{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T02:31:21Z","timestamp":1793413881510,"version":"4.5.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Endocrinol Invest"],"DOI":"10.1007\/s40618-026-03017-9","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T11:09:07Z","timestamp":1786964947000},"page":"3203-3210","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Preimplantation genetic testing for male factor infertility: lights and shadows"],"prefix":"10.1007","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6707-3413","authenticated-orcid":false,"given":"Rossella","family":"Mazzilli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danilo","family":"Cimadomo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Capalbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Rosaria","family":"Campitiello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Guido","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Rienzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo Maria","family":"Ubaldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Vaiarelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Ferlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,17]]},"reference":[{"key":"3017_CR1","doi-asserted-by":"publisher","first-page":"1525","DOI":"10.1210\/jcem.79.6.7989450","volume":"79","author":"S Bhasin","year":"1994","unstructured":"Bhasin S, de Kretser DM, Baker HW (1994) Clinical review 64: pathophysiology and natural history of male infertility. J Clin Endocrinol Metab 79:1525\u20131529. https:\/\/doi.org\/10.1210\/jcem.79.6.7989450","journal-title":"J Clin Endocrinol Metab"},{"key":"3017_CR2","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.1007\/s40618-022-01741-6","volume":"45","author":"A Ferlin","year":"2022","unstructured":"Ferlin A, Calogero AE, Krausz C et al (2022) Management of male factor infertility: position statement from the Italian Society of Andrology and Sexual Medicine (SIAMS): endorsing organization: Italian Society of Embryology, Reproduction, and Research (SIERR). J Endocrinol Invest 45:1085\u20131113. https:\/\/doi.org\/10.1007\/s40618-022-01741-6","journal-title":"J Endocrinol Invest"},{"key":"3017_CR3","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1016\/S2213-8587(16)30040-7","volume":"5","author":"H Tournaye","year":"2017","unstructured":"Tournaye H, Krausz C, Oates RD (2017) Novel concepts in the aetiology of male reproductive impairment. Lancet Diabetes Endocrinol 5:544\u2013553. https:\/\/doi.org\/10.1016\/S2213-8587(16)30040-7","journal-title":"Lancet Diabetes Endocrinol"},{"key":"3017_CR4","volume-title":"WHO laboratory manual for the examination and processing of human semen","author":"World Health Organization","year":"2021","unstructured":"World Health Organization (2021) WHO laboratory manual for the examination and processing of human semen, 6th edn. World Health Organization, Geneva","edition":"6th edn"},{"key":"3017_CR5","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2020.591837","volume":"11","author":"A Garolla","year":"2021","unstructured":"Garolla A, Pizzol D, Carosso AR et al (2021) Practical clinical and diagnostic pathway for the investigation of the infertile couple. Front Endocrinol (Lausanne) 11:591837. https:\/\/doi.org\/10.3389\/fendo.2020.591837","journal-title":"Front Endocrinol (Lausanne)"},{"key":"3017_CR6","doi-asserted-by":"publisher","first-page":"2122","DOI":"10.1111\/andr.70006","volume":"13","author":"G Grande","year":"2025","unstructured":"Grande G, Garolla A, Graziani A et al (2025) Comprehensive diagnostic and therapeutic approach to male factor infertility aimed at natural fertility: a multicentric retrospective cohort study. Andrology 13:2122\u20132130. https:\/\/doi.org\/10.1111\/andr.70006","journal-title":"Andrology"},{"key":"3017_CR7","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1007\/s40618-022-02000-4","volume":"46","author":"R Mazzilli","year":"2023","unstructured":"Mazzilli R, Rucci C, Vaiarelli A et al (2023) Male factor infertility and assisted reproductive technologies: indications, minimum access criteria and outcomes. J Endocrinol Invest 46:1079\u20131085. https:\/\/doi.org\/10.1007\/s40618-022-02000-4","journal-title":"J Endocrinol Invest"},{"key":"3017_CR8","doi-asserted-by":"publisher","DOI":"10.1093\/hropen\/hoaa021","author":"F Carvalho","year":"2020","unstructured":"Carvalho F, Coonen E, Goossens V et al (2020) ESHRE PGT consortium good practice recommendations for the organisation of PGT. Hum Reprod Open. https:\/\/doi.org\/10.1093\/hropen\/hoaa021","journal-title":"Hum Reprod Open"},{"key":"3017_CR9","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1038\/s41431-017-0016-z","volume":"26","author":"JC Harper","year":"2018","unstructured":"Harper JC, Aittom\u00e4ki K, Borry P et al (2018) Recent developments in genetics and medically assisted reproduction: from research to clinical applications. Eur J Hum Genet 26:12\u201333. https:\/\/doi.org\/10.1038\/s41431-017-0016-z","journal-title":"Eur J Hum Genet"},{"key":"3017_CR10","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1093\/humrep\/deu033","volume":"29","author":"A Capalbo","year":"2014","unstructured":"Capalbo A, Rienzi L, Cimadomo D et al (2014) Correlation between standard blastocyst morphology, euploidy and implantation: an observational study in two centers involving 956 screened blastocysts. Hum Reprod 29:1173\u20131181. https:\/\/doi.org\/10.1093\/humrep\/deu033","journal-title":"Hum Reprod"},{"key":"3017_CR11","doi-asserted-by":"publisher","DOI":"10.3791\/59625","volume":"149","author":"R Maggiulli","year":"2019","unstructured":"Maggiulli R, Giancani A, Cimadomo D et al (2019) Human blastocyst biopsy and vitrification. J Vis Exp 149:e59625. https:\/\/doi.org\/10.3791\/59625","journal-title":"J Vis Exp"},{"key":"3017_CR12","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1007\/s10815-016-0785-2","volume":"33","author":"A Vaiarelli","year":"2016","unstructured":"Vaiarelli A, Cimadomo D, Capalbo A et al (2016) Pre-implantation genetic testing in ART: who will benefit and what is the evidence? J Assist Reprod Genet 33:1273\u20131278. https:\/\/doi.org\/10.1007\/s10815-016-0785-2","journal-title":"J Assist Reprod Genet"},{"key":"3017_CR13","first-page":"31","volume":"3","author":"L Gianaroli","year":"1997","unstructured":"Gianaroli L, Munn\u00e9 S, Magli MC, Ferraretti AP (1997) Preimplantation genetic diagnosis of aneuploidy and male infertility. Int J Androl Suppl 3:31\u201334","journal-title":"Int J Androl Suppl"},{"key":"3017_CR14","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1016\/S1472-6483(10)60131-9","volume":"18","author":"MC Magli","year":"2009","unstructured":"Magli MC, Gianaroli L, Ferraretti AP et al (2009) Paternal contribution to aneuploidy in preimplantation embryos. Reprod Biomed Online 18:536\u2013542. https:\/\/doi.org\/10.1016\/S1472-6483(10)60131-9","journal-title":"Reprod Biomed Online"},{"key":"3017_CR15","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.3390\/biomedicines13051191","volume":"13","author":"M Ismayilova","year":"2025","unstructured":"Ismayilova M, Hasanova A, Semikhodskii A (2025) Preimplantation testing of human blastomeres for aneuploidy increases IVF success in couples where male partners had abnormal semen parameters. Biomedicines 13:1191. https:\/\/doi.org\/10.3390\/biomedicines13051191","journal-title":"Biomedicines"},{"key":"3017_CR16","doi-asserted-by":"publisher","first-page":"2047","DOI":"10.1007\/s10815-019-01584-w","volume":"36","author":"N Tarozzi","year":"2019","unstructured":"Tarozzi N, Nadalini M, Lagalla C et al (2019) Male factor infertility impacts the rate of mosaic blastocysts in cycles of preimplantation genetic testing for aneuploidy. J Assist Reprod Genet 36:2047\u20132055. https:\/\/doi.org\/10.1007\/s10815-019-01584-w","journal-title":"J Assist Reprod Genet"},{"key":"3017_CR17","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1016\/j.fertnstert.2017.08.033","volume":"108","author":"R Mazzilli","year":"2017","unstructured":"Mazzilli R, Cimadomo D, Vaiarelli A et al (2017) Effect of the male factor on the clinical outcome of intracytoplasmic sperm injection combined with preimplantation aneuploidy testing: observational longitudinal cohort study of 1,219 consecutive cycles. Fertil Steril 108:961-972.e3. https:\/\/doi.org\/10.1016\/j.fertnstert.2017.08.033","journal-title":"Fertil Steril"},{"key":"3017_CR18","doi-asserted-by":"publisher","first-page":"1745","DOI":"10.1111\/andr.13811","volume":"13","author":"R Mazzilli","year":"2025","unstructured":"Mazzilli R, Cimadomo D, Innocenti F et al (2025) A WHO 2021-based comprehensive scheme outlining sperm parameters\u2019 associations with IVF outcomes in PGT-A cycles. Andrology 13:1745\u20131756. https:\/\/doi.org\/10.1111\/andr.13811","journal-title":"Andrology"},{"key":"3017_CR19","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/j.fertnstert.2022.04.020","volume":"118","author":"ML Bonus","year":"2022","unstructured":"Bonus ML, McQueen DB, Ruderman R et al (2022) Relationship between paternal factors and embryonic aneuploidy of paternal origin. Fertil Steril 118:281\u2013288. https:\/\/doi.org\/10.1016\/j.fertnstert.2022.04.020","journal-title":"Fertil Steril"},{"key":"3017_CR20","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.fertnstert.2025.02.014","volume":"124","author":"W Wang","year":"2025","unstructured":"Wang W, Lu J, Li Z et al (2025) Preimplantation genetic testing for aneuploidy does not benefit couples with male factor infertility. Fertil Steril 124:153\u2013155. https:\/\/doi.org\/10.1016\/j.fertnstert.2025.02.014","journal-title":"Fertil Steril"},{"key":"3017_CR21","doi-asserted-by":"publisher","first-page":"1282","DOI":"10.1093\/humrep\/deaf080","volume":"40","author":"M Cozzolino","year":"2025","unstructured":"Cozzolino M, Pellegrini L, Ottolini CS et al (2025) The clinical impact of oligozoospermia in oocyte donation ICSI cycles using preimplantation genetic test for aneuploidy. Hum Reprod 40:1282\u20131290. https:\/\/doi.org\/10.1093\/humrep\/deaf080","journal-title":"Hum Reprod"},{"key":"3017_CR22","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1016\/j.fertnstert.2015.06.033","volume":"104","author":"A Coates","year":"2015","unstructured":"Coates A, Hesla JS, Hurliman A et al (2015) Use of suboptimal sperm increases the risk of aneuploidy of the sex chromosomes in preimplantation blastocyst embryos. Fertil Steril 104:866\u2013872. https:\/\/doi.org\/10.1016\/j.fertnstert.2015.06.033","journal-title":"Fertil Steril"},{"key":"3017_CR23","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.1093\/humrep\/dey110","volume":"33","author":"R Mazzilli","year":"2018","unstructured":"Mazzilli R, Cimadomo D, Rienzi L et al (2018) Prevalence of XXY karyotypes in human blastocysts: multicentre data from 7549 trophectoderm biopsies obtained during preimplantation genetic testing cycles in IVF. Hum Reprod 33:1355\u20131363. https:\/\/doi.org\/10.1093\/humrep\/dey110","journal-title":"Hum Reprod"},{"key":"3017_CR24","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1016\/j.rbmo.2020.06.015","volume":"41","author":"MR Asoglu","year":"2020","unstructured":"Asoglu MR, Celik C, Serefoglu EC et al (2020) Preimplantation genetic testing for aneuploidy in severe male factor infertility. Reprod Biomed Online 41:595\u2013603. https:\/\/doi.org\/10.1016\/j.rbmo.2020.06.015","journal-title":"Reprod Biomed Online"},{"key":"3017_CR25","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1093\/humrep\/dey357","volume":"34","author":"D Paoli","year":"2019","unstructured":"Paoli D, Pecora G, Pallotti F et al (2019) Cytological and molecular aspects of the ageing sperm. Hum Reprod 34:218\u2013227. https:\/\/doi.org\/10.1093\/humrep\/dey357","journal-title":"Hum Reprod"},{"key":"3017_CR26","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1093\/humupd\/dmac033","volume":"29","author":"V Ashapkin","year":"2023","unstructured":"Ashapkin V, Suvorov A, Pilsner JR et al (2023) Age-associated epigenetic changes in mammalian sperm: implications for offspring health and development. Hum Reprod Update 29:24\u201344. https:\/\/doi.org\/10.1093\/humupd\/dmac033","journal-title":"Hum Reprod Update"},{"key":"3017_CR27","doi-asserted-by":"publisher","first-page":"35","DOI":"10.3389\/fendo.2019.00035","volume":"10","author":"M Gallo","year":"2019","unstructured":"Gallo M, Licata E, Meneghini C et al (2019) Impact of paternal age on seminal parameters and reproductive outcome of intracytoplasmatic sperm injection in infertile Italian women. Front Endocrinol (Lausanne) 10:35. https:\/\/doi.org\/10.3389\/fendo.2019.00035","journal-title":"Front Endocrinol (Lausanne)"},{"key":"3017_CR28","doi-asserted-by":"publisher","first-page":"1897","DOI":"10.1007\/s10815-018-1256-8","volume":"35","author":"A Bartolacci","year":"2018","unstructured":"Bartolacci A, Pagliardini L, Makieva S et al (2018) Abnormal sperm concentration and motility as well as advanced paternal age compromise early embryonic development but not pregnancy outcomes: a retrospective study of 1266 ICSI cycles. J Assist Reprod Genet 35:1897\u20131903. https:\/\/doi.org\/10.1007\/s10815-018-1256-8","journal-title":"J Assist Reprod Genet"},{"key":"3017_CR29","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1111\/andr.13385","volume":"11","author":"A Gourinat","year":"2023","unstructured":"Gourinat A, Mazeaud C, Hubert J et al (2023) Impact of paternal age on assisted reproductive technology outcomes and offspring health: a systematic review. Andrology 11:973\u2013986. https:\/\/doi.org\/10.1111\/andr.13385","journal-title":"Andrology"},{"key":"3017_CR30","doi-asserted-by":"publisher","first-page":"26","DOI":"10.5935\/1518-0557.20180004","volume":"22","author":"J Garc\u00eda-Ferreyra","year":"2018","unstructured":"Garc\u00eda-Ferreyra J, Hilario R, Due\u00f1as J (2018) High percentages of embryos with 21, 18 or 13 trisomy are related to advanced paternal age in donor egg cycles. JBRA Assist Reprod 22:26\u201334. https:\/\/doi.org\/10.5935\/1518-0557.20180004","journal-title":"JBRA Assist Reprod"},{"key":"3017_CR31","doi-asserted-by":"publisher","first-page":"2039","DOI":"10.1007\/s10815-019-01549-z","volume":"36","author":"RJ Carrasquillo","year":"2019","unstructured":"Carrasquillo RJ, Kohn TP, Cinnioglu C et al (2019) Advanced paternal age does not affect embryo aneuploidy following blastocyst biopsy in egg donor cycles. J Assist Reprod Genet 36:2039\u20132045. https:\/\/doi.org\/10.1007\/s10815-019-01549-z","journal-title":"J Assist Reprod Genet"},{"key":"3017_CR32","doi-asserted-by":"publisher","first-page":"22","DOI":"10.5653\/cerm.2019.46.1.22","volume":"46","author":"MK Kim","year":"2019","unstructured":"Kim MK, Park JK, Jeon Y et al (2019) Effects of paternal age on human embryo development in in vitro fertilization with preimplantation genetic screening. Clin Exp Reprod Med 46:22\u201329. https:\/\/doi.org\/10.5653\/cerm.2019.46.1.22","journal-title":"Clin Exp Reprod Med"},{"key":"3017_CR33","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/j.fertnstert.2020.03.034","volume":"114","author":"M Dviri","year":"2020","unstructured":"Dviri M, Madjunkova S, Koziarz A et al (2020) Is there a correlation between paternal age and aneuploidy rate? An analysis of 3,118 embryos derived from young egg donors. Fertil Steril 114:293\u2013300. https:\/\/doi.org\/10.1016\/j.fertnstert.2020.03.034","journal-title":"Fertil Steril"},{"key":"3017_CR34","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1016\/j.fertnstert.2025.06.029","volume":"124","author":"I Elkhatib","year":"2025","unstructured":"Elkhatib I, Nogueira D, Bayram A et al (2025) The influence of male age and sperm parameters on blastulation and euploidy rates. Fertil Steril 124:1006\u20131015. https:\/\/doi.org\/10.1016\/j.fertnstert.2025.06.029","journal-title":"Fertil Steril"},{"key":"3017_CR35","doi-asserted-by":"publisher","first-page":"306","DOI":"10.5935\/1518-0557.20230076","volume":"28","author":"SW Andrabi","year":"2024","unstructured":"Andrabi SW, Ara A, Saharan A et al (2024) Sperm DNA fragmentation: causes, evaluation and management in male infertility. JBRA Assist Reprod 28:306\u2013319. https:\/\/doi.org\/10.5935\/1518-0557.20230076","journal-title":"JBRA Assist Reprod"},{"key":"3017_CR36","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1093\/molehr\/2.1.46","volume":"2","author":"MJ Ashwood-Smith","year":"1996","unstructured":"Ashwood-Smith MJ, Edwards RG (1996) DNA repair by oocytes. Mol Hum Reprod 2:46\u201351. https:\/\/doi.org\/10.1093\/molehr\/2.1.46","journal-title":"Mol Hum Reprod"},{"key":"3017_CR37","doi-asserted-by":"publisher","first-page":"1922","DOI":"10.1093\/humrep\/des148","volume":"27","author":"F Bronet","year":"2012","unstructured":"Bronet F, Mart\u00ednez E, Gayt\u00e1n M et al (2012) Sperm DNA fragmentation index does not correlate with the sperm or embryo aneuploidy rate in recurrent miscarriage or implantation failure patients. Hum Reprod 27:1922\u20131929. https:\/\/doi.org\/10.1093\/humrep\/des148","journal-title":"Hum Reprod"},{"key":"3017_CR38","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1080\/09513590.2017.1379500","volume":"34","author":"I Gat","year":"2018","unstructured":"Gat I, Li N, Yasovich N et al (2018) Sperm DNA fragmentation index does not correlate with blastocyst euploidy rate in egg donor cycles. Gynecol Endocrinol 34:212\u2013216. https:\/\/doi.org\/10.1080\/09513590.2017.1379500","journal-title":"Gynecol Endocrinol"},{"key":"3017_CR39","doi-asserted-by":"publisher","DOI":"10.1111\/andr.70079","author":"P Kong","year":"2026","unstructured":"Kong P, Liang S, Pan J et al (2026) Sperm SCSA DNA fragmentation index does not influence the euploidy rate of viable blastocysts in advanced-age women. Andrology. https:\/\/doi.org\/10.1111\/andr.70079","journal-title":"Andrology"},{"key":"3017_CR40","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2023.103366","volume":"47","author":"W Fu","year":"2023","unstructured":"Fu W, Cui Q, Yang Z et al (2023) High sperm DNA fragmentation increased embryo aneuploidy rate in patients undergoing preimplantation genetic testing. Reprod Biomed Online 47:103366. https:\/\/doi.org\/10.1016\/j.rbmo.2023.103366","journal-title":"Reprod Biomed Online"},{"key":"3017_CR41","doi-asserted-by":"publisher","DOI":"10.1186\/s40001-025-03402-9","volume":"30","author":"B Wan","year":"2025","unstructured":"Wan B, Fu Y, Ma N et al (2025) Effect of sperm DNA fragmentation on embryo euploidy rate in assisted reproductive technologies: a systematic review and meta-analysis. Eur J Med Res 30:1138. https:\/\/doi.org\/10.1186\/s40001-025-03402-9","journal-title":"Eur J Med Res"},{"key":"3017_CR42","doi-asserted-by":"publisher","first-page":"1516","DOI":"10.1093\/humrep\/dep037","volume":"24","author":"M S\u00e1nchez-Castro","year":"2009","unstructured":"S\u00e1nchez-Castro M, Jim\u00e9nez-Macedo AR, Sandalinas M et al (2009) Prognostic value of sperm fluorescence in situ hybridization analysis over PGD. Hum Reprod 24:1516\u20131521. https:\/\/doi.org\/10.1093\/humrep\/dep037","journal-title":"Hum Reprod"},{"key":"3017_CR43","doi-asserted-by":"publisher","first-page":"2084","DOI":"10.1093\/humrep\/16.10.2084","volume":"16","author":"C Rubio","year":"2001","unstructured":"Rubio C, Gil-Salom M, Sim\u00f3n C et al (2001) Incidence of sperm chromosomal abnormalities in a risk population: relationship with sperm quality and ICSI outcome. Hum Reprod 16:2084\u20132092. https:\/\/doi.org\/10.1093\/humrep\/16.10.2084","journal-title":"Hum Reprod"},{"key":"3017_CR44","doi-asserted-by":"publisher","DOI":"10.1093\/hropen\/hoaa017","author":"E Coonen","year":"2020","unstructured":"Coonen E, Rubio C, Christopikou D et al (2020) ESHRE PGT Consortium good practice recommendations for the detection of structural and numerical chromosomal aberrations. Hum Reprod Open. https:\/\/doi.org\/10.1093\/hropen\/hoaa017","journal-title":"Hum Reprod Open"}],"container-title":["Journal of Endocrinological Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40618-026-03017-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40618-026-03017-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40618-026-03017-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T02:02:16Z","timestamp":1793412136000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40618-026-03017-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,17]]},"references-count":44,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2026,11]]}},"alternative-id":["3017"],"URL":"https:\/\/doi.org\/10.1007\/s40618-026-03017-9","relation":{},"ISSN":["1720-8386"],"issn-type":[{"value":"1720-8386","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,17]]},"assertion":[{"value":"23 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 August 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 August 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"None.","order":1,"name":"Ethics","label":"Conflicts of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None.","order":2,"name":"Ethics","label":"Research involving Human Participants and\/or Animals","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":3,"name":"Ethics","label":"Informed consent","group":{"name":"EthicsHeading","label":"Declarations"}}]}}