{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:51:15Z","timestamp":1761519075980},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Endocrinol Invest"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1007\/s40618-013-0026-9","type":"journal-article","created":{"date-parts":[[2014,1,7]],"date-time":"2014-01-07T08:39:27Z","timestamp":1389083967000},"page":"71-77","source":"Crossref","is-referenced-by-count":12,"title":["Thyroid peroxidase autoantibodies are associated with a lesser likelihood of late reversion to hyperthyroidism after successful non-ablative treatment of Graves\u2019 disease in Croatian patients"],"prefix":"10.1007","volume":"37","author":[{"given":"M.","family":"Stefanic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Karner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,1,8]]},"reference":[{"key":"26_CR1","doi-asserted-by":"crossref","first-page":"3777","DOI":"10.1210\/jcem.83.11.5056-1","volume":"83","author":"TF Davies","year":"1998","unstructured":"Davies TF, Roti E, Braverman LE, DeGroot LJ (1998) Thyroid controversy-stimulating antibodies. J Clin Endocrinol Metab 83:3777\u20133785","journal-title":"J Clin Endocrinol Metab"},{"key":"26_CR2","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1146\/annurev.me.44.020193.001543","volume":"44","author":"U Feldt-Rasmussen","year":"1993","unstructured":"Feldt-Rasmussen U, Glinoer D, Orgiazzi J (1993) Reassessment of antithyroid drug therapy of Graves\u2019 disease. Annu Rev Med 44:323\u2013334","journal-title":"Annu Rev Med"},{"key":"26_CR3","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1136\/adc.52.12.951","volume":"52","author":"T Sato","year":"1997","unstructured":"Sato T, Takata I, Taketani T, Saida K, Nakajima H (1997) Concurrence of Grave\u2019s disease and Hashimoto\u2019s thyroiditis. Arch Dis Child 52:951\u2013955","journal-title":"Arch Dis Child"},{"key":"26_CR4","first-page":"939","volume":"77","author":"R Paschke","year":"1993","unstructured":"Paschke R, Vogg M, Swillens S, Usadel KH (1993) Correlation of microsomal antibodies with the intensity of the intrathyroidal autoimmune process in Graves\u2019 disease. J Clin Endocrinol Metab 77:939\u2013943","journal-title":"J Clin Endocrinol Metab"},{"key":"26_CR5","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1210\/er.2004-0023","volume":"26","author":"SM McLachlan","year":"2005","unstructured":"McLachlan SM, Nagayama Y, Rapoport B (2005) Insight into Graves\u2019 hyperthyroidism from animal models. Endocr Rev 26:800\u2013832","journal-title":"Endocr Rev"},{"key":"26_CR6","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1089\/thy.2006.16.1041","volume":"16","author":"I Guilhem","year":"2006","unstructured":"Guilhem I, Massart C, Poirier JY, Maugendre D (2006) Differential evolution of thyroid peroxidase and thyrotropin receptor antibodies in Graves\u2019 disease: thyroid peroxidase antibody activity reverts to pretreatment level after carbimazole withdrawal. Thyroid 16:1041\u20131045","journal-title":"Thyroid"},{"key":"26_CR7","doi-asserted-by":"crossref","first-page":"3817","DOI":"10.1210\/jc.2008-0842","volume":"93","author":"F Kaguelidou","year":"2008","unstructured":"Kaguelidou F, Alberti C, Castanet M et al (2008) Predictors of autoimmune hyperthyroidism relapse in children after discontinuation of antithyroid drug treatment. J Clin Endocrinol Metab 93:3817\u20133826","journal-title":"J Clin Endocrinol Metab"},{"key":"26_CR8","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1055\/s-2007-957347","volume":"39","author":"M Schott","year":"2007","unstructured":"Schott M, Eckstein A, Willenberg HS, Nguyen TB, Morgenthaler NG, Scherbaum WA (2007) Improved prediction of relapse of Graves\u2019 thyrotoxicosis by combined determination of TSH receptor and thyroperoxidase antibodies. Horm Metab Res 39:56\u201361","journal-title":"Horm Metab Res"},{"key":"26_CR9","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1530\/acta.0.1140328","volume":"114","author":"N Hamada","year":"1987","unstructured":"Hamada N, Ito K, Mimura T et al (1987) Retrospective reevaluation of the significance of thyroid microsomal antibody in the treatment of Graves\u2019 disease. Acta Endocrinol (Copenh) 114:328\u2013335","journal-title":"Acta Endocrinol (Copenh)"},{"key":"26_CR10","doi-asserted-by":"crossref","first-page":"167","DOI":"10.3109\/08916930008994089","volume":"32","author":"L Lavard","year":"2000","unstructured":"Lavard L, Perrild H, Jacobsen BB, H\u00f8ier-Madsen M, Bendinelli G, Vitti P (2000) Prevalence of thyroid peroxidase, thyroglobulin and thyrotropin receptor antibodies in a long-term follow-up of juvenile Graves disease. Autoimmunity 32:167\u2013172","journal-title":"Autoimmunity"},{"key":"26_CR11","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1210\/jcem-68-6-1097","volume":"68","author":"Y Takaichi","year":"1989","unstructured":"Takaichi Y, Tamai H, Honda K, Nagai K, Kuma K, Nakagawa T (1989) The significance of antithyroglobulin and antithyroidal microsomal antibodies in patients with hyperthyroidism due to Graves\u2019 disease treated with antithyroidal drugs. J Clin Endocrinol Metab 68:1097\u20131100","journal-title":"J Clin Endocrinol Metab"},{"key":"26_CR12","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1210\/jcem-62-1-165","volume":"62","author":"Y Hirota","year":"1986","unstructured":"Hirota Y, Tamai H, Hayashi Y et al (1986) Thyroid function and histology in forty-five patients with hyperthyroid Graves\u2019 disease in clinical remission more than ten years after thionamide drug treatment. J Clin Endocrinol Metab 62:165\u2013169","journal-title":"J Clin Endocrinol Metab"},{"key":"26_CR13","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1097\/01.smj.0000240120.89381.b2","volume":"99","author":"AV Moraes De","year":"2006","unstructured":"De Moraes AV, Pedro AB, Romaldini JH (2006) Spontaneous hypothyroidism in the follow up of Graves hyperthyroid patients treated with antithyroid drugs. South Med J 99:1068\u20131072","journal-title":"South Med J"},{"key":"26_CR14","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1210\/jcem-44-1-203","volume":"44","author":"SC Werner","year":"1977","unstructured":"Werner SC (1977) Modification of the classification of the eye changes of Graves\u2019 disease: recommendations of the Ad Hoc Committee of the American Thyroid Association. J Clin Endocrinol Metab 44:203\u2013204","journal-title":"J Clin Endocrinol Metab"},{"key":"26_CR15","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1007\/BF03347356","volume":"26","author":"Z Kusi\u0107","year":"2009","unstructured":"Kusi\u0107 Z, Novosel SA, Dabeli\u0107 N et al (2009) Croatia has reached iodine sufficiency. J Endocrinol Invest 26:738\u2013742","journal-title":"J Endocrinol Invest"},{"key":"26_CR16","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1530\/eje.0.1440475","volume":"144","author":"D Glinoer","year":"2001","unstructured":"Glinoer D, de Nayer P, Bex M, Belgian Collaborative Study Group on Graves\u2019 Disease (2001) Effects of l-thyroxine administration, TSH-receptor antibodies and smoking on the risk of recurrence in Graves\u2019 hyperthyroidism treated with antithyroid drugs: a double-blind prospective randomized study. Eur J Endocrinol 144:475\u2013483","journal-title":"Eur J Endocrinol"},{"key":"26_CR17","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1089\/thy.1997.7.369","volume":"7","author":"P Vitti","year":"1997","unstructured":"Vitti P, Rago T, Chiovato L et al (1997) Clinical features of patients with Graves\u2019 disease undergoing remission after antithyroid drug treatment. Thyroid 7:369\u2013375","journal-title":"Thyroid"},{"key":"26_CR18","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1089\/thy.2005.15.1047","volume":"15","author":"B Quadbeck","year":"2005","unstructured":"Quadbeck B, Hoermann R, Roggenbuck U et al (2005) Sensitive thyrotropin and thyrotropin-receptor antibody determinations one month after discontinuation of antithyroid drug treatment as predictors of relapse in Graves\u2019 disease. Thyroid 15:1047\u20131054","journal-title":"Thyroid"},{"key":"26_CR19","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1038\/nri750","volume":"2","author":"G Stassi","year":"2002","unstructured":"Stassi G, De Maria R (2002) Autoimmune thyroid disease: new models of cell death in autoimmunity. Nat Rev Immunol 2:195\u2013204","journal-title":"Nat Rev Immunol"},{"key":"26_CR20","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1089\/thy.2007.0169","volume":"17","author":"SM McLachlan","year":"2007","unstructured":"McLachlan SM, Rapoport B (2007) Thyroid peroxidase as an autoantigen. Thyroid 17:939\u2013948","journal-title":"Thyroid"},{"key":"26_CR21","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3109\/08916939708996272","volume":"25","author":"RA Metcalfe","year":"1997","unstructured":"Metcalfe RA, Oh YS, Stroud C, Arnold K, Weetman AP (1997) Analysis of antibody-dependent cell-mediated cytotoxicity in autoimmune thyroid disease. Autoimmunity 25:65\u201372","journal-title":"Autoimmunity"},{"key":"26_CR22","first-page":"2595","volume":"81","author":"P Rodien","year":"1996","unstructured":"Rodien P, Madec AM, Ruf J et al (1996) Antibody-dependent cell-mediated cytotoxicity in autoimmune thyroid disease: relationship to antithyroperoxidase antibodies. J Clin Endocrinol Metab 81:2595\u20132600","journal-title":"J Clin Endocrinol Metab"},{"key":"26_CR23","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1089\/thy.2012.0374","volume":"23","author":"SM McLachlan","year":"2013","unstructured":"McLachlan SM, Rapoport B (2013) Thyrotropin-blocking autoantibodies and thyroid-stimulating autoantibodies: potential mechanisms involved in the pendulum swinging from hypothyroidism to hyperthyroidism or vice versa. Thyroid 23:14\u201324","journal-title":"Thyroid"},{"key":"26_CR24","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.clim.2009.07.014","volume":"133","author":"CH Nielsen","year":"2009","unstructured":"Nielsen CH, Brix TH, Leslie RG, Heged\u00fcs L (2009) A role for autoantibodies in enhancement of pro-inflammatory cytokine responses to a self-antigen, thyroid peroxidase. Clin Immunol 133:218\u2013227","journal-title":"Clin Immunol"},{"key":"26_CR25","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1365-2265.2005.02324.x","volume":"63","author":"G Karanikas","year":"2005","unstructured":"Karanikas G, Schuetz M, Wahl K et al (2005) Relation of anti-TPO autoantibody titre and T-lymphocyte cytokine production patterns in Hashimoto\u2019s thyroiditis. Clin Endocrinol (Oxf) 63:191\u2013196","journal-title":"Clin Endocrinol (Oxf)"},{"key":"26_CR26","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/j.1365-2249.2008.03756.x","volume":"154","author":"LD Xie","year":"2008","unstructured":"Xie LD, Gao Y, Li MR, Lu GZ, Guo XH (2008) Distribution of immunoglobulin G subclasses of anti-thyroid peroxidase antibody in sera from patients with Hashimoto\u2019s thyroiditis with different thyroid functional status. Clin Exp Immunol 154:172\u2013176","journal-title":"Clin Exp Immunol"},{"key":"26_CR27","first-page":"925","volume":"82","author":"J Guo","year":"1997","unstructured":"Guo J, Jaume JC, Rapoport B, McLachlan SM (1997) Recombinant thyroid peroxidase-specific Fab converted to immunoglobulin G (IgG) molecules: evidence for thyroid cell damage by IgG1, but not IgG4, autoantibodies. J Clin Endocrinol Metab 82:925\u2013931","journal-title":"J Clin Endocrinol Metab"},{"key":"26_CR28","first-page":"372","volume":"75","author":"N Tandon","year":"1992","unstructured":"Tandon N, Morgan BP, Weetman AP (1992) Expression and function of membrane attack complex inhibitory proteins on thyroid follicular cells. Immunology 75:372\u2013377","journal-title":"Immunology"},{"key":"26_CR29","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1210\/mend.14.3.0433","volume":"14","author":"ES Park","year":"2000","unstructured":"Park ES, Kim H, Suh JM et al (2000) Thyrotropin induces SOCS-1 (suppressor of cytokine signaling-1) and SOCS-3 in FRTL-5 thyroid cells. Mol Endocrinol 14:440\u2013448","journal-title":"Mol Endocrinol"},{"key":"26_CR30","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1365-2265.1995.tb01894.x","volume":"43","author":"MP Vanderpump","year":"2005","unstructured":"Vanderpump MP, Tunbridge WM, French JM et al (2005) The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham Survey. Clin Endocrinol (Oxf) 43:55\u201368","journal-title":"Clin Endocrinol (Oxf)"},{"key":"26_CR31","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1007\/BF03346433","volume":"31","author":"E Mazza","year":"2008","unstructured":"Mazza E, Carlini M, Flecchia D et al (2008) Long-term follow-up of patients with hyperthyroidism due to Graves\u2019 disease treated with methimazole. Comparison of usual treatment schedule with drug discontinuation vs continuous treatment with low methimazole doses: a retrospective study. J Endocrinol Invest 31:866\u2013872","journal-title":"J Endocrinol Invest"},{"key":"26_CR32","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1530\/EJE-07-0450","volume":"158","author":"P Laurberg","year":"2008","unstructured":"Laurberg P, Wallin G, Tallstedt L, Abraham-Nordling M, Lundell G, T\u00f8rring O (2008) TSH receptor autoimmunity in Graves\u2019 disease after therapy with anti-thyroid drugs, surgery, or radioiodine: a 5-year prospective randomized study. Eur J Endocrinol 158:69\u201375","journal-title":"Eur J Endocrinol"}],"container-title":["Journal of Endocrinological Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s40618-013-0026-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s40618-013-0026-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s40618-013-0026-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,5]],"date-time":"2019-08-05T19:06:32Z","timestamp":1565031992000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s40618-013-0026-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["26"],"URL":"https:\/\/doi.org\/10.1007\/s40618-013-0026-9","relation":{},"ISSN":["1720-8386"],"issn-type":[{"value":"1720-8386","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1]]}}}