{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T23:53:47Z","timestamp":1781826827990,"version":"3.54.5"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T00:00:00Z","timestamp":1781827200000},"content-version":"vor","delay-in-days":51,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100016003","name":"Mie University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100016003","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Aging Clin Exp Res"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Older patients with inflammatory bowel disease (IBD) often have multimorbidity and functional vulnerability, which increases the risk of in-hospital complications. This study examined whether frailty at admission is associated with hospital-associated geriatric complications in this population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study was conducted using a nationwide hospital-based claims database in Japan. Patients aged\u2009\u2265\u200960 years hospitalized with ulcerative colitis or Crohn\u2019s disease between February 2014 and September 2025 were identified. Frailty was assessed using the Hospital Frailty Risk Score (HFRS\u2009\u2265\u20095). The primary outcome was hospital-associated complications in older people (HAC-OP), which is a composite of functional decline, incontinence, delirium, pressure injury, and falls\/fractures. The risk ratios (RRs) and 95% confidence intervals (CIs) were estimated using modified Poisson regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 3,905 hospitalizations, 1,220 (31.2%) patients were classified as frail. Overall, 6.7% of hospitalizations were complicated by at least one HAC-OP, with a higher incidence in patients with frailty than in non-frail patients (10.7% vs. 4.8%). Frailty was associated with HAC-OP (adjusted RR 1.74, 95% CI 1.36\u20132.21), functional decline (adjusted RR 1.54, 95% CI 1.12\u20132.11), and delirium (adjusted RR 2.50, 95% CI 1.66\u20133.76). Results were robust in sensitivity analyses using multiple imputation, additional adjustment for length of stay.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In hospitalized older patients with IBD, frailty at admission was associated with hospital-associated geriatric complications, particularly delirium and functional decline. The HFRS may be a useful tool for identifying patients at higher risk, and future studies should evaluate whether frailty-targeted interventions can reduce these complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s40520-026-03390-8","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T05:36:50Z","timestamp":1777441010000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Frailty and geriatric complications in older patients with IBD: a nationwide hospital claims database study across Japan"],"prefix":"10.1007","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0244-1953","authenticated-orcid":false,"given":"Akio","family":"Shimizu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3610-1025","authenticated-orcid":false,"given":"Akira","family":"Horiuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4189-5245","authenticated-orcid":false,"given":"Yasutake","family":"Tomata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1753-4450","authenticated-orcid":false,"given":"Shintaro","family":"Togashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ichitaro","family":"Horiuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0357-8604","authenticated-orcid":false,"given":"Naoharu","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3274-3952","authenticated-orcid":false,"given":"Ryo","family":"Momosaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,29]]},"reference":[{"key":"3390_CR1","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1016\/S2468-1253(22)00358-2","volume":"8","author":"S Singh","year":"2023","unstructured":"Singh S, Boland BS, Jess T, Moore AA (2023) Management of inflammatory bowel diseases in older adults. 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