{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T07:15:40Z","timestamp":1785395740899,"version":"3.55.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T00:00:00Z","timestamp":1710288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T00:00:00Z","timestamp":1710288000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Aging Clin Exp Res"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>This study aims to compare frequency and coexistence of geriatric syndromes in older patients with dementia to those without dementia.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>1392 patients admitted to geriatric outpatient clinics were evaluated. Evaluations for eleven geriatric syndromes including polypharmacy, malnutrition, fraility, sarcopenia, dysphagia, urinary incontinence, fear of falling, falls, insomnia, excessive daytime sleepiness, and orthostatic hypotension (OH) were carried out in consultation with the patient and the caregiver. Two groups with and without dementia were matched according to age and gender using the propensity score matching method.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 738 patients, 369 with dementia and 369 without dementia were included, of whom 70.1% were female and the mean age was 80.5\u2009\u00b1\u20096.8. Polypharmacy, malnutrition, frailty, sarcopenia, dysphagia, fear of falling, and excessive daytime sleepiness were significantly higher in patients with dementia (p\u2009&lt;\u20090.05). There was no difference between OH, urinary incontinence and insomnia between groups (p\u2009&gt;\u20090.05). The co-existence of 0, 1, 2, 3, 4 and\u2009\u2265\u20095 geriatric syndromes in the same patient was 4.3%, 10.2%, 11.8%, 16.8%, 13.4% and 43.7% in non-dementia patients, respectively; 2.4%, 7.2%, 9.6%, 8.3%, 10.4% and 62.1% in those with dementia, respectively (p\u2009&lt;\u20090.05).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The presence and co-existence of geriatric syndromes is common in patients with dementia. These geriatric syndromes should be examined by clinicians and healthcare professionals who work with the demented population, so that more successful management of dementia patients may be achieved.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s40520-024-02724-8","type":"journal-article","created":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T07:24:32Z","timestamp":1710314672000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["The prevalence\u00a0and co-existence of geriatric syndromes in older patients with dementia compared to those without dementia"],"prefix":"10.1007","volume":"36","author":[{"given":"Pinar","family":"Soysal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,13]]},"reference":[{"key":"2724_CR1","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1111\/J.1532-5415.2007.01156.X","volume":"55","author":"SK Inouye","year":"2007","unstructured":"Inouye SK, Studenski S, Tinetti ME et al (2007) Geriatric syndromes: clinical, research, and policy implications of a core geriatric concept. J Am Geriatr Soc 55:780\u2013791. https:\/\/doi.org\/10.1111\/J.1532-5415.2007.01156.X","journal-title":"J Am Geriatr Soc"},{"key":"2724_CR2","doi-asserted-by":"publisher","first-page":"1899","DOI":"10.2147\/CIA.S180281","volume":"13","author":"E Ates Bulut","year":"2018","unstructured":"Ates Bulut E, Soysal P, Isik AT (2018) Frequency and coincidence of geriatric syndromes according to age groups: single-center experience in Turkey between 2013 and 2017. Clin Interv Aging 13:1899. https:\/\/doi.org\/10.2147\/CIA.S180281","journal-title":"Clin Interv Aging"},{"key":"2724_CR3","unstructured":"Marie Curie Cancer Care (2021). Facts and figures. [cited 15 January 2022]. https:\/\/www.mariecurie.org.uk\/globalassets\/media\/documents\/media-centre\/documents-media-resources\/facts-and-figures.pdf."},{"key":"2724_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/J.ARCHGER.2019.103997","volume":"87","author":"L Zheng","year":"2020","unstructured":"Zheng L, Li G, Gao D et al (2020) Cognitive frailty as a predictor of dementia among older adults: a systematic review and meta-analysis. Arch Gerontol Geriatr 87:103997. https:\/\/doi.org\/10.1016\/J.ARCHGER.2019.103997","journal-title":"Arch Gerontol Geriatr"},{"key":"2724_CR5","doi-asserted-by":"publisher","first-page":"2599","DOI":"10.1007\/S40520-020-01774-Y","volume":"33","author":"P Soysal","year":"2021","unstructured":"Soysal P, Tan SG (2021) The prevalence and co-incidence of geriatric syndromes in older patients with early-stage Alzheimer\u2019s disease and dementia with lewy bodies. Ag Clin Exp Res 33:2599\u20132603. https:\/\/doi.org\/10.1007\/S40520-020-01774-Y","journal-title":"Ag Clin Exp Res"},{"key":"2724_CR6","doi-asserted-by":"publisher","first-page":"123","DOI":"10.4235\/agmr.2017.21.3.123","volume":"21","author":"S Kim","year":"2017","unstructured":"Kim S, Ahn H, Lee S et al (2017) Risk factors of geriatric syndromes in Korean population. Ann Geriatr Med Res 21:123\u2013130. https:\/\/doi.org\/10.4235\/agmr.2017.21.3.123","journal-title":"Ann Geriatr Med Res"},{"key":"2724_CR7","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1007\/s40520-021-01966-0","volume":"34","author":"C Heybeli","year":"2022","unstructured":"Heybeli C, Soysal P, Oktan MA et al (2022) Associations between nutritional factors and excessive daytime sleepiness in older patients with chronic kidney disease. Aging Clin Exp Res 34:573\u2013581. https:\/\/doi.org\/10.1007\/s40520-021-01966-0","journal-title":"Aging Clin Exp Res"},{"key":"2724_CR8","doi-asserted-by":"publisher","first-page":"2134","DOI":"10.1016\/J.JAMDA.2021.05.035","volume":"22","author":"S Koc Okudur","year":"2021","unstructured":"Koc Okudur S, Soysal P (2021) Excessive daytime sleepiness is associated with malnutrition, dysphagia, and vitamin D deficiency in older adults. J Am Med Dir Assoc 22:2134\u20132139. https:\/\/doi.org\/10.1016\/J.JAMDA.2021.05.035","journal-title":"J Am Med Dir Assoc"},{"key":"2724_CR9","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/J.EXGER.2019.02.019","volume":"120","author":"P Soysal","year":"2019","unstructured":"Soysal P, Perera G, Isik AT et al (2019) The relationship between polypharmacy and trajectories of cognitive decline in people with dementia: a large representative cohort study. Exp Gerontol 120:62\u201367. https:\/\/doi.org\/10.1016\/J.EXGER.2019.02.019","journal-title":"Exp Gerontol"},{"key":"2724_CR10","doi-asserted-by":"publisher","first-page":"2675","DOI":"10.1007\/s40520-023-02538-0","volume":"35","author":"Z Sucuoglu Isleyen","year":"2023","unstructured":"Sucuoglu Isleyen Z, Besiroglu M, Yasin AI et al (2023) The risk of malnutrition and its clinical implications in older patients with cancer. Aging Clin Exp Res 35:2675\u20132683. https:\/\/doi.org\/10.1007\/s40520-023-02538-0","journal-title":"Aging Clin Exp Res"},{"key":"2724_CR11","doi-asserted-by":"publisher","DOI":"10.1016\/J.ARCHGER.2021","volume":"96","author":"MG Borda","year":"2021","unstructured":"Borda MG, Castellanos-Perilla N, Tovar-Rios DA et al (2021) Polypharmacy is associated with functional decline in alzheimer\u2019s disease and lewy body dementia. Arch Gerontol Geriatr 96:104459. https:\/\/doi.org\/10.1016\/J.ARCHGER.2021","journal-title":"Arch Gerontol Geriatr"},{"key":"2724_CR12","doi-asserted-by":"publisher","first-page":"1430","DOI":"10.1016\/J.JAMDA.2020.06.051","volume":"21","author":"P Soysal","year":"2020","unstructured":"Soysal P, Dokuzlar O, Erken N et al (2020) The relationship between dementia subtypes and nutritional parameters in older adults. J Am Med Dir Assoc 21:1430\u20131435. https:\/\/doi.org\/10.1016\/J.JAMDA.2020.06.051","journal-title":"J Am Med Dir Assoc"},{"key":"2724_CR13","doi-asserted-by":"publisher","first-page":"5659","DOI":"10.1002\/GPS","volume":"37","author":"P Soysal","year":"2021","unstructured":"Soysal P, Tan SG, Rogowska M et al (2021) Weight loss in Alzheimer\u2019s disease, vascular dementia and dementia with lewy bodies: impact on mortality and hospitalization by dementia subtype. Int J Geriatr Psychiatry 37:5659. https:\/\/doi.org\/10.1002\/GPS","journal-title":"Int J Geriatr Psychiatry"},{"key":"2724_CR14","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1017\/S0029665112002753","volume":"72","author":"G Sergi","year":"2013","unstructured":"Sergi G, de Rui M, Coin A et al (2013) Weight loss and Alzheimer\u2019s disease: temporal and aetiologic connections. Proc Nutr Soc 72:160\u2013165. https:\/\/doi.org\/10.1017\/S0029665112002753","journal-title":"Proc Nutr Soc"},{"key":"2724_CR15","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1017\/S1041610213000446","volume":"25","author":"L Velayudhan","year":"2013","unstructured":"Velayudhan L, Pritchard M, Powell JF et al (2013) Smell identification function as a severity and progression marker in Alzheimer\u2019s disease. Int Psychogeriatr 25:1157\u20131166. https:\/\/doi.org\/10.1017\/S1041610213000446","journal-title":"Int Psychogeriatr"},{"key":"2724_CR16","doi-asserted-by":"publisher","first-page":"1368","DOI":"10.1136\/JNNP-2016-313660","volume":"87","author":"P Soysal","year":"2016","unstructured":"Soysal P, Isik AT, Stubbs B et al (2016) Acetylcholinesterase inhibitors are associated with weight loss in older people with dementia: a systematic review and meta-analysis. J Neurol Neurosurg Psychiatry 87:1368\u20131374. https:\/\/doi.org\/10.1136\/JNNP-2016-313660","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2724_CR17","doi-asserted-by":"publisher","DOI":"10.1159\/000520326","author":"KJ Banda","year":"2021","unstructured":"Banda KJ, Chu H, Chen R et al (2021) Prevalence of oropharyngeal dysphagia and risk of pneumonia, malnutrition, and mortality in adults aged 60 years and older: a meta-analysis. Gerontology. https:\/\/doi.org\/10.1159\/000520326","journal-title":"Gerontology"},{"key":"2724_CR18","doi-asserted-by":"publisher","first-page":"1540","DOI":"10.1016\/J.JAMDA.2019.06.008","volume":"20","author":"HM Noh","year":"2019","unstructured":"Noh HM, Roh YK, Song HJ et al (2019) Severe fear of falling is associated with cognitive decline in older adults: a 3\u00a0year prospective study. J Am Med Dir Assoc 20:1540\u20131547. https:\/\/doi.org\/10.1016\/J.JAMDA.2019.06.008","journal-title":"J Am Med Dir Assoc"},{"key":"2724_CR19","doi-asserted-by":"publisher","first-page":"2709","DOI":"10.1007\/S40520-019-01338-9","volume":"33","author":"A Langeard","year":"2021","unstructured":"Langeard A, Desjardins-Cr\u00e9peau L, Lemay M et al (2021) Cognitive performances better identify fallers than mobility assessment among older adults with fear of falling. Aging Clin Exp Res 33:2709\u20132714. https:\/\/doi.org\/10.1007\/S40520-019-01338-9","journal-title":"Aging Clin Exp Res"},{"key":"2724_CR20","doi-asserted-by":"publisher","DOI":"10.1016\/J.EXGER.2020","volume":"146","author":"AM Al-Harrasi","year":"2021","unstructured":"Al-Harrasi AM, Iqbal E, Tsamakis K et al (2021) Motor signs in alzheimer\u2019s disease and vascular dementia: detection through natural language processing, co-morbid features and relationship to adverse outcomes. Exp Gerontol 146:111223. https:\/\/doi.org\/10.1016\/J.EXGER.2020","journal-title":"Exp Gerontol"},{"key":"2724_CR21","doi-asserted-by":"publisher","DOI":"10.1016\/J.EXGER.2021","author":"P Soysal","year":"2021","unstructured":"Soysal P, Tan SG, Smith L (2021) A comparison of the prevalence of fear of falling between older patients with lewy body dementia, Alzheimer\u2019s disease, and without dementia. Exp Gerontol. https:\/\/doi.org\/10.1016\/J.EXGER.2021","journal-title":"Exp Gerontol"},{"key":"2724_CR22","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1002\/GPS.5133","volume":"34","author":"G Peeters","year":"2019","unstructured":"Peeters G, Feeney J, Carey D et al (2019) Fear of falling: a manifestation of executive dysfunction? Int J Geriatr Psychiatry 34:1275\u20131282. https:\/\/doi.org\/10.1002\/GPS.5133","journal-title":"Int J Geriatr Psychiatry"},{"key":"2724_CR23","doi-asserted-by":"publisher","first-page":"18168299","DOI":"10.3390\/IJERPH","volume":"18","author":"CF Chang","year":"2021","unstructured":"Chang CF, Yeh YL, Chang HY et al (2021) Prevalence and risk factors of sarcopenia among older adults aged \u226565 years admitted to daycare centers of taiwan: using awgs 2019 guidelines. Int J Environ Res Public Health 18:18168299. https:\/\/doi.org\/10.3390\/IJERPH","journal-title":"Int J Environ Res Public Health"},{"key":"2724_CR24","doi-asserted-by":"publisher","DOI":"10.1007\/S10072-021-05728-8","author":"J Cho","year":"2021","unstructured":"Cho J, Park M, Moon WJ et al (2021) Sarcopenia in patients with dementia: correlation of temporalis muscle thickness with appendicular muscle mass. Neurol Sci. https:\/\/doi.org\/10.1007\/S10072-021-05728-8","journal-title":"Neurol Sci"},{"key":"2724_CR25","doi-asserted-by":"publisher","DOI":"10.1016\/J.ARCHGER.2020","volume":"92","author":"SJ Waite","year":"2021","unstructured":"Waite SJ, Maitland S, Thomas A et al (2021) Sarcopenia and frailty in individuals with dementia: a systematic review. Arch Gerontol Geriatr 92:104268. https:\/\/doi.org\/10.1016\/J.ARCHGER.2020","journal-title":"Arch Gerontol Geriatr"},{"key":"2724_CR26","doi-asserted-by":"publisher","DOI":"10.1002\/ALZ.049718","author":"IC M\u00e1rquez","year":"2021","unstructured":"M\u00e1rquez IC, Garcia-Cifuentes E, Velandia FR et al (2021) Motoric cognitive risk syndrome: prevalence and cognitive performance. Alzheimer\u2019s Dementia. https:\/\/doi.org\/10.1002\/ALZ.049718","journal-title":"Alzheimer\u2019s Dementia"},{"key":"2724_CR27","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.5665\/SLEEP.2070","volume":"35","author":"I Jaussent","year":"2012","unstructured":"Jaussent I, Bouyer J, Ancelin ML et al (2012) Excessive sleepiness is predictive of cognitive decline in the elderly. Sleep 35:1201\u20131207. https:\/\/doi.org\/10.5665\/SLEEP.2070","journal-title":"Sleep"},{"key":"2724_CR28","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/J.PARKRELDIS.2021.02.016","volume":"85","author":"F Feng","year":"2021","unstructured":"Feng F, Cai YY, Hou YB et al (2021) Excessive daytime sleepiness in Parkinson\u2019s disease: a systematic review and meta-analysis. Parkinsonism Relat Disord 85:133\u2013140. https:\/\/doi.org\/10.1016\/J.PARKRELDIS.2021.02.016","journal-title":"Parkinsonism Relat Disord"}],"container-title":["Aging Clinical and Experimental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40520-024-02724-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40520-024-02724-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40520-024-02724-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T07:44:31Z","timestamp":1710315871000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40520-024-02724-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,13]]},"references-count":28,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["2724"],"URL":"https:\/\/doi.org\/10.1007\/s40520-024-02724-8","relation":{},"ISSN":["1720-8319"],"issn-type":[{"value":"1720-8319","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,13]]},"assertion":[{"value":"19 January 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 February 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 March 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The researchers claim no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All the procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Declaration of Helsinki and its later amendments.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statement of human participants and\/or animals"}},{"value":"Informed consent was provided by each participant or a legal guardian before participating in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}],"article-number":"66"}}