{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T14:13:40Z","timestamp":1790864020006,"version":"4.1.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T00:00:00Z","timestamp":1766966400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T00:00:00Z","timestamp":1766966400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Aging Clin Exp Res"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Measuring hand grip strength (HGS) at admission can indicate probable sarcopenia in acute hip fracture and may help predict adverse post-operative outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To assess whether HGS is independently associated with adverse post-operative outcomes and enhances risk prediction when combined with the Nottingham Hip Fracture Score (NHFS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Routinely collected National Hip Fracture Database data were combined with HGS at a single, high-volume orthopaedic trauma centre. Sarcopenia status was categorised per 2019 European Working Group thresholds as non-sarcopenic, probable sarcopenia, or unable to complete assessment. Binary logistic regression models and receiver-operating-characteristic (ROC) curves assessed prognostic value of HGS assessment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We analysed data from 282 patients, mean age 83.2\u2009\u00b1\u20099.2 years; 200 (71%) were women. In univariate analysis, probable sarcopenia (low HGS) was associated with 120-day mortality, 30- and 120-day residential status, prolonged length of stay and post-operative delirium. In multivariate analysis including the NHFS, probable sarcopenia was associated with 120-day mortality, 120-day residential status and post-operative delirium. Combining NHFS and HGS assessment improved discrimination for 120-day mortality (c-statistic 0.79 [95%CI 0.73\u20130.86]), 30-day residential status (0.85 [95%CI 0.80\u20130.90]) 120-day residential status (0.89 [95% CI 0.85\u20130.94]) and post-operative delirium (0.91 [95%CI 0.87\u20130.94]). Inability to complete HGS assessment was associated with worse prognostic outcomes than low HGS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Sarcopenia is a useful additional predictor of post-operative outcomes in hip fracture, especially post-operative delirium. Inability to complete HGS assessment may indicate even higher risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>HGS is an inexpensive, feasible and quick adjunct to the NHFS. Further research is required to validate a combined NHFS-HGS score.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s40520-025-03262-7","type":"journal-article","created":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T13:43:37Z","timestamp":1767015817000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Sarcopenia status as assessed by hand grip strength enhances prediction of post-operative outcomes in hip fracture patients"],"prefix":"10.1007","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3564-8464","authenticated-orcid":false,"given":"James","family":"Prowse","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharlene","family":"Jaiswal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Chaplin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Langford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avan A.","family":"Sayer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Sinclair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike R.","family":"Reed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miles D.","family":"Witham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antony K.","family":"Sorial","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,29]]},"reference":[{"key":"3262_CR1","doi-asserted-by":"publisher","first-page":"1064","DOI":"10.1002\/jbmr.4821","volume":"38","author":"C-W Sing","year":"2023","unstructured":"Sing C-W, Lin T-C, Bartholomew S et al (2023) Global epidemiology of hip fractures: secular trends in incidence rate, post-fracture treatment, and all-cause mortality. 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MDW, AAS, SJ and JP acknowledge support from the NIHR Newcastle Biomedical Research Centre. No external funding was used to conduct this work. AKS received project support from Newcastle University MRes programme and salary funding from the NIHR integrated academic training programme. MRR reports grants from Vifor Pharma, Heraeus Medical GMBH, Zimmer Biomet, 3\u00a0M, OpGen Inc, Schuelke, Stryker, Biocomposites, Aquilant, Depuy, and Smith and Nephew; speaker fees from Heraeus, Zimmer Biomet and Stryker. AC, SL and NS have nothing to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}],"article-number":"9"}}