{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T17:24:37Z","timestamp":1793381077928,"version":"4.5.0"},"reference-count":153,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T00:00:00Z","timestamp":1695859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T00:00:00Z","timestamp":1695859200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100003500","name":"Universit\u00e0 degli Studi di Padova","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003500","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Endocrinol Invest"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>Human papillomavirus (HPV) infection is the most common sexually transmitted disease, in males and females worldwide. While the role of HPV in female diseases is well known and largely studied, males have negligibly been included in these programs, also because the proportion of women suffering and dying from HPV-related diseases is much larger than men. The aim of this review is to focus on HPV-related diseases in male patients.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We performed a literature analysis on the electronic database PubMed. We considered randomized trials, observational and retrospective studies, original articles having as topic the relationship between HPV male infection and the following items: oral, anal penile cancers, warts, condylomas, male infertility, altered sperm parameters, anti-sperm antibodies (ASA). We also included experimental in vitro studies focused on the effects of HPV infection on oocyte fertilization, blastocyst development, and trophoblastic cell invasiveness. In addition, studies describing the adjuvant administration of the HPV vaccination as a possible strategy to promote HPV clearance from semen in infected males were included.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Regarding head and neck HPV-related diseases, the most important non-neoplastic disease is recurrent respiratory papillomatosis (RRP). Regarding neoplastic diseases, the proportion of head and neck cancers attributable to HPV has increased dramatically worldwide. In addition, nowadays, it is thought that half of head and neck squamous cell carcinomas (HNSCCs) cases in the United States are caused by infection with high-risk HPV. HPV is noteworthy in andrological practice too. It was described as having a high HPV prevalence, ranging between 50 and 70%, in male penile shaft, glans penis\/coronal sulcus, semen as well as in scrotal, perianal, and anal regions. Moreover, in male patients, HPV infection has been associated, among other diseases, with penile cancers. HPV semen infection has been reported in about 10% in men from the general population and about 16% in men with unexplained infertility, although these data seem widely underestimated according to clinical experience. In particular, HPV semen infection seems to be most related to asthenozoospermia and to anti-sperm antibodies (ASAs).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>HPV infection represents a health problem with a detrimental social and public impact. Despite this evidence, little has been done to date to widely promote vaccination among young males.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s40618-023-02192-3","type":"journal-article","created":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T16:02:23Z","timestamp":1695916943000},"page":"261-274","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":65,"title":["HPV-related diseases in male patients: an underestimated conundrum"],"prefix":"10.1007","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4736-9051","authenticated-orcid":false,"given":"A.","family":"Garolla","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Graziani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Grande","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Ortolani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Ferlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,9,28]]},"reference":[{"key":"2192_CR1","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1111\/andr.284","volume":"3","author":"C Foresta","year":"2015","unstructured":"Foresta C, Noventa M, De Toni L et al (2015) HPV-DNA sperm infection and infertility: from a systematic literature review to a possible clinical management proposal. Andrology 3:163\u2013173. https:\/\/doi.org\/10.1111\/andr.284","journal-title":"Andrology"},{"issue":"Suppl 6","key":"2192_CR2","doi-asserted-by":"publisher","first-page":"G1","DOI":"10.1016\/j.vaccine.2013.10.002","volume":"31","author":"FX Bosch","year":"2013","unstructured":"Bosch FX, Broker TR, Forman D et al (2013) Comprehensive control of human papillomavirus infections and related diseases. Vaccine 31(Suppl 6):G1-31. https:\/\/doi.org\/10.1016\/j.vaccine.2013.10.002","journal-title":"Vaccine"},{"key":"2192_CR3","doi-asserted-by":"publisher","first-page":"864","DOI":"10.20892\/j.issn.2095-3941.2020.0370","volume":"17","author":"K Anna Szymonowicz","year":"2020","unstructured":"Anna Szymonowicz K, Chen J (2020) Biological and clinical aspects of HPV-related cancers. Cancer Biol Med 17:864\u2013878. https:\/\/doi.org\/10.20892\/j.issn.2095-3941.2020.0370","journal-title":"Cancer Biol Med"},{"key":"2192_CR4","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1080\/21645515.2018.1512453","volume":"15","author":"J Hirth","year":"2019","unstructured":"Hirth J (2019) Disparities in HPV vaccination rates and HPV prevalence in the United States: a review of the literature. Hum Vaccin Immunother 15:146\u2013155. https:\/\/doi.org\/10.1080\/21645515.2018.1512453","journal-title":"Hum Vaccin Immunother"},{"key":"2192_CR5","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1016\/j.idc.2013.09.001","volume":"27","author":"EF Dunne","year":"2013","unstructured":"Dunne EF, Park IU (2013) HPV and HPV-associated diseases. Infect Dis Clin North Am 27:765\u2013778. https:\/\/doi.org\/10.1016\/j.idc.2013.09.001","journal-title":"Infect Dis Clin North Am"},{"key":"2192_CR6","doi-asserted-by":"publisher","first-page":"186","DOI":"10.3892\/etm.2020.9316","volume":"20","author":"A Petca","year":"2020","unstructured":"Petca A, Borislavschi A, Zvanca ME et al (2020) Non-sexual HPV transmission and role of vaccination for a better future (Review). Exp Ther Med 20:186. https:\/\/doi.org\/10.3892\/etm.2020.9316","journal-title":"Exp Ther Med"},{"key":"2192_CR7","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1186\/1471-2458-13-117","volume":"13","author":"A Lenzi","year":"2013","unstructured":"Lenzi A, Mirone V, Gentile V et al (2013) Rome consensus conference - statement; human papilloma virus diseases in males. BMC Public Health 13:117. https:\/\/doi.org\/10.1186\/1471-2458-13-117","journal-title":"BMC Public Health"},{"key":"2192_CR8","doi-asserted-by":"publisher","first-page":"101763","DOI":"10.1016\/j.pdpdt.2020.101763","volume":"31","author":"Q Che","year":"2020","unstructured":"Che Q, Li J, Jiang L et al (2020) ALA-PDT combined with cystoscopy: a method to eliminate refractory HPV infection in a patient with condyloma acuminata. Photodiagnosis Photodyn Ther 31:101763. https:\/\/doi.org\/10.1016\/j.pdpdt.2020.101763","journal-title":"Photodiagnosis Photodyn Ther"},{"key":"2192_CR9","first-page":"1281","volume":"25","author":"I Ntanasis-Stathopoulos","year":"2020","unstructured":"Ntanasis-Stathopoulos I, Kyriazoglou A, Liontos M et al (2020) Current trends in the management and prevention of human papillomavirus (HPV) infection. J BUON 25:1281\u20131285","journal-title":"J BUON"},{"key":"2192_CR10","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00355","author":"A Garolla","year":"2019","unstructured":"Garolla A, Vitagliano A, Muscianisi F et al (2019) Role of viral infections in testicular cancer etiology: evidence from a systematic review and meta-analysis. Front Endocrinol (Lausanne). https:\/\/doi.org\/10.3389\/fendo.2019.00355","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2192_CR11","doi-asserted-by":"publisher","first-page":"1993","DOI":"10.1093\/cid\/ciac285","volume":"75","author":"HK Larsen","year":"2022","unstructured":"Larsen HK, Kjaer SK, Haedersdal M et al (2022) Anal human papillomavirus infection in kidney transplant recipients compared with immunocompetent controls. Clin Infect Dis 75:1993\u20131999. https:\/\/doi.org\/10.1093\/cid\/ciac285","journal-title":"Clin Infect Dis"},{"key":"2192_CR12","doi-asserted-by":"publisher","first-page":"591837","DOI":"10.3389\/fendo.2020.591837","volume":"11","author":"A Garolla","year":"2020","unstructured":"Garolla A, Pizzol D, Carosso AR et al (2020) Practical clinical and diagnostic pathway for the investigation of the infertile couple. Front Endocrinol (Lausanne) 11:591837. https:\/\/doi.org\/10.3389\/fendo.2020.591837","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2192_CR13","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/978-3-319-43580-0_1","volume":"206","author":"S Syrj\u00e4nen","year":"2017","unstructured":"Syrj\u00e4nen S, Rautava J, Syrj\u00e4nen K (2017) HPV in head and neck cancer-30\u00a0years of history. Recent Results Cancer Res 206:3\u201325. https:\/\/doi.org\/10.1007\/978-3-319-43580-0_1","journal-title":"Recent Results Cancer Res"},{"key":"2192_CR14","doi-asserted-by":"publisher","DOI":"10.3390\/v11100922","author":"E Tumban","year":"2019","unstructured":"Tumban E (2019) A current update on human papillomavirus-associated head and neck cancers. Viruses. https:\/\/doi.org\/10.3390\/v11100922","journal-title":"Viruses"},{"key":"2192_CR15","doi-asserted-by":"publisher","first-page":"39","DOI":"10.2147\/PHMT.S200186","volume":"11","author":"RY Seedat","year":"2020","unstructured":"Seedat RY (2020) Juvenile-onset recurrent respiratory papillomatosis diagnosis and management - a developing country review. Pediatric Health Med Ther 11:39\u201346. https:\/\/doi.org\/10.2147\/PHMT.S200186","journal-title":"Pediatric Health Med Ther"},{"key":"2192_CR16","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1007\/s00405-021-07040-9","volume":"279","author":"M Bertinazzi","year":"2022","unstructured":"Bertinazzi M, Gheit T, Polesel J et al (2022) Clinical implications of alpha, beta, and gamma HPV infection in juvenile onset recurrent respiratory papillomatosis. Eur Arch Otorhinolaryngol 279:285\u2013292. https:\/\/doi.org\/10.1007\/s00405-021-07040-9","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"2192_CR17","doi-asserted-by":"publisher","first-page":"4337","DOI":"10.3892\/etm.2019.7516","volume":"17","author":"IN Mammas","year":"2019","unstructured":"Mammas IN, Dalianis T, Doukas SG et al (2019) Paediatric virology and human papillomaviruses: an update. Exp Ther Med 17:4337\u20134343. https:\/\/doi.org\/10.3892\/etm.2019.7516","journal-title":"Exp Ther Med"},{"key":"2192_CR18","first-page":"375","volume":"34","author":"M Fusconi","year":"2014","unstructured":"Fusconi M, Grasso M, Greco A et al (2014) Recurrent respiratory papillomatosis by HPV: review of the literature and update on the use of cidofovir. Acta Otorhinolaryngol Ital 34:375\u2013381","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"2192_CR19","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/j.rmed.2017.03.030","volume":"126","author":"HR Fortes","year":"2017","unstructured":"Fortes HR, von Ranke FM, Escuissato DL et al (2017) Recurrent respiratory papillomatosis: a state-of-the-art review. Respir Med 126:116\u2013121. https:\/\/doi.org\/10.1016\/j.rmed.2017.03.030","journal-title":"Respir Med"},{"key":"2192_CR20","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1038\/s41416-019-0602-7","volume":"122","author":"ME Sabatini","year":"2020","unstructured":"Sabatini ME, Chiocca S (2020) Human papillomavirus as a driver of head and neck cancers. Br J Cancer 122:306\u2013314. https:\/\/doi.org\/10.1038\/s41416-019-0602-7","journal-title":"Br J Cancer"},{"key":"2192_CR21","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1038\/nrc.2018.11","volume":"18","author":"CR Leemans","year":"2018","unstructured":"Leemans CR, Snijders PJF, Brakenhoff RH (2018) The molecular landscape of head and neck cancer. Nat Rev Cancer 18:269\u2013282. https:\/\/doi.org\/10.1038\/nrc.2018.11","journal-title":"Nat Rev Cancer"},{"key":"2192_CR22","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1186\/1758-3284-1-36","volume":"1","author":"PKC Goon","year":"2009","unstructured":"Goon PKC, Stanley MA, Ebmeyer J et al (2009) HPV & head and neck cancer: a descriptive update. Head Neck Oncol 1:36. https:\/\/doi.org\/10.1186\/1758-3284-1-36","journal-title":"Head Neck Oncol"},{"key":"2192_CR23","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1158\/1055-9965.EPI-04-0551","volume":"14","author":"AR Kreimer","year":"2005","unstructured":"Kreimer AR, Clifford GM, Boyle P, Franceschi S (2005) Human papillomavirus types in head and neck squamous cell carcinomas worldwide: a systematic review. Cancer Epidemiol Biomarkers Prev 14:467\u2013475. https:\/\/doi.org\/10.1158\/1055-9965.EPI-04-0551","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"2192_CR24","doi-asserted-by":"publisher","first-page":"1681","DOI":"10.1093\/annonc\/mdn372","volume":"19","author":"N Termine","year":"2008","unstructured":"Termine N, Panzarella V, Falaschini S et al (2008) HPV in oral squamous cell carcinoma vs head and neck squamous cell carcinoma biopsies: a meta-analysis (1988\u20132007). Ann Oncol 19:1681\u20131690. https:\/\/doi.org\/10.1093\/annonc\/mdn372","journal-title":"Ann Oncol"},{"key":"2192_CR25","doi-asserted-by":"publisher","first-page":"20180047","DOI":"10.1259\/bjr.20180047","volume":"92","author":"E-L G\u00f6ttgens","year":"2019","unstructured":"G\u00f6ttgens E-L, Ostheimer C, Span PN et al (2019) HPV, hypoxia and radiation response in head and neck cancer. Br J Radiol 92:20180047. https:\/\/doi.org\/10.1259\/bjr.20180047","journal-title":"Br J Radiol"},{"key":"2192_CR26","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/j.immuni.2019.11.014","volume":"52","author":"AR Cillo","year":"2020","unstructured":"Cillo AR, K\u00fcrten CHL, Tabib T et al (2020) Immune landscape of viral- and carcinogen-driven head and neck cancer. Immunity 52:183-199.e9. https:\/\/doi.org\/10.1016\/j.immuni.2019.11.014","journal-title":"Immunity"},{"key":"2192_CR27","doi-asserted-by":"publisher","first-page":"528957","DOI":"10.3389\/fonc.2020.528957","volume":"10","author":"X Sastre-Garau","year":"2020","unstructured":"Sastre-Garau X, Harl\u00e9 A (2020) Pathology of HPV-associated head and neck carcinomas: recent data and perspectives for the development of specific tumor markers. Front Oncol 10:528957. https:\/\/doi.org\/10.3389\/fonc.2020.528957","journal-title":"Front Oncol"},{"key":"2192_CR28","doi-asserted-by":"publisher","first-page":"e0157976","DOI":"10.1371\/journal.pone.0157976","volume":"11","author":"EM King","year":"2016","unstructured":"King EM, Oomeer S, Gilson R et al (2016) Oral human papillomavirus infection in men who have sex with men: a systematic review and meta-analysis. PLoS ONE 11:e0157976. https:\/\/doi.org\/10.1371\/journal.pone.0157976","journal-title":"PLoS ONE"},{"key":"2192_CR29","doi-asserted-by":"publisher","first-page":"1754","DOI":"10.3892\/ijo.2013.2105","volume":"43","author":"B Ruttkay-Nedecky","year":"2013","unstructured":"Ruttkay-Nedecky B, Jimenez Jimenez AM, Nejdl L et al (2013) Relevance of infection with human papillomavirus: the role of the p53 tumor suppressor protein and E6\/E7 zinc finger proteins (Review). Int J Oncol 43:1754\u20131762. https:\/\/doi.org\/10.3892\/ijo.2013.2105","journal-title":"Int J Oncol"},{"key":"2192_CR30","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1002\/ijc.30716","volume":"141","author":"C de Martel","year":"2017","unstructured":"de Martel C, Plummer M, Vignat J, Franceschi S (2017) Worldwide burden of cancer attributable to HPV by site, country and HPV type. Int J Cancer 141:664\u2013670. https:\/\/doi.org\/10.1002\/ijc.30716","journal-title":"Int J Cancer"},{"key":"2192_CR31","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1002\/jso.26687","volume":"124","author":"BR Roman","year":"2021","unstructured":"Roman BR, Aragones A (2021) Epidemiology and incidence of HPV-related cancers of the head and neck. J Surg Oncol 124:920\u2013922. https:\/\/doi.org\/10.1002\/jso.26687","journal-title":"J Surg Oncol"},{"key":"2192_CR32","doi-asserted-by":"publisher","first-page":"S48","DOI":"10.1055\/s-0043-121596","volume":"97","author":"C Wittekindt","year":"2018","unstructured":"Wittekindt C, Wagner S, Sharma SJ et al (2018) HPV - a different view on head and neck cancer. Laryngorhinootologie 97:S48\u2013S113. https:\/\/doi.org\/10.1055\/s-0043-121596","journal-title":"Laryngorhinootologie"},{"key":"2192_CR33","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.01751","author":"JG Augustin","year":"2020","unstructured":"Augustin JG, Lepine C, Morini A et al (2020) HPV detection in head and neck squamous cell carcinomas: what is the issue? Front Oncol. https:\/\/doi.org\/10.3389\/fonc.2020.01751","journal-title":"Front Oncol"},{"key":"2192_CR34","unstructured":"Center for Disease Control and Prevention. How many cancers are linked with HPV each year?. https:\/\/www.cdc.gov\/cancer\/hpv\/statistics\/cases.htm. Accessed 1 June 2023"},{"key":"2192_CR35","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1001\/jama.2012.101","volume":"307","author":"ML Gillison","year":"2012","unstructured":"Gillison ML, Broutian T, Pickard RKL et al (2012) Prevalence of oral HPV infection in the United States, 2009\u20132010. JAMA 307:693\u2013703. https:\/\/doi.org\/10.1001\/jama.2012.101","journal-title":"JAMA"},{"key":"2192_CR36","doi-asserted-by":"publisher","first-page":"3388","DOI":"10.3390\/ijms21093388","volume":"21","author":"P Economopoulou","year":"2020","unstructured":"Economopoulou P, Kotsantis I, Psyrri A (2020) Special issue about head and neck cancers: HPV positive cancers. Int J Mol Sci 21:3388. https:\/\/doi.org\/10.3390\/ijms21093388","journal-title":"Int J Mol Sci"},{"key":"2192_CR37","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.pathol.2019.10.008","volume":"52","author":"EC Paver","year":"2020","unstructured":"Paver EC, Currie AM, Gupta R, Dahlstrom JE (2020) Human papilloma virus related squamous cell carcinomas of the head and neck: diagnosis, clinical implications and detection of HPV. Pathology 52:179\u2013191. https:\/\/doi.org\/10.1016\/j.pathol.2019.10.008","journal-title":"Pathology"},{"key":"2192_CR38","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1007\/s11912-019-0799-x","volume":"21","author":"DK Zanoni","year":"2019","unstructured":"Zanoni DK, Patel SG, Shah JP (2019) Changes in the 8th edition of the American Joint Committee on Cancer (AJCC) staging of head and neck cancer: rationale and implications. Curr Oncol Rep 21:52. https:\/\/doi.org\/10.1007\/s11912-019-0799-x","journal-title":"Curr Oncol Rep"},{"key":"2192_CR39","doi-asserted-by":"publisher","first-page":"1601","DOI":"10.21037\/atm-20-2984","volume":"8","author":"MP Strohl","year":"2020","unstructured":"Strohl MP, Wai KC, Ha PK (2020) De-intensification strategies in HPV-related oropharyngeal squamous cell carcinoma-a narrative review. Ann Transl Med 8:1601. https:\/\/doi.org\/10.21037\/atm-20-2984","journal-title":"Ann Transl Med"},{"key":"2192_CR40","doi-asserted-by":"publisher","first-page":"200245","DOI":"10.1016\/j.tvr.2022.200245","volume":"14","author":"L Galati","year":"2022","unstructured":"Galati L, Chiocca S, Duca D et al (2022) HPV and head and neck cancers: Towards early diagnosis and prevention. Tumour Virus Res 14:200245. https:\/\/doi.org\/10.1016\/j.tvr.2022.200245","journal-title":"Tumour Virus Res"},{"key":"2192_CR41","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1007\/s12094-020-02533-1","volume":"23","author":"R Mesia","year":"2021","unstructured":"Mesia R, Iglesias L, Lambea J et al (2021) SEOM clinical guidelines for the treatment of head and neck cancer (2020). Clin Transl Oncol 23:913\u2013921. https:\/\/doi.org\/10.1007\/s12094-020-02533-1","journal-title":"Clin Transl Oncol"},{"key":"2192_CR42","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10040738","author":"G Cristalli","year":"2021","unstructured":"Cristalli G, Venuti A, Giudici F et al (2021) HPV infection in middle ear squamous cell carcinoma: prevalence, genotyping and prognostic impact. J Clin Med. https:\/\/doi.org\/10.3390\/jcm10040738","journal-title":"J Clin Med"},{"key":"2192_CR43","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1038\/s41572-020-00224-3","volume":"6","author":"DE Johnson","year":"2020","unstructured":"Johnson DE, Burtness B, Leemans CR et al (2020) Head and neck squamous cell carcinoma. Nat Rev Dis Primers 6:92. https:\/\/doi.org\/10.1038\/s41572-020-00224-3","journal-title":"Nat Rev Dis Primers"},{"key":"2192_CR44","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2020.537650","author":"N Aggarwal","year":"2020","unstructured":"Aggarwal N, Yadav J, Thakur K et al (2020) Human papillomavirus infection in head and neck squamous cell carcinomas: transcriptional triggers and changed disease patterns. Front Cell Infect Microbiol. https:\/\/doi.org\/10.3389\/fcimb.2020.537650","journal-title":"Front Cell Infect Microbiol"},{"key":"2192_CR45","doi-asserted-by":"publisher","first-page":"45","DOI":"10.3390\/cancers13010045","volume":"13","author":"KJW Chang Sing Pang","year":"2020","unstructured":"Chang Sing Pang KJW, Mur T, Collins L et al (2020) Human papillomavirus in sinonasal squamous cell carcinoma: a systematic review and meta-analysis. Cancers (Basel) 13:45. https:\/\/doi.org\/10.3390\/cancers13010045","journal-title":"Cancers (Basel)"},{"key":"2192_CR46","doi-asserted-by":"publisher","first-page":"117383","DOI":"10.1016\/j.lfs.2020.117383","volume":"245","author":"K Devaraja","year":"2020","unstructured":"Devaraja K, Aggarwal S, Verma SS, Gupta SC (2020) Clinico-pathological peculiarities of human papilloma virus driven head and neck squamous cell carcinoma: a comprehensive update. Life Sci 245:117383. https:\/\/doi.org\/10.1016\/j.lfs.2020.117383","journal-title":"Life Sci"},{"key":"2192_CR47","doi-asserted-by":"publisher","first-page":"2407","DOI":"10.1007\/s00405-020-05979-9","volume":"277","author":"P Machczy\u0144ski","year":"2020","unstructured":"Machczy\u0144ski P, Majchrzak E, Niewinski P et al (2020) A review of the 8th edition the of the AJCC staging system for oropharyngeal cancer according to HPV status. Eur Arch Oto-Rhino-Laryngol 277:2407\u20132412. https:\/\/doi.org\/10.1007\/s00405-020-05979-9","journal-title":"Eur Arch Oto-Rhino-Laryngol"},{"key":"2192_CR48","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1002\/lio2.545","volume":"6","author":"JJ Benedict","year":"2021","unstructured":"Benedict JJ, Derkay CS (2021) Recurrent respiratory papillomatosis: a 2020 perspective. Laryngoscope Investig Otolaryngol 6:340\u2013345. https:\/\/doi.org\/10.1002\/lio2.545","journal-title":"Laryngoscope Investig Otolaryngol"},{"key":"2192_CR49","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1111\/joim.13010","volume":"287","author":"A N\u00e4sman","year":"2020","unstructured":"N\u00e4sman A, Du J, Dalianis T (2020) A global epidemic increase of an HPV-induced tonsil and tongue base cancer \u2013 potential benefit from a pan-gender use of HPV vaccine. J Intern Med 287:134\u2013152. https:\/\/doi.org\/10.1111\/joim.13010","journal-title":"J Intern Med"},{"key":"2192_CR50","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1136\/jclinpath-2020-206686","volume":"73","author":"S Rahimi","year":"2020","unstructured":"Rahimi S (2020) HPV-related squamous cell carcinoma of oropharynx: a review. J Clin Pathol 73:624\u2013629. https:\/\/doi.org\/10.1136\/jclinpath-2020-206686","journal-title":"J Clin Pathol"},{"key":"2192_CR51","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2021.677900","author":"S Brennan","year":"2021","unstructured":"Brennan S, Baird A-M, O\u2019Regan E, Sheils O (2021) The role of human papilloma virus in dictating outcomes in head and neck squamous cell carcinoma. Front Mol Biosci. https:\/\/doi.org\/10.3389\/fmolb.2021.677900","journal-title":"Front Mol Biosci"},{"key":"2192_CR52","doi-asserted-by":"publisher","first-page":"1284","DOI":"10.1007\/s12250-021-00413-8","volume":"36","author":"H Dong","year":"2021","unstructured":"Dong H, Shu X, Xu Q et al (2021) Current status of human papillomavirus-related head and neck cancer: from viral genome to patient care. Virol Sin 36:1284\u20131302. https:\/\/doi.org\/10.1007\/s12250-021-00413-8","journal-title":"Virol Sin"},{"key":"2192_CR53","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.3390\/biology10121232","volume":"10","author":"R Blanco","year":"2021","unstructured":"Blanco R, Carrillo-Beltr\u00e1n D, Corval\u00e1n AH, Aguayo F (2021) High-Risk human papillomavirus and Epstein-Barr virus coinfection: a potential role in head and neck carcinogenesis. Biology (Basel) 10:1232. https:\/\/doi.org\/10.3390\/biology10121232","journal-title":"Biology (Basel)"},{"key":"2192_CR54","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.2178","author":"R Gupta","year":"2021","unstructured":"Gupta R, Rady PL, Sikora AG, Tyring SK (2021) The role of human papillomavirus in the pathogenesis of sinonasal inverted papilloma: a narrative review. Rev Med Virol. https:\/\/doi.org\/10.1002\/rmv.2178","journal-title":"Rev Med Virol"},{"key":"2192_CR55","doi-asserted-by":"publisher","first-page":"2234","DOI":"10.3390\/v13112234","volume":"13","author":"E Pe\u0161ut","year":"2021","unstructured":"Pe\u0161ut E, \u0110uki\u0107 A, Luli\u0107 L et al (2021) Human papillomaviruses-associated cancers: an update of current knowledge. Viruses 13:2234. https:\/\/doi.org\/10.3390\/v13112234","journal-title":"Viruses"},{"key":"2192_CR56","doi-asserted-by":"publisher","first-page":"1624","DOI":"10.3390\/v13081624","volume":"13","author":"S Syrj\u00e4nen","year":"2021","unstructured":"Syrj\u00e4nen S, Syrj\u00e4nen K (2021) HPV-associated benign squamous cell papillomas in the upper aero-digestive tract and their malignant potential. Viruses 13:1624. https:\/\/doi.org\/10.3390\/v13081624","journal-title":"Viruses"},{"key":"2192_CR57","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.625330","author":"S Gougousis","year":"2021","unstructured":"Gougousis S, Mouchtaropoulou E, Besli I et al (2021) HPV-related oropharyngeal cancer and biomarkers based on epigenetics and microbiome profile. Front Cell Dev Biol. https:\/\/doi.org\/10.3389\/fcell.2020.625330","journal-title":"Front Cell Dev Biol"},{"key":"2192_CR58","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.3390\/v13061173","volume":"13","author":"M Hoffmann","year":"2021","unstructured":"Hoffmann M, Quabius ES (2021) Relevance of human papillomaviruses in head and neck cancer\u2014what remains in 2021 from a clinician\u2019s point of view? Viruses 13:1173. https:\/\/doi.org\/10.3390\/v13061173","journal-title":"Viruses"},{"key":"2192_CR59","doi-asserted-by":"publisher","first-page":"1402","DOI":"10.3390\/ijms22031402","volume":"22","author":"G Riva","year":"2021","unstructured":"Riva G, Albano C, Gugliesi F et al (2021) HPV meets APOBEC: new players in head and neck cancer. Int J Mol Sci 22:1402. https:\/\/doi.org\/10.3390\/ijms22031402","journal-title":"Int J Mol Sci"},{"key":"2192_CR60","doi-asserted-by":"publisher","first-page":"832","DOI":"10.3122\/jabfm.2021.04.200588","volume":"34","author":"JC Nogues","year":"2021","unstructured":"Nogues JC, Fassas S, Mulcahy C, Zapanta PE (2021) Human papillomavirus-associated head and neck cancer. J Am Board Family Med 34:832\u2013837. https:\/\/doi.org\/10.3122\/jabfm.2021.04.200588","journal-title":"J Am Board Family Med"},{"key":"2192_CR61","doi-asserted-by":"publisher","first-page":"8395","DOI":"10.3390\/ijms23158395","volume":"23","author":"GB Morand","year":"2022","unstructured":"Morand GB, Cardona I, Cruz SBSC et al (2022) Therapeutic vaccines for HPV-associated oropharyngeal and cervical cancer: the next de-intensification strategy? Int J Mol Sci 23:8395. https:\/\/doi.org\/10.3390\/ijms23158395","journal-title":"Int J Mol Sci"},{"key":"2192_CR62","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1038\/s41571-022-00603-7","volume":"19","author":"M Lechner","year":"2022","unstructured":"Lechner M, Liu J, Masterson L, Fenton TR (2022) HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management. Nat Rev Clin Oncol 19:306\u2013327. https:\/\/doi.org\/10.1038\/s41571-022-00603-7","journal-title":"Nat Rev Clin Oncol"},{"key":"2192_CR63","first-page":"245","volume":"30","author":"KL Stratton","year":"2016","unstructured":"Stratton KL, Culkin DJ (2016) A contemporary review of HPV and penile cancer. Oncology (Williston Park) 30:245\u2013249","journal-title":"Oncology (Williston Park)"},{"key":"2192_CR64","doi-asserted-by":"publisher","first-page":"646","DOI":"10.3238\/arztebl.2018.0646","volume":"115","author":"OW Hakenberg","year":"2018","unstructured":"Hakenberg OW, Dr\u00e4ger DL, Erbersdobler A et al (2018) The diagnosis and treatment of penile cancer. Dtsch Arztebl Int 115:646\u2013652. https:\/\/doi.org\/10.3238\/arztebl.2018.0646","journal-title":"Dtsch Arztebl Int"},{"key":"2192_CR65","doi-asserted-by":"publisher","first-page":"151284","DOI":"10.1016\/j.soncn.2022.151284","volume":"38","author":"L Elst","year":"2022","unstructured":"Elst L, Albersen M (2022) HPV vaccination: does it have a role in preventing penile cancer and other preneoplastic lesions? Semin Oncol Nurs 38:151284. https:\/\/doi.org\/10.1016\/j.soncn.2022.151284","journal-title":"Semin Oncol Nurs"},{"key":"2192_CR66","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1038\/s41572-021-00246-5","volume":"7","author":"A Thomas","year":"2021","unstructured":"Thomas A, Necchi A, Muneer A et al (2021) Penile cancer. Nat Rev Dis Primers 7:11. https:\/\/doi.org\/10.1038\/s41572-021-00246-5","journal-title":"Nat Rev Dis Primers"},{"key":"2192_CR67","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1128\/CMR.05028-11","volume":"25","author":"MA Stanley","year":"2012","unstructured":"Stanley MA (2012) Epithelial cell responses to infection with human papillomavirus. Clin Microbiol Rev 25:215\u2013222. https:\/\/doi.org\/10.1128\/CMR.05028-11","journal-title":"Clin Microbiol Rev"},{"key":"2192_CR68","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1053\/j.semdp.2011.09.001","volume":"29","author":"A Chaux","year":"2012","unstructured":"Chaux A, Cubilla AL (2012) The role of human papillomavirus infection in the pathogenesis of penile squamous cell carcinomas. Semin Diagn Pathol 29:67\u201371. https:\/\/doi.org\/10.1053\/j.semdp.2011.09.001","journal-title":"Semin Diagn Pathol"},{"key":"2192_CR69","first-page":"61","volume":"54","author":"P Canepa","year":"2013","unstructured":"Canepa P, Orsi A, Martini M, Icardi G (2013) HPV related diseases in males: a heavy vaccine-preventable burden. J Prev Med Hyg 54:61\u201370","journal-title":"J Prev Med Hyg"},{"key":"2192_CR70","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1007\/s00384-014-1922-y","volume":"29","author":"R Kaderli","year":"2014","unstructured":"Kaderli R, Schn\u00fcriger B, Br\u00fcgger LE (2014) The impact of smoking on HPV infection and the development of anogenital warts. Int J Colorectal Dis 29:899\u2013908. https:\/\/doi.org\/10.1007\/s00384-014-1922-y","journal-title":"Int J Colorectal Dis"},{"key":"2192_CR71","doi-asserted-by":"publisher","first-page":"e423","DOI":"10.1016\/j.lpm.2014.10.001","volume":"43","author":"S de Sanjos\u00e9","year":"2014","unstructured":"de Sanjos\u00e9 S, Bruni L, Alemany L (2014) HPV in genital cancers (at the exception of cervical cancer) and anal cancers. Presse Med 43:e423\u2013e428. https:\/\/doi.org\/10.1016\/j.lpm.2014.10.001","journal-title":"Presse Med"},{"key":"2192_CR72","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1016\/j.bpobgyn.2014.07.002","volume":"28","author":"M Steben","year":"2014","unstructured":"Steben M, Garland SM (2014) Genital warts. Best Pract Res Clin Obstet Gynaecol 28:1063\u20131073. https:\/\/doi.org\/10.1016\/j.bpobgyn.2014.07.002","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"2192_CR73","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1007\/s00105-015-3630-0","volume":"66","author":"U Wieland","year":"2015","unstructured":"Wieland U, Kreuter A (2015) HPV-induzierte anale L\u00e4sionen. Hautarzt 66:439\u2013445. https:\/\/doi.org\/10.1007\/s00105-015-3630-0","journal-title":"Hautarzt"},{"key":"2192_CR74","doi-asserted-by":"publisher","first-page":"111","DOI":"10.4103\/0019-5154.152501","volume":"60","author":"C Bunker","year":"2015","unstructured":"Bunker C, Shim T (2015) Male genital lichen sclerosus. Indian J Dermatol 60:111. https:\/\/doi.org\/10.4103\/0019-5154.152501","journal-title":"Indian J Dermatol"},{"key":"2192_CR75","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1111\/cup.12835","volume":"43","author":"PS Rush","year":"2016","unstructured":"Rush PS, Shiau JM, Hibler BP et al (2016) Primary cutaneous adenosquamous carcinoma of the penis: the first characterization of HPV status in this rare and diagnostically challenging entity with review of glandular carcinomas of the penis. J Cutan Pathol 43:1226\u20131230. https:\/\/doi.org\/10.1111\/cup.12835","journal-title":"J Cutan Pathol"},{"key":"2192_CR76","doi-asserted-by":"publisher","first-page":"92","DOI":"10.7556\/jaoa.2018.024","volume":"118","author":"DJ Witchey","year":"2018","unstructured":"Witchey DJ, Witchey NB, Roth-Kauffman MM, Kauffman MK (2018) Plantar warts: epidemiology, pathophysiology, and clinical management. J Am Osteopath Assoc 118:92. https:\/\/doi.org\/10.7556\/jaoa.2018.024","journal-title":"J Am Osteopath Assoc"},{"key":"2192_CR77","doi-asserted-by":"publisher","DOI":"10.23736\/S0393-2249.18.03141-7","author":"T Cai","year":"2018","unstructured":"Cai T, Di Vico T, Durante J et al (2018) Human papilloma virus and genitourinary cancers: a narrative review. Minerva Urol Nefrol. https:\/\/doi.org\/10.23736\/S0393-2249.18.03141-7","journal-title":"Minerva Urol Nefrol"},{"key":"2192_CR78","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jiph.2018.06.005","volume":"12","author":"J Krzowska-Firych","year":"2019","unstructured":"Krzowska-Firych J, Lucas G, Lucas C et al (2019) An overview of human papillomavirus (HPV) as an etiological factor of the anal cancer. J Infect Public Health 12:1\u20136. https:\/\/doi.org\/10.1016\/j.jiph.2018.06.005","journal-title":"J Infect Public Health"},{"key":"2192_CR79","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/j.euf.2019.06.013","volume":"5","author":"S Canete-Portillo","year":"2019","unstructured":"Canete-Portillo S, Sanchez DF, Cubilla AL (2019) Pathology of invasive and intraepithelial penile neoplasia. Eur Urol Focus 5:713\u2013717. https:\/\/doi.org\/10.1016\/j.euf.2019.06.013","journal-title":"Eur Urol Focus"},{"key":"2192_CR80","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2019.8181","author":"L Iorga","year":"2019","unstructured":"Iorga L, Marcu R, Diaconu C et al (2019) Penile carcinoma and HPV infection (Review). Exp Ther Med. https:\/\/doi.org\/10.3892\/etm.2019.8181","journal-title":"Exp Ther Med"},{"key":"2192_CR81","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1080\/13685538.2018.1455178","volume":"23","author":"GI Russo","year":"2020","unstructured":"Russo GI, Calogero AE, Condorelli RA et al (2020) Human papillomavirus and risk of prostate cancer: a systematic review and meta-analysis. Aging Male 23:132\u2013138. https:\/\/doi.org\/10.1080\/13685538.2018.1455178","journal-title":"Aging Male"},{"key":"2192_CR82","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1097\/MOU.0000000000000730","volume":"30","author":"JF da Costa Nunes","year":"2020","unstructured":"da Costa Nunes JF, Pires S, Chade DC (2020) Human papillomavirus vaccination and prevention of intraepithelial neoplasia and penile cancer. Curr Opin Urol 30:208\u2013212. https:\/\/doi.org\/10.1097\/MOU.0000000000000730","journal-title":"Curr Opin Urol"},{"key":"2192_CR83","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11255-019-02302-2","volume":"52","author":"M Sarier","year":"2020","unstructured":"Sarier M, Ceyhan AM, Sepin N et al (2020) HPV infection in urology practice. Int Urol Nephrol 52:1\u20138. https:\/\/doi.org\/10.1007\/s11255-019-02302-2","journal-title":"Int Urol Nephrol"},{"key":"2192_CR84","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1007\/s00105-020-04562-x","volume":"71","author":"U Wieland","year":"2020","unstructured":"Wieland U, Oellig F, Kreuter A (2020) Anal dysplasia and anal cancer. English version. Hautarzt 71:74\u201381. https:\/\/doi.org\/10.1007\/s00105-020-04562-x","journal-title":"Hautarzt"},{"key":"2192_CR85","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.2219","author":"M Farahmand","year":"2021","unstructured":"Farahmand M, Monavari SH, Tavakoli A (2021) Prevalence and genotype distribution of human papillomavirus infection in different anatomical sites among men who have sex with men: a systematic review and meta-analysis. Rev Med Virol. https:\/\/doi.org\/10.1002\/rmv.2219","journal-title":"Rev Med Virol"},{"key":"2192_CR86","doi-asserted-by":"publisher","first-page":"1939","DOI":"10.1097\/QAD.0000000000002975","volume":"35","author":"A Albuquerque","year":"2021","unstructured":"Albuquerque A, Cappello C, Stirrup O (2021) High-risk human papilloma virus, precancerous lesions and cancer in anal condylomas. AIDS 35:1939\u20131948. https:\/\/doi.org\/10.1097\/QAD.0000000000002975","journal-title":"AIDS"},{"key":"2192_CR87","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.1007\/s00345-020-03510-7","volume":"39","author":"J Vanthoor","year":"2021","unstructured":"Vanthoor J, Vos G, Albersen M (2021) Penile cancer: potential target for immunotherapy? World J Urol 39:1405\u20131411. https:\/\/doi.org\/10.1007\/s00345-020-03510-7","journal-title":"World J Urol"},{"key":"2192_CR88","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1016\/j.eururo.2022.06.016","volume":"82","author":"H Moch","year":"2022","unstructured":"Moch H, Amin MB, Berney DM et al (2022) The 2022 World Health Organization classification of tumours of the urinary system and male genital organs\u2014part A: renal, penile, and testicular tumours. Eur Urol 82:458\u2013468. https:\/\/doi.org\/10.1016\/j.eururo.2022.06.016","journal-title":"Eur Urol"},{"key":"2192_CR89","doi-asserted-by":"publisher","DOI":"10.47176\/mjiri.35.65","author":"M Soheili","year":"2021","unstructured":"Soheili M, Keyvani H, Soheili M, Nasseri S (2021) Human papilloma virus: a review study of epidemiology, carcinogenesis, diagnostic methods, and treatment of all HPV-related cancers. Med J Islam Repub Iran. https:\/\/doi.org\/10.47176\/mjiri.35.65","journal-title":"Med J Islam Repub Iran"},{"key":"2192_CR90","doi-asserted-by":"publisher","first-page":"8500","DOI":"10.3390\/ijerph18168500","volume":"18","author":"F Crocetto","year":"2021","unstructured":"Crocetto F, Arcaniolo D, Napolitano L et al (2021) Impact of sexual activity on the risk of male genital tumors: a systematic review of the literature. Int J Environ Res Public Health 18:8500. https:\/\/doi.org\/10.3390\/ijerph18168500","journal-title":"Int J Environ Res Public Health"},{"key":"2192_CR91","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2021.2016007","author":"E Meites","year":"2022","unstructured":"Meites E, Wilkin TJ, Markowitz LE (2022) Review of human papillomavirus (HPV) burden and HPV vaccination for gay, bisexual, and other men who have sex with men and transgender women in the United States. Hum Vaccin Immunother. https:\/\/doi.org\/10.1080\/21645515.2021.2016007","journal-title":"Hum Vaccin Immunother"},{"key":"2192_CR92","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.28208","author":"J Sun","year":"2023","unstructured":"Sun J, Xu J, Liu C et al (2023) The association between human papillomavirus and bladder cancer: evidence from meta-analysis and two-sample mendelian randomization. J Med Virol. https:\/\/doi.org\/10.1002\/jmv.28208","journal-title":"J Med Virol"},{"key":"2192_CR93","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21010222","author":"G Curty","year":"2019","unstructured":"Curty G, de Carvalho PS, Soares MA (2019) The Role of the cervicovaginal microbiome on the genesis and as a biomarker of premalignant cervical intraepithelial neoplasia and invasive cervical cancer. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms21010222","journal-title":"Int J Mol Sci"},{"key":"2192_CR94","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/s1368-8375(01)00050-1","volume":"38","author":"R K\u00fcffer","year":"2002","unstructured":"K\u00fcffer R, Lombardi T (2002) Premalignant lesions of the oral mucosa. A discussion about the place of oral intraepithelial neoplasia (OIN). Oral Oncol 38:125\u2013130. https:\/\/doi.org\/10.1016\/s1368-8375(01)00050-1","journal-title":"Oral Oncol"},{"key":"2192_CR95","doi-asserted-by":"publisher","first-page":"1833","DOI":"10.1002\/ijc.33748","volume":"149","author":"RP van der Zee","year":"2021","unstructured":"van der Zee RP, Meijer CJLM, Cuming T et al (2021) Characterisation of anal intraepithelial neoplasia and anal cancer in HIV-positive men by immunohistochemical markers p16, Ki-67, HPV-E4 and DNA methylation markers. Int J Cancer 149:1833\u20131844. https:\/\/doi.org\/10.1002\/ijc.33748","journal-title":"Int J Cancer"},{"key":"2192_CR96","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/S0140-6736(20)32667-2","volume":"397","author":"A Agarwal","year":"2021","unstructured":"Agarwal A, Baskaran S, Parekh N et al (2021) Male infertility. Lancet 397:319\u2013333. https:\/\/doi.org\/10.1016\/S0140-6736(20)32667-2","journal-title":"Lancet"},{"key":"2192_CR97","doi-asserted-by":"publisher","first-page":"743","DOI":"10.3390\/vaccines8040743","volume":"8","author":"L De Toni","year":"2020","unstructured":"De Toni L, Muscianisi F, Corsini C et al (2020) Serum Anti-HPV antibody titer as a marker of vaccine effectiveness in males with genital infection. Vaccines (Basel) 8:743. https:\/\/doi.org\/10.3390\/vaccines8040743","journal-title":"Vaccines (Basel)"},{"key":"2192_CR98","doi-asserted-by":"publisher","first-page":"e177","DOI":"10.1017\/S0950268819000621","volume":"147","author":"G Capra","year":"2019","unstructured":"Capra G, Schillaci R, Bosco L et al (2019) HPV infection in semen: results from a new molecular approach. Epidemiol Infect 147:e177. https:\/\/doi.org\/10.1017\/S0950268819000621","journal-title":"Epidemiol Infect"},{"key":"2192_CR99","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1093\/humrep\/det453","volume":"29","author":"C Laprise","year":"2014","unstructured":"Laprise C, Trottier H, Monnier P et al (2014) Prevalence of human papillomaviruses in semen: a systematic review and meta-analysis. Hum Reprod 29:640\u2013651. https:\/\/doi.org\/10.1093\/humrep\/det453","journal-title":"Hum Reprod"},{"key":"2192_CR100","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1186\/s13027-021-00368-1","volume":"16","author":"M Isaguliants","year":"2021","unstructured":"Isaguliants M, Krasnyak S, Smirnova O et al (2021) Genetic instability and anti-HPV immune response as drivers of infertility associated with HPV infection. Infect Agent Cancer 16:29. https:\/\/doi.org\/10.1186\/s13027-021-00368-1","journal-title":"Infect Agent Cancer"},{"key":"2192_CR101","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1111\/andr.12948","volume":"9","author":"J Moreno-Sepulveda","year":"2021","unstructured":"Moreno-Sepulveda J, Rajmil O (2021) Seminal human papillomavirus infection and reproduction: a systematic review and meta-analysis. Andrology 9:478\u2013502. https:\/\/doi.org\/10.1111\/andr.12948","journal-title":"Andrology"},{"key":"2192_CR102","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1111\/j.1365-2605.2010.01075.x","volume":"34","author":"C Foresta","year":"2011","unstructured":"Foresta C, Ferlin A, Bertoldo A et al (2011) Human papilloma virus in the sperm cryobank: an emerging problem? Int J Androl 34:242\u2013246. https:\/\/doi.org\/10.1111\/j.1365-2605.2010.01075.x","journal-title":"Int J Androl"},{"key":"2192_CR103","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.fertnstert.2012.09.006","volume":"99","author":"A Garolla","year":"2013","unstructured":"Garolla A, Pizzol D, Bertoldo A et al (2013) Association, prevalence, and clearance of human papillomavirus and antisperm antibodies in infected semen samples from infertile patients. Fertil Steril 99:125-131.e2. https:\/\/doi.org\/10.1016\/j.fertnstert.2012.09.006","journal-title":"Fertil Steril"},{"key":"2192_CR104","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9061644","author":"A Ferlin","year":"2020","unstructured":"Ferlin A, Foresta C (2020) Infertility: practical clinical issues for routine investigation of the male partner. J Clin Med. https:\/\/doi.org\/10.3390\/jcm9061644","journal-title":"J Clin Med"},{"key":"2192_CR105","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1186\/s12879-021-06029-3","volume":"21","author":"H Tuominen","year":"2021","unstructured":"Tuominen H, Rautava J, Kero K et al (2021) HPV infection and bacterial microbiota in the semen from healthy men. BMC Infect Dis 21:373. https:\/\/doi.org\/10.1186\/s12879-021-06029-3","journal-title":"BMC Infect Dis"},{"key":"2192_CR106","doi-asserted-by":"publisher","first-page":"643539","DOI":"10.3389\/fendo.2021.643539","volume":"12","author":"F Muscianisi","year":"2021","unstructured":"Muscianisi F, De Toni L, Giorato G et al (2021) Is HPV the novel target in male idiopathic infertility? A systematic review of the literature. Front Endocrinol (Lausanne) 12:643539. https:\/\/doi.org\/10.3389\/fendo.2021.643539","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2192_CR107","doi-asserted-by":"publisher","first-page":"700792","DOI":"10.3389\/fmed.2021.700792","volume":"8","author":"A Ciavattini","year":"2021","unstructured":"Ciavattini A, Marconi C, Giannella L et al (2021) The impact of 9-valent HPV vaccination on couple infertility prevention: a comprehensive review. Front Med (Lausanne) 8:700792. https:\/\/doi.org\/10.3389\/fmed.2021.700792","journal-title":"Front Med (Lausanne)"},{"key":"2192_CR108","doi-asserted-by":"publisher","first-page":"492","DOI":"10.5935\/1518-0557.20200020","volume":"24","author":"ACX Goulart","year":"2020","unstructured":"Goulart ACX, Farnezi HCM, Fran\u00e7a JPBM et al (2020) HIV, HPV and chlamydia trachomatis: impacts on male fertility. JBRA Assist Reprod 24:492\u2013497. https:\/\/doi.org\/10.5935\/1518-0557.20200020","journal-title":"JBRA Assist Reprod"},{"key":"2192_CR109","doi-asserted-by":"publisher","DOI":"10.3390\/medicina54040050","author":"K Zacharis","year":"2018","unstructured":"Zacharis K, Messini CI, Anifandis G et al (2018) Human papilloma virus (HPV) and fertilization: a mini review. Medicina (Kaunas). https:\/\/doi.org\/10.3390\/medicina54040050","journal-title":"Medicina (Kaunas)"},{"key":"2192_CR110","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1007\/s00404-013-2711-5","volume":"287","author":"LJ Hong","year":"2013","unstructured":"Hong LJ, Oshiro BT, Chan PJ (2013) HPV-16 exposed mouse embryos: a potential model for pregnancy wastage. Arch Gynecol Obstet 287:1093\u20131097. https:\/\/doi.org\/10.1007\/s00404-013-2711-5","journal-title":"Arch Gynecol Obstet"},{"key":"2192_CR111","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.fertnstert.2015.09.018","volume":"105","author":"A Garolla","year":"2016","unstructured":"Garolla A, Engl B, Pizzol D et al (2016) Spontaneous fertility and in vitro fertilization outcome: new evidence of human papillomavirus sperm infection. Fertil Steril 105:65-72.e1. https:\/\/doi.org\/10.1016\/j.fertnstert.2015.09.018","journal-title":"Fertil Steril"},{"key":"2192_CR112","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.rbmo.2014.12.016","volume":"30","author":"S La Vignera","year":"2015","unstructured":"La Vignera S, Vicari E, Condorelli RA et al (2015) Prevalence of human papilloma virus infection in patients with male accessory gland infection. Reprod Biomed Online 30:385\u2013391. https:\/\/doi.org\/10.1016\/j.rbmo.2014.12.016","journal-title":"Reprod Biomed Online"},{"key":"2192_CR113","doi-asserted-by":"publisher","DOI":"10.1093\/hropen\/hoab037","author":"HM Bhandari","year":"2021","unstructured":"Bhandari HM, Mitchell T, Duffy J et al (2021) ESHRE guideline: medically assisted reproduction in patients with a viral infection\/disease. Hum Reprod Open. https:\/\/doi.org\/10.1093\/hropen\/hoab037","journal-title":"Hum Reprod Open"},{"key":"2192_CR114","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1093\/humrep\/des009","volume":"27","author":"A Garolla","year":"2012","unstructured":"Garolla A, Lenzi A, Palu G et al (2012) Human papillomavirus sperm infection and assisted reproduction: a dangerous hazard with a possible safe solution. Hum Reprod 27:967\u2013973. https:\/\/doi.org\/10.1093\/humrep\/des009","journal-title":"Hum Reprod"},{"key":"2192_CR115","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1093\/biolre\/ioaa173","volume":"104","author":"L De Toni","year":"2021","unstructured":"De Toni L, Cosci I, Carosso A et al (2021) Hyaluronidase-based swim-up for semen selection in patients with human papillomavirus semen infection. Biol Reprod 104:211\u2013222. https:\/\/doi.org\/10.1093\/biolre\/ioaa173","journal-title":"Biol Reprod"},{"key":"2192_CR116","doi-asserted-by":"publisher","first-page":"6","DOI":"10.3390\/jpm13010006","volume":"13","author":"I Cosci","year":"2022","unstructured":"Cosci I, De Toni L, Vasoin De Prosperi F et al (2022) Intra uterine insemination in two couples with HPV detection by hyaluronidase-based swim-up washing: cases report. J Pers Med 13:6. https:\/\/doi.org\/10.3390\/jpm13010006","journal-title":"J Pers Med"},{"key":"2192_CR117","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1186\/s12916-018-1098-3","volume":"16","author":"T Harder","year":"2018","unstructured":"Harder T, Wichmann O, Klug SJ et al (2018) Efficacy, effectiveness and safety of vaccination against human papillomavirus in males: a systematic review. BMC Med 16:110. https:\/\/doi.org\/10.1186\/s12916-018-1098-3","journal-title":"BMC Med"},{"key":"2192_CR118","doi-asserted-by":"publisher","first-page":"70","DOI":"10.23736\/S2724-6507.22.03667-3","volume":"47","author":"F Muscianisi","year":"2022","unstructured":"Muscianisi F, Foresta C, Garolla A (2022) Role of HPV vaccination for prevention of male infertility. Minerva Endocrinol 47:70\u201376. https:\/\/doi.org\/10.23736\/S2724-6507.22.03667-3","journal-title":"Minerva Endocrinol"},{"key":"2192_CR119","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.1016\/j.ebiom.2015.09.005","volume":"2","author":"C Foresta","year":"2015","unstructured":"Foresta C, Garolla A, Parisi S et al (2015) HPV prophylactic vaccination in males improves the clearance of semen infection. EBioMedicine 2:1487\u20131493. https:\/\/doi.org\/10.1016\/j.ebiom.2015.09.005","journal-title":"EBioMedicine"},{"key":"2192_CR120","first-page":"261","volume":"97","author":"DC Baird","year":"2018","unstructured":"Baird DC, Meyers GJ, Hu JS (2018) Testicular cancer: diagnosis and treatment. Am Fam Physician 97:261\u2013268","journal-title":"Am Fam Physician"},{"key":"2192_CR121","doi-asserted-by":"publisher","first-page":"172","DOI":"10.3389\/fendo.2012.00172","volume":"3","author":"A Garolla","year":"2012","unstructured":"Garolla A, Pizzol D, Bertoldo A et al (2012) Testicular cancer and HPV semen infection. Front Endocrinol (Lausanne) 3:172. https:\/\/doi.org\/10.3389\/fendo.2012.00172","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2192_CR122","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1136\/sti.67.3.207","volume":"67","author":"J Green","year":"1991","unstructured":"Green J, Monteiro E, Bolton VN et al (1991) Detection of human papillomavirus DNA by PCR in semen from patients with and without penile warts. Sex Transm Infect 67:207\u2013210. https:\/\/doi.org\/10.1136\/sti.67.3.207","journal-title":"Sex Transm Infect"},{"key":"2192_CR123","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1016\/S0015-0282(16)56719-3","volume":"61","author":"PJ Chan","year":"1994","unstructured":"Chan PJ, Su BC, Kalugdan T et al (1994) Human papillomavirus gene sequences in washed human sperm deoxyribonucleic acid. Fertil Steril 61:982\u2013985. https:\/\/doi.org\/10.1016\/S0015-0282(16)56719-3","journal-title":"Fertil Steril"},{"key":"2192_CR124","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.1016\/S0015-0282(97)81454-9","volume":"67","author":"YM Lai","year":"1997","unstructured":"Lai YM, Lee JF, Huang HY et al (1997) The effect of human papillomavirus infection on sperm cell motility. Fertil Steril 67:1152\u20131155. https:\/\/doi.org\/10.1016\/S0015-0282(97)81454-9","journal-title":"Fertil Steril"},{"key":"2192_CR125","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1016\/S0029-7844(00)01183-2","volume":"97","author":"O Olatunbosun","year":"2001","unstructured":"Olatunbosun O (2001) Human papillomavirus DNA detection in sperm using polymerase chain reaction. Obstet Gynecol 97:357\u2013360. https:\/\/doi.org\/10.1016\/S0029-7844(00)01183-2","journal-title":"Obstet Gynecol"},{"key":"2192_CR126","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1016\/j.fertnstert.2008.10.050","volume":"93","author":"C Foresta","year":"2010","unstructured":"Foresta C, Garolla A, Zuccarello D et al (2010) Human papillomavirus found in sperm head of young adult males affects the progressive motility. Fertil Steril 93:802\u2013806. https:\/\/doi.org\/10.1016\/j.fertnstert.2008.10.050","journal-title":"Fertil Steril"},{"key":"2192_CR127","doi-asserted-by":"publisher","first-page":"1723","DOI":"10.1016\/j.fertnstert.2009.11.012","volume":"94","author":"C Foresta","year":"2010","unstructured":"Foresta C, Pizzol D, Moretti A et al (2010) Clinical and prognostic significance of human papillomavirus DNA in the sperm or exfoliated cells of infertile patients and subjects with risk factors. Fertil Steril 94:1723\u20131727. https:\/\/doi.org\/10.1016\/j.fertnstert.2009.11.012","journal-title":"Fertil Steril"},{"key":"2192_CR128","doi-asserted-by":"publisher","first-page":"1845","DOI":"10.1016\/j.fertnstert.2010.11.047","volume":"95","author":"A Perino","year":"2011","unstructured":"Perino A, Giovannelli L, Schillaci R et al (2011) Human papillomavirus infection in couples undergoing in vitro fertilization procedures: impact on reproductive outcomes. Fertil Steril 95:1845\u20131848. https:\/\/doi.org\/10.1016\/j.fertnstert.2010.11.047","journal-title":"Fertil Steril"},{"key":"2192_CR129","doi-asserted-by":"publisher","first-page":"e15036","DOI":"10.1371\/journal.pone.0015036","volume":"6","author":"C Foresta","year":"2011","unstructured":"Foresta C, Patassini C, Bertoldo A et al (2011) Mechanism of human papillomavirus binding to human spermatozoa and fertilizing ability of infected spermatozoa. PLoS ONE 6:e15036. https:\/\/doi.org\/10.1371\/journal.pone.0015036","journal-title":"PLoS ONE"},{"key":"2192_CR130","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1016\/j.fertnstert.2011.04.009","volume":"96","author":"C Foresta","year":"2011","unstructured":"Foresta C, Pizzol D, Bertoldo A et al (2011) Semen washing procedures do not eliminate human papilloma virus sperm infection in infertile patients. Fertil Steril 96:1077\u20131082. https:\/\/doi.org\/10.1016\/j.fertnstert.2011.04.009","journal-title":"Fertil Steril"},{"key":"2192_CR131","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1016\/j.fertnstert.2013.06.042","volume":"100","author":"R Schillaci","year":"2013","unstructured":"Schillaci R, Capra G, Bellavia C et al (2013) Detection of oncogenic human papillomavirus genotypes on spermatozoa from male partners of infertile couples. Fertil Steril 100:1236\u20131240. https:\/\/doi.org\/10.1016\/j.fertnstert.2013.06.042","journal-title":"Fertil Steril"},{"key":"2192_CR132","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1038\/aja.2013.36","volume":"15","author":"Y Yang","year":"2013","unstructured":"Yang Y, Jia C-W, Ma Y-M et al (2013) Correlation between HPV sperm infection and male infertility. Asian J Androl 15:529\u2013532. https:\/\/doi.org\/10.1038\/aja.2013.36","journal-title":"Asian J Androl"},{"key":"2192_CR133","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1111\/j.2047-2927.2013.00067.x","volume":"1","author":"MD Kaspersen","year":"2013","unstructured":"Kaspersen MD, Bungum M, Fedder J et al (2013) No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus. Andrology 1:361\u2013364. https:\/\/doi.org\/10.1111\/j.2047-2927.2013.00067.x","journal-title":"Andrology"},{"key":"2192_CR134","doi-asserted-by":"publisher","first-page":"912","DOI":"10.1038\/s41598-018-19369-z","volume":"8","author":"A Garolla","year":"2018","unstructured":"Garolla A, De Toni L, Bottacin A et al (2018) Human Papillomavirus Prophylactic Vaccination improves reproductive outcome in infertile patients with HPV semen infection: a retrospective study. Sci Rep 8:912. https:\/\/doi.org\/10.1038\/s41598-018-19369-z","journal-title":"Sci Rep"},{"key":"2192_CR135","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1093\/humrep\/dey348","volume":"34","author":"L Boeri","year":"2019","unstructured":"Boeri L, Capogrosso P, Ventimiglia E et al (2019) High-risk human papillomavirus in semen is associated with poor sperm progressive motility and a high sperm DNA fragmentation index in infertile men. Hum Reprod 34:209\u2013217. https:\/\/doi.org\/10.1093\/humrep\/dey348","journal-title":"Hum Reprod"},{"key":"2192_CR136","first-page":"183","volume":"21","author":"A Piroozmand","year":"2020","unstructured":"Piroozmand A, Mousavi Nasab SD, Erami M et al (2020) Distribution of human papillomavirus and antisperm antibody in semen and its association with semen parameters among infertile men. J Reprod Infertil 21:183\u2013188","journal-title":"J Reprod Infertil"},{"key":"2192_CR137","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.3390\/cells9051241","volume":"9","author":"G Pellavio","year":"2020","unstructured":"Pellavio G, Todaro F, Alberizzi P et al (2020) HPV infection affects human sperm functionality by inhibition of aquaporin-8. Cells 9:1241. https:\/\/doi.org\/10.3390\/cells9051241","journal-title":"Cells"},{"key":"2192_CR138","doi-asserted-by":"publisher","first-page":"19924","DOI":"10.1038\/s41598-021-99279-9","volume":"11","author":"C Olivera","year":"2021","unstructured":"Olivera C, Mosmann JP, Paira DA et al (2021) Association between Human Papillomavirus and Chlamydia trachomatis genital infections in male partners of infertile couples. Sci Rep 11:19924. https:\/\/doi.org\/10.1038\/s41598-021-99279-9","journal-title":"Sci Rep"},{"key":"2192_CR139","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1080\/13685538.2021.2023126","volume":"25","author":"R Cannarella","year":"2022","unstructured":"Cannarella R, Aversa A, Condorelli RA et al (2022) Impact of seminal low-risk human papillomavirus infection on sperm parameters of adult men. Aging Male 25:17\u201322. https:\/\/doi.org\/10.1080\/13685538.2021.2023126","journal-title":"Aging Male"},{"key":"2192_CR140","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1016\/j.fertnstert.2022.12.002","volume":"119","author":"A Busnelli","year":"2023","unstructured":"Busnelli A, Garolla A, Tersigni C et al (2023) Sperm human papillomavirus infection and risk of idiopathic recurrent pregnancy loss: insights from a multicenter case\u2013control study. Fertil Steril 119:410\u2013418. https:\/\/doi.org\/10.1016\/j.fertnstert.2022.12.002","journal-title":"Fertil Steril"},{"key":"2192_CR141","first-page":"218","volume":"83","author":"A Mlad\u011bnka","year":"2018","unstructured":"Mlad\u011bnka A, Sl\u00e1ma J (2018) Vaccination against HPV and view of new possibilities. Ceska Gynekol 83:218\u2013225","journal-title":"Ceska Gynekol"},{"key":"2192_CR142","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9121413","author":"S Kamolratanakul","year":"2021","unstructured":"Kamolratanakul S, Pitisuttithum P (2021) Human papillomavirus vaccine efficacy and effectiveness against cancer. Vaccines (Basel). https:\/\/doi.org\/10.3390\/vaccines9121413","journal-title":"Vaccines (Basel)"},{"key":"2192_CR143","unstructured":"Soca Gallego L, Dominguez A, Parmar M. Human Papilloma Virus Vaccine. 2023. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2023 Jan\u2013. PMID: 32965857."},{"key":"2192_CR144","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1007\/978-3-030-57362-1_8","volume":"217","author":"E Farmer","year":"2021","unstructured":"Farmer E, Cheng MA, Hung C-F, Wu T-C (2021) Vaccination strategies for the control and treatment of HPV infection and HPV-associated cancer. Recent Results Cancer Res 217:157\u2013195. https:\/\/doi.org\/10.1007\/978-3-030-57362-1_8","journal-title":"Recent Results Cancer Res"},{"key":"2192_CR145","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9111262","author":"DR Boilesen","year":"2021","unstructured":"Boilesen DR, Nielsen KN, Holst PJ (2021) Novel antigenic targets of HPV therapeutic vaccines. Vaccines (Basel). https:\/\/doi.org\/10.3390\/vaccines9111262","journal-title":"Vaccines (Basel)"},{"key":"2192_CR146","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1007\/s13187-019-01681-5","volume":"35","author":"I Thanasas","year":"2020","unstructured":"Thanasas I, Lavranos G, Gkogkou P, Paraskevis D (2020) Understanding of young adolescents about HPV infection: how health education can improve vaccination rate. J Cancer Educ 35:850\u2013859. https:\/\/doi.org\/10.1007\/s13187-019-01681-5","journal-title":"J Cancer Educ"},{"key":"2192_CR147","doi-asserted-by":"publisher","first-page":"219","DOI":"10.5455\/msm.2021.33.219-224","volume":"33","author":"M Iliadou","year":"2021","unstructured":"Iliadou M, Sahini K, Sakellari E et al (2021) What do young people think about HPV and HPV vaccination? The role of health education interventions and health professionals. Mater Sociomed 33:219\u2013224. https:\/\/doi.org\/10.5455\/msm.2021.33.219-224","journal-title":"Mater Sociomed"},{"key":"2192_CR148","doi-asserted-by":"publisher","DOI":"10.1080\/07448481.2020.1865982","author":"I Karki","year":"2021","unstructured":"Karki I, Dobbs PD, Larson D, Maness SB (2021) Human papillomavirus (HPV) knowledge, beliefs, and vaccine uptake among United States and international college students. J Am Coll Health. https:\/\/doi.org\/10.1080\/07448481.2020.1865982","journal-title":"J Am Coll Health"},{"key":"2192_CR149","doi-asserted-by":"publisher","first-page":"1504","DOI":"10.1080\/21645515.2016.1156271","volume":"12","author":"F Napolitano","year":"2016","unstructured":"Napolitano F, Napolitano P, Liguori G, Angelillo IF (2016) Human papillomavirus infection and vaccination: Knowledge and attitudes among young males in Italy. Hum Vaccin Immunother 12:1504\u20131510. https:\/\/doi.org\/10.1080\/21645515.2016.1156271","journal-title":"Hum Vaccin Immunother"},{"key":"2192_CR150","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2022.2109892","author":"EY Du","year":"2022","unstructured":"Du EY, Adjei Boakye E, Taylor DB et al (2022) Medical students\u2019 knowledge of HPV, HPV vaccine, and HPV-associated head and neck cancer. Hum Vaccin Immunother. https:\/\/doi.org\/10.1080\/21645515.2022.2109892","journal-title":"Hum Vaccin Immunother"},{"key":"2192_CR151","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1080\/21645515.2020.1783952","volume":"17","author":"OG Chido-Amajuoyi","year":"2021","unstructured":"Chido-Amajuoyi OG, Jackson I, Yu R, Shete S (2021) Declining awareness of HPV and HPV vaccine within the general US population. Hum Vaccin Immunother 17:420\u2013427. https:\/\/doi.org\/10.1080\/21645515.2020.1783952","journal-title":"Hum Vaccin Immunother"},{"key":"2192_CR152","doi-asserted-by":"publisher","first-page":"1465","DOI":"10.1080\/21645515.2019.1581543","volume":"15","author":"RR Ortiz","year":"2019","unstructured":"Ortiz RR, Smith A, Coyne-Beasley T (2019) A systematic literature review to examine the potential for social media to impact HPV vaccine uptake and awareness, knowledge, and attitudes about HPV and HPV vaccination. Hum Vaccin Immunother 15:1465\u20131475. https:\/\/doi.org\/10.1080\/21645515.2019.1581543","journal-title":"Hum Vaccin Immunother"},{"key":"2192_CR153","first-page":"S19","volume":"111","author":"CA Dietz","year":"2011","unstructured":"Dietz CA, Nyberg CR (2011) Genital, oral, and anal human papillomavirus infection in men who have sex with men. J Am Osteopath Assoc 111:S19-25","journal-title":"J Am Osteopath Assoc"}],"container-title":["Journal of Endocrinological Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40618-023-02192-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40618-023-02192-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40618-023-02192-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T21:35:59Z","timestamp":1708032959000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40618-023-02192-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,28]]},"references-count":153,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,2]]}},"alternative-id":["2192"],"URL":"https:\/\/doi.org\/10.1007\/s40618-023-02192-3","relation":{},"ISSN":["1720-8386"],"issn-type":[{"value":"1720-8386","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,28]]},"assertion":[{"value":"21 June 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 September 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers\u2019 bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This is a narrative review of the literature not involving human participants and\/or animals. The Research Ethics Committee has confirmed that no ethical approval is required.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Research involving human participants and\/or animals"}},{"value":"Since the research does not involve human participants and\/or animals, no informed consent is required.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}