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Racial and Ethnic Health Disparities"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    North American Indigenous (NAI) adolescents experience disproportionately high rates of alcohol-related consequences and racial discrimination but report similar rates of alcohol consumption as other racial\/ethnic groups. Racial discrimination serves a deleterious role on adolescent development and well-being. To test if NAI adolescents\u2019 disproportionate rates of alcohol-related consequences are related to the negative effects of racial discrimination, the present study examined whether racial discrimination moderates the association between alcohol consumption and alcohol-related consequences among NAI adolescents. Participants were First Nations adolescents from reserve communities in Eastern Canada (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200960,\n                    <jats:italic>M<\/jats:italic>\n                    <jats:sub>\n                      <jats:italic>age<\/jats:italic>\n                    <\/jats:sub>\n                    \u2009=\u200915.9, 53.3% female) who reported lifetime alcohol use. The interaction of alcohol consumption by racial discrimination was statistically significantly and positively associated with alcohol-related consequences (\n                    <jats:italic>b<\/jats:italic>\n                    \u2009=\u20091.28,\n                    <jats:italic>SE<\/jats:italic>\n                    \u2009=\u20090.56,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u2009.025). Simple slopes analyses revealed that alcohol consumption was significantly positively related to alcohol-related consequences for those reporting high levels of racial discrimination (1\n                    <jats:italic>SD<\/jats:italic>\n                    above the mean;\n                    <jats:italic>b<\/jats:italic>\n                    \u2009=\u20091.19,\n                    <jats:italic>SE<\/jats:italic>\n                    \u2009=\u20090.27,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u2009.001), but not for those reporting relatively low levels of racial discrimination (1\n                    <jats:italic>SD<\/jats:italic>\n                    below the mean). Thus, racial discrimination may contribute to the disproportionate rate of consequences related to alcohol consumption experienced by NAI adolescents. These findings suggest the need for systems-level interventions to address racial discrimination and prejudice, as well as individual-focused interventions to increase factors previously found to protect against the negative effects of racial discrimination (e.g., racial-ethnic socialization, self-compassion).\n                  <\/jats:p>","DOI":"10.1007\/s40615-025-02637-w","type":"journal-article","created":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T19:42:38Z","timestamp":1785354158000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Racial Discrimination Moderates the Association Between Alcohol Consumption and Alcohol-Related Consequences Among One First Nation Reserve Community\u2019s Youth"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1332-195X","authenticated-orcid":false,"given":"Tessa","family":"Nalven","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0689-6672","authenticated-orcid":false,"given":"Melissa R.","family":"Schick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4110-3255","authenticated-orcid":false,"given":"Nichea S.","family":"Spillane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,29]]},"reference":[{"issue":"1","key":"2637_CR1","doi-asserted-by":"publisher","first-page":"e180382","DOI":"10.1001\/jamanetworkopen.2018.0382","volume":"1","author":"RC Swaim","year":"2018","unstructured":"Swaim RC, Stanley LR. 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Approval was granted by the University of Rhode Island Institutional Review Board (IRB Reference #: 853429).","order":1,"name":"Ethics","label":"Ethics Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Assent was obtained from all adolescent participants included in the study and parental informed consent was obtained from the parents of each adolescent.","order":2,"name":"Ethics","label":"Consent to Participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}