging"},{"key":"1046_CR26","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1111\/j.1532-5415.2011.03372.x","volume":"59","author":"A Kragh","year":"2011","unstructured":"Kragh A, Elmst\u00e5hl S, Atroshi I (2011) Older adults\u2019 medication use 6\u00a0months before and after hip fracture: a population-based cohort study. J Am Geriatr Soc 59:863\u2013868. https:\/\/doi.org\/10.1111\/j.1532-5415.2011.03372.x","journal-title":"J Am Geriatr Soc"},{"key":"1046_CR27","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1001\/jamainternmed.2016.4814","volume":"176","author":"JC Munson","year":"2016","unstructured":"Munson JC, Bynum JPW, Bell J et al (2016) Patterns of prescription drug use before and after fragility fracture. JAMA Intern Med 176:1531\u20131538. https:\/\/doi.org\/10.1001\/jamainternmed.2016.4814","journal-title":"JAMA Intern Med"},{"key":"1046_CR28","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1007\/s40266-014-0184-2","volume":"31","author":"M Rossini","year":"2014","unstructured":"Rossini M, Viapiana O, Adami S et al (2014) Medication use before and after hip fracture: a population-based cohort and case-control study. Drugs Aging 31:547\u2013553. https:\/\/doi.org\/10.1007\/s40266-014-0184-2","journal-title":"Drugs Aging"},{"key":"1046_CR29","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1136\/postgradmedj-2017-135129","volume":"94","author":"M Beunza-Sola","year":"2018","unstructured":"Beunza-Sola M, Hidalgo-Ovejero \u00c1M, Mart\u00ed-Ayerdi J et al (2018) Study of fall risk-increasing drugs in elderly patients before and after a bone fracture. Postgrad Med J 94:76\u201380. https:\/\/doi.org\/10.1136\/postgradmedj-2017-135129","journal-title":"Postgrad Med J"},{"key":"1046_CR30","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1111\/jep.12624","volume":"23","author":"JP Turner","year":"2017","unstructured":"Turner JP, Tervonen HE, Shakib S et al (2017) Factors associated with use of falls risk-increasing drugs among patients of a geriatric oncology outpatient clinic in Australia: a cross-sectional study. J Eval Clin Pract 23:361\u2013368. https:\/\/doi.org\/10.1111\/jep.12624","journal-title":"J Eval Clin Pract"},{"key":"1046_CR31","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1186\/s12875-018-0795-5","volume":"19","author":"A Rieckert","year":"2018","unstructured":"Rieckert A, Trampisch US, Klaa\u00dfen-Mielke R et al (2018) Polypharmacy in older patients with chronic diseases: a cross-sectional analysis of factors associated with excessive polypharmacy. BMC Fam Pract 19:113. https:\/\/doi.org\/10.1186\/s12875-018-0795-5","journal-title":"BMC Fam Pract"},{"key":"1046_CR32","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1007\/s00228-014-1792-9","volume":"71","author":"B Belfrage","year":"2015","unstructured":"Belfrage B, Koldestam A, Sj\u00f6berg C et al (2015) Number of drugs in the medication list as an indicator of prescribing quality: a validation study of polypharmacy indicators in older hip fracture patients. Eur J Clin Pharmacol 71:363\u2013368. https:\/\/doi.org\/10.1007\/s00228-014-1792-9","journal-title":"Eur J Clin Pharmacol"},{"key":"1046_CR33","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1046\/j.1532-5415.2001.49115.x","volume":"49","author":"American Geriatrics Society, British Geriatrics Society and AA of OSP on FP","year":"2001","unstructured":"American Geriatrics Society, British Geriatrics Society and AA of OSP on FP (2001) Guideline for the Prevention of Falls in Older Persons. J Am Geriatr Soc 49:664\u2013672. https:\/\/doi.org\/10.1046\/j.1532-5415.2001.49115.x","journal-title":"J Am Geriatr Soc"}],"container-title":["Aging Clinical and Experimental Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s40520-018-1046-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s40520-018-1046-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s40520-018-1046-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T19:03:19Z","timestamp":1605121399000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s40520-018-1046-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,1]]},"references-count":33,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["1046"],"URL":"https:\/\/doi.org\/10.1007\/s40520-018-1046-2","relation":{},"ISSN":["1720-8319"],"issn-type":[{"value":"1720-8319","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,1]]},"assertion":[{"value":"25 June 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 September 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 October 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Authors declare no competing interests. All authors have completed the Conflict of Interest Disclosure form and declare: no support from any organisation for the submitted work; no financial relationships with any organisations that might have an interest in the submitted work in the previous 3\u00a0years; no other relationships or activities that could appear to have influenced the submitted work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was approved by the Ethics Committee on Clinical Research of the Hospital Universitario Ram\u00f3n y Cajal (Madrid) on May 2016.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statement of human and animal rights"}},{"value":"No consent forms from patients were requested, as this is a retrospective study and hospital-collected data were analysed. Patients accept such kind of use of data when they are admitted to the hospital.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}