{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T04:04:22Z","timestamp":1788494662381,"version":"build-2803163510"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T00:00:00Z","timestamp":1641859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T00:00:00Z","timestamp":1641859200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Aging Clin Exp Res"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Post-stroke delirium has a negative impact on functional outcome. We explored if there is any association between delirium, subsyndromal delirium and long-term mortality after ischaemic stroke and transient ischaemic attack.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We included 564 patients with ischaemic stroke or transient ischaemic attack. We assessed symptoms of delirium during the first 7\u00a0days after admission. We used Cox proportional hazards models to analyse all-cause mortality during the first 5\u00a0years after stroke.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>We diagnosed delirium in 23.4% and subsyndromal delirium in 10.3% of patients. During the follow-up, 72.7% of patients with delirium, 51.7% of patients with subsyndromal delirium and 22.7% of patients without delirious symptoms died (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Patients with subsyndromal delirium and delirium had higher risk of death in the multivariate analysis (HR 1.72, 95% CI 1.11\u20132.68, <jats:italic>P<\/jats:italic>\u2009=\u20090.016 and HR 3.30, 95% CI 2.29\u20134.76, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001, respectively).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Post-stroke delirium is associated with long-term mortality. Patients with subsyndromal delirium are at the intermediate risk of death.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s40520-021-02071-y","type":"journal-article","created":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T12:03:41Z","timestamp":1641902621000},"page":"1459-1462","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Delirium and subsyndromal delirium are associated with the long-term risk of death after ischaemic stroke"],"prefix":"10.1007","volume":"34","author":[{"given":"Elzbieta","family":"Klimiec-Moskal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Slowik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4086-0729","authenticated-orcid":false,"given":"Tomasz","family":"Dziedzic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,1,11]]},"reference":[{"key":"2071_CR1","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1097\/wnn.0000000000000110","volume":"29","author":"E Klimiec","year":"2016","unstructured":"Klimiec E, Dziedzic T, Kowalska K et al (2016) Knowns and unknowns about delirium in stroke: a review. 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The study protocol was approved by the Bioethics Committee of the Jagiellonian University.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"This article does not contain any studies with animals performed by any of the authors.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and animal rights disclosure"}},{"value":"Written informed consent was obtained from the parents.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}