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This study investigated the bidirectional association of LoS and sarcopenia indices (lean soft tissue, muscle strength, physical function) in older inpatients, with a focus on age- and sex-specific differences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using cross-sectional data from the Copenhagen PROTECT study, 1071 older inpatients (aged\u2009\u2265\u200965 years) were included. Appendicular lean soft tissue index (ALSTI), handgrip strength (HGS), gait speed, and 30-second chair stand test (30CST) were assessed within 24\u00a0h of admission and sarcopenia was defined per the EWGSOP2 criteria. Linear and logistic regressions examined associations between LoS and sarcopenia indices, stratified by age and sex.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In patients\u2009\u2265\u200980 years, longer LoS (based on the cohort\u2019s median) was associated with lower gait speed and 30CST in both sexes (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01), and lower HGS in women (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03). In men\u2009&lt;\u200980 years, longer LoS correlated with lower HGS and 30CST (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01), with higher odds of sarcopenia (Low ALSTI and low 30CST; OR\u2009=\u20093.14,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03). Higher 30CST and HGS were consistently associated with shorter LoS, particularly in men\u2009\u2265\u200980 years and women across both age groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>HGS and 30CST are strongly associated with LoS in older inpatients, with more pronounced effects in those\u2009\u2265\u200980 years. Future longitudinal studies and trials are warranted to confirm causality, that may guide rehabilitation strategies to reduce LoS through targeted interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s40520-026-03442-z","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T10:35:04Z","timestamp":1782383704000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Associations of length of stay with sarcopenia parameters in geriatric patients: age and sex differences in the oldest old"],"prefix":"10.1007","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6264-9388","authenticated-orcid":false,"given":"Konstantinos","family":"Prokopidis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanne","family":"Nygaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rikke S","family":"Kamper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pernille","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofie K","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eckart","family":"Pressel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Rasmussen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Suetta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,25]]},"reference":[{"issue":"11","key":"3442_CR1","doi-asserted-by":"publisher","first-page":"afae241","DOI":"10.1093\/ageing\/afae241","volume":"53","author":"C Welch","year":"2024","unstructured":"Welch C, Chen Y, Hartley P, Naughton C, Martinez-Velilla N, Stein D, Romero-Ortuno R (2024) New horizons in hospital-associated deconditioning: a global condition of body and mind. 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