{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T09:05:02Z","timestamp":1790759102070,"version":"4.1.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"The Science and Technology Development Special Fund Competitive Allocation Project of Zhanjiang City","award":["2021A05088"],"award-info":[{"award-number":["2021A05088"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Endocrinol Invest"],"DOI":"10.1007\/s40618-026-02975-4","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T11:54:01Z","timestamp":1783511641000},"page":"3053-3062","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Delirium in diabetic ketoacidosis: a multicenter observational study of occurrence, associated factors and outcomes from 578,204 hospitalizations"],"prefix":"10.1007","volume":"49","author":[{"given":"Songlin","family":"Xie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jincong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weifeng","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junfen","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengzhao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiongtian","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhangaixi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junde","family":"Mo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5972-7237","authenticated-orcid":false,"given":"Binbin","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kangjie","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,8]]},"reference":[{"issue":"7","key":"2975_CR1","doi-asserted-by":"publisher","first-page":"1162","DOI":"10.1111\/jdi.13452","volume":"12","author":"SF Awad","year":"2021","unstructured":"Awad SF, Al-Mawali A, Al-Lawati JA, Morsi M, Critchley JA, Abu-Raddad LJ (2021) Forecasting the type 2 diabetes mellitus epidemic and the role of key risk factors in Oman up to 2050: mathematical modeling analyses. J Diabetes Investig 12(7):1162\u20131174","journal-title":"J Diabetes Investig"},{"key":"2975_CR2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1597365","volume":"16","author":"N Tian","year":"2025","unstructured":"Tian N, Yang Y, Liu Q, Ma Z, Wang Y, Li X, Wang X, Jin Y, Chen R, Li Y et al (2025) DKA with negative DM-autoantibodies, complicated by GBS and RESLES: a case report and literature review. Front Immunol 16:1597365","journal-title":"Front Immunol"},{"key":"2975_CR3","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.ejim.2023.07.005","volume":"117","author":"L Barski","year":"2023","unstructured":"Barski L, Golbets E, Jotkowitz A, Schwarzfuchs D (2023) Management of diabetic ketoacidosis. Eur J Intern Med 117:38\u201344","journal-title":"Eur J Intern Med"},{"issue":"4","key":"2975_CR4","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1056\/NEJM200101253440404","volume":"344","author":"N Glaser","year":"2001","unstructured":"Glaser N, Barnett P, McCaslin I, Nelson D, Trainor J, Louie J, Kaufman F, Quayle K, Roback M, Malley R et al (2001) Risk factors for cerebral edema in children with diabetic ketoacidosis. The pediatric emergency medicine collaborative research committee of the american academy of pediatrics. N Engl J Med 344(4):264\u2013269","journal-title":"N Engl J Med"},{"issue":"10","key":"2975_CR5","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1007\/s00134-021-06503-1","volume":"47","author":"JL Stollings","year":"2021","unstructured":"Stollings JL, Kotfis K, Chanques G, Pun BT, Pandharipande PP, Ely EW (2021) Delirium in critical illness: clinical manifestations, outcomes, and management. Intensive Care Med 47(10):1089\u20131103","journal-title":"Intensive Care Med"},{"issue":"4","key":"2975_CR6","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1046\/j.1525-1497.1998.00073.x","volume":"13","author":"SK Inouye","year":"1998","unstructured":"Inouye SK, Rushing JT, Foreman MD, Palmer RM, Pompei P (1998) Does delirium contribute to poor hospital outcomes? A three-site epidemiologic study. J Gen Intern Med 13(4):234\u2013242","journal-title":"J Gen Intern Med"},{"issue":"4","key":"2975_CR7","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1001\/jama.2010.1013","volume":"304","author":"J Witlox","year":"2010","unstructured":"Witlox J, Eurelings LS, de Jonghe JF, Kalisvaart KJ, Eikelenboom P, van Gool WA (2010) Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: a meta-analysis. JAMA 304(4):443\u2013451","journal-title":"JAMA"},{"issue":"4","key":"2975_CR8","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1038\/nrendo.2016.15","volume":"12","author":"G Umpierrez","year":"2016","unstructured":"Umpierrez G, Korytkowski M (2016) Diabetic emergencies - ketoacidosis, hyperglycaemic hyperosmolar state and hypoglycaemia. Nat Rev Endocrinol 12(4):222\u2013232","journal-title":"Nat Rev Endocrinol"},{"key":"2975_CR9","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0000000000002630","author":"B Tian","year":"2025","unstructured":"Tian B, Chen C, Cheng J, Wang J, Mo J, Zhong G, Lu Y (2025) Predictors, morbidity, and healthcare costs of acute kidney injury in diabetic ketoacidosis: a decade-long retrospective cohort study of 464,057 US hospitalizations. Shock. https:\/\/doi.org\/10.1097\/SHK.0000000000002630","journal-title":"Shock"},{"issue":"1","key":"2975_CR10","doi-asserted-by":"publisher","first-page":"39","DOI":"10.4274\/Jcrpe.478","volume":"4","author":"AN Cebeci","year":"2012","unstructured":"Cebeci AN, G\u00fcven A (2012) Delirium in diabetic ketoacidosis: a case report. J Clin Res Pediatr Endocrinol 4(1):39\u201341","journal-title":"J Clin Res Pediatr Endocrinol"},{"issue":"1","key":"2975_CR11","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1186\/s13098-025-01972-6","volume":"17","author":"B Tian","year":"2025","unstructured":"Tian B, Cao X, Cheng J, Wang J, Shen P, Mo J, Zhong G, Zhang G (2025) Aspiration pneumonia in diabetic ketoacidosis: a decade-long analysis of occurrence, associated risk factors and clinical outcomes in 530,700 US hospitalizations. Diabetol Metab Syndr 17(1):395","journal-title":"Diabetol Metab Syndr"},{"issue":"6","key":"2975_CR12","doi-asserted-by":"publisher","first-page":"878","DOI":"10.1097\/SHK.0000000000002577","volume":"63","author":"B Tian","year":"2025","unstructured":"Tian B, Tang X, He L, Cheng J, Wang J, Liang S, Mo J, Chen C (2025) Predictors and outcomes of acute kidney injury in intracerebral hemorrhage patients: evidence from a large-scale national database analysis. Shock 63(6):878\u2013884","journal-title":"Shock"},{"issue":"5","key":"2975_CR13","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1111\/acps.13473","volume":"147","author":"J Luccarelli","year":"2023","unstructured":"Luccarelli J, Kalluri AS, Thom RP, Hazen EP, Pinsky E, McCoy TH Jr. (2023) The occurrence of delirium diagnosis among youth hospitalizations in the United States: a Kids\u2019 Inpatient Database analysis. Acta Psychiatr Scand 147(5):481\u2013492","journal-title":"Acta Psychiatr Scand"},{"issue":"7","key":"2975_CR14","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1002\/clc.22972","volume":"41","author":"A Abdullah","year":"2018","unstructured":"Abdullah A, Eigbire G, Salama A, Wahab A, Awadalla M, Hoefen R, Alweis R (2018) Impact of delirium on patients hospitalized for myocardial infarction: a propensity score analysis of the National Inpatient Sample. Clin Cardiol 41(7):910\u2013915","journal-title":"Clin Cardiol"},{"issue":"8","key":"2975_CR15","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1002\/pds.4226","volume":"26","author":"DH Kim","year":"2017","unstructured":"Kim DH, Lee J, Kim CA, Huybrechts KF, Bateman BT, Patorno E, Marcantonio ER (2017) Evaluation of algorithms to identify delirium in administrative claims and drug utilization database. Pharmacoepidemiol Drug Saf 26(8):945\u2013953","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"2975_CR16","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afae006","author":"I Titlestad","year":"2024","unstructured":"Titlestad I, Haugarvoll K, Solvang SH, Norekv\u00e5l TM, Skogseth RE, Andreassen OA, \u00c5rsland D, Neerland BE, Nordrehaug JE, Tell GS et al (2024) Delirium is frequently underdiagnosed among older hospitalised patients despite available information in hospital medical records. Age Ageing. https:\/\/doi.org\/10.1093\/ageing\/afae006","journal-title":"Age Ageing"},{"issue":"1","key":"2975_CR17","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1186\/s12902-019-0398-8","volume":"19","author":"M Tomkins","year":"2019","unstructured":"Tomkins M, McCormack R, O\u2019Connell K, Agha A, Merwick \u00c1 (2019) Metabolic encephalopathy secondary to diabetic ketoacidosis: a case report. BMC Endocr Disord 19(1):71","journal-title":"BMC Endocr Disord"},{"key":"2975_CR18","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/416792","author":"V Peritogiannis","year":"2015","unstructured":"Peritogiannis V, Bolosi M, Lixouriotis C, Rizos DV (2015) Recent insights on prevalence and corelations of hypoactive delirium. Behav Neurol. https:\/\/doi.org\/10.1155\/2015\/416792","journal-title":"Behav Neurol"},{"issue":"1","key":"2975_CR19","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-025-03263-3","volume":"25","author":"X Qi","year":"2025","unstructured":"Qi X, Liu C, Liao B, Wang X, Wu Y, Liao Y, Lin L, Bai X, Wang Z, Ding H (2025) Incidence and risk factors of postoperative delirium in patients undergoing elective lung cancer surgery: a retrospective study using the national inpatient sample database. BMC Surg 25(1):509","journal-title":"BMC Surg"},{"issue":"1","key":"2975_CR20","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1186\/s12893-024-02436-w","volume":"24","author":"R Liu","year":"2024","unstructured":"Liu R, Liu N, Suo S, Yang Q, Deng Z, Fu W, Wang M (2024) Incidence and risk factors of postoperative delirium following hepatic resection: a retrospective national inpatient sample database study. BMC Surg 24(1):151","journal-title":"BMC Surg"},{"issue":"1","key":"2975_CR21","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-024-07757-8","volume":"25","author":"Z Peng","year":"2024","unstructured":"Peng Z, Wu J, Wang Z, Xie H, Wang J, Zhang P, Yang Q, Luo Y (2024) Incidence and related risk factors for postoperative delirium following revision total knee arthroplasty: a retrospective nationwide inpatient sample database study. BMC Musculoskelet Disord 25(1):633","journal-title":"BMC Musculoskelet Disord"},{"issue":"1","key":"2975_CR22","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1186\/s12888-023-04576-4","volume":"23","author":"Q Yang","year":"2023","unstructured":"Yang Q, Fu J, Pan X, Shi D, Li K, Sun M, Ding J, Shi Z, Wang J (2023) A retrospective analysis of the incidence of postoperative delirium and the importance of database selection for its definition. BMC Psychiatry 23(1):88","journal-title":"BMC Psychiatry"},{"issue":"1","key":"2975_CR23","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1186\/s12888-020-02742-6","volume":"20","author":"Q Yang","year":"2020","unstructured":"Yang Q, Wang J, Huang X, Xu Y, Zhang Y (2020) Incidence and risk factors associated with postoperative delirium following primary elective total hip arthroplasty: a retrospective nationwide inpatient sample database study. BMC Psychiatry 20(1):343","journal-title":"BMC Psychiatry"},{"issue":"1","key":"2975_CR24","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-020-00223-4","volume":"6","author":"JE Wilson","year":"2020","unstructured":"Wilson JE, Mart MF, Cunningham C, Shehabi Y, Girard TD, MacLullich AMJ, Slooter AJC, Ely EW (2020) Delirium. Nat Rev Dis Primers 6(1):90","journal-title":"Nat Rev Dis Primers"},{"issue":"6","key":"2975_CR25","doi-asserted-by":"publisher","first-page":"1977","DOI":"10.1053\/j.jvca.2017.03.016","volume":"31","author":"A Soundhar","year":"2017","unstructured":"Soundhar A, Udesh R, Mehta A, Schindler J, Jeevanantham V, Gleason T, Thirumala PD (2017) Delirium following transcatheter aortic valve replacement: national inpatient sample analysis. J Cardiothorac Vasc Anesth 31(6):1977\u20131984","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"11","key":"2975_CR26","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1080\/02699052.2016.1193631","volume":"30","author":"RC Turner","year":"2016","unstructured":"Turner RC, Lucke-Wold BP, Robson MJ, Lee JM, Bailes JE (2016) Alzheimer\u2019s disease and chronic traumatic encephalopathy: distinct but possibly overlapping disease entities. Brain Inj 30(11):1279\u20131292","journal-title":"Brain Inj"},{"issue":"2","key":"2975_CR27","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1161\/CIRCULATIONAHA.108.795260","volume":"119","author":"JL Rudolph","year":"2009","unstructured":"Rudolph JL, Jones RN, Levkoff SE, Rockett C, Inouye SK, Sellke FW, Khuri SF, Lipsitz LA, Ramlawi B, Levitsky S et al (2009) Derivation and validation of a preoperative prediction rule for delirium after cardiac surgery. Circulation 119(2):229\u2013236","journal-title":"Circulation"},{"key":"2975_CR28","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2318-11-34","volume":"11","author":"A de Jonghe","year":"2011","unstructured":"de Jonghe A, van Munster BC, van Oosten HE, Goslings JC, Kloen P, van Rees C, Wolvius R, van Velde R, Levi MM, Korevaar JC et al (2011) The effects of melatonin versus placebo on delirium in hip fracture patients: study protocol of a randomised, placebo-controlled, double blind trial. BMC Geriatr 11:34","journal-title":"BMC Geriatr"},{"issue":"1","key":"2975_CR29","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-019-1297-6","volume":"19","author":"AM Campbell","year":"2019","unstructured":"Campbell AM, Axon DR, Martin JR, Slack MK, Mollon L, Lee JK (2019) Melatonin for the prevention of postoperative delirium in older adults: a systematic review and meta-analysis. BMC Geriatr 19(1):272","journal-title":"BMC Geriatr"},{"issue":"9","key":"2975_CR30","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1007\/s00392-018-1241-3","volume":"107","author":"P Stachon","year":"2018","unstructured":"Stachon P, Kaier K, Zirlik A, Rein\u00f6hl J, Heidt T, Bothe W, Hehn P, Zehender M, Bode C, von Zur M\u00fchlen C (2018) Risk factors and outcome of postoperative delirium after transcatheter aortic valve replacement. Clin Res Cardiol 107(9):756\u2013762","journal-title":"Clin Res Cardiol"},{"issue":"1","key":"2975_CR31","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-24247-w","volume":"12","author":"G Guidry","year":"2022","unstructured":"Guidry G, Sparrow NA, Marshall HS, De Souza Santos R, Bharath SP, Gezalian MM, Pisarska MD, Vit JP, Kelly SA, Karumanchi SA et al (2022) 17\u03b2-estradiol ameliorates delirium-like phenotypes in a murine model of urinary tract infection. Sci Rep 12(1):19622","journal-title":"Sci Rep"},{"key":"2975_CR32","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14228113","author":"A Szewczak","year":"2025","unstructured":"Szewczak A, Siwicka D, Klukow J, Czerwik-Marcinkowska J, Zmorzynski S (2025) Clinical nursing management of adult patients with delirium in a hospital setting-a systematic review. J Clin Med. https:\/\/doi.org\/10.3390\/jcm14228113","journal-title":"J Clin Med"},{"issue":"5","key":"2975_CR33","doi-asserted-by":"publisher","first-page":"1508","DOI":"10.1111\/jgs.18751","volume":"72","author":"RS Penfold","year":"2024","unstructured":"Penfold RS, Squires C, Angus A, Shenkin SD, Ibitoye T, Tieges Z, Neufeld KJ, Avelino-Silva TJ, Davis D, Anand A et al (2024) Delirium detection tools show varying completion rates and positive score rates when used at scale in routine practice in general hospital settings: a systematic review. J Am Geriatr Soc 72(5):1508\u20131524","journal-title":"J Am Geriatr Soc"},{"issue":"8","key":"2975_CR34","doi-asserted-by":"publisher","first-page":"1837","DOI":"10.2337\/dc10-0102","volume":"33","author":"EA Nyenwe","year":"2010","unstructured":"Nyenwe EA, Razavi LN, Kitabchi AE, Khan AN, Wan JY (2010) Acidosis: the prime determinant of depressed sensorium in diabetic ketoacidosis. Diabetes Care 33(8):1837\u20131839","journal-title":"Diabetes Care"},{"issue":"6","key":"2975_CR35","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1089\/rej.2011.1185","volume":"14","author":"BC Munster","year":"2011","unstructured":"Munster BC, Aronica E, Zwinderman AH, Eikelenboom P, Cunningham C, Rooij SE (2011) Neuroinflammation in delirium: a postmortem case-control study. Rejuvenation Res 14(6):615\u2013622","journal-title":"Rejuvenation Res"},{"issue":"6","key":"2975_CR36","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1007\/s00401-010-0674-1","volume":"119","author":"J Cerejeira","year":"2010","unstructured":"Cerejeira J, Firmino H, Vaz-Serra A, Mukaetova-Ladinska EB (2010) The neuroinflammatory hypothesis of delirium. Acta Neuropathol 119(6):737\u2013754","journal-title":"Acta Neuropathol"},{"issue":"5","key":"2975_CR37","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1111\/j.1463-1326.2008.00987.x","volume":"11","author":"CL Allen","year":"2009","unstructured":"Allen CL, Bayraktutan U (2009) Antioxidants attenuate hyperglycaemia-mediated brain endothelial cell dysfunction and blood-brain barrier hyperpermeability. Diabetes Obes Metab 11(5):480\u2013490","journal-title":"Diabetes Obes Metab"},{"key":"2975_CR38","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2025.156471","volume":"176","author":"F D'Addio","year":"2026","unstructured":"D\u2019Addio F, Bucciarelli L, Lunati ME, Fiorina P (2026) Metabolic and immune dysfunction at the crossroads between type 1 diabetes and neurodegeneration. Metabolism 176:156471","journal-title":"Metabolism"},{"issue":"1","key":"2975_CR39","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1007\/s11605-020-04562-1","volume":"25","author":"A Ishihara","year":"2021","unstructured":"Ishihara A, Tanaka S, Ueno M, Iida H, Kaibori M, Nomi T, Hirokawa F, Ikoma H, Nakai T, Eguchi H et al (2021) Preoperative risk assessment for delirium after hepatic resection in the elderly: a prospective multicenter study. J Gastrointest Surg 25(1):134\u2013144","journal-title":"J Gastrointest Surg"},{"issue":"3","key":"2975_CR40","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1111\/j.1553-2712.2008.00339.x","volume":"16","author":"JH Han","year":"2009","unstructured":"Han JH, Zimmerman EE, Cutler N, Schnelle J, Morandi A, Dittus RS, Storrow AB, Ely EW (2009) Delirium in older emergency department patients: recognition, risk factors, and psychomotor subtypes. Acad Emerg Med 16(3):193\u2013200","journal-title":"Acad Emerg Med"},{"key":"2975_CR41","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.ejim.2025.01.008","volume":"134","author":"J Teixeira","year":"2025","unstructured":"Teixeira J, Pereira I, Castanho M, Sim\u00f5es do Couto F (2025) What is the impact of thiamine deficiency on cognitive function in patients with alcohol use disorder? - A systematic review. Eur J Intern Med 134:59\u201365","journal-title":"Eur J Intern Med"},{"issue":"6","key":"2975_CR42","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1097\/JNN.0000000000000543","volume":"52","author":"MA Mulkey","year":"2020","unstructured":"Mulkey MA, Olson DM (2020) Delirium tremens in the older adult. J Neurosci Nurs 52(6):316\u2013321","journal-title":"J Neurosci Nurs"},{"issue":"1","key":"2975_CR43","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1111\/ane.12671","volume":"135","author":"S Jesse","year":"2017","unstructured":"Jesse S, Br\u00e5then G, Ferrara M, Keindl M, Ben-Menachem E, Tanasescu R, Brodtkorb E, Hillbom M, Leone MA, Ludolph AC (2017) Alcohol withdrawal syndrome: mechanisms, manifestations, and management. Acta Neurol Scand 135(1):4\u201316","journal-title":"Acta Neurol Scand"},{"key":"2975_CR44","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2025.108036","volume":"222","author":"L Bucciarelli","year":"2025","unstructured":"Bucciarelli L, Cimino V, Dell\u2019Osso B, Fiorina P (2025) Psychotropic effects of GLP-1R agonists. Pharmacol Res 222:108036","journal-title":"Pharmacol Res"}],"container-title":["Journal of Endocrinological Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40618-026-02975-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40618-026-02975-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40618-026-02975-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T08:33:44Z","timestamp":1790757224000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40618-026-02975-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,8]]},"references-count":44,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2026,10]]}},"alternative-id":["2975"],"URL":"https:\/\/doi.org\/10.1007\/s40618-026-02975-4","relation":{},"ISSN":["1720-8386"],"issn-type":[{"value":"1720-8386","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,8]]},"assertion":[{"value":"30 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 June 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable.","order":1,"name":"Ethics","label":"Clinical trial number","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors report no conflicts of interest.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":3,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This observational study was deemed exempt by the Institutional Review Board of Zhanjiang Central Hospital, Guangdong Medical University that waived the need for consent because it used deidentified publicly available data.","order":4,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}}]}}