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Racial and Ethnic Health Disparities"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>COVID-19 mortality studies have primarily focused on persons aged \u2265 65 years; less is known about decedents aged &lt;65 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a case-control study among NYC residents aged 21\u201364 years hospitalized with COVID-19 diagnosed March 13\u2013April 9, 2020, to determine risk factors for death. Case-patients (n=343) were hospitalized decedents with COVID-19 and control-patients (n=686) were discharged from hospitalization with COVID-19 and matched 2:1 to case-patients on age and residential neighborhood. Conditional logistic regression models were adjusted for patient sex, insurance status, and marital status. Matched adjusted odds ratios (aORs) were calculated for selected underlying conditions, combinations of conditions, and race\/ethnic group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Median age of both case-patients and control-patients was 56 years (range: 23\u201364 years). Having \u2265 1 selected underlying condition increased odds of death 4.45-fold (95% CI: 2.33\u20138.49). Patients with diabetes; morbid obesity; heart, kidney, or lung disease; cancer; neurologic\/neurodevelopmental conditions; mental health conditions; or HIV had significantly increased odds of death. Compared with having neither condition, having both diabetes and obesity or diabetes and heart disease was associated with approximately threefold odds of death. Five select underlying conditions were more prevalent among non-Hispanic Black control-patients than among control-patients of other races\/ethnicities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Relevance<\/jats:title>\n                    <jats:p>Selected underlying conditions were risk factors for death, and most prevalent among racial\/ethnic minorities. Social services; health care resources, including vaccination; and tailored public health messaging are important for COVID-19 prevention. Strengthening these strategies for racial\/ethnic minority groups could minimize COVID-19 racial\/ethnic disparities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s40615-021-01098-1","type":"journal-article","created":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T17:02:45Z","timestamp":1628528565000},"page":"1584-1599","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Risk Factors for Death Among Hospitalized Patients Aged 21\u201364 Years Diagnosed with COVID-19\u2014New York City, March 13\u2013April 9, 2020"],"prefix":"10.1007","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9519-5071","authenticated-orcid":false,"given":"Dena","family":"Bushman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Davidson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Preeti","family":"Pathela","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon K.","family":"Greene","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Don","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasudha","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"New York City Fatal Case-Control St","family":"Team","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Latash","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,8,9]]},"reference":[{"issue":"46","key":"1098_CR1","doi-asserted-by":"publisher","first-page":"1725","DOI":"10.15585\/mmwr.mm6946a2","volume":"69","author":"CN Thompson","year":"2020","unstructured":"Thompson CN, Baumgartner J, Pichardo C, Toro B, Li L, Arciuolo R, et al. 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The DOHMH Institutional Review Board determined this activity to be non-research public health surveillance.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Not applicable","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"Not applicable","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"The findings and conclusions in the article are those of the authors and do not necessarily represent the official position of the U.S. Centers for Disease Control and Prevention (CDC).","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclaimer"}}]}}