{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T15:11:44Z","timestamp":1783350704638,"version":"3.54.6"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T00:00:00Z","timestamp":1603929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T00:00:00Z","timestamp":1603929600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Aging Clin Exp Res"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1007\/s40520-020-01738-2","type":"journal-article","created":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T19:02:35Z","timestamp":1603998155000},"page":"1619-1625","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The qSOFA score combined with the initial red cell distribution width as a useful predictor of 30\u00a0day mortality among older adults with infection in an emergency department"],"prefix":"10.1007","volume":"33","author":[{"given":"Sang Yun","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8914-1640","authenticated-orcid":false,"given":"Seon Hee","family":"Woo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woon Jeong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dae Hee","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Hwan","family":"Seol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"June Young","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sikyoung","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanghyun","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyungman","family":"Cha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun Song","family":"Youn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,10,29]]},"reference":[{"key":"1738_CR1","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1097\/01.CCM.0000194535.82812.BA","volume":"34","author":"GS Martin","year":"2006","unstructured":"Martin GS, Mannino DM, Moss M (2006) The effect of age on the development and outcome of adult sepsis. Crit Care Med 34:15\u201321","journal-title":"Crit Care Med"},{"key":"1738_CR2","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1177\/0885066610397116","volume":"27","author":"P Nasa","year":"2012","unstructured":"Nasa P, Juneja D, Singh O et al (2012) Severe sepsis and its impact on outcome in elderly and very elderly patients admitted in intensive care unit. J Intensive Care Med 27:179\u2013183","journal-title":"J Intensive Care Med"},{"key":"1738_CR3","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1093\/ageing\/afi037","volume":"34","author":"S Vosylius","year":"2005","unstructured":"Vosylius S, Sipylaite J, Ivaskevicius J (2005) Determinants of outcome in elderly patients admitted to the intensive care unit. Age Ageing 34:157\u2013162","journal-title":"Age Ageing"},{"key":"1738_CR4","doi-asserted-by":"publisher","first-page":"1379","DOI":"10.1046\/j.1532-5415.2001.49270.x","volume":"49","author":"LC Mion","year":"2001","unstructured":"Mion LC, Palmer RM, Anetzberger GJ et al (2001) Establishing a case-finding and referral system for at-risk older individuals in the emergency department setting: the SIGNET model. J Am Geriatr Soc 49:1379\u20131386","journal-title":"J Am Geriatr Soc"},{"key":"1738_CR5","doi-asserted-by":"publisher","first-page":"20","DOI":"10.5847\/wjem.j.1920-8642.2018.01.003","volume":"9","author":"Y Shen","year":"2018","unstructured":"Shen Y, Tay YC, Teo EWK et al (2018) Association between the elderly frequent attender to the emergency department and 30\u00a0day mortality: a retrospective study over 10 years. World J Emerg Med 9:20\u201325","journal-title":"World J Emerg Med"},{"key":"1738_CR6","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1016\/j.annemergmed.2007.09.011","volume":"51","author":"DC Roberts","year":"2008","unstructured":"Roberts DC, McKay MP, Shaffer A (2008) Increasing rates of emergency department visits for elderly patients in the United States, 1993 to 2003. Ann Emerg Med 51:769\u2013774","journal-title":"Ann Emerg Med"},{"key":"1738_CR7","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.annemergmed.2010.04.015","volume":"56","author":"N Samaras","year":"2010","unstructured":"Samaras N, Chevalley T, Samaras D et al (2010) Older patients in the emergency department: a review. Ann Emerg Med 56:261\u2013269","journal-title":"Ann Emerg Med"},{"key":"1738_CR8","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1067\/mem.2002.121523","volume":"39","author":"F Aminzadeh","year":"2002","unstructured":"Aminzadeh F, Dalziel WB (2002) Older adults in the emergency department: a systematic review of patterns of use, adverse outcomes, and effectiveness of interventions. Ann Emerg Med 39:238\u2013247","journal-title":"Ann Emerg Med"},{"key":"1738_CR9","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1002\/ajh.21298","volume":"84","author":"RS Franco","year":"2009","unstructured":"Franco RS (2009) The measurement and importance of red cell survival. Am J Hematol 84:109\u2013114","journal-title":"Am J Hematol"},{"key":"1738_CR10","doi-asserted-by":"publisher","first-page":"86","DOI":"10.3109\/10408363.2014.992064","volume":"52","author":"GL Salvagno","year":"2015","unstructured":"Salvagno GL, Sanchis-Gomar F, Picanza A et al (2015) Red blood cell distribution width: a simple parameter with multiple clinical applications. Crit Rev Clin Lab Sci 52:86\u2013105","journal-title":"Crit Rev Clin Lab Sci"},{"key":"1738_CR11","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1093\/gerona\/glp163","volume":"65","author":"KV Patel","year":"2010","unstructured":"Patel KV, Semba RD, Ferrucci L et al (2010) Red cell distribution width and mortality in older adults: a meta-analysis. J Gerontol A Biol Sci Med Sci 65:258\u2013265","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"1738_CR12","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1001\/jama.2016.0288","volume":"315","author":"CW Seymour","year":"2016","unstructured":"Seymour CW, Liu VX, Iwashyna TJ et al (2016) Assessment of clinical criteria for sepsis: for the third international consensus definitions for sepsis and septic shock (sepsis-3). JAMA 315:762\u2013774","journal-title":"JAMA"},{"key":"1738_CR13","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1001\/jama.2016.20329","volume":"317","author":"Y Freund","year":"2017","unstructured":"Freund Y, Lemachatti N, Krastinova E et al (2017) Prognostic accuracy of sepsis-3 criteria for in-hospital mortality among patients with suspected infection presenting to the emergency department. JAMA 317:301\u2013308","journal-title":"JAMA"},{"key":"1738_CR14","first-page":"30348","volume":"S0735\u20136757","author":"SMOB Abdullah","year":"2019","unstructured":"Abdullah SMOB, Grand J, Sijapati A et al (2019) qSOFA is a useful prognostic factor for 30\u00a0day mortality in infected patients fulfilling the SIRS criteria for sepsis. Am J Emerg Med pii S0735\u20136757:30348\u201330351","journal-title":"Am J Emerg Med pii"},{"key":"1738_CR15","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/j.annemergmed.2016.10.007","volume":"69","author":"AJ Singer","year":"2017","unstructured":"Singer AJ, Ng J, Thode HC Jr et al (2017) Quick SOFA scores predict mortality in adult emergency department patients with and without suspected infection. Ann Emerg Med 69:475\u2013479","journal-title":"Ann Emerg Med"},{"key":"1738_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.annemergmed.2017.05.022","volume":"71","author":"SY Hwang","year":"2018","unstructured":"Hwang SY, Jo IJ, Lee SU et al (2018) Low accuracy of positive qSOFA criteria for predicting 28\u00a0day mortality in critically IIl septic patients during the early period after emergency department presentation. Ann Emerg Med 71:1-9.e2","journal-title":"Ann Emerg Med"},{"key":"1738_CR17","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1080\/10903127.2016.1274348","volume":"21","author":"M Dorsett","year":"2017","unstructured":"Dorsett M, Kroll M, Smith CS et al (2017) qSOFA Has poor sensitivity for prehospital identification of severe sepsis and septic shock. Prehosp Emerg Care 21:489\u2013497","journal-title":"Prehosp Emerg Care"},{"issue":"12","key":"1738_CR18","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1136\/emermed-2019-208456","volume":"36","author":"SMOB Abdullah","year":"2019","unstructured":"Abdullah SMOB, S\u00f8rensen RH, Dessau RBC et al (2019) Prognostic accuracy of qSOFA in predicting 28\u00a0day mortality among infected patients in an emergency department: a prospective validation study. Emerg Med J 36(12):722\u2013728","journal-title":"Emerg Med J"},{"key":"1738_CR19","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.jns.2008.10.024","volume":"277","author":"C Ani","year":"2009","unstructured":"Ani C, Ovbiagele B (2009) Elevated red blood cell distribution width predicts mortality in persons with known stroke. J Neurol Sci 277:103\u2013108","journal-title":"J Neurol Sci"},{"key":"1738_CR20","doi-asserted-by":"publisher","first-page":"e3692","DOI":"10.1097\/MD.0000000000003692","volume":"95","author":"CK Chen","year":"2016","unstructured":"Chen CK, Lin SC, Wu CC et al (2016) STARD-compliant Article: the utility of red cell distribution width to predict mortality for septic patients visiting the emergency department. Medicine (Baltimore) 95:e3692","journal-title":"Medicine (Baltimore)"},{"key":"1738_CR21","doi-asserted-by":"publisher","first-page":"40","DOI":"10.3109\/07853890.2010.521766","volume":"43","author":"F Wang","year":"2011","unstructured":"Wang F, Pan W, Pan S et al (2011) Red cell distribution width as a novel predictor of mortality in ICU patients. Ann Med 43:40\u201346","journal-title":"Ann Med"},{"key":"1738_CR22","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/j.amjcard.2009.09.027","volume":"105","author":"S Dabbah","year":"2010","unstructured":"Dabbah S, Hammerman H, Markiewicz W et al (2010) Relation between red cell distribution width and clinical outcomes after acute myocardial infarction. Am J Cardiol 105:312\u2013317","journal-title":"Am J Cardiol"},{"key":"1738_CR23","doi-asserted-by":"publisher","first-page":"1923","DOI":"10.1089\/ars.2008.2142","volume":"10","author":"S Ghaffari","year":"2008","unstructured":"Ghaffari S (2008) Oxidative stress in the regulation of normal and neoplastic hematopoiesis. Antioxid Redox Signal 10:1923\u20131940","journal-title":"Antioxid Redox Signal"},{"key":"1738_CR24","doi-asserted-by":"publisher","first-page":"628","DOI":"10.5858\/133.4.628","volume":"133","author":"G Lippi","year":"2009","unstructured":"Lippi G, Targher G, Montagnana M et al (2009) Relation between red blood cell distribution width and inflammatory biomarkers in a large cohort of unselected outpatients. Arch Pathol Lab Med 133:628\u2013632","journal-title":"Arch Pathol Lab Med"},{"key":"1738_CR25","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1016\/j.ahj.2009.07.024","volume":"158","author":"Z F\u00f6rh\u00e9cz","year":"2009","unstructured":"F\u00f6rh\u00e9cz Z, Gombos T, Borgulya G et al (2009) Red cell distribution width in heart failure: prediction of clinical events and relationship with markers of ineffective erythropoiesis, inflammation, renal function, and nutritional state. Am Heart J 158:659\u2013666","journal-title":"Am Heart J"},{"key":"1738_CR26","doi-asserted-by":"publisher","first-page":"15075","DOI":"10.1038\/s41598-019-51439-8","volume":"9","author":"JM Ramos-Rinc\u00f3n","year":"2019","unstructured":"Ramos-Rinc\u00f3n JM, Fern\u00e1ndez-Gil A, Merino E et al (2019) The quick Sepsis-related Organ Failure Assessment (qSOFA) is a good predictor of in-hospital mortality in very elderly patients with bloodstream infections: a retrospective observational study. Sci Rep 9:15075","journal-title":"Sci Rep"},{"key":"1738_CR27","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.cger.2012.09.005","volume":"29","author":"JH Han","year":"2013","unstructured":"Han JH, Wilber ST (2013) Altered mental status in older patients in the emergency department. Clin Geriatr Med 29:101\u2013136","journal-title":"Clin Geriatr Med"},{"key":"1738_CR28","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1016\/j.ajem.2017.10.056","volume":"36","author":"AY Wang","year":"2018","unstructured":"Wang AY, Ma HP, Kao WF et al (2018) Red blood cell distribution width is associated with mortality in elderly patients with sepsis. Am J Emerg Med 36:949\u2013953","journal-title":"Am J Emerg Med"},{"key":"1738_CR29","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1097\/00003246-198510000-00009","volume":"13","author":"WA Knaus","year":"1985","unstructured":"Knaus WA, Draper EA, Wagner DP et al (1985) APACHE II: a severity of disease classification system. Crit Care Med 13:818\u2013829","journal-title":"Crit Care Med"},{"key":"1738_CR30","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1007\/BF01709751","volume":"22","author":"JL Vincent","year":"1996","unstructured":"Vincent JL, Moreno R, Takala J et al (1996) The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction\/failure. On behalf of the working group on sepsis-related problems of the European society of intensive care medicine. Intensive Care Med 22:707\u2013710","journal-title":"Intensive Care Med"}],"container-title":["Aging Clinical and Experimental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40520-020-01738-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40520-020-01738-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40520-020-01738-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,16]],"date-time":"2024-08-16T16:58:17Z","timestamp":1723827497000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40520-020-01738-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,29]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["1738"],"URL":"https:\/\/doi.org\/10.1007\/s40520-020-01738-2","relation":{},"ISSN":["1720-8319"],"issn-type":[{"value":"1720-8319","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,29]]},"assertion":[{"value":"25 March 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 July 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 October 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors do not have any financial or other relationships that might pose any conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"All procedures performed in studies involving patients were in accordance with the ethical standards of the institutions. The protocol was approved by the Institutional Review Board of Seoul St. Mary\u2019s Hospital.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statement of human and animal rights"}},{"value":"Because the clinical measurements were part of routine patient management in the emergency department, informed consent was unnecessary, which was confirmed by the Institutional Review Board.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}