{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T23:42:18Z","timestamp":1768434138454,"version":"3.49.0"},"reference-count":57,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T00:00:00Z","timestamp":1691366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T00:00:00Z","timestamp":1691366400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100014840","name":"Gemeinsame Bundesausschuss","doi-asserted-by":"publisher","award":["01VSF16017"],"award-info":[{"award-number":["01VSF16017"]}],"id":[{"id":"10.13039\/501100014840","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012940","name":"Universit\u00e4tsklinikum T\u00fcbingen","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012940","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Aging Clin Exp Res"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Nursing home residents (NHR) show high rates of polypharmacy. The HIOPP-3-iTBX study is the first cRCT on medication optimization in nursing homes (NH) in Germany. The intervention did not result in a reduction of PIM and\/or antipsychotics. This analysis looks at structure quality in the HIOPP-3-iTBX study participants.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Aims<\/jats:title>\n                <jats:p>Evaluation of structure quality as part of a cluster-randomized controlled intervention study.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Structure quality in multiprofessional teams from <jats:italic>n<\/jats:italic>\u2009=\u200944 NH (<jats:italic>n<\/jats:italic>\u2009=\u200944 NH directors, <jats:italic>n<\/jats:italic>\u2009=\u200991 family doctors (FD), and <jats:italic>n<\/jats:italic>\u2009=\u200952 pharmacies with <jats:italic>n<\/jats:italic>\u2009=\u200962 pharmacists) was assessed using self-designed questionnaires at baseline. Main aspects of the questionnaires related to the qualification of participants, quality management, the medication process and size of the facilities. All completed questionnaires were included. number of PIM\/antipsychotics was drawn from the baseline medication analysis in 692 NHR. Data were analyzed by descriptive statistics and mixed model logistic regression.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The presence of a nurse with one of the additional qualifications <jats:italic>pain nurse<\/jats:italic> or <jats:italic>Zertifiziertes Curriculum (Zercur) Geriatrie<\/jats:italic> in the participating NH was associated with a lower risk for the prescription of PIM\/antipsychotics. No association between any characteristic in the other participants at baseline was observed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions and discussion<\/jats:title>\n                <jats:p>The results support the known role of nursing qualification in the quality and safety of care. Further studies need to look more closely at how use is made of the additional qualifications within the multiprofessional teams. Perspectively, the results can contribute to the development of quality standards in NH in Germany.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s40520-023-02513-9","type":"journal-article","created":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T18:02:30Z","timestamp":1691431350000},"page":"2227-2235","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The role of qualification and quality management in the prescription of antipsychotics and potentially inappropriate medication (PIM) in nursing home residents in Germany: results of the HIOPP-3-iTBX study"],"prefix":"10.1007","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1127-3090","authenticated-orcid":false,"given":"Regina","family":"Stolz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olaf","family":"Krause","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike","family":"Junius-Walker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petra","family":"Th\u00fcrmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Fuchs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Wilm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anja","family":"Wollny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franziska","family":"Rebentisch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birgitt","family":"Wiese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefanie","family":"Joos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah","family":"Haumann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,8,7]]},"reference":[{"key":"2513_CR1","doi-asserted-by":"publisher","first-page":"204209862093374","DOI":"10.1177\/2042098620933741","volume":"11","author":"M Khezrian","year":"2020","unstructured":"Khezrian M, McNeil CJ, Murray AD et al (2020) An overview of prevalence, determinants and health outcomes of polypharmacy. Ther Adv Drug Saf 11:2042098620933741","journal-title":"Ther Adv Drug Saf"},{"key":"2513_CR2","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1007\/s41999-021-00479-3","volume":"12","author":"F Pazan","year":"2021","unstructured":"Pazan F, Wehling M (2021) Polypharmacy in older adults: a narrative review of definitions, epidemiology and consequences. Eur Geriatr Med 12:443\u2013452","journal-title":"Eur Geriatr Med"},{"key":"2513_CR3","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1016\/j.zefq.2012.10.021","volume":"106","author":"U Jaehde","year":"2012","unstructured":"Jaehde U, Th\u00fcrmann PA (2012) Medication safety in nursing homes. Z Evid Fortbild Qual Gesundhwes 106:712\u2013716","journal-title":"Z Evid Fortbild Qual Gesundhwes"},{"key":"2513_CR4","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1007\/s00103-018-2796-x","volume":"61","author":"U Jaehde","year":"2018","unstructured":"Jaehde U, Th\u00fcrmann P (2018) Arzneimitteltherapiesicherheit bei Heimbewohnern. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 61:1111\u20131118","journal-title":"Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz"},{"key":"2513_CR5","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1093\/gerona\/glr233","volume":"67","author":"G Onder","year":"2012","unstructured":"Onder G, Liperoti R, Fialova D et al (2012) Polypharmacy in nursing home in Europe: results from the SHELTER study. J Gerontol A Biol Sci Med Sci 67:698\u2013704","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"2513_CR6","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.zefq.2016.03.004","volume":"113","author":"F Hoffmann","year":"2016","unstructured":"Hoffmann F, Schmiemann G, D\u00f6rks M (2016) Untersuchungen zu Polypharmazie: Eine Frage der Definition und der verwendeten Daten. Z Evid Fortbild Qual Gesundhwes 113:27\u201335","journal-title":"Z Evid Fortbild Qual Gesundhwes"},{"key":"2513_CR7","first-page":"627","volume":"113","author":"D Mosshammer","year":"2016","unstructured":"Mosshammer D, Haumann H, Morike K et al (2016) Polypharmacy-an upward trend with unpredictable effects. Deutsch Arzteblatt Int 113:627\u2013633","journal-title":"Deutsch Arzteblatt Int"},{"key":"2513_CR8","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1111\/jgs.15767","volume":"67","author":"By the American Geriatrics Society Beers Criteria Update Expert P","year":"2019","unstructured":"By the American Geriatrics Society Beers Criteria Update Expert P (2019) American Geriatrics Society 2019 updated AGS Beers Criteria(R) for potentially inappropriate medication use in older adults. J Am Geriatr Soc 67:674\u2013694","journal-title":"J Am Geriatr Soc"},{"key":"2513_CR9","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1111\/ggi.12890","volume":"16","author":"T Kojima","year":"2016","unstructured":"Kojima T, Mizukami K, Tomita N et al (2016) Screening tool for older persons\u2019 appropriate prescriptions for Japanese: report of the Japan Geriatrics Society Working Group on \u201cGuidelines for medical treatment and its safety in the elderly.\u201d Geriatr Gerontol Int 16:983\u20131001","journal-title":"Geriatr Gerontol Int"},{"key":"2513_CR10","doi-asserted-by":"publisher","first-page":"1713","DOI":"10.1007\/s00228-021-03145-6","volume":"77","author":"B Roux","year":"2021","unstructured":"Roux B, Berthou-Contreras J, Beuscart JB et al (2021) Review of potentially inappropriate medication pr[e]scribing in seniors (remedi[e]s): French implicit and explicit criteria. Eur J Clin Pharmacol 77:1713\u20131724","journal-title":"Eur J Clin Pharmacol"},{"key":"2513_CR11","first-page":"543","volume":"107","author":"S Holt","year":"2010","unstructured":"Holt S, Schmiedl S, Thurmann PA (2010) Potentially inappropriate medications in the elderly: the PRISCUS list. Deutsch Arzteblatt Int 107:543\u2013551","journal-title":"Deutsch Arzteblatt Int"},{"key":"2513_CR12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0146811","volume":"11","author":"HG Endres","year":"2016","unstructured":"Endres HG, Kaufmann-Kolle P, Steeb V et al (2016) Association between potentially inappropriate medication (PIM) use and risk of hospitalization in older adults: an observational study based on routine data comparing PIM use with use of PIM alternatives. PLoS ONE 11:e0146811","journal-title":"PLoS ONE"},{"key":"2513_CR13","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1177\/1060028019853069","volume":"53","author":"XX Xing","year":"2019","unstructured":"Xing XX, Zhu C, Liang HY et al (2019) Associations between potentially inappropriate medications and adverse health outcomes in the elderly: a systematic review and meta-analysis. Ann Pharmacother 53:1005\u20131019","journal-title":"Ann Pharmacother"},{"key":"2513_CR14","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1007\/s40266-017-0441-2","volume":"34","author":"D Heider","year":"2017","unstructured":"Heider D, Matschinger H, Meid AD et al (2017) Health service use, costs, and adverse events associated with potentially inappropriate medication in old age in Germany: retrospective matched cohort study. Drugs Aging 34:289\u2013301","journal-title":"Drugs Aging"},{"key":"2513_CR15","doi-asserted-by":"publisher","first-page":"1525","DOI":"10.1007\/s00228-015-1950-8","volume":"71","author":"K Hedna","year":"2015","unstructured":"Hedna K, Hakkarainen KM, Gyllensten H et al (2015) Potentially inappropriate prescribing and adverse drug reactions in the elderly: a population-based study. Eur J Clin Pharmacol 71:1525\u20131533","journal-title":"Eur J Clin Pharmacol"},{"key":"2513_CR16","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1093\/ageing\/afv166","volume":"45","author":"S Cullinan","year":"2016","unstructured":"Cullinan S, O\u2019Mahony D, O\u2019Sullivan D et al (2016) Use of a frailty index to identify potentially inappropriate prescribing and adverse drug reaction risks in older patients. Age Ageing 45:115\u2013120","journal-title":"Age Ageing"},{"key":"2513_CR17","doi-asserted-by":"publisher","first-page":"187e7","DOI":"10.1016\/j.jamda.2011.03.007","volume":"13","author":"T Richter","year":"2012","unstructured":"Richter T, Mann E, Meyer G et al (2012) Prevalence of psychotropic medication use among German and Austrian nursing home residents: a comparison of 3 cohorts. J Am Med Dir Assoc 13:187e7-187e13","journal-title":"J Am Med Dir Assoc"},{"key":"2513_CR18","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1111\/jgs.14162","volume":"64","author":"MS Bakken","year":"2016","unstructured":"Bakken MS, Schj\u00f8tt J, Engeland A et al (2016) Antipsychotic drugs and risk of hip fracture in people aged 60 and older in Norway. J Am Geriatr Soc 64:1203\u20131209","journal-title":"J Am Geriatr Soc"},{"key":"2513_CR19","doi-asserted-by":"publisher","first-page":"e76","DOI":"10.4088\/JCP.15m10303","volume":"78","author":"R Liperoti","year":"2017","unstructured":"Liperoti R, Sganga F, Landi F et al (2017) Antipsychotic drug interactions and mortality among nursing home residents with cognitive impairment. J Clin Psychiatry 78:e76\u2013e82","journal-title":"J Clin Psychiatry"},{"key":"2513_CR20","unstructured":"Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) e. V. (2021) Haus\u00e4rztliche Leitlinie: Multimedikation. https:\/\/www.awmf.org\/leitlinien\/detail\/ll\/053-043.html. Accessed 20 Dec 2022"},{"key":"2513_CR21","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.apnr.2017.02.021","volume":"35","author":"N Fleischmann","year":"2017","unstructured":"Fleischmann N, Geister C, Hoell A et al (2017) Interprofessional collaboration in nursing homes (interprof): a grounded theory study of nurse experiences of general practitioner visits. Appl Nurs Res 35:118\u2013125","journal-title":"Appl Nurs Res"},{"key":"2513_CR22","unstructured":"Deutsches Netzwerk f\u00fcr Qualit\u00e4tsentwicklung in der Pflege (2020) Expertenstandard Schmerzmanagement in der Pflege. Aktualisierte Version. https:\/\/www.dnqp.de\/fileadmin\/HSOS\/Homepages\/DNQP\/Dateien\/Expertenstandards\/Schmerzmanagement_2020\/Schmerz-Akt2020_Auszug.pdf. Accessed 28 Nov 2022"},{"key":"2513_CR23","unstructured":"Deutsche Gesellschaft f\u00fcr Psychiatrie und Psychotherapie, Psychosomatik und Nervenheilkunde (DGPPN), Deutsche Gesellschaft f\u00fcr Neurologie (DGN) (2016) S3-Leitlinie \u201eDemenz\u201c. https:\/\/www.awmf.org\/uploads\/tx_szleitlinien\/038-013l_S3-Demenzen-2016-07.pdf. Accessed 28 Nov 2022"},{"key":"2513_CR24","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1016\/j.zefq.2013.07.011","volume":"108","author":"C Mahler","year":"2014","unstructured":"Mahler C, Freund T, Baldauf A et al (2014) Structured medication management in primary care - a tool to promote medication safety. Z Evid Fortbild Qual Gesundhwes 108:258\u2013269","journal-title":"Z Evid Fortbild Qual Gesundhwes"},{"key":"2513_CR25","unstructured":"Medizinischer Dienst Bund (2022) Qualit\u00e4tspr\u00fcfungen von Pflegeeinrichtungen. https:\/\/md-bund.de\/themen\/pflegequalitaet\/qualitaetspruefungen.html. Accessed 8 July 2022"},{"key":"2513_CR26","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1002\/nop2.654","volume":"8","author":"B Oner","year":"2021","unstructured":"Oner B, Zengul FD, Oner N et al (2021) Nursing-sensitive indicators for nursing care: a systematic review (1997\u20132017). Nurs Open 8:1005\u20131022","journal-title":"Nurs Open"},{"key":"2513_CR27","unstructured":"Centers for Medicare & Medicaid Services (CMS) (2022) Quality measures. https:\/\/www.cms.gov\/Medicare\/Quality-Initiatives-Patient-Assessment-Instruments\/NursingHomeQualityInits\/NHQIQualityMeasures. Accessed 30 July 2022"},{"key":"2513_CR28","first-page":"2003","volume-title":"An introduction to quality assurance in health care","author":"A Donabedian","year":"2003","unstructured":"Donabedian A, Bashur R (2003) An introduction to quality assurance in health care. Oxford University Press, New York, p 2003"},{"key":"2513_CR29","first-page":"705","volume":"118","author":"U Junius-Walker","year":"2021","unstructured":"Junius-Walker U, Krause O, Th\u00fcrmann P et al (2021) Drug safety for nursing-home residents-findings of a pragmatic, cluster-randomized, controlled intervention Trialin 44 nursing homes. Deutsch Arzteblatt Int 118:705\u2013712","journal-title":"Deutsch Arzteblatt Int"},{"key":"2513_CR30","unstructured":"Bund MDdS, (MDS) dKeV (2019) Richtlinien des GKV-Spitzenverbandes f\u00fcr die Qualit\u00e4tspr\u00fcfung in Pflegeeinrichtungen nach \u00a7 114 SGB XI. Vollstation\u00e4re Pflege 2019. Available from https:\/\/md-bund.de\/suchergebnis.html?tx_solr%5Bq%5D=Pr%C3%BCfbogen"},{"key":"2513_CR31","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.zefq.2020.07.002","volume":"156","author":"C Kirsch","year":"2020","unstructured":"Kirsch C, Doyle I-M, Krause O et al (2020) Lessons learned: challenges faced in the recruitment process for the cluster-randomized nursing home study HIOPP-3 iTBX. Z Evid Fortbild Qual Gesundhwes 156:24\u201332","journal-title":"Z Evid Fortbild Qual Gesundhwes"},{"key":"2513_CR32","first-page":"14","volume":"12","author":"P L\u00fcttinger","year":"1988","unstructured":"L\u00fcttinger P, K\u00f6nig W (1988) Die Entwicklung einer international vergleichbaren Klassifikation f\u00fcr Bildungssysteme. ZUMA Nachrichten 12:14","journal-title":"ZUMA Nachrichten"},{"key":"2513_CR33","unstructured":"Bundesministerium f\u00fcr Gesundheit (2006) Rahmenempfehlungen zum Umgang mit herausforderndem Verhalten bei Menschen mit Demenz in der station\u00e4ren Altenhilfe. https:\/\/www.bundesgesundheitsministerium.de\/fileadmin\/Dateien\/Publikationen\/Pflege\/Berichte\/Bericht_Rahmenempfehlungen_zum_Umgang_mit_herausforderndem_Verhalten_bei_Menschen_mit_Demenz_in_der_stationaeren_Altenhilfe.pdf. Accessed 15 Nov 2022"},{"key":"2513_CR34","first-page":"84","volume":"60","author":"S Branitzki","year":"2007","unstructured":"Branitzki S (2007) Redu-Fix\u2014a model for reducing physical restraint: protecting nursing home residence from mobility limitations. Pflege Z 60:84\u201387","journal-title":"Pflege Z"},{"key":"2513_CR35","doi-asserted-by":"crossref","unstructured":"Wassermann J, Kirsch S (2022) Werdenfelser Weg [19.09.2022]. https:\/\/www.werdenfelser-weg-original.de","DOI":"10.5771\/9783748911784-987-2"},{"key":"2513_CR36","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1111\/jgs.15195","volume":"66","author":"SL Gray","year":"2018","unstructured":"Gray SL, Hart LA, Perera S et al (2018) Meta-analysis of interventions to reduce adverse drug reactions in older adults. J Am Geriatr Soc 66:282\u2013288","journal-title":"J Am Geriatr Soc"},{"key":"2513_CR37","doi-asserted-by":"publisher","first-page":"6724","DOI":"10.3390\/ijerph19116724","volume":"19","author":"S Mucherino","year":"2022","unstructured":"Mucherino S, Casula M, Galimberti F et al (2022) (2022) The effectiveness of interventions to evaluate and reduce healthcare costs of potentially inappropriate prescriptions among the older adults: a systematic review. Int J Environ Res Public Health 19:6724","journal-title":"Int J Environ Res Public Health"},{"key":"2513_CR38","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1007\/978-3-662-58935-9_13","volume-title":"Pflege-Report 2019: Mehr Personal in der Langzeitpflege - aber woher?","author":"M Ewers","year":"2020","unstructured":"Ewers M, Lehmann Y (2020) Hochschulisch qualifizierte Pflegende in der Langzeitversorgung?! In: Jacobs K, Kuhlmey A, Gre\u00df S et al (eds) Pflege-Report 2019: Mehr Personal in der Langzeitpflege - aber woher? Springer, Berlin Heidelberg, pp 167\u2013177"},{"key":"2513_CR39","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1111\/jan.14644","volume":"77","author":"K Basinska","year":"2021","unstructured":"Basinska K, Wellens NIH, Simon M et al (2021) Registered nurses in expanded roles improve care in nursing homes: Swiss perspective based on the modified Delphi method. J Adv Nurs 77:742\u2013754","journal-title":"J Adv Nurs"},{"key":"2513_CR40","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1186\/s12913-021-06803-8","volume":"21","author":"M Toles","year":"2021","unstructured":"Toles M, Col\u00f3n-Emeric C, Moreton E et al (2021) Quality improvement studies in nursing homes: a scoping review. BMC Health Serv Res 21:803","journal-title":"BMC Health Serv Res"},{"key":"2513_CR41","first-page":"97","volume-title":"Qualit\u00e4tsmessungmit Routinedaten in deutschen Pflegeheimen: Eine erste Standortbestimmung. Pflege-Report 2018","author":"A Schwinger","year":"2018","unstructured":"Schwinger A, Behrendt S, Tsiasioti C et al (2018) Qualit\u00e4tsmessungmit Routinedaten in deutschen Pflegeheimen: Eine erste Standortbestimmung. Pflege-Report 2018. Springer, Berlin, pp 97\u2013122"},{"key":"2513_CR42","doi-asserted-by":"publisher","first-page":"569","DOI":"10.2217\/pmt-2019-0024","volume":"9","author":"JV Pergolizzi","year":"2019","unstructured":"Pergolizzi JV, Raffa RB, Paladini A et al (2019) Treating pain in patients with dementia and the possible concomitant relief of symptoms of agitation. Pain Manage 9:569\u2013582","journal-title":"Pain Manage"},{"key":"2513_CR43","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1007\/s40122-019-0111-7","volume":"8","author":"L Cravello","year":"2019","unstructured":"Cravello L, Di Santo S, Varrassi G et al (2019) Chronic pain in the elderly with cognitive decline: a narrative review. Pain Ther 8:53\u201365","journal-title":"Pain Ther"},{"key":"2513_CR44","first-page":"1","volume":"11","author":"SA Moreira","year":"2019","unstructured":"Moreira SA, Novak P (2019) Effects of pain on cognitive function and mobility. J Clin Trials 11:1\u201310","journal-title":"J Clin Trials"},{"key":"2513_CR45","doi-asserted-by":"publisher","first-page":"1181","DOI":"10.1016\/j.pain.2013.03.002","volume":"154","author":"C Berryman","year":"2013","unstructured":"Berryman C, Stanton TR, Jane Bowering K et al (2013) Evidence for working memory deficits in chronic pain: a systematic review and meta-analysis. Pain 154:1181\u20131196","journal-title":"Pain"},{"key":"2513_CR46","doi-asserted-by":"publisher","first-page":"972","DOI":"10.1016\/j.pain.2013.01.013","volume":"154","author":"NI Landr\u00f8","year":"2013","unstructured":"Landr\u00f8 NI, Fors EA, V\u00e5penstad LL et al (2013) The extent of neurocognitive dysfunction in a multidisciplinary pain centre population. Is there a relation between reported and tested neuropsychological functioning? Pain 154:972\u2013977","journal-title":"Pain"},{"key":"2513_CR47","doi-asserted-by":"publisher","first-page":"1435","DOI":"10.1016\/j.jpain.2018.06.009","volume":"19","author":"G van der Leeuw","year":"2018","unstructured":"van der Leeuw G, Ayers E, Leveille SG et al (2018) The effect of pain on major cognitive impairment in older adults. J Pain 19:1435\u20131444","journal-title":"J Pain"},{"key":"2513_CR48","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1007\/s40122-022-00376-y","volume":"11","author":"M Rekatsina","year":"2022","unstructured":"Rekatsina M, Paladini A, Viswanath O et al (2022) Opioids in the elderly patients with cognitive impairment: a narrative review. Pain Ther 11:381\u2013394","journal-title":"Pain Ther"},{"key":"2513_CR49","first-page":"1649","volume":"18","author":"JYW Liu","year":"2016","unstructured":"Liu JYW, Leung DYP (2016) Pain treatments for nursing home residents with advanced dementia and substantial impaired communication: a cross-sectional analysis at baseline of a cluster randomized controlled trial. Pain Med 18:1649\u20131657","journal-title":"Pain Med"},{"key":"2513_CR50","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD013339.pub2","author":"C Manietta","year":"2022","unstructured":"Manietta C, Labont\u00e9 V, Thiesemann R et al (2022) Algorithm-based pain management for people with dementia in nursing homes. Cochrane Database System Rev. https:\/\/doi.org\/10.1002\/14651858.CD013339.pub2","journal-title":"Cochrane Database System Rev"},{"key":"2513_CR51","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1186\/s12904-020-00683-1","volume":"19","author":"P Wegier","year":"2020","unstructured":"Wegier P, Varenbut J, Bernstein M et al (2020) \u201cNo thanks, I don\u2019t want to see snakes again\u201d: a qualitative study of pain management versus preservation of cognition in palliative care patients. BMC Palliat Care 19:182","journal-title":"BMC Palliat Care"},{"key":"2513_CR52","doi-asserted-by":"publisher","first-page":"2","DOI":"10.18773\/austprescr.2022.002","volume":"45","author":"G Wong","year":"2022","unstructured":"Wong G (2022) Pharmacological management of chronic non-cancer pain in frail older people. Aust Prescr 45:2\u20137","journal-title":"Aust Prescr"},{"key":"2513_CR53","first-page":"24","volume":"17","author":"K Hager","year":"2017","unstructured":"Hager K, Krause O (2017) Neuroleptika bei Demenzpatienten? Absetzversuch lohnt sich! Der Allgemeinarzt 17:24\u201328","journal-title":"Der Allgemeinarzt"},{"key":"2513_CR54","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1017\/S146342361700024X","volume":"18","author":"G Tsakitzidis","year":"2017","unstructured":"Tsakitzidis G, Anthierens S, Timmermans O et al (2017) Do not confuse multidisciplinary task management in nursing homes with interprofessional care! Prim Health Care Res Dev 18:591\u2013602","journal-title":"Prim Health Care Res Dev"},{"key":"2513_CR55","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1016\/j.jamda.2014.06.012","volume":"15","author":"J Thompson Coon","year":"2014","unstructured":"Thompson Coon J, Abbott R, Rogers M et al (2014) Interventions to reduce inappropriate prescribing of antipsychotic medications in people with dementia resident in care homes: a systematic review. J Am Med Dir Assoc 15:706\u2013718","journal-title":"J Am Med Dir Assoc"},{"key":"2513_CR56","doi-asserted-by":"publisher","DOI":"10.1016\/j.nedt.2021.104926","volume":"104","author":"NE Dijkstra","year":"2021","unstructured":"Dijkstra NE, De Baetselier E, Dilles T et al (2021) Developing a competence framework for nurses in pharmaceutical care: a Delphi study. Nurse Educ Today 104:104926","journal-title":"Nurse Educ Today"},{"key":"2513_CR57","unstructured":"Jaehde U (2020) Strukturiertes interprofessionelles Studienangebot zur Arzneimitteltherapiesicherheit: Bedarfsanalyse und Konzeption eines Mustercurriculums (SINA): Abschlussbericht zum BMG-gef\u00f6rderten Forschungsvorhaben: Pharmazeutisches Insitut, Rheinische Friedrich-Wilhelms-Universit\u00e4t Bonn [20.12.2022]. https:\/\/www.zem.uni-bonn.de\/news\/abschlussbericht-201estrukturiertes-interprofessionelles-studienangebot-zur-arzneimitteltherapiesicherheit-sina-201c"}],"container-title":["Aging Clinical and Experimental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40520-023-02513-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40520-023-02513-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40520-023-02513-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T18:15:46Z","timestamp":1695665746000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40520-023-02513-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,7]]},"references-count":57,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2023,10]]}},"alternative-id":["2513"],"URL":"https:\/\/doi.org\/10.1007\/s40520-023-02513-9","relation":{},"ISSN":["1720-8319"],"issn-type":[{"value":"1720-8319","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,7]]},"assertion":[{"value":"28 February 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 July 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 August 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"On behalf of all authors, the corresponding author states that there is no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The Ethics Committee of the Hannover Medical University approved the Masters Ethics Application (No. 7655).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"This study was performed in line with the principles of the Declaration of Helsinki and results are reported in regard of the CONSORT Statement. The Medical Research Council (MRC) Guideline \u201cDeveloping and evaluating complex interventions\u2014new guidance\u201d was applied in the intervention development.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statement of human and animal rights"}},{"value":"Informed consent was obtained from all individual participants included in the study or their legal guardians.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}