{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T17:26:28Z","timestamp":1762881988803,"version":"3.45.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T00:00:00Z","timestamp":1753315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T00:00:00Z","timestamp":1753315200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100018554","name":"Science and Technology Program of Gansu Province","doi-asserted-by":"publisher","award":["23YFFA0048"],"award-info":[{"award-number":["23YFFA0048"]}],"id":[{"id":"10.13039\/501100018554","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Endocrinol Invest"],"DOI":"10.1007\/s40618-025-02658-6","type":"journal-article","created":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T06:30:12Z","timestamp":1753338612000},"page":"2615-2624","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Characteristic volume, texture, and functional connectivity alterations in hypothalamic subunits of adult primary hypothyroidism: a multiparametric MRI analysis"],"prefix":"10.1007","volume":"48","author":[{"given":"Liting","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiancang","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinghe","family":"Tian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huiyan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenwen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1170-771X","authenticated-orcid":false,"given":"Lianping","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,7,24]]},"reference":[{"key":"2658_CR1","doi-asserted-by":"publisher","unstructured":"Chaker L, Razvi S, Bensenor IM, Azizi F, Pearce EN, Peeters RP (2022) Hypothyroidism. Nat Reviews Disease Primers 8(1). https:\/\/doi.org\/10.1038\/s41572-022-00357-7","DOI":"10.1038\/s41572-022-00357-7"},{"issue":"2","key":"2658_CR2","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1001\/jama.2019.9052","volume":"322","author":"B Biondi","year":"2019","unstructured":"Biondi B, Cappola AR, Cooper DS (2019) Subclinical hypothyroidism: A review. JAMA 322(2):153\u2013160. https:\/\/doi.org\/10.1001\/jama.2019.9052","journal-title":"JAMA"},{"key":"2658_CR3","doi-asserted-by":"publisher","unstructured":"Kotwal A, Cortes T, Genere N, Hamidi O, Jasim S, Newman CB et al (2020) Treatment of thyroid dysfunction and serum lipids: A systematic review and Meta-analysis. J Clin Endocrinol Metab 105(12). https:\/\/doi.org\/10.1210\/clinem\/dgaa672","DOI":"10.1210\/clinem\/dgaa672"},{"key":"2658_CR4","doi-asserted-by":"publisher","first-page":"111173","DOI":"10.1016\/j.mce.2021.111173","volume":"525","author":"U Feldt-Rasmussen","year":"2021","unstructured":"Feldt-Rasmussen U, Effraimidis G, Klose M (2021) The hypothalamus-pituitary-thyroid (HPT)-axis and its role in physiology and pathophysiology of other hypothalamus-pituitary functions. Mol Cell Endocrinol 525:111173. https:\/\/doi.org\/10.1016\/j.mce.2021.111173","journal-title":"Mol Cell Endocrinol"},{"key":"2658_CR5","doi-asserted-by":"publisher","first-page":"105567","DOI":"10.1016\/j.nbd.2021.105567","volume":"162","author":"V Valc\u00e1rcel-Hern\u00e1ndez","year":"2022","unstructured":"Valc\u00e1rcel-Hern\u00e1ndez V, L\u00f3pez-Esp\u00edndola D, Guill\u00e9n-Yunta M, Garc\u00eda-Aldea \u00c1, L\u00f3pez de Toledo Soler I, B\u00e1rez-L\u00f3pez S et al (2022) Deficient thyroid hormone transport to the brain leads to impairments in axonal caliber and oligodendroglial development. Neurobiol Dis 162:105567. https:\/\/doi.org\/10.1016\/j.nbd.2021.105567","journal-title":"Neurobiol Dis"},{"key":"2658_CR6","doi-asserted-by":"publisher","first-page":"105548","DOI":"10.1016\/j.yhbeh.2024.105548","volume":"162","author":"Z Zare","year":"2024","unstructured":"Zare Z, Shafia S, Mohammadi M (2024) Thyroid hormone deficiency affects anxiety-related behaviors and expression of hippocampal glutamate transporters in male congenital hypothyroid rat offspring. Horm Behav 162:105548. https:\/\/doi.org\/10.1016\/j.yhbeh.2024.105548","journal-title":"Horm Behav"},{"key":"2658_CR7","doi-asserted-by":"publisher","first-page":"725908","DOI":"10.3389\/fnbeh.2021.725908","volume":"15","author":"J Yin","year":"2021","unstructured":"Yin J, Xie L, Luo D, Huang J, Guo R, Zheng Y et al (2021) Changes of structural and functional attention control networks in subclinical hypothyroidism. Front Behav Neurosci 15:725908. https:\/\/doi.org\/10.3389\/fnbeh.2021.725908","journal-title":"Front Behav Neurosci"},{"issue":"7","key":"2658_CR8","doi-asserted-by":"publisher","first-page":"1707","DOI":"10.1210\/clinem\/dgae070","volume":"109","author":"T Zhang","year":"2024","unstructured":"Zhang T, Zhao L, Chen C, Yang C, Zhang H, Su W et al (2024) Structural and functional alterations of hippocampal subfields in patients with Adult-Onset primary hypothyroidism. J Clin Endocrinol Metab 109(7):1707\u20131717. https:\/\/doi.org\/10.1210\/clinem\/dgae070","journal-title":"J Clin Endocrinol Metab"},{"issue":"12","key":"2658_CR9","doi-asserted-by":"publisher","first-page":"e1496","DOI":"10.1210\/clinem\/dgad391","volume":"108","author":"JCR Rojas-Ramos","year":"2023","unstructured":"Rojas-Ramos JCR, Pelaez JM, Ono SE, Ramos CS, de Carvalho Neto A, de Lacerda L et al (2023) Cerebral cortical thickness morphometry and neurocognitive correlations in adolescents with congenital hypothyroidism. J Clin Endocrinol Metab 108(12):e1496\u2013e1505. https:\/\/doi.org\/10.1210\/clinem\/dgad391","journal-title":"J Clin Endocrinol Metab"},{"issue":"7","key":"2658_CR10","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1089\/thy.2022.0476","volume":"33","author":"W Su","year":"2023","unstructured":"Su W, Zhao L, Bao S, Qin R, Cao J, Tian J et al (2023) Alterations in Gray matter morphology and functional connectivity in adult patients with newly diagnosed untreated hypothyroidism. Thyroid 33(7):791\u2013803. https:\/\/doi.org\/10.1089\/thy.2022.0476","journal-title":"Thyroid"},{"issue":"1","key":"2658_CR11","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1503\/jpn.180171","volume":"45","author":"S Lee","year":"2020","unstructured":"Lee S, Lee H, Kim KW (2020) Magnetic resonance imaging texture predicts progression to dementia due to alzheimer disease earlier than hippocampal volume. J Psychiatry Neurosci 45(1):7\u201314. https:\/\/doi.org\/10.1503\/jpn.180171","journal-title":"J Psychiatry Neurosci"},{"issue":"12","key":"2658_CR12","doi-asserted-by":"publisher","first-page":"5309","DOI":"10.1038\/s41380-023-02163-3","volume":"28","author":"SY Moon","year":"2023","unstructured":"Moon SY, Park H, Lee W, Lee S, Lho SK, Kim M et al (2023) Magnetic resonance texture analysis reveals stagewise nonlinear alterations of the frontal Gray matter in patients with early psychosis. Mol Psychiatry 28(12):5309\u20135318. https:\/\/doi.org\/10.1038\/s41380-023-02163-3","journal-title":"Mol Psychiatry"},{"key":"2658_CR13","doi-asserted-by":"publisher","first-page":"110055","DOI":"10.1016\/j.ejrad.2021.110055","volume":"146","author":"G Corrias","year":"2022","unstructured":"Corrias G, Micheletti G, Barberini L, Suri JS, Saba L (2022) Texture analysis imaging what a clinical radiologist needs to know. Eur J Radiol 146:110055. https:\/\/doi.org\/10.1016\/j.ejrad.2021.110055","journal-title":"Eur J Radiol"},{"issue":"49","key":"2658_CR14","doi-asserted-by":"publisher","first-page":"8275","DOI":"10.1523\/jneurosci.1043-23.2023","volume":"43","author":"C Millevert","year":"2023","unstructured":"Millevert C, Vidas-Guscic N, Vanherp L, Jonckers E, Verhoye M, Staelens S et al (2023) Resting-State functional MRI and PET imaging as noninvasive tools to study (Ab)Normal neurodevelopment in humans and rodents. J Neurosci 43(49):8275\u20138293. https:\/\/doi.org\/10.1523\/jneurosci.1043-23.2023","journal-title":"J Neurosci"},{"issue":"2","key":"2658_CR15","first-page":"167","volume":"33","author":"A EBoCM","year":"2017","unstructured":"EBoCM A (2017) Guidelines for the diagnosis and treatment of adult hypothyroidism. Chin J Endocrinol Metab 33(2):167\u2013180","journal-title":"Chin J Endocrinol Metab"},{"key":"2658_CR16","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1186\/1471-244x-12-156","volume":"12","author":"J Yu","year":"2012","unstructured":"Yu J, Li J, Huang X (2012) The Beijing version of the Montreal cognitive assessment as a brief screening tool for mild cognitive impairment: a community-based study. BMC Psychiatry 12:156. https:\/\/doi.org\/10.1186\/1471-244x-12-156","journal-title":"BMC Psychiatry"},{"issue":"1","key":"2658_CR17","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/0165-0327(88)90072-9","volume":"14","author":"W Maier","year":"1988","unstructured":"Maier W, Buller R, Philipp M, Heuser I (1988) The Hamilton anxiety scale: reliability, validity and sensitivity to change in anxiety and depressive disorders. J Affect Disord 14(1):61\u201368. https:\/\/doi.org\/10.1016\/0165-0327(88)90072-9","journal-title":"J Affect Disord"},{"issue":"1","key":"2658_CR18","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","volume":"23","author":"M Hamilton","year":"1960","unstructured":"Hamilton M (1960) A rating scale for depression. J Neurol Neurosurg Psychiatry 23(1):56\u201362. https:\/\/doi.org\/10.1136\/jnnp.23.1.56","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2658_CR19","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1016\/j.neuroimage.2013.05.099","volume":"83","author":"RM Birn","year":"2013","unstructured":"Birn RM, Molloy EK, Patriat R, Parker T, Meier TB, Kirk GR et al (2013) The effect of scan length on the reliability of resting-state fMRI connectivity estimates. NeuroImage 83:550\u2013558. https:\/\/doi.org\/10.1016\/j.neuroimage.2013.05.099","journal-title":"NeuroImage"},{"issue":"3","key":"2658_CR20","doi-asserted-by":"publisher","first-page":"548","DOI":"10.3174\/ajnr.A2330","volume":"32","author":"JS Anderson","year":"2011","unstructured":"Anderson JS, Ferguson MA, Lopez-Larson M, Yurgelun-Todd D (2011) Reproducibility of single-subject functional connectivity measurements. AJNR Am J Neuroradiol 32(3):548\u2013555. https:\/\/doi.org\/10.3174\/ajnr.A2330","journal-title":"AJNR Am J Neuroradiol"},{"key":"2658_CR21","doi-asserted-by":"publisher","first-page":"117287","DOI":"10.1016\/j.neuroimage.2020.117287","volume":"223","author":"B Billot","year":"2020","unstructured":"Billot B, Bocchetta M, Todd E, Dalca AV, Rohrer JD, Iglesias JE (2020) Automated segmentation of the hypothalamus and associated subunits in brain MRI. NeuroImage 223:117287. https:\/\/doi.org\/10.1016\/j.neuroimage.2020.117287","journal-title":"NeuroImage"},{"issue":"8","key":"2658_CR22","doi-asserted-by":"publisher","first-page":"e0237587","DOI":"10.1371\/journal.pone.0237587","volume":"15","author":"Y Song","year":"2020","unstructured":"Song Y, Zhang J, Zhang YD, Hou Y, Yan X, Wang Y et al (2020) FeAture explorer (FAE): A tool for developing and comparing radiomics models. PLoS ONE 15(8):e0237587. https:\/\/doi.org\/10.1371\/journal.pone.0237587","journal-title":"PLoS ONE"},{"issue":"1","key":"2658_CR23","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1530\/joe-20-0026","volume":"246","author":"S Luan","year":"2020","unstructured":"Luan S, Bi W, Shi S, Peng L, Li Z, Jiang J et al (2020) Thyrotropin receptor signaling deficiency impairs Spatial learning and memory in mice. J Endocrinol 246(1):41\u201355. https:\/\/doi.org\/10.1530\/joe-20-0026","journal-title":"J Endocrinol"},{"key":"2658_CR24","doi-asserted-by":"publisher","unstructured":"G\u0142ombik K, Detka J, Bobula B, B\u0105k J, Kusek M, Tokarski K et al (2021) Contribution of hypothyroidism to cognitive impairment and hippocampal synaptic plasticity regulation in an animal model of depression. Int J Mol Sci 22(4). https:\/\/doi.org\/10.3390\/ijms22041599","DOI":"10.3390\/ijms22041599"},{"issue":"1","key":"2658_CR25","doi-asserted-by":"publisher","first-page":"89","DOI":"10.20945\/2359-3997000000201","volume":"64","author":"A Batistuzzo","year":"2020","unstructured":"Batistuzzo A, Ribeiro MO (2020) Clinical and subclinical maternal hypothyroidism and their effects on neurodevelopment, behavior and cognition. Arch Endocrinol Metab 64(1):89\u201395. https:\/\/doi.org\/10.20945\/2359-3997000000201","journal-title":"Arch Endocrinol Metab"},{"issue":"1","key":"2658_CR26","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/s13293-021-00367-2","volume":"12","author":"S Baksi","year":"2021","unstructured":"Baksi S, Pradhan A (2021) Thyroid hormone: sex-dependent role in nervous system regulation and disease. Biol Sex Differ 12(1):25. https:\/\/doi.org\/10.1186\/s13293-021-00367-2","journal-title":"Biol Sex Differ"},{"key":"2658_CR27","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.mce.2017.01.018","volume":"458","author":"Z Zhang","year":"2017","unstructured":"Zhang Z, Boelen A, Bisschop PH, Kalsbeek A, Fliers E (2017) Hypothalamic effects of thyroid hormone. Mol Cell Endocrinol 458:143\u2013148. https:\/\/doi.org\/10.1016\/j.mce.2017.01.018","journal-title":"Mol Cell Endocrinol"},{"issue":"6","key":"2658_CR28","doi-asserted-by":"publisher","first-page":"e2415970122","DOI":"10.1073\/pnas.2415970122","volume":"122","author":"R Sink\u00f3","year":"2025","unstructured":"Sink\u00f3 R, Salas-Lucia F, Moh\u00e1csik P, Halmos E, Wittmann G, Egri P et al (2025) Variable transduction of thyroid hormone signaling in structures of the mouse brain. Proc Natl Acad Sci U S A 122(6):e2415970122. https:\/\/doi.org\/10.1073\/pnas.2415970122","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"12","key":"2658_CR29","doi-asserted-by":"publisher","first-page":"2635","DOI":"10.1007\/s00415-015-7885-2","volume":"262","author":"M Bocchetta","year":"2015","unstructured":"Bocchetta M, Gordon E, Manning E, Barnes J, Cash DM, Espak M et al (2015) Detailed volumetric analysis of the hypothalamus in behavioral variant frontotemporal dementia. J Neurol 262(12):2635\u20132642. https:\/\/doi.org\/10.1007\/s00415-015-7885-2","journal-title":"J Neurol"},{"issue":"19","key":"2658_CR30","doi-asserted-by":"publisher","first-page":"4865","DOI":"10.1113\/jp286449","volume":"602","author":"F Emrich","year":"2024","unstructured":"Emrich F, Gomes BH, Selvatici-Tolentino L, Lopes RA, Secio-Silva A, Carvalho-Moreira JP et al (2024) Hypothyroidism alters the rhythmicity of the central clock, body temperature and metabolism: evidence of Bmal1 transcriptional regulation by T3. J Physiol 602(19):4865\u20134887. https:\/\/doi.org\/10.1113\/jp286449","journal-title":"J Physiol"},{"key":"2658_CR31","doi-asserted-by":"publisher","first-page":"118809","DOI":"10.1016\/j.lfs.2020.118809","volume":"265","author":"E Pitsillou","year":"2021","unstructured":"Pitsillou E, Liang J, Hung A, Karagiannis TC (2021) The circadian machinery links metabolic disorders and depression: A review of pathways, proteins and potential Pharmacological interventions. Life Sci 265:118809. https:\/\/doi.org\/10.1016\/j.lfs.2020.118809","journal-title":"Life Sci"},{"issue":"2","key":"2658_CR32","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1210\/jc.2009-1959","volume":"95","author":"F Roelfsema","year":"2010","unstructured":"Roelfsema F, Pereira AM, Adriaanse R, Endert E, Fliers E, Romijn JA et al (2010) Thyrotropin secretion in mild and severe primary hypothyroidism is distinguished by amplified burst mass and basal secretion with increased spikiness and approximate entropy. J Clin Endocrinol Metab 95(2):928\u2013934. https:\/\/doi.org\/10.1210\/jc.2009-1959","journal-title":"J Clin Endocrinol Metab"},{"issue":"2\u20133","key":"2658_CR33","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1016\/0306-4522(91)90373-v","volume":"41","author":"MD Madeira","year":"1991","unstructured":"Madeira MD, Cadete-Leite A, Sousa N, Paula-Barbosa MM (1991) The supraoptic nucleus in hypothyroid and undernourished rats: an experimental morphometric study. Neuroscience 41(2\u20133):827\u2013839. https:\/\/doi.org\/10.1016\/0306-4522(91)90373-v","journal-title":"Neuroscience"},{"key":"2658_CR34","doi-asserted-by":"publisher","unstructured":"Reid M (2022) P657. Cerebellum structural covariance networks in PTSD and depression. Biol Psychiatry 91(9). https:\/\/doi.org\/10.1016\/j.biopsych.2022.02.894","DOI":"10.1016\/j.biopsych.2022.02.894"},{"issue":"4","key":"2658_CR35","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1159\/000535860","volume":"114","author":"HY Zhang","year":"2024","unstructured":"Zhang HY, Shen G, Yang C, Tan J, Cao JC, Tian J et al (2024) The reduced Gray matter volume and functional connectivity of the cerebellum in type 2 diabetes mellitus with high insulin resistance. Neuroendocrinology 114(4):386\u2013399. https:\/\/doi.org\/10.1159\/000535860","journal-title":"Neuroendocrinology"},{"key":"2658_CR36","doi-asserted-by":"publisher","first-page":"287","DOI":"10.3389\/fpsyt.2018.00287","volume":"9","author":"C Wu","year":"2018","unstructured":"Wu C, Zheng Y, Li J, She S, Peng H, Li L (2018) Cortical Gray matter loss, augmented vulnerability to Speech-on-Speech masking, and delusion in people with schizophrenia. Front Psychiatry 9:287. https:\/\/doi.org\/10.3389\/fpsyt.2018.00287","journal-title":"Front Psychiatry"},{"issue":"3","key":"2658_CR37","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1016\/j.brs.2021.03.014","volume":"14","author":"I Iarrobino","year":"2021","unstructured":"Iarrobino I, Bongiardina A, Monte D, Sarasso O, Ronga P, Neppi-Modona I, M., et al (2021) Right and left inferior frontal opercula are involved in discriminating angry and sad facial expressions. Brain Stimul 14(3):607\u2013615. https:\/\/doi.org\/10.1016\/j.brs.2021.03.014","journal-title":"Brain Stimul"},{"issue":"1","key":"2658_CR38","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1503\/jpn.180162","volume":"45","author":"S Wang","year":"2020","unstructured":"Wang S, Gong G, Zhong S, Duan J, Yin Z, Chang M et al (2020) Neurobiological commonalities and distinctions among 3 major psychiatric disorders: a graph theoretical analysis of the structural connectome. J Psychiatry Neurosci 45(1):15\u201322. https:\/\/doi.org\/10.1503\/jpn.180162","journal-title":"J Psychiatry Neurosci"},{"key":"2658_CR39","doi-asserted-by":"publisher","first-page":"465","DOI":"10.3389\/fpsyt.2019.00465","volume":"10","author":"X Li","year":"2019","unstructured":"Li X, Zhang M, Li K, Zou F, Wang Y, Wu X et al (2019) The altered somatic brain network in state anxiety. Front Psychiatry 10:465. https:\/\/doi.org\/10.3389\/fpsyt.2019.00465","journal-title":"Front Psychiatry"},{"issue":"2","key":"2658_CR40","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1111\/cns.13775","volume":"28","author":"WY Ma","year":"2022","unstructured":"Ma WY, Tian MJ, Yao Q, Li Q, Tang FY, Xiao CY et al (2022) Neuroimaging alterations in dementia with lewy bodies and neuroimaging differences between dementia with lewy bodies and alzheimer\u2019s disease: an activation likelihood Estimation meta-analysis. CNS Neurosci Ther 28(2):183\u2013205. https:\/\/doi.org\/10.1111\/cns.13775","journal-title":"CNS Neurosci Ther"},{"key":"2658_CR41","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1016\/j.neuroscience.2023.11.003","volume":"535","author":"S Feng","year":"2023","unstructured":"Feng S, Yao H, Zheng S, Feng Z, Liu X, Liu R et al (2023) Altered functional connectivity in working memory network after acute sleep deprivation. Neuroscience 535:158\u2013167. https:\/\/doi.org\/10.1016\/j.neuroscience.2023.11.003","journal-title":"Neuroscience"},{"key":"2658_CR42","doi-asserted-by":"publisher","DOI":"10.1111\/jne.12587","author":"M Kumar","year":"2018","unstructured":"Kumar M, Modi S, Rana P, Kumar P, Kanwar R, Sekhri T et al (2018) Alteration in intrinsic and extrinsic functional connectivity of resting state networks associated with subclinical hypothyroid. J Neuroendocrinol. https:\/\/doi.org\/10.1111\/jne.12587","journal-title":"J Neuroendocrinol"}],"container-title":["Journal of Endocrinological Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40618-025-02658-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40618-025-02658-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40618-025-02658-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T17:21:38Z","timestamp":1762881698000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40618-025-02658-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,24]]},"references-count":42,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2025,11]]}},"alternative-id":["2658"],"URL":"https:\/\/doi.org\/10.1007\/s40618-025-02658-6","relation":{},"ISSN":["1720-8386"],"issn-type":[{"type":"electronic","value":"1720-8386"}],"subject":[],"published":{"date-parts":[[2025,7,24]]},"assertion":[{"value":"24 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was performed in line with the principles of the Declaration of Helsinki. Approved by the Ethics Committee of Gansu Provincial Hospital (Approval No.2019-96, 2023-500). All participants in this study signed informed consent to participate.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All participants included in this study provided written informed consent for the publication of their anonymized data. The consent forms are retained by the authors and are available for review by the editor if requested.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}