{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T03:38:40Z","timestamp":1775187520570,"version":"3.50.1"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,19]],"date-time":"2025-07-19T00:00:00Z","timestamp":1752883200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,7,19]],"date-time":"2025-07-19T00:00:00Z","timestamp":1752883200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Aging Clin Exp Res"],"DOI":"10.1007\/s40520-025-03108-2","type":"journal-article","created":{"date-parts":[[2025,7,19]],"date-time":"2025-07-19T08:00:28Z","timestamp":1752912028000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Admission reasons, procedures, and mortality of elderly patients in CICU: the SAGE-CICU study (study on acute gaps in the elderly - cardiac intensive care unit)"],"prefix":"10.1007","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-1593-5978","authenticated-orcid":false,"given":"Simone","family":"Filomia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluigi","family":"Saponara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco Giuseppe","family":"Del Buono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessia","family":"d\u2019Aiello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mattia","family":"Brecciaroli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Pedicino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rocco","family":"Montone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaetano","family":"Pinnacchio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenzo","family":"Genuardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacopo","family":"Lenkowicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierluigi","family":"Rogati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Trani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanna","family":"Liuzzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Burzotta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tommaso","family":"Sanna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,7,19]]},"reference":[{"issue":"6","key":"3108_CR1","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1056\/NEJMra2301292","volume":"391","author":"DH Kim","year":"2024","unstructured":"Kim DH, Rockwood K (2024) Title of the Article. N Engl J Med 391(6):538\u2013548","journal-title":"N Engl J Med"},{"issue":"20","key":"3108_CR2","doi-asserted-by":"publisher","first-page":"2419","DOI":"10.1016\/j.jacc.2016.03.004","volume":"67","author":"MW Rich","year":"2016","unstructured":"Rich MW, Chyun DA, Skolnick AH et al (2016) Knowledge gaps in cardiovascular care of the older adult population: A scientific statement from the American heart association, American college of cardiology, and American geriatrics society. J Am Coll Cardiol 67(20):2419\u20132440","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"3108_CR3","doi-asserted-by":"publisher","first-page":"e6","DOI":"10.1161\/CIR.0000000000000741","volume":"141","author":"AA Damluji","year":"2020","unstructured":"Damluji AA, Forman DE, van Diepen S et al (2020) Older adults in the cardiac intensive care unit: factoring geriatric syndromes in the management, prognosis, and process of care: A scientific statement from the American heart association. Circulation 141(2):e6\u2013e13","journal-title":"Circulation"},{"issue":"3","key":"3108_CR4","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1111\/jgs.17011","volume":"69","author":"L Ferrucci","year":"2021","unstructured":"Ferrucci L, Kuchel GA (2021) Heterogeneity of aging: individual risk factors, mechanisms, patient priorities, and outcomes. J Am Geriatr Soc 69(3):610\u2013612","journal-title":"J Am Geriatr Soc"},{"issue":"9","key":"3108_CR5","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1001\/jamacardio.2019.2467","volume":"4","author":"EA Bohula","year":"2019","unstructured":"Bohula EA, Katz JN, van Diepen S et al (2019) Demographics, care patterns, and outcomes of patients admitted to cardiac intensive care units: the critical care cardiology trials network prospective North American multicenter registry of cardiac critical illness. JAMA Cardiol 4(9):928\u2013935","journal-title":"JAMA Cardiol"},{"issue":"3","key":"3108_CR6","doi-asserted-by":"publisher","first-page":"165","DOI":"10.2459\/JCM.0b013e3283515be3","volume":"13","author":"G Casella","year":"2012","unstructured":"Casella G, Scorcu G, Cassin M et al (2012) Elderly patients with acute coronary syndromes admitted to Italian intensive cardiac care units: A Blitz-3 registry Sub-analysis. J Cardiovasc Med (Hagerstown) 13(3):165\u2013174","journal-title":"J Cardiovasc Med (Hagerstown)"},{"issue":"18","key":"3108_CR7","doi-asserted-by":"publisher","first-page":"1673","DOI":"10.1056\/NEJMoa2407791","volume":"391","author":"V Kunadian","year":"2024","unstructured":"Kunadian V, Mossop H, Shields C et al (2024) Invasive treatment strategy for older patients with myocardial infarction. N Engl J Med 391(18):1673\u20131684","journal-title":"N Engl J Med"},{"issue":"10","key":"3108_CR8","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1056\/NEJMoa2300468","volume":"389","author":"S Biscaglia","year":"2023","unstructured":"Biscaglia S, Guiducci V, Escaned J et al (2023) Complete or Culprit-Only PCI in older patients with myocardial infarction. N Engl J Med 389(10):889\u2013898","journal-title":"N Engl J Med"},{"issue":"2","key":"3108_CR9","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1097\/FJC.0000000000001584","volume":"84","author":"MG Buono Del","year":"2024","unstructured":"Del Buono MG, La Vecchia G, D\u2019Aiello A et al (2024) Clinical characteristics, management, and outcomes in cardiogenic shock: insights from a High-Volume Italian cardiac intensive care unit. J Cardiovasc Pharmacol 84(2):210\u2013219","journal-title":"J Cardiovasc Pharmacol"},{"key":"3108_CR10","doi-asserted-by":"publisher","first-page":"1869","DOI":"10.1016\/j.jacc.2020.02.057","volume":"75","author":"VL Cammann","year":"2020","unstructured":"Cammann VL, Szawan KA, St\u00e4hli BE et al (2020) Age-related variations in Takotsubo syndrome. J Am Coll Cardiol 75:1869\u20131877","journal-title":"J Am Coll Cardiol"},{"issue":"8","key":"3108_CR11","doi-asserted-by":"publisher","first-page":"929","DOI":"10.4244\/EIJV8I8A142","volume":"8","author":"J Ruiz-Garc\u00eda","year":"2012","unstructured":"Ruiz-Garc\u00eda J, Lerman A, Weisz G, Maehara A, Mintz GS, Fahy M, Xu K, Lansky AJ, Cristea E, Farah TG, Teles R, Botker HE, Templin B, Zhang Z, de Bruyne B, Serruys PW, Stone GW (2012) Age- and gender-related changes in plaque composition in patients with acute coronary syndrome: the PROSPECT study. EuroIntervention 8(8):929\u2013938","journal-title":"EuroIntervention"},{"issue":"2","key":"3108_CR12","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.jcmg.2023.05.011","volume":"17","author":"G Tzimas","year":"2024","unstructured":"Tzimas G, Gulsin GS, Everett RJ, Akodad M, Meier D, Sewnarain K, Ally Z, Alnamasy R, Ng N, Mullen S, Rotzinger D, Sathananthan J, Sellers SL, Blanke P, Leipsic JA (2024) Age- and Sex-Specific nomographic CT quantitative plaque data from a large international cohort. JACC Cardiovasc Imaging 17(2):165\u2013175","journal-title":"JACC Cardiovasc Imaging"},{"issue":"3","key":"3108_CR13","first-page":"242","volume":"8","author":"A Ariza-Sol\u00e9","year":"2019","unstructured":"Ariza-Sol\u00e9 A, Alegre O, Elola FJ, Fern\u00e1ndez C, Formiga F, Mart\u00ednez-Sell\u00e9s M, Bernal JL, Segura JV, I\u00f1\u00edguez A, Bertomeu V, Salazar-Mendiguch\u00eda J, S\u00e1nchez Salado JC, Lorente V, Cequier A (2019) Management of myocardial infarction in the elderly. Insights from Spanish minimum basic data set. Eur Heart J Acute Cardiovasc Care 8(3):242\u2013251","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"issue":"7","key":"3108_CR14","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.1111\/jgs.15383","volume":"66","author":"J Turk","year":"2018","unstructured":"Turk J, Fourny M, Yayehd K et al (2018) Age-Related differences in reperfusion therapy and outcomes for ST-Segment elevation myocardial infarction. J Am Geriatr Soc 66(7):1325\u20131331","journal-title":"J Am Geriatr Soc"},{"issue":"3","key":"3108_CR15","doi-asserted-by":"publisher","first-page":"e32","DOI":"10.1161\/CIR.0000000000001112","volume":"147","author":"AA Damluji","year":"2023","unstructured":"Damluji AA, Forman DE, Wang TY et al (2023) Management of acute coronary syndrome in the older adult population: A scientific statement from the American heart association. Circulation 147(3):e32\u2013e62","journal-title":"Circulation"},{"issue":"8 Suppl","key":"3108_CR16","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1016\/S0735-1097(23)01119-1","volume":"81","author":"M Martillo","year":"2023","unstructured":"Martillo M, Olarte N, Ebner B et al (2023) Survival of elderly patients using temporary mechanical circulatory support. J Am Coll Cardiol 81(8 Suppl):675","journal-title":"J Am Coll Cardiol"},{"issue":"12 Suppl 3","key":"3108_CR17","doi-asserted-by":"publisher","first-page":"47","DOI":"10.3949\/ccjm.84.s3.05","volume":"84","author":"CT Lambert","year":"2017","unstructured":"Lambert CT, Tarakji KG (2017) Cardiac implantable electronic device infection. Cleve Clin J Med 84(12 Suppl 3):47\u201353","journal-title":"Cleve Clin J Med"},{"issue":"2","key":"3108_CR18","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.jacc.2021.10.037","volume":"79","author":"AS Volgman","year":"2022","unstructured":"Volgman AS, Nair G, Lyubarova R et al (2022) Management of atrial fibrillation in patients 75 years and older: JACC State-of-the-Art review. J Am Coll Cardiol 79(2):166\u2013179","journal-title":"J Am Coll Cardiol"},{"issue":"11","key":"3108_CR19","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1016\/j.jacc.2013.05.015","volume":"62","author":"RL Osnabrugge","year":"2013","unstructured":"Osnabrugge RL, Mylotte D, Head SJ et al (2013) Aortic stenosis in the elderly: disease prevalence and number of candidates for transcatheter aortic valve replacement: A Meta-analysis and modeling study. J Am Coll Cardiol 62(11):1002\u20131012","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"3108_CR20","doi-asserted-by":"publisher","first-page":"100877","DOI":"10.1016\/j.jacadv.2024.100877","volume":"3","author":"AA Damluji","year":"2024","unstructured":"Damluji AA, Bernacki G, Afilalo J et al (2024) TAVR in older adults: moving toward a comprehensive geriatric assessment and away from chronological age: JACC family series. JACC Adv 3(4):100877","journal-title":"JACC Adv"},{"issue":"21","key":"3108_CR21","doi-asserted-by":"publisher","first-page":"1949","DOI":"10.1056\/NEJMoa2307447","volume":"389","author":"MJ Mack","year":"2023","unstructured":"Mack MJ, Leon MB, Thourani VH et al (2023) Transcatheter Aortic-Valve replacement in Low-Risk patients at five years. N Engl J Med 389(21):1949\u20131960","journal-title":"N Engl J Med"},{"issue":"4","key":"3108_CR22","doi-asserted-by":"publisher","first-page":"101002","DOI":"10.1016\/j.jscai.2023.101002","volume":"2","author":"J Zhong","year":"2023","unstructured":"Zhong J, Kamp N, Bansal A et al (2023) Balloon aortic valvuloplasty in the modern era: A review of outcomes, indications, and technical advances. J Soc Cardiovasc Angiography Interventions 2(4):101002","journal-title":"J Soc Cardiovasc Angiography Interventions"},{"issue":"14","key":"3108_CR23","doi-asserted-by":"publisher","first-page":"e1051","DOI":"10.1161\/CIR.0000000000001214","volume":"149","author":"V Blumer","year":"2024","unstructured":"Blumer V, Kanwar MK, Barnett CF et al (2024) Cardiogenic shock in older adults: A focus on Age-Associated risks and approach to management: A scientific statement from the American heart association. Circulation 149(14):e1051\u2013e1065","journal-title":"Circulation"},{"issue":"5","key":"3108_CR24","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1016\/j.ahj.2014.01.013","volume":"167","author":"MA Velders","year":"2014","unstructured":"Velders MA, James SK, Libungan B et al (2014) Prognosis of elderly patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention in 2001 to 2011: A report from the Swedish coronary angiography and angioplasty registry (SCAAR). Am Heart J 167(5):666\u2013673","journal-title":"Am Heart J"},{"issue":"4","key":"3108_CR25","doi-asserted-by":"publisher","first-page":"e030623","DOI":"10.1161\/JAHA.123.030623","volume":"13","author":"I El-Battrawy","year":"2024","unstructured":"El-Battrawy I, Santoro F, N\u00fa\u00f1ez-Gil IJ et al (2024) Age-Related differences in Takotsubo syndrome: results from the multicenter GEIST registry. J Am Heart Association 13(4):e030623","journal-title":"J Am Heart Association"},{"issue":"2","key":"3108_CR26","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1111\/jgs.13276","volume":"63","author":"IJ N\u00fa\u00f1ez-Gil","year":"2015","unstructured":"N\u00fa\u00f1ez-Gil IJ, Sionis A, Andr\u00e9s M et al (2015) Takotsubo cardiomyopathy and elderly adults: still a benign condition? J Am Geriatr Soc 63(2):404\u2013407","journal-title":"J Am Geriatr Soc"}],"container-title":["Aging Clinical and Experimental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40520-025-03108-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40520-025-03108-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40520-025-03108-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T01:02:31Z","timestamp":1757984551000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40520-025-03108-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,19]]},"references-count":26,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["3108"],"URL":"https:\/\/doi.org\/10.1007\/s40520-025-03108-2","relation":{},"ISSN":["1720-8319"],"issn-type":[{"value":"1720-8319","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,19]]},"assertion":[{"value":"14 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 September 2025","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The original article has been updated to update the error in the XML tagging of the author name  Del Buono  Marco Giuseppe.","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"224"}}