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Racial and Ethnic Health Disparities"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Incidence of endometrial cancer (EC) in Hispanic\/Latina (H\/L) women are higher compared to other race\/ethnicities in the United States. EC is the third most common cancer and the fourth cause of cancer-related deaths in Puerto Rican women, yet demographic and clinical information is limited. High rates of EC risk factors such as obesity, diabetes mellitus type 2 (DM2) and hypertension (HTN) have been documented in the Puerto Rican population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe the demographic, clinical history, lifestyle, obstetrical-gynecological, pathologic, and molecular profiles of women with EC predominantly from Southern\/Central Puerto Rico.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective secondary analysis of data abstracted from the Puerto Rico Central Cancer Registry (PRCCR), self-administered questionnaires and medical records of EC cases. Descriptive statistics were conducted using SPSS V28 and RStudio.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We identified 105 EC cases aged 28\u201382. The major risk factors were BMI\u2009\u2265\u200930 (72%), HTN (33%), and DM2 (20%). Endometrioid adenocarcinoma was the main histological tumor type (80%), of which 74% were Type I. Obesity and nulliparity were associated with younger age at diagnosis. Older age at diagnosis (&gt;\u200965 y\/o) was associated with more advanced disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study defined the clinical-demographic profile of women with EC from Puerto Rico and identified risks factors that are associated with younger or older age at diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Impact<\/jats:title>\n                    <jats:p>Profiling the risk factors for EC may help improve diagnostic accuracy and clinical management and result in better outcomes for this under-served, under-researched cancer patient population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s40615-024-02267-8","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T13:26:14Z","timestamp":1737379574000},"page":"552-561","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Profiling Sociodemographic Risk Factors and Clinical Outcomes of Women with Endometrial Cancer in Puerto Rico: The Central Role of Obesity and Obstetric Features"],"prefix":"10.1007","volume":"13","author":[{"given":"Kimberly D.","family":"Garc\u00eda-Irizarry","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda E.","family":"Rojas-Brenes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 A.","family":"Oliveras-Torres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila N.","family":"Ortiz-Ortiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William D.","family":"Cress","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edna","family":"Gordi\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo G\u00f3mez","family":"Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco J.","family":"Quintana-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro F.","family":"Escobar-Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresita","family":"Mu\u00f1oz-Antonia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2130-4508","authenticated-orcid":false,"given":"Idhaliz","family":"Flores","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,1,20]]},"reference":[{"key":"2267_CR1","unstructured":"USCS Data Visualizations - CDC [Internet]. 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