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Dual-task (DT) walking performance is a reliable indicator of iNPH but less is known about the role of cognitive reserve (CR) in predicting DT walking performance.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Aims<\/jats:title>\n                <jats:p>The objective of this study was to evaluate the contribution of CR on DT walking in healthy controls (HC) and in iNPH patients (iNPH-P).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>68 iNPH-P (77.2 +\/- 6.7 years old) and 28 HC (74.5 +\/- 5.7 years old) were evaluated on their single-task walking (<jats:italic>Vsimple<\/jats:italic>) and on 4 DT walking (walking and counting or counting backwards, naming animals, naming words beginning with the letter P) (<jats:italic>Vcount<\/jats:italic>,<jats:italic> VcountB<\/jats:italic>,<jats:italic> Vanimals and Vletter<\/jats:italic> respectively). The contribution of CR on the different DT walking speeds was compared between HC and iNPH-P. In iNPH-P, the contribution of CR on the walking speeds was compared with regard to other cognitive, functional, and socio-demographic variables.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Simple linear regression demonstrated a moderate influence of CR on single and DT walking speed in iNPH-P (\u03b2\u2009&gt;\u20090.3, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) but not in HC where the relation was not significant. In iNPH-P, results showed that CR played a major role in explaining each of the single and DT walking speeds with NPH-scale.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>As CR could be improved through the life cycle, these results support the idea of developing and supporting physical activity programs that will enrich social, physical, and cognitive resources to protect against age-related functional decline, especially in iNPH-P patients where the age-related deficits are greater.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s40520-024-02829-0","type":"journal-article","created":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T07:02:39Z","timestamp":1726038159000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The contribution of cognitive reserve in explaining the dual-task walking performance in iNPH patients: comparison with other cognitive, functional, and socio-demographic variables"],"prefix":"10.1007","volume":"36","author":[{"given":"Elodie","family":"Piche","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephane","family":"Armand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Allali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic","family":"Assal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,11]]},"reference":[{"key":"2829_CR1","doi-asserted-by":"publisher","first-page":"S24","DOI":"10.1227\/01.NEU.0000168185.29659.C5","volume":"57","author":"N Relkin","year":"2005","unstructured":"Relkin N, Marmarou A, Klinge P, Bergsneider M, McL Black P (2005) Diagnosing idiopathic normal-pressure hydrocephalus. 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