{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T20:31:21Z","timestamp":1790195481305,"version":"4.1.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T00:00:00Z","timestamp":1718668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T00:00:00Z","timestamp":1718668800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100012544","name":"China Medical University, Taiwan","doi-asserted-by":"publisher","award":["CMU112\u2013MF\u201376 and CMU111\u2013MF\u201382"],"award-info":[{"award-number":["CMU112\u2013MF\u201376 and CMU111\u2013MF\u201382"]}],"id":[{"id":"10.13039\/501100012544","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012544","name":"China Medical University, Taiwan","doi-asserted-by":"publisher","award":["CMU112\u2013MF\u201376 and CMU111\u2013MF\u201382"],"award-info":[{"award-number":["CMU112\u2013MF\u201376 and CMU111\u2013MF\u201382"]}],"id":[{"id":"10.13039\/501100012544","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Science and Technology Council, Taiwan","award":["111\u20132314\u2013B\u2013039\u2013020\u2013MY2 and 110\u20132314\u2013B\u2013039\u2013058"],"award-info":[{"award-number":["111\u20132314\u2013B\u2013039\u2013020\u2013MY2 and 110\u20132314\u2013B\u2013039\u2013058"]}]},{"name":"National Science and Technology Council, Taiwan","award":["111\u20132314\u2013B\u2013039\u2013020\u2013MY2 and 110\u20132314\u2013B\u2013039\u2013058"],"award-info":[{"award-number":["111\u20132314\u2013B\u2013039\u2013020\u2013MY2 and 110\u20132314\u2013B\u2013039\u2013058"]}]},{"name":"National Science and Technology Council, Taiwan","award":["111\u20132314\u2013B\u2013039\u2013020\u2013MY2 and 110\u20132314\u2013B\u2013039\u2013058"],"award-info":[{"award-number":["111\u20132314\u2013B\u2013039\u2013020\u2013MY2 and 110\u20132314\u2013B\u2013039\u2013058"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Envir Health Rpt"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose of Review<\/jats:title>\n                <jats:p>Numerous epidemiological studies have shown increased health risks among workers and residents living near nuclear power plants exposed to radiation levels meeting regulatory dose limits. This study aimed to evaluate the association between radiation exposure and disease risks among these populations exposed to radiation levels meeting the current regulatory dose limits.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Recent Findings<\/jats:title>\n                <jats:p>We searched four databases (Cochrane Library, PubMed, ScienceDirect, and Web of Science) for studies published before August 2023, screened eligible studies (inclusion and exclusion criteria based on population, exposure, comparator, and outcome framework), and collected data on exposure indicators and disease risks. We applied random-effects models of meta-analysis to estimate the pooled effects and meta-regression to assess the dose-response relationship (radiation dose rate for workers and distance for residents). We identified 47 studies, 13 with worker and 34 with resident samples, covering 175 nuclear power plants from 17 countries, encompassing samples of 480,623 workers and 7,530,886 residents. Workers had a significantly lower risk for all-cancer and a significantly higher risk for mesothelioma. Residents had significantly higher risks for all-cancer, thyroid cancer, and leukemia. Notably, children under 5 years old showed the highest risk for all-cancer. Our meta-regression showed a significantly positive dose-response relationship between cumulative dose of radiation exposure and risk for circulatory disease among workers.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Summary<\/jats:title>\n                <jats:p>Our findings demonstrated higher risks for mesothelioma for workers and all-cancer, thyroid cancer, and leukemia for residents exposed to low-dose radiation from nuclear power plants. Some included studies did not adjust for cancer risk confounders, which could overestimate the association between radiation exposure and cancer risk and increase the risk of bias.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s40572-024-00453-8","type":"journal-article","created":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T00:01:57Z","timestamp":1718668917000},"page":"329-339","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Health Effects of Occupational and Environmental Exposures to Nuclear Power Plants: A Meta-Analysis and Meta-Regression"],"prefix":"10.1007","volume":"11","author":[{"given":"Ro-Ting","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hathaichon","family":"Boonhat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Yu","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonja","family":"Klebe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,18]]},"reference":[{"key":"453_CR1","volume-title":"Analysis of cancer risks in populations near nuclear facilities: phase 1","author":"National Research Council","year":"2012","unstructured":"National Research Council. Analysis of cancer risks in populations near nuclear facilities: phase 1. Washington, DC: National Academies; 2012."},{"key":"453_CR2","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1007\/s00204-009-0412-4","volume":"83","author":"EJ Calabrese","year":"2009","unstructured":"Calabrese EJ. The road to linearity: why linearity at low doses became the basis for carcinogen risk assessment. Arch Toxicol. 2009;83:203\u201325.","journal-title":"Arch Toxicol"},{"key":"453_CR3","first-page":"1","volume":"37","author":"International Commission on Radiological Protection (ICRP)","year":"2007","unstructured":"International Commission on Radiological Protection (ICRP). The 2007 recommendations of the International Commission on Radiological Protection. ICRP publication 103. 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